JP2000319152A - Dentifrice composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain the subject composition capable of readily sensing the finish of brushing in a touch feeling and a visual feeling by including copper sulfate as particles at a specific content. SOLUTION: This composition contains copper sulfate as particles in an amount of 1-30 wt.%, preferably 10-20 wt.% of the total composition. Preferably, an average particle diameter of the copper sulfate particles is 2-100 μm, especially 20-30 μm. The composition can be prepared as a kneaded dentifrice, etc., and used, and a usually used suitable component can be mixed with an other component, then a polisher (e.g. calcium hydrogenphosphate anhydride), a caking agent (e.g. carrageenan), a consistent agent, a surfactant, a sweetener (e.g. saccharin sodium), a perfume (e.g. menthol), preservatives, various active components, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dentifrice composition which can provide a tactile / visual sense of completion of brushing by blending copper sulfate as particles.

[0002]

2. Description of the Related Art
When brushing, there is no indication that the number of times of brushing necessary to thoroughly clean the teeth and how long the brushing should be sufficient, and usually depends on the habit and feeling of each person brushing. is there.

[0003] For this purpose, conventionally, calcium chloride and tripotassium phosphate are blended into a dentifrice composition, and the foaming caused by the foaming agent in the dentifrice composition is eliminated by brushing a predetermined number of times or for a predetermined time. An indicator dentifrice for detecting the end of brushing has been proposed (Japanese Patent Application Laid-Open No. 49-62652). However, this type of dentifrice contains a large amount of calcium chloride and tripotassium phosphate used as antifoaming agents. Has problems to formulate.

[0004] Further, by mixing microparticles obtained by microencapsulating a discoloring component in toothpaste and brushing it for a certain number of times or for a certain period of time, the film of the microcapsules is broken to discolor the toothpaste. A discolored dentifrice for sensing the end of the dentifrice has also been proposed (Japanese Patent Application Laid-Open No. 49-1737). However, this type of dentifrice has a problem that the discoloration in an aqueous system is unclear and its effect is not sufficiently exhibited. there were.

[0005] Accordingly, there has been a demand for the development of a dentifrice composition that can easily and visually sense the end of brushing.

[0006]

Means for Solving the Problems and Embodiments of the Invention The present inventors have conducted intensive studies in order to meet the above-mentioned demand, and as a result, by mixing copper sulfate as particles, a dentifrice composition capable of detecting the end of brushing. The present inventors have found that a product can be obtained, and have accomplished the present invention.

[0007] Inorganic salts such as sodium bicarbonate and sodium sulfate can be mentioned as substances which can be recognized in the dentifrice composition to be able to recognize the disintegration of particles during brushing. Hard to recognize. On the other hand, examples of colored inorganic salts include potassium potassium sulfate (ruby red) and chromium rubidium sulfate (purple). However, it is difficult to ensure stability of any inorganic salt except copper sulfate in the dentifrice composition.

Further, it is known that copper compounds such as copper gluconate and copper citrate have an antibacterial effect, an effect of removing bad breath and an effect of inhibiting plaque formation, and various oral compositions containing the copper compound have been proposed. (Japanese Patent Application Laid-Open No. 56-169519).
Nos. 56-169620 and 61-143317). However, the use of copper sulfate as particles in a dentifrice composition for use as a time indicator is related to new findings of the present inventors.

Hereinafter, the present invention will be described in more detail.
As described above, the dentifrice composition according to the present invention is a dentifrice composition containing copper sulfate as particles. In this case, the average particle size of the copper sulfate particles is preferably 2 μm or more, particularly preferably 20 μm or more, and 100 μm or less, particularly 30 μm or less.
The following is preferred. If the particle size is too small, it is difficult to detect the end of brushing, and if the particle size is too large, the feeling of use may deteriorate.

The compounding amount of the copper sulfate particles is from 1 to the total amount of the composition.
It is 30% by weight, preferably 10 to 20% by weight. If the amount of copper sulfate particles in the composition is too small, the end of the brushing cannot be sensed, and if it is too large, the dentifrice composition undergoes discoloration and the quality is reduced.

The dentifrice composition according to the present invention can be prepared and used as a toothpaste or the like, and can contain, as other components, appropriate components usually used, such as abrasives, binders, Agents, surfactants, sweeteners, flavors, preservatives, various active ingredients, and the like can be added.

