|
US5853719A
(en)
*
|
1996-04-30 |
1998-12-29 |
Duke University |
Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA
|
|
US7585622B1
(en)
|
1996-10-01 |
2009-09-08 |
Geron Corporation |
Increasing the proliferative capacity of cells using telomerase reverse transcriptase
|
|
US6475789B1
(en)
*
|
1996-10-01 |
2002-11-05 |
University Technology Corporation |
Human telomerase catalytic subunit: diagnostic and therapeutic methods
|
|
WO1998014593A2
(en)
|
1996-10-01 |
1998-04-09 |
Geron Corporation |
Human telomerase catalytic subunit
|
|
US6228640B1
(en)
|
1997-02-07 |
2001-05-08 |
Cem Cezayirli |
Programmable antigen presenting cell of CD34 lineage
|
|
US6251665B1
(en)
*
|
1997-02-07 |
2001-06-26 |
Cem Cezayirli |
Directed maturation of stem cells and production of programmable antigen presenting dentritic cells therefrom
|
|
US6977073B1
(en)
|
1997-02-07 |
2005-12-20 |
Cem Cezayirli |
Method for stimulating an immune response
|
|
US20050169898A1
(en)
*
|
1997-04-15 |
2005-08-04 |
Jianlin Gong |
Cell fusions and methods of making and using the same
|
|
US20020041868A1
(en)
*
|
1997-04-15 |
2002-04-11 |
Charles Nicolette |
Cell fusions and methods of making and using the same
|
|
US7413864B2
(en)
*
|
1997-04-18 |
2008-08-19 |
Geron Corporation |
Treating cancer using a telomerase vaccine
|
|
US7622549B2
(en)
*
|
1997-04-18 |
2009-11-24 |
Geron Corporation |
Human telomerase reverse transcriptase polypeptides
|
|
US6977074B2
(en)
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
WO1999050392A1
(en)
|
1998-03-31 |
1999-10-07 |
Geron Corporation |
Methods and compositions for eliciting an immune response to a telomerase antigen
|
|
US6337200B1
(en)
*
|
1998-03-31 |
2002-01-08 |
Geron Corporation |
Human telomerase catalytic subunit variants
|
|
US7402307B2
(en)
*
|
1998-03-31 |
2008-07-22 |
Geron Corporation |
Method for identifying and killing cancer cells
|
|
US20030022854A1
(en)
*
|
1998-06-25 |
2003-01-30 |
Dow Steven W. |
Vaccines using nucleic acid-lipid complexes
|
|
US20040247662A1
(en)
*
|
1998-06-25 |
2004-12-09 |
Dow Steven W. |
Systemic immune activation method using nucleic acid-lipid complexes
|
|
FR2785542B1
(fr)
*
|
1998-11-06 |
2001-02-09 |
Pf Medicament |
UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES
|
|
US7713739B1
(en)
*
|
2000-11-17 |
2010-05-11 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticle-based transfection and activation of dendritic cells
|
|
US7015204B1
(en)
|
1999-10-07 |
2006-03-21 |
Cornell Research Foundation, Inc. |
Protective immunity or immunological tolerance induced with RNA particularly total cellular RNA
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US7541184B2
(en)
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US6783939B2
(en)
*
|
2000-07-07 |
2004-08-31 |
Alphavax, Inc. |
Alphavirus vectors and virosomes with modified HIV genes for use in vaccines
|
|
JP2004532625A
(ja)
*
|
2000-10-24 |
2004-10-28 |
ホワイトヘッド インスチチュート フォアー バイオメディカル リサーチ |
多種多様な病原体に対する樹状細胞の応答
|
|
US20030059834A1
(en)
*
|
2001-02-01 |
2003-03-27 |
Chang Nancy T. |
Methods to generate and identify monoclonal antibodies to a large number of human antigens
|
|
DE10112851C1
(de)
|
2001-03-16 |
2002-10-10 |
Gsf Forschungszentrum Umwelt |
Semi-allogene Antitumor-Vakzine mit HLA-haplo-identischen Antigen-präsentierenden Zellen
|
|
WO2002087627A1
(en)
*
|
2001-04-27 |
2002-11-07 |
Xcyte Therapies, Inc. |
Maturation of antigen-presenting cells using activated t cells
|
|
GB0111015D0
(en)
*
|
2001-05-04 |
2001-06-27 |
Norsk Hydro As |
Genetic material
|
|
EP1604688B1
(de)
|
2001-06-05 |
2010-02-03 |
CureVac GmbH |
Stabilisierte Tumorantigen-mRNA mit erhöhtem G/C-Gehalt
|
|
DE60233061D1
(de)
*
|
2001-09-06 |
2009-09-03 |
Alphavax Inc |
Alphavirus replikon-vektorsysteme
|
|
EP1442125A4
(en)
*
|
2001-10-04 |
2004-12-08 |
Carlos Estuard Aguilar-Cordova |
CHIMERAL VIRUS VECTORS FOR GENE THERAPY
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
KR20050047518A
(ko)
*
|
2002-07-05 |
2005-05-20 |
듀크 유니버시티 |
혈관 면역요법
|
|
AU2003278709A1
(en)
*
|
2002-08-14 |
2004-03-03 |
Duke University |
Method of enhancing cd4+ t cell responses
|
|
ES2327040T3
(es)
|
2002-09-12 |
2009-10-23 |
Oncotherapy Science, Inc. |
Peptidos kdr y vacunas que los contienen.
