JP2002104945A - Dentifrice composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dentifrice composition that has high effect of removing the fur from the furred tongue with good sense of use. SOLUTION: This fur-removing dentifrice composition includes hydrogen carbonate salt and condensed phosphate salt in which the amount of the hydrogen carbonate is characteristically <=1 mass % and the mass ratio of the hydrogen carbonate to the condensed phosphate is 1/10-1/2.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a dentifrice composition having an excellent effect on removing tongue coating.

[0002]

2. Description of the Related Art
It is known to incorporate sodium hydrogen carbonate (alkali metal bicarbonate) into oral compositions such as dentifrices and mouthwashes (JP-A-49-69849, JP-A-52-540).
38, JP-A-59-176206, JP-A-63-192712).

On the other hand, regarding the effect of removing tongue coating, condensed phosphate has an effect of removing tongue coating (Japanese Patent Laid-Open No. 10-182).
No. 387, Japanese Patent Application Laid-Open No. 10-182388) are known. As a means for physically removing tongue coating, a tongue brush and the like are known (Japanese Utility Model Laid-Open No. 6-283). Furthermore, a technique is known in which crystalline cellulose is blended in order to remove tongue coating, which is the main cause of physiological bad breath, and is effectively removed by brushing several times (JP-A-11-17175).
0, JP-A-11-171751).

However, since condensed phosphoric acid compounds alone cannot provide a sufficient effect, a combined use with alkyldiaminoethylglycine hydrochloride has been proposed (JP-A-11-209257). There were problems such as occurrence. Moreover, the method of removing tongue coating by brushing may damage the surface of the tongue when strongly polished.

[0005] Further, the applicant of the present invention has proposed that
Since it is effective for the chemical removal of tongue coating, compositions containing bicarbonate as an active ingredient for removing tongue coating were proposed (Japanese Patent Application Nos. 10-182385 and 11-108132).
No.), when a bicarbonate is blended, if the effect of removing the tongue coating is sufficiently imparted, the blending amount of the bicarbonate is increased, and the salty taste peculiar to the bicarbonate is strong, so that the usability may be deteriorated.

The present invention has been made in view of the above circumstances, and has as its object to provide a tongue coating removing dentifrice composition having a high tongue coating removing effect, a good taste, and a high feeling of use.

[0007]

Means for Solving the Problems and Embodiments of the Invention As a result of intensive studies to achieve the above object, the present inventor has found that a bicarbonate and a condensed phosphate are used in combination. By limiting the blending amount of the bicarbonate to 1% or less (percent by mass, the same applies hereinafter) and by setting the blending ratio of the bicarbonate and the condensed phosphate to 1/10 to 1/2 by mass ratio, Efficient removal of tongue coating and good taste,
It has been found that a dentifrice composition for removing tongue coating having a high feeling of use can be obtained.

In this case, sodium acrylate and xanthan gum are used in combination with the dentifrice composition containing the hydrogencarbonate and the condensed phosphate as a binder, and sodium alginate is further added as a low-temperature stabilizer. By blending 0.1 to 1%, a more favorable dentifrice composition in terms of liquid separation and spinnability can be obtained, and particularly, the stability when stored at low temperatures for a long period of time is improved. It has been found that a good appearance can be maintained.

Hereinafter, the present invention will be described in more detail.
The dentifrice composition for removing tongue coating according to the present invention is a combination of bicarbonate and condensed phosphate.

In this case, a water-soluble salt such as sodium hydrogen carbonate is used as the hydrogen carbonate. The amount is 1
%, Preferably 0.01 to 1%, more preferably 0.2 to 0.5%.

On the other hand, the condensed phosphate used in the present invention has the following general formula (1): M _{n + 2} P _n O _{3n + 1} (1) (where M represents Na or K, and n ≧ 2) And a linear polyphosphate represented by the following general formula (2) (MPO ₃ ) _m (2) (where M represents Na or K and m ≧ 3). These are cyclic polyphosphates, and one or more of them can be used in combination.

