JP2000506133A5 - - Google Patents

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Publication number
JP2000506133A5
JP2000506133A5 JP1997530576A JP53057697A JP2000506133A5 JP 2000506133 A5 JP2000506133 A5 JP 2000506133A5 JP 1997530576 A JP1997530576 A JP 1997530576A JP 53057697 A JP53057697 A JP 53057697A JP 2000506133 A5 JP2000506133 A5 JP 2000506133A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1997530576A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000506133A (ja
Filing date
Publication date
Priority claimed from IT96MI000352A external-priority patent/IT1282686B1/it
Application filed filed Critical
Publication of JP2000506133A publication Critical patent/JP2000506133A/ja
Publication of JP2000506133A5 publication Critical patent/JP2000506133A5/ja
Pending legal-status Critical Current

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JP9530576A 1996-02-26 1997-02-24 薬剤由来の毒性を減少させることができる酸化窒素供与体 Pending JP2000506133A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96A000352 1996-02-26
IT96MI000352A IT1282686B1 (it) 1996-02-26 1996-02-26 Composti in grado di ridurre la tossicita' da farmaci
PCT/EP1997/000873 WO1997031654A1 (en) 1996-02-26 1997-02-24 Nitric oxide donors capable of reducing toxicity from drugs

Publications (2)

Publication Number Publication Date
JP2000506133A JP2000506133A (ja) 2000-05-23
JP2000506133A5 true JP2000506133A5 (enExample) 2004-11-25

Family

ID=11373387

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9530576A Pending JP2000506133A (ja) 1996-02-26 1997-02-24 薬剤由来の毒性を減少させることができる酸化窒素供与体

Country Status (16)

Country Link
US (1) US7087588B2 (enExample)
EP (2) EP1221326A3 (enExample)
JP (1) JP2000506133A (enExample)
KR (1) KR19990087113A (enExample)
AT (1) ATE220920T1 (enExample)
AU (1) AU706591B2 (enExample)
BR (1) BR9707739A (enExample)
CA (1) CA2247848C (enExample)
DE (1) DE69714253T2 (enExample)
DK (1) DK0904110T3 (enExample)
ES (1) ES2180938T3 (enExample)
HU (1) HUP9900993A3 (enExample)
IT (1) IT1282686B1 (enExample)
PT (1) PT904110E (enExample)
RU (1) RU2192247C2 (enExample)
WO (1) WO1997031654A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043232A (en) * 1997-07-23 2000-03-28 Nitromed, Inc. Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
GB9801398D0 (en) 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
IT1298338B1 (it) * 1998-03-05 1999-12-20 Nicox Sa Composizioni farmaceutiche per l'ulcera
US6297260B1 (en) 1998-10-30 2001-10-02 Nitromed, Inc. Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
US6649629B2 (en) 1999-12-23 2003-11-18 Nitromed, Inc. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
US7018979B1 (en) 2000-01-26 2006-03-28 Cedars-Sinai Medical Center Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
EP1251840A2 (en) * 2000-01-26 2002-10-30 Cedars-Sinai Medical Center Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor
DE60122939T2 (de) 2000-12-21 2007-01-11 Nitromed, Inc., Bedford Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
US7211561B2 (en) 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
US7378438B2 (en) 2002-04-19 2008-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders
US7220749B2 (en) 2002-06-11 2007-05-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
US7211598B2 (en) 2002-06-28 2007-05-01 Nitromed, Inc. Oxime and/or hydrozone containing nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004004648A2 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
AU2003261281A1 (en) 2002-07-29 2004-02-16 Nicox S.A. Cyclooxygenase- 2 selective inhibitors, compositions and methods of use
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
AU2005206227A1 (en) * 2004-01-27 2005-08-04 Merck Frosst Company Combination therapy for treating cyclooxygenase-2 mediated diseases or conditions in patients at risk of thrombotic cardiovascular events
JP4729503B2 (ja) * 2004-06-10 2011-07-20 日本化薬株式会社 抗癌剤の奏効率増強剤
JP2007325501A (ja) * 2004-08-25 2007-12-20 Tottori Univ 非ステロイド性抗炎症薬による動物の消化管副作用の予防・治療方法
AU2006249323B2 (en) 2005-05-27 2012-08-30 The University Of North Carolina At Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
US20100240745A1 (en) * 2009-03-20 2010-09-23 Nicox S.A. Method of treatment of inflammation in hypertensive patients
CA3062005C (en) 2009-08-21 2022-02-15 Novan, Inc. Topical gels comprising nitric oxide-releasing polysiloxane macromolecules and uses thereof
US9919072B2 (en) 2009-08-21 2018-03-20 Novan, Inc. Wound dressings, methods of using the same and methods of forming the same
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
JO3350B1 (ar) 2011-03-07 2019-03-13 Merck Sharp & Dohme مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات
RU2539630C1 (ru) * 2013-07-09 2015-01-20 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ профилактики ишемии сетчатки в эксперименте

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
WO1995009831A1 (en) 1993-10-06 1995-04-13 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
JP4043046B2 (ja) 1994-05-10 2008-02-06 ニコックス エス エイ 消炎、鎮痛および抗血栓活性を有するニトロ化合物およびそれらの組成物
US5597809A (en) * 1994-06-23 1997-01-28 Massachusetts Eye & Ear Infirmary Treatment of optic neuritis
US5703073A (en) 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5620416A (en) 1995-06-07 1997-04-15 North Carolina State University Methods of using topical agents with systemically administered active agents

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