|
|
US7785583B2
(en)
*
|
2002-12-10 |
2010-08-31 |
Argos Therapeutics, Inc. |
In situ maturation of dendritic cells
|
|
BR122019005271B1
(pt)
*
|
2002-12-13 |
2020-10-13 |
Alphavax, Inc. |
método para a preparação de partículas de replicon de alfavírus (arps)
|
|
JP4991108B2
(ja)
*
|
2002-12-13 |
2012-08-01 |
アルファバックス，インコーポレイティド |
多抗原性アルファウイルス・レプリコン粒子及び方法
|
|
WO2004074451A2
(en)
*
|
2003-02-18 |
2004-09-02 |
Maxcyte, Inc. |
Loading of cells with antigens by electroporation
|
|
US20060134067A1
(en)
*
|
2003-02-18 |
2006-06-22 |
Maxcyte, Inc. |
Loading of cells with antigens by electroporation
|
|
CA2516320C
(en)
|
2003-02-18 |
2015-05-26 |
Kevin Slawin |
Induced activation in dendritic cells
|
|
JP5016305B2
(ja)
*
|
2003-03-20 |
2012-09-05 |
アルファヴァックス，インコーポレイテッド |
改良されたアルファウイルスレプリコンおよびヘルパー構築物
|
|
DE602004021260D1
(de)
*
|
2003-07-11 |
2009-07-09 |
Alphavax Inc |
Cytomegalovirusimpfstoffe, die auf dem alphavirus basieren
|
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
|
EP1697396A4
(en)
*
|
2003-11-25 |
2008-05-28 |
Argos Therapeutics Inc |
MRNA-TRANSFIED ANTIGEN-PRESENTING CELLS
|
|
US20050181035A1
(en)
*
|
2004-02-17 |
2005-08-18 |
Dow Steven W. |
Systemic immune activation method using non CpG nucleic acids
|
|
WO2005084387A2
(en)
*
|
2004-03-02 |
2005-09-15 |
Tsuneya Ohno |
Methods and compositions for hybrid cell vaccines for the treatment and prevention of cancer
|
|
CN1989250B
(zh)
|
2004-05-18 |
2013-11-20 |
阿尔法瓦克斯公司 |
Tc-83衍生的甲病毒属载体、颗粒和方法
|
|
US20080293581A1
(en)
*
|
2004-05-24 |
2008-11-27 |
Rogler Charles E |
Rna Expression Microarrays
|
|
CA2504451A1
(en)
*
|
2004-08-10 |
2006-02-10 |
Geron Corporation |
Dendritic cell vaccines for treating cancer made from embryonic stem cells
|
|
WO2006031870A2
(en)
|
2004-09-14 |
2006-03-23 |
Argos Therapeutics, Inc. |
Strain independent amplification of pathogens and vaccines thereto
|
|
US8076132B2
(en)
|
2004-09-17 |
2011-12-13 |
Hasumi International Research Foundation |
Dendritic cell tumor injection (DCTI) therapy
|
|
US20060216269A1
(en)
*
|
2004-09-17 |
2006-09-28 |
Kenichiro Hasumi |
Dendritic cell tumor injection (DCTI) therapy
|
|
GB0501129D0
(en)
*
|
2005-01-19 |
2005-02-23 |
Ribostem Ltd |
Method of treatment by administration of RNA
|
|
DK2325305T3
(en)
|
2005-02-25 |
2014-03-03 |
Oncotherapy Science Inc |
Peptide vaccines for cancers that express TTK-, URLC10- or KOC1 polypeptide
|
|
DK2095822T3
(da)
|
2005-02-28 |
2014-01-13 |
Oncotherapy Science Inc |
Epitoppeptider afledt af karendothelvækstfaktorreceptor-1 samt vacciner indeholdende disse peptider
|
|
WO2006127150A2
(en)
|
2005-04-08 |
2006-11-30 |
Argos Therapeutics, Inc. |
Dendritic cell compositions and methods
|
|
BRPI0613970B8
(pt)
|
2005-07-27 |
2021-05-25 |
Oncotherapy Science Inc |
composição para o tratamento ou para a prevenção de câncer de cólon compreende uma quantidade farmaceuticamente eficaz de um sirna contra um polinucleotídeo de tom 34
