JP2000506057A - 分配装置 - Google Patents

分配装置

Info

Publication number
JP2000506057A
JP2000506057A JP9530340A JP53034097A JP2000506057A JP 2000506057 A JP2000506057 A JP 2000506057A JP 9530340 A JP9530340 A JP 9530340A JP 53034097 A JP53034097 A JP 53034097A JP 2000506057 A JP2000506057 A JP 2000506057A
Authority
JP
Japan
Prior art keywords
detector
beads
container
tube
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9530340A
Other languages
English (en)
Japanese (ja)
Inventor
エル.カーク グレゴリー
ジェイ ブルゼジンスキー,ジューニア ジョセフ
チェルスキー ダニエル
ジー.ニコルズ サリーン
ティー.シー.ラマラージュ
Original Assignee
ファーマコピア,インク.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ファーマコピア,インク. filed Critical ファーマコピア,インク.
Publication of JP2000506057A publication Critical patent/JP2000506057A/ja
Pending legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0268Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00351Means for dispensing and evacuation of reagents
    • B01J2219/00364Pipettes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00457Dispensing or evacuation of the solid phase support
    • B01J2219/00459Beads
    • B01J2219/00468Beads by manipulation of individual beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00479Means for mixing reactants or products in the reaction vessels
    • B01J2219/00484Means for mixing reactants or products in the reaction vessels by shaking, vibrating or oscillating of the reaction vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00527Sheets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/282Producing thin layers of samples on a substrate, e.g. smearing, spinning-on with mapping; Identification of areas; Spatial correlated pattern

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Paper (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP9530340A 1996-02-26 1997-02-24 分配装置 Pending JP2000506057A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/606,573 US5649576A (en) 1996-02-26 1996-02-26 Partitioning device
US08/606,573 1996-02-26
PCT/US1997/002735 WO1997030897A1 (en) 1996-02-26 1997-02-24 Partitioning device

Publications (1)

Publication Number Publication Date
JP2000506057A true JP2000506057A (ja) 2000-05-23

Family

ID=24428518

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9530340A Pending JP2000506057A (ja) 1996-02-26 1997-02-24 分配装置

Country Status (6)

Country Link
US (1) US5649576A (cg-RX-API-DMAC7.html)
EP (1) EP0956238A1 (cg-RX-API-DMAC7.html)
JP (1) JP2000506057A (cg-RX-API-DMAC7.html)
AU (1) AU711029B2 (cg-RX-API-DMAC7.html)
CA (1) CA2238982A1 (cg-RX-API-DMAC7.html)
WO (1) WO1997030897A1 (cg-RX-API-DMAC7.html)

