JP2000506133A5 - - Google Patents
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- Publication number
- JP2000506133A5 JP2000506133A5 JP1997530576A JP53057697A JP2000506133A5 JP 2000506133 A5 JP2000506133 A5 JP 2000506133A5 JP 1997530576 A JP1997530576 A JP 1997530576A JP 53057697 A JP53057697 A JP 53057697A JP 2000506133 A5 JP2000506133 A5 JP 2000506133A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Description
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96A000352 | 1996-02-26 | ||
IT96MI000352A IT1282686B1 (it) | 1996-02-26 | 1996-02-26 | Composti in grado di ridurre la tossicita' da farmaci |
PCT/EP1997/000873 WO1997031654A1 (en) | 1996-02-26 | 1997-02-24 | Nitric oxide donors capable of reducing toxicity from drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2000506133A JP2000506133A (ja) | 2000-05-23 |
JP2000506133A5 true JP2000506133A5 (ja) | 2004-11-25 |
Family
ID=11373387
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9530576A Pending JP2000506133A (ja) | 1996-02-26 | 1997-02-24 | 薬剤由来の毒性を減少させることができる酸化窒素供与体 |
Country Status (16)
Country | Link |
---|---|
US (1) | US7087588B2 (ja) |
EP (2) | EP1221326A3 (ja) |
JP (1) | JP2000506133A (ja) |
KR (1) | KR19990087113A (ja) |
AT (1) | ATE220920T1 (ja) |
AU (1) | AU706591B2 (ja) |
BR (1) | BR9707739A (ja) |
CA (1) | CA2247848C (ja) |
DE (1) | DE69714253T2 (ja) |
DK (1) | DK0904110T3 (ja) |
ES (1) | ES2180938T3 (ja) |
HU (1) | HUP9900993A3 (ja) |
IT (1) | IT1282686B1 (ja) |
PT (1) | PT904110E (ja) |
RU (1) | RU2192247C2 (ja) |
WO (1) | WO1997031654A1 (ja) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5703073A (en) * | 1995-04-19 | 1997-12-30 | Nitromed, Inc. | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs |
US6043232A (en) * | 1997-07-23 | 2000-03-28 | Nitromed, Inc. | Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs |
GB9801398D0 (en) | 1998-01-22 | 1998-03-18 | Anggard Erik E | Chemical compounds |
IT1298338B1 (it) * | 1998-03-05 | 1999-12-20 | Nicox Sa | Composizioni farmaceutiche per l'ulcera |
CA2348741C (en) | 1998-10-30 | 2010-04-20 | Nitromed Inc. | Nitrosasted and nitrosylated nonsteroidal antiinflammatory compounds, comositions and methods of use |
TWI243672B (en) * | 1999-06-01 | 2005-11-21 | Astrazeneca Ab | New use of compounds as antibacterial agents |
US6436990B1 (en) | 1999-10-27 | 2002-08-20 | Nobex Corporation | 6-methoxy-2-naphthylacetic acid prodrugs |
US6552078B2 (en) | 1999-10-27 | 2003-04-22 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
TWI262791B (en) | 1999-10-27 | 2006-10-01 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
CA2393724A1 (en) | 1999-12-23 | 2001-06-28 | Nitromed, Inc. | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
EP1251840A2 (en) * | 2000-01-26 | 2002-10-30 | Cedars-Sinai Medical Center | Method for using potassium channel activation for delivering a medicant to an abnormal brain region and/or a malignant tumor |
US7018979B1 (en) | 2000-01-26 | 2006-03-28 | Cedars-Sinai Medical Center | Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor |
DE60122939T2 (de) | 2000-12-21 | 2007-01-11 | Nitromed, Inc., Bedford | Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren |
EP1219306A1 (en) * | 2000-12-29 | 2002-07-03 | Nicox S.A. | Compositions comprising cyclodextrins and NO- releasing drugs |
US7211561B2 (en) | 2001-10-12 | 2007-05-01 | Cedars-Sinai Medical Center | Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa) |
AU2003226603A1 (en) | 2002-04-19 | 2003-11-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders |
AU2003248642A1 (en) | 2002-06-11 | 2003-12-22 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
CA2492066A1 (en) | 2002-06-28 | 2004-01-08 | Nitromed, Inc. | Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
CA2491127A1 (en) | 2002-07-03 | 2004-01-15 | Nitromed, Inc. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