|
|
AU2006304573B2
(en)
|
2005-10-17 |
2012-05-24 |
Sloan Kettering Institute For Cancer Research |
WT1 HLA class II-binding peptides and compositions and methods comprising same
|
|
EP3117836A1
(en)
|
2006-04-10 |
2017-01-18 |
Sloan Kettering Institute For Cancer Research |
Immunogenic wt-1 peptides and uses thereof
|
|
US20070281336A1
(en)
*
|
2006-04-14 |
2007-12-06 |
Epicentre Technologies |
Kits and methods for generating 5' capped RNA
|
|
AU2007288368B2
(en)
|
2006-08-18 |
2013-07-04 |
Coimmune, Inc. |
Use of CD83 in combination therapies
|
|
KR101493773B1
(ko)
|
2006-10-17 |
2015-03-03 |
온코세라피 사이언스 가부시키가이샤 |
Ｍｐｈｏｓｐｈ1 또는 ｄｅｐｄｃ1 폴리펩티드를 발현하는 암에 대한 펩티드 백신
|
|
WO2008049113A2
(en)
*
|
2006-10-19 |
2008-04-24 |
Baylor College Of Medicine |
Generating an immune response by inducing cd40 and pattern recognition receptors
|
|
WO2008055354A1
(en)
*
|
2006-11-10 |
2008-05-15 |
Université de Montréal |
Rna-loaded dendritic cell compositions for eliciting cd4+ t cell help and related methods
|
|
TWI494319B
(zh)
|
2007-02-21 |
2015-08-01 |
Oncotherapy Science Inc |
表現腫瘤相關抗原之癌症的胜肽疫苗
|
|
TWI434853B
(zh)
|
2007-04-11 |
2014-04-21 |
Oncotherapy Science Inc |
腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗
|
|
JP5602624B2
(ja)
|
2007-06-21 |
2014-10-08 |
アルファバックス， インコーポレイテッド |
αウイルス構造タンパク質の発現のためのプロモーターレスカセット
|
|
EP4032899A1
(en)
|
2007-08-20 |
2022-07-27 |
Oncotherapy Science, Inc. |
Foxm1 peptide and medicinal agent comprising the same
|
|
US8513208B2
(en)
*
|
2008-02-28 |
2013-08-20 |
Argos Therapeutics, Inc. |
Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection
|
|
DK3156069T3
(da)
|
2008-06-20 |
2020-09-21 |
Univ Duke |
Sammensætninger, fremgangsmåder, og kits til fremkaldelse af et immunrespons
|
|
JP6133538B2
(ja)
|
2008-09-22 |
2017-05-24 |
ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ |
Ｃｄ４０およびパターン認識受容体アダプターを誘発することによる免疫応答を生成するための方法および組成物
|
|
DK2352756T3
(da)
|
2008-11-24 |
2012-12-03 |
Helmholtz Zentrum Muenchen |
Højaffin T-cellereceptor og anvendelse af denne
|
|
TWI539160B
(zh)
|
2008-12-05 |
2016-06-21 |
腫瘤療法 科學股份有限公司 |
Ｗｄｒｐｕｈ抗原決定位胜肽以及含此胜肽之疫苗
|
|
US8728806B2
(en)
|
2008-12-06 |
2014-05-20 |
The Board Of Regents, The University Of Texas System |
Methods and compositions related to Th-1 dendritic cells
|
|
TWI469791B
(zh)
|
2009-02-18 |
2015-01-21 |
Oncotherapy Science Inc |
Ｆｏｘｍ１胜肽以及含此胜肽之疫苗
|
|
RU2600888C2
(ru)
|
2009-03-18 |
2016-10-27 |
Онкотерапи Сайенс, Инк. |
Пептиды neil3 и включающие их вакцины
|
|
TWI507204B
(zh)
|
2009-05-26 |
2015-11-11 |
Oncotherapy Science Inc |
Ｃｄｃ４５ｌ胜肽與含此胜肽之疫苗
|
|
TW201136604A
(en)
|
2009-12-14 |
2011-11-01 |
Oncotherapy Science Inc |
TMEM22 peptides and vaccines including the same
|
|
BR112012022641A2
(pt)
|
2010-03-11 |
2017-02-14 |
Oncotherapy Science Inc |
peptídeos hjurp e vacinas que incluem os mesmos