The chain length of the above-mentioned linear polyphosphate is not particularly limited as long as it is 2 or more.
Particularly preferred is 2 to 20, for example, sodium or potassium pyrophosphate having a polymerization degree of n = 2, sodium or potassium tripolyphosphate having n = 3,
Examples thereof include sodium tetrapolyphosphate and potassium tetrapolyphosphate with n = 4, and sodium metaphosphate and potassium metaphosphate having a high degree of polymerization.

On the other hand, the chain length of the cyclic polyphosphate is not particularly limited as long as it is 3 or more.
30, particularly preferably 3 to 20, for example, the degree of polymerization m
= 3 sodium trimetaphosphate and potassium trimetaphosphate, m = 4 sodium tetrametaphosphate and potassium tetrametaphosphate, and m = 6 sodium hexametaphosphate and potassium hexametaphosphate.

Among the above-mentioned condensed phosphates, sodium pyrophosphate and sodium tripolyphosphate are preferred.

The amount of the condensed phosphate is based on the mixing ratio with the above-mentioned hydrogen carbonate, that is, hydrogen carbonate / condensed phosphate (mass ratio) =
The ratio is 1/10 to 1/2, preferably 1/5 to 1/2, and more preferably 1/5 to 2/5. If the ratio is outside this range, the effect of removing tongue coating is reduced.

In the present invention, in addition to the above components, sodium polyacrylate, xanthan gum, and sodium alginate as a low-temperature stabilizer are preferably used in combination, whereby the composition is stable even after long-term storage, especially after low-temperature storage. A toothpaste that does not impair the appearance of the paste can be obtained.

The total amount of sodium polyacrylate and xanthan gum is 0.3 to 4%, especially 0.5 to 4%.
~ 2% is desirable. The compounding ratio is 4: 1 as a mass ratio.
１ ： 1: 5, particularly preferably 2: 1 to 1: 3. If the compounding ratio of sodium polyacrylate is higher than 4: 1, liquid separation may occur, and if the compounding ratio of xanthan gum is higher than 1: 5, the spinnability may increase and the usability may decrease.

On the other hand, the amount of sodium alginate to be compounded as a low-temperature stabilizer is 0.1 to 1%, particularly 0.2 to 1%.
A range of 0.7% is desirable. If the amount is less than 0.1%, the effect of stabilizing sodium alginate at low temperatures cannot be obtained, and
%, The feeling of use may be sticky or discoloration may occur after storage at high temperatures.

As far as the effects of the present invention are not hindered, one or two of organic binders such as sodium carboxymethylcellulose, hydroxyethylcellulose and carrageenan and inorganic binders such as silica gel, veegum and laponite are used as binders. Mixing more than one species is also acceptable.

The dentifrice composition according to the present invention can be prepared as toothpaste, lubricating toothpaste, liquid dentifrice, etc., and the form of toothpaste is particularly preferred. In this case, as other components, appropriate components commonly used can be blended.

For example, as the humectant, one or more polyhydric alcohols such as glycerin, sorbitol, propylene glycol, polyethylene glycol, xylitol, maltitol and lactitol can be blended.

Examples of the abrasive include silica abrasives such as precipitated silica, silica gel, aluminosilicate and zirconosilicate, dibasic calcium phosphate dihydrate and anhydride, calcium pyrophosphate, calcium carbonate, aluminum hydroxide, alumina , Magnesium carbonate, tribasic magnesium phosphate, insoluble sodium metaphosphate, insoluble potassium metaphosphate, titanium oxide, zeolite, aluminum silicate, zirconium silicate, and a synthetic resin-based abrasive.