CA2493156A1 (en) | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
SE0300971D0 (sv) * | 2003-04-03 | 2003-04-03 | Aga Ab | Nitric oxide in treatment of inflammation |
WO2005070868A1 (en) * | 2004-01-27 | 2005-08-04 | Merck Frosst Company | Combination therapy for treating cyclooxygenase-2 mediated diseases or conditions in patients at risk of thrombotic cardiovascular events |
KR20070045187A (ko) * | 2004-06-10 | 2007-05-02 | 고쿠리츠다이가쿠호진 도호쿠다이가쿠 | 항암제의 효과 증강제 |
JP2007325501A (ja) * | 2004-08-25 | 2007-12-20 | Tottori Univ | 非ステロイド性抗炎症薬による動物の消化管副作用の予防・治療方法 |
EP3556401A1 (en) | 2005-05-27 | 2019-10-23 | The University of North Carolina at Chapel Hill | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications |
US20100240745A1 (en) * | 2009-03-20 | 2010-09-23 | Nicox S.A. | Method of treatment of inflammation in hypertensive patients |
WO2011022652A1 (en) | 2009-08-21 | 2011-02-24 | Novan, Inc. | Topical gels |
US9919072B2 (en) | 2009-08-21 | 2018-03-20 | Novan, Inc. | Wound dressings, methods of using the same and methods of forming the same |
US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
EP2681286B1 (en) | 2011-02-28 | 2018-08-15 | Novan, Inc. | Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same |
JO3350B1 (ar) | 2011-03-07 | 2019-03-13 | Merck Sharp & Dohme | مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات |
RU2539630C1 (ru) * | 2013-07-09 | 2015-01-20 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ профилактики ишемии сетчатки в эксперименте |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5570683A (en) | 1990-12-05 | 1996-11-05 | The General Hospital Corporation | Methods and devices for treating pulmonary vasoconstriction and asthma |
IT1256345B (it) | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
IT1256450B (it) | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
AU678063B2 (en) | 1993-10-06 | 1997-05-15 | Nicox S.A. | Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation |
DK0759899T3 (da) | 1994-05-10 | 1999-12-20 | Nicox Sa | Nitroforbindelser og sammensætninger deraf med antiinflammatoriske, analgetiske og antitrombotiske aktiviteter |
US5597809A (en) * | 1994-06-23 | 1997-01-28 | Massachusetts Eye & Ear Infirmary | Treatment of optic neuritis |
US5703073A (en) | 1995-04-19 | 1997-12-30 | Nitromed, Inc. | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs |
US5620416A (en) | 1995-06-07 | 1997-04-15 | North Carolina State University | Methods of using topical agents with systemically administered active agents |
-
1996
- 1996-02-26 IT IT96MI000352A patent/IT1282686B1/it active IP Right Grant
-
1997
- 1997-02-24 HU HU9900993A patent/HUP9900993A3/hu unknown
- 1997-02-24 AU AU20924/97A patent/AU706591B2/en not_active Ceased
- 1997-02-24 AT AT97906115T patent/ATE220920T1/de not_active IP Right Cessation
- 1997-02-24 EP EP02008079A patent/EP1221326A3/en not_active Withdrawn
- 1997-02-24 CA CA002247848A patent/CA2247848C/en not_active Expired - Fee Related
- 1997-02-24 DK DK97906115T patent/DK0904110T3/da active
- 1997-02-24 BR BR9707739A patent/BR9707739A/pt not_active Application Discontinuation
- 1997-02-24 JP JP9530576A patent/JP2000506133A/ja active Pending
- 1997-02-24 RU RU98117618/14A patent/RU2192247C2/ru not_active IP Right Cessation
- 1997-02-24 KR KR1019980706501A patent/KR19990087113A/ko not_active Application Discontinuation
- 1997-02-24 EP EP97906115A patent/EP0904110B1/en not_active Revoked
- 1997-02-24 WO PCT/EP1997/000873 patent/WO1997031654A1/en not_active Application Discontinuation
- 1997-02-24 ES ES97906115T patent/ES2180938T3/es not_active Expired - Lifetime
- 1997-02-24 DE DE69714253T patent/DE69714253T2/de not_active Revoked
- 1997-02-24 PT PT97906115T patent/PT904110E/pt unknown
-
2004
- 2004-07-07 US US10/885,121 patent/US7087588B2/en not_active Expired - Fee Related