|
|
TWI538685B
(zh)
|
2010-04-02 |
2016-06-21 |
腫瘤療法 科學股份有限公司 |
Ｅｃｔ２胜肽及含此胜肽之疫苗
|
|
WO2011146862A1
(en)
|
2010-05-21 |
2011-11-24 |
Bellicum Pharmaceuticals, Inc. |
Methods for inducing selective apoptosis
|
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP3590949B1
(en)
|
2010-10-01 |
2022-05-18 |
ModernaTX, Inc. |
Ribonucleic acids containing n1-methyl-pseudouracils and uses thereof
|
|
AU2012236099A1
(en)
|
2011-03-31 |
2013-10-03 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
EP2557089A2
(en)
|
2011-07-15 |
2013-02-13 |
Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) |
Compositions and methods for immunomodulation
|
|
BR112014001363B1
(pt)
|
2011-08-12 |
2021-06-01 |
Oncotherapy Science, Inc. |
Composições para indução de um linfócito t citotóxico (ctl), para indução de uma célula apresentadora de antígeno (apc) tendo capacidade de indução de ctl, composição farmacêutica, métodos in vitro para indução de apc e de ctl, usos de peptídeos e vetor
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
RS62993B1
(sr)
|
2011-10-03 |
2022-03-31 |
Modernatx Inc |
Modifikovani nukleozidi, nukleotidi, i nukleinske kiseline, i njihove upotrebe
|
|
AU2012329502B2
(en)
|
2011-10-28 |
2016-11-24 |
Oncotherapy Science, Inc. |
TOPK peptides and vaccines including the same
|
|
AU2012352180A1
(en)
|
2011-12-16 |
2014-07-31 |
Moderna Therapeutics, Inc. |
Modified nucleoside, nucleotide, and nucleic acid compositions
|
|
EP3520810A3
(en)
|
2012-01-13 |
2019-11-06 |
Memorial Sloan-Kettering Cancer Center |
Immunogenic wt1 peptides and use thereof
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
JP2015513912A
(ja)
|
2012-04-02 |
2015-05-18 |
モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
タンパク質の産生のための修飾ポリヌクレオチド
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
EP2872530A4
(en)
|
2012-07-10 |
2016-04-06 |
Oncotherapy Science Inc |
KIF20A EPITOPE PEPTIDES FOR TH1 CELLS AND VACCINES CONTAINING SAME
|
|
PL2922554T3
(pl)
|
2012-11-26 |
2022-06-20 |
Modernatx, Inc. |
Na zmodyfikowany na końcach
|
|
WO2014113490A2
(en)
|
2013-01-15 |
2014-07-24 |
Memorial Sloan Kettering Cancer Center |
Immunogenic wt-1 peptides and methods of use thereof
|
|
US10815273B2
(en)
|
2013-01-15 |
2020-10-27 |
Memorial Sloan Kettering Cancer Center |
Immunogenic WT-1 peptides and methods of use thereof
|
|
US9434935B2
(en)
|
2013-03-10 |
2016-09-06 |
Bellicum Pharmaceuticals, Inc. |
Modified caspase polypeptides and uses thereof
|
|
TWI658049B
(zh)
|
2013-03-12 |
2019-05-01 |
腫瘤療法 科學股份有限公司 |
Ｋｎｔｃ２胜肽及含此胜肽之疫苗
|
|
WO2014151960A2
(en)
|
2013-03-14 |
2014-09-25 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlling t cell proliferation
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
ES2791598T3
(es)
|
2013-06-05 |
2020-11-05 |
Bellicum Pharmaceuticals Inc |
Métodos para inducir apoptosis parcial utilizando polipéptidos de caspasa