For example, abrasives include calcium hydrogen phosphate / anhydride, calcium hydrogen phosphate / dihydrate,
Tribasic calcium phosphate, calcium carbonate, calcium pyrophosphate, aluminum hydroxide, silicic acid anhydride, aluminum silicate, insoluble sodium metaphosphate, tribasic magnesium phosphate, magnesium carbonate, calcium sulfate, bentonite, zirconium silicate, polymethyl methacrylate, One or more kinds of other synthetic resins and the like can be blended.

Examples of the binder include carrageenan, cellulose derivatives such as sodium carboxymethylcellulose, methylcellulose and hydroxyethylcellulose; alginic acid derivatives such as sodium alginate and propylene glycol alginate; gums such as xanthan gum, gellan gum, tragacanth gum, and karaya gum; One or more kinds of synthetic binders such as polyvinyl alcohol, sodium polyacrylate, and carboxyvinyl polymer, and inorganic binders such as silica gel, veegum, and laponite may be blended.

As humectants, glycerin, sorbitol, propylene glycol, polyethylene glycol,
One or more polyhydric alcohols such as xylitol, maltitol and lactitol may be blended.

As the surfactant, an anionic surfactant, a nonionic surfactant and an amphoteric surfactant are used.

Examples of the anionic surfactant include sodium alkyl sulfates such as sodium lauryl sulfate and sodium myristyl sulfate, and sodium N-lauroyl sarcosinate and sodium N-myristoyl sarcosinate.
N-acyl glutamates such as sodium acyl sarcosinate, sodium dodecylbenzenesulfonate, sodium hydrogenated coconut fatty acid monoglyceride monosulfate, sodium lauryl sulfoacetate, sodium N-palmitoyl glutamate, sodium N-methyl-N-acyl taurate, N -Methyl-N-acylalanine sodium, sodium α-olefin sulfonate and the like are used.

Examples of the nonionic surfactant include sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester and lactose fatty acid ester, sugar alcohol fatty acid esters such as maltitol fatty acid ester and lactitol fatty acid ester, and polyoxyethylene sorbitan. Monolaurate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, fatty acids such as lauric acid mono- or diethanolamide, myristic acid mono- or diethanolamide Mono or diethanolamide, sorbitan fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene copolymer, poly Alkoxy polyoxypropylene fatty acid ester or the like is used.

Examples of the amphoteric surfactant include betaine-based ones.

Examples of the fragrance component include menthol, anethole, carvone, eugenol, limonene, n-decyl alcohol, citronellol, α-terpineol, cineol, linalool, ethyl linalool, crocodile, thymol, peppermint oil, spearmint oil, wintergreen oil, Flavors such as clove oil and eucalyptus oil may be used alone or in combination.

As sweeteners, sodium saccharin,
Sweetening agents such as stevioside, dipotassium glycyrrhizinate, perillartin, thaumatin and the like can be added.

The active ingredients include fluorides such as sodium fluoride and sodium monofluorophosphate, enzymes such as dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme, tranexamic acid, epsilon aminocaproic acid, dipotassium glycyrrhizinate. , Glycyrrhetinic acid, bisabolol, chlorophyll, sodium chloride, water-soluble inorganic phosphate compound, triclosan, cetylpyridinium chloride, benzalkonium chloride,
One or more active ingredients such as benzethonium chloride may be blended.

The above components can be used in the usual amounts, and a dentifrice composition such as toothpaste can be produced according to a conventional method.

[0023]

According to the dentifrice composition of the present invention, the completion of brushing can be sensed tactilely and visually by adding copper sulfate as particles, and is of high commercial value.

[0024]

EXAMPLES The present invention will be described below in detail with reference to examples, but the present invention is not limited to the following examples. In addition, all% in each example are weight%. Also,
Copper sulfate having an average particle size of 25 μm was prepared.

[Examples 1 to 5, Comparative examples 1 to 5] Toothpaste compositions having the formulations shown in Table 1 were prepared and evaluated for the feel, perception and discoloration according to the following methods. The results are shown in Tables 1 to 3.

[Tactile sensation / recognition evaluation method] 1 to 2 g of toothpaste was placed on a brush to brush the teeth for a predetermined period of time.
The results are shown in Tables 2 and 3. In addition, the panel was 5 persons, and the result was shown by the average score of 5 persons. Tactile sensation 0 point: The particles (copper sulfate) do not collapse at all, and the feeling of the particles is the same as at the start of brushing. 1 point: The particles are slightly collapsed, and the particles are felt to be slightly finer than at the start of brushing. 2 Point: Particles disintegrated and the feeling of the particles almost disappeared. 3 Points: Particles completely disintegrated and the feeling of the particles disappeared at all. Cognitive 0 point: Particles (copper sulfate) did not disintegrate at all, toothpaste discharge liquid Blue particles (copper sulfate) can be clearly seen inside 1 point: Particles are slightly disintegrated, blue particles can be confirmed in toothpaste liquid 2 points: Particles are considerably disintegrated and blue particles are in toothpaste liquid Slight confirmation 3 points: The particles completely disintegrate, and blue particles cannot be confirmed in the toothpaste discharge method. [Discoloration evaluation method] Fill the toothpaste composition into a container such as a tube and store at 50 ° C for 1 month. Was evaluated by sensory evaluation. Evaluation criteria ○: no discoloration ×: discoloration