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KR100224655B1 (ko) * 1995-11-23 2000-02-01 윤종용 현상액 분사 점검시스템 및 이를 이용한 현상액 측정방법
EP0946278A1 (en) 1996-10-21 1999-10-06 Smithkline Beecham Plc Apparatus and method for distributing beads
JP2001527642A (ja) * 1997-01-17 2001-12-25 スミスクライン・ビーチャム・コーポレイション ビーズを配列するための装置および方法
GB9726482D0 (en) * 1997-12-15 1998-02-11 Kalibrant Limited Method and apparatus for chemical synthesis
US6884626B1 (en) 1998-04-27 2005-04-26 Corning Incorporated Redrawn capillary imaging reservoir
US6350618B1 (en) 1998-04-27 2002-02-26 Corning Incorporated Redrawn capillary imaging reservoir
DE69835342T2 (de) * 1998-04-27 2007-08-23 Corning Inc. Verfahren zur Ablage von biologischen Proben mit Hilfe eines nachgezogenen Kapillarspeichers
WO1999058476A2 (en) * 1998-05-08 1999-11-18 Chiron Corporation Method and device for nonsynthetic deconvolution
JP2002514832A (ja) * 1998-05-13 2002-05-21 スペクトラ システムズ コーポレーション マイクロレーザ光線発生ビーズと構造体及びその方法
EP2360271A1 (en) 1998-06-24 2011-08-24 Illumina, Inc. Decoding of array sensors with microspheres
US6762061B1 (en) 1998-07-03 2004-07-13 Corning Incorporated Redrawn capillary imaging reservoir
US7510841B2 (en) * 1998-12-28 2009-03-31 Illumina, Inc. Methods of making and using composite arrays for the detection of a plurality of target analytes
US6429027B1 (en) 1998-12-28 2002-08-06 Illumina, Inc. Composite arrays utilizing microspheres
US6151973A (en) * 1999-01-29 2000-11-28 Glaxo Wellcome Inc. Bead picking apparatus and method
US6432719B1 (en) * 1999-02-16 2002-08-13 Pe Corporation (Ny) Matrix storage and dispensing system
ATE341003T1 (de) 1999-02-16 2006-10-15 Applera Corp Vorrichtung zur handhabung von kügelchen
US7101510B2 (en) 1999-02-16 2006-09-05 Applera Corporation Matrix storage and dispensing system
IL148677A0 (en) * 1999-09-14 2002-09-12 Pharmacopeia Inc Article comprising a multi-channel dispensing head
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US6770441B2 (en) * 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
DE10236241B4 (de) * 2002-08-07 2005-04-21 Bavarian Nordic A/S Abfüllvorrichtung für Kapseln, insbesondere Arzneimittelkapseln
CA2513985C (en) 2003-01-21 2012-05-29 Illumina Inc. Chemical reaction monitor
US20060246576A1 (en) 2005-04-06 2006-11-02 Affymetrix, Inc. Fluidic system and method for processing biological microarrays in personal instrumentation
US20070258862A1 (en) * 2006-05-02 2007-11-08 Applera Corporation Variable volume dispenser and method
US7625115B2 (en) * 2006-06-23 2009-12-01 Exxonmobil Research And Engineering Company Method of blending lubricants using positive displacement liquid-handling equipment
US9523701B2 (en) 2009-07-29 2016-12-20 Dynex Technologies, Inc. Sample plate systems and methods
GB0913258D0 (en) 2009-07-29 2009-09-02 Dynex Technologies Inc Reagent dispenser
EP2894459A4 (en) * 2012-09-06 2016-04-27 Furukawa Electric Co Ltd APPARATUS FOR IDENTIFICATION AND OUTPUT OF SAMPLES AND METHOD FOR IDENTIFYING AND SUBMITTING SAMPLES
EP3376182A1 (en) * 2017-03-14 2018-09-19 CSEM Centre Suisse D'electronique Et De Microtechnique SA Fluid dispensing system and method
EP4089401B1 (de) * 2021-05-10 2024-11-06 Siemens Aktiengesellschaft Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz
US11820140B2 (en) 2022-03-21 2023-11-21 Funai Electric Co., Ltd Dispense modes for multi-mode capable device

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
BE793185A (fr) * 1971-12-23 1973-04-16 Atomic Energy Commission Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques
US4009435A (en) * 1973-10-19 1977-02-22 Coulter Electronics, Inc. Apparatus for preservation and identification of particles analyzed by flow-through apparatus
US4173415A (en) * 1976-08-20 1979-11-06 Science Spectrum, Inc. Apparatus and process for rapidly characterizing and differentiating large organic cells
US4184766A (en) * 1976-10-28 1980-01-22 Coulter Electronics, Inc. Method and apparatus for correlating measurements of tandem sensing zones
US4318480A (en) * 1979-08-20 1982-03-09 Ortho Diagnostics, Inc. Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device
US4606631A (en) * 1983-05-12 1986-08-19 Kabushiki Kaisha Toshiba Particle counter
US4538733A (en) * 1983-10-14 1985-09-03 Becton, Dickinson And Company Particle sorter with neutralized collection wells and method of using same
FR2571135B1 (fr) * 1984-10-02 1987-02-06 Moet & Chandon Procede et appareil de transfert et/ou de dosage de particules fragiles, a cadence elevee, en vue, par exemple, de l'insertion dans un recipient
US4680977A (en) * 1985-03-06 1987-07-21 Ivac Corporation Optical flow sensor
US5108926A (en) * 1987-09-08 1992-04-28 Board Of Regents, The University Of Texas System Apparatus for the precise positioning of cells
JPH03140840A (ja) * 1989-10-26 1991-06-14 Hitachi Ltd 流動細胞分析装置
JP2815435B2 (ja) * 1989-12-22 1998-10-27 株式会社日立製作所 粒子解析装置及び血球カウンタ
US5286452A (en) * 1991-05-20 1994-02-15 Sienna Biotech, Inc. Simultaneous multiple assays
EP0773227A1 (en) * 1991-09-18 1997-05-14 Affymax Technologies N.V. Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides
JPH08506175A (ja) * 1992-10-01 1996-07-02 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク タグでコードされる複合体の組合せ化学ライブラリー
US5483469A (en) * 1993-08-02 1996-01-09 The Regents Of The University Of California Multiple sort flow cytometer

Also Published As

Publication number Publication date
WO1997030897A1 (en) 1997-08-28
CA2238982A1 (en) 1997-08-28
AU2134197A (en) 1997-09-10
EP0956238A4 (cg-RX-API-DMAC7.html) 1999-11-17
EP0956238A1 (en) 1999-11-17
US5649576A (en) 1997-07-22
AU711029B2 (en) 1999-10-07

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