|
|
WO2015047901A1
(en)
|
2013-09-24 |
2015-04-02 |
Duke University |
Compositions, methods and kits for eliciting an immune response
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
CN105980401A
(zh)
|
2013-10-03 |
2016-09-28 |
现代治疗公司 |
编码低密度脂蛋白受体的多核苷酸
|
|
CA2925021C
(en)
|
2013-11-01 |
2025-05-06 |
Curevac Ag |
MODIFIED MESSENGER RIBONUCLE ACID (MRNA) WITH REDUCED IMMUNOSTIMULATING PROPERTIES
|
|
WO2015123527A1
(en)
|
2014-02-14 |
2015-08-20 |
Bellicum Pharmaceuticals, Inc. |
Methods for activating t cells using an inducible chimeric polypeptide
|
|
US9610358B2
(en)
*
|
2014-04-17 |
2017-04-04 |
Marker Gene Technologies, Inc |
Targeted pharmacological chaperones
|
|
US12214038B2
(en)
*
|
2014-07-22 |
2025-02-04 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for cancer immunotherapy
|
|
SG11201700839SA
(en)
|
2014-08-04 |
2017-03-30 |
Oncotherapy Science Inc |
Cdca1-derived peptide and vaccine containing same
|
|
EP3848383A3
(en)
|
2014-08-04 |
2021-11-03 |
Oncotherapy Science, Inc. |
Urlc10-derived peptide and vaccine containing same
|
|
RU2019126629A
(ru)
|
2014-08-04 |
2019-10-08 |
Онкотерапи Сайенс, Инк. |
Пептид, полученный из koc1, и содержащая его вакцина
|
|
EP3189148A4
(en)
|
2014-09-02 |
2018-05-02 |
Bellicum Pharmaceuticals, Inc. |
Costimulation of chimeric antigen receptors by myd88 and cd40 polypeptides
|
|
KR102229421B1
(ko)
*
|
2014-09-17 |
2021-03-19 |
더 존스 홉킨스 유니버시티 |
항원-특이적 t 세포 식별, 농축, 및/또는 증식을 위한 시약 및 방법
|
|
JP7005346B2
(ja)
*
|
2014-10-27 |
2022-02-04 |
フレッド ハッチンソン キャンサー リサーチ センター |
養子細胞免疫療法の有効性を増強させるための組成物および方法
|
|
EP3215522B1
(en)
|
2014-11-03 |
2021-12-01 |
Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum |
T cell receptors directed against bob1 and uses thereof
|
|
JP2018090491A
(ja)
*
|
2015-04-01 |
2018-06-14 |
株式会社細胞治療技術研究所 |
癌ワクチンの製造方法、及び癌ワクチン
|
|
US11090332B2
(en)
*
|
2015-05-21 |
2021-08-17 |
Regen BioPharma, Inc. |
Antigen specific mRNA cellular cancer vaccines
|
|
JP6666094B2
(ja)
*
|
2015-09-15 |
2020-03-13 |
株式会社東芝 |
吸着支持装置、および物品把持装置
|
|
AU2016335731B2
(en)
|
2015-10-08 |
2021-05-06 |
Oncotherapy Science, Inc. |
FOXM1-derived peptide, and vaccine including same
|
|
EP3410849B1
(en)
|
2016-02-05 |
2023-07-05 |
Institut Pasteur |
Use of inhibitors of adam12 as adjuvants in tumor therapies
|
|
US11723962B2
(en)
|
2016-05-04 |
2023-08-15 |
Fred Hutchinson Cancer Center |
Cell-based neoantigen vaccines and uses thereof
|
|
CN109414023A
(zh)
*
|
2016-06-29 |
2019-03-01 |
杜克大学 |
用嵌合脊髓灰质炎病毒激活抗原呈递细胞的组合物和方法
|
|
US20210069310A1
(en)
*
|
2018-01-05 |
2021-03-11 |
Rolf Jonas Andreas NILSSON |
Endogenous tumor-derived circular rna and proteins thereof for use as vaccine
|
|
TW202023581A
(zh)
|
2018-08-02 |
2020-07-01 |
日商腫瘤療法 科學股份有限公司 |
來自cdca1的胜肽及含有此的疫苗
|
|
US20250144143A1
(en)
*
|
2023-11-06 |
2025-05-08 |
Immunitybio, Inc. |
Virally Educated T cells
|