[0027]

[Table 1]

[0028]

[Table 2]

[0029]

[Table 3]

From the above results, it is not possible to obtain a tactile sensation / cognition with 0.3% copper sulfate (Comparative Example 1). On the other hand, copper sulfate 50
%, Touch feeling and cognition can be obtained, but discoloration occurs (Comparative Example 2). In addition, silica 20%, calcium hydrogen phosphate
Tactile sensation and cognition cannot be obtained with 30% non-hydrate and 25% calcium carbonate (Comparative Examples 3, 4, and 5). On the other hand, in the toothpaste compositions of the examples, after 2 minutes from the start of brushing, the collapse of the copper sulfate particles was recognized in terms of tactile sensation and cognition, and the end of brushing was clearly sensed. From this, it was confirmed that copper sulfate can correctly control the brushing time.

Example 6 Toothpaste Copper sulfate particles 10% Aluminum hydroxide 40 Propylene glycol 3 Sorbite (70%) 20 Propylene glycol alginate 0.6 Sodium carboxymethyl cellulose 0.5 Sodium lauroyl sarcosine 0.3 Sodium lauryl sulfate 1 Sodium fluoride 0.21 Sodium saccharin 0.1 Fragrance 1.2 Purified water Balance 100%

Example 7 Toothpaste Copper sulfate particles 10% silica 50 propylene glycol 2 glycerin (85%) 20 sodium carboxymethylcellulose 0.8 carrageenan 0.2 sodium lauryl sulfate 1.5 ε-aminocaproic acid 0.05 hydrofluoric acid Sodium fluoride 0.21 Saccharin sodium 0.15 Fragrance 1 Purified water Balance 100%

Example 8 Toothpaste Copper sulfate particles 15% Aluminum hydroxide 40 Propylene glycol 3 Glycerin (85%) 30 Sodium carboxymethylcellulose 0.2 Xanthan gum 0.6 Sodium lauryl sulfate 1.2 Dipotassium glycyrrhizinate 0.05 Sodium fluoride 0.21 Sodium saccharin 0.15 Fragrance 1.2 Purified water Balance 100%

Example 9 Toothpaste Copper sulfate particles 20% Silica 40 Propylene glycol 3 Glycerin (85%) 15 Sodium carboxymethylcellulose 0.1 Xanthan gum 0.7 Sodium lauryl sulfate 1.8 ε-Aminocaproic acid 0.05 Mono Sodium fluorophosphate 0.76 Sodium saccharin 0.1 Perfume 0.9 Purified water Balance 100%

[Example 10] Toothpaste Copper sulfate particles 15% Calcium hydrogen phosphate dihydrate 55 Propylene glycol 3 Sorbitol (70%) 15 Sodium carboxymethyl cellulose 0.3 Xanthan gum 0.5 Sodium lauryl sulfate 1 Glycyrrhizic acid Dipotassium 0.05 Saccharin sodium 0.15 Fragrance 0.8 Purified water Balance 100%

Example 11 Toothpaste Copper sulfate particles 8% Calcium hydrogen phosphate dihydrate 45 Propylene glycol 2.5 Glycerin (85%) 25 Carrageenan 0.4 Xanthan gum 0.3 Lauroyl sarcosine sodium 0.1 Sodium lauryl sulfate 1.2 Tranexamic acid 0.05 Triclosan 0.05 Saccharin sodium 0.1 Fragrance 1.5 Purified water Balance 100%

Example 12 Toothpaste Copper Sulfate Particles 10% Calcium Carbonate 40 Propylene Glycol 3 Glycerin (85%) 20 Sodium Carboxymethyl Cellulose 0.4 Xanthan Gum 0.6 Sodium Lauryl Sulfate 1.5 Tranexamic Acid 0.05 Saccharin Sodium 0 1.1 Perfume 1.1 Purified water Balance 100%

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Claims (1)

[Claims] 1. The composition according to claim 1, wherein copper sulfate is used as particles.
A dentifrice composition characterized by containing 0% by weight.