As the surfactant, an anionic surfactant, a nonionic surfactant and an amphoteric surfactant are used. In this case, examples of the anionic surfactant include sodium alkyl sulfate such as sodium lauryl sulfate and sodium myristyl sulfate; sodium N-acyl sarcosinate such as sodium N-lauroyl sarcosinate; sodium N-myristoyl sarcosinate; and dodecylbenzene sulfone. Sodium acid, hydrogenated coconut fatty acid,
N-acyl glutamates such as sodium monoglyceride monosulfate, sodium lauryl sulfoacetate, sodium N-palmitoyl glutamate, sodium N-methyl-N-acyltaurine, sodium N-methyl-N-acylalanine, sodium α-olefin sulfonate, etc. Is used.

Examples of the nonionic surfactant include sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester and lactose fatty acid ester, sugar alcohol fatty acid esters such as maltitol fatty acid ester and lactitol fatty acid ester, and polyoxyethylene sorbitan. Monolaurate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, fatty acids such as lauric acid mono- or diethanolamide, myristic acid mono- or diethanolamide Mono or diethanolamide, sorbitan fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene copolymer, poly Alkoxy polyoxypropylene fatty acid ester or the like is used.

As the fragrance component, menthol, anethole, carvone, eugenol, limonene, n-decyl alcohol, citronellol, α-terpineol, cineol, linalool, ethyl linalool, crocodile, thymol, peppermint oil, spearmint oil, wintergreen oil, Flavors such as clove oil and eucalyptus oil can be used alone or in combination.

As the sweetener, saccharin sodium,
Sweetening agents such as stevioside, dipotassium glycyrrhizinate, perillartin, thaumatin and the like can be added.

The active ingredients include fluorides such as sodium fluoride and sodium monofluorophosphate, enzymes such as dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme, tranexamic acid, epsilon aminocaproic acid, dipotassium glycyrrhizinate. , Glycyrrhetinic acid, bisabolol, chlorophyll, sodium chloride, water-soluble inorganic phosphate compound, triclosan, cetylpyridinium chloride, benzalkonium chloride,
One or more active ingredients such as benzethonium chloride may be blended.

[0028]

EXAMPLES Hereinafter, the present invention will be described specifically with reference to Examples, Comparative Examples, and Experimental Examples, but the present invention is not limited to the following Examples. In the following examples,% indicates mass percentage.

Example 1 Toothpaste Sodium Bicarbonate 0.6% Sodium Tripolyphosphate 3 Fragrance 1 Propylene Glycol 3 85% Glycerin 30 Xanthan Gum 0.8 Carboxymethyl Cellulose Sodium 0.3 Abrasive Silica 15 Sodium Lauryl Sulfate 1.2 Saccharin sodium 0.1 Purified water Balance 100%

Example 2 Toothpaste Sodium Bicarbonate 0.6% Sodium Pyrophosphate 2 Perfume 1 Propylene Glycol 3 70% Sorbite 30 Carrageenan 0.4 Sodium Carboxymethyl Cellulose 0.2 Abrasive Silica 20 Sodium Lauryl Sulfate 1.8 Saccharin sodium 0.05 Purified water Balance 100%

Comparative Example 1 Liquid Dentifrice Sodium Bicarbonate 5% Fragrance 1 Propylene Glycol 3 85% Glycerin 25 Xanthan Gum 0.2 Sodium Polyacrylate 0.2 Abrasive Silica 10 Sodium Lauryl Sulfate 1.5 Saccharin Sodium 0.2 Purification Water balance 100%

Comparative Example 2 Mouthwash Glycerin 20% Ethyl Alcohol 15 Polyoxyethylene Hardened Castor Oil 2 Sodium Bicarbonate 1 Sodium Fluoride 0.1 Perfume 1 Purified Water Balance 100%

[Comparative Example 3] Toothpaste Potassium hydrogen carbonate 10% Fragrance 1 Propylene glycol 3 85% Glycerin 25 Xanthan gum 0.7 Sodium polyacrylate 0.7 Abrasive silica 20 Sodium lauryl sulfate 1.5 Saccharin sodium 0.2 Purification Water balance 100%

Comparative Example 4 Toothpaste Sodium hydrogencarbonate 1% Fragrance 1 Propylene glycol 2.5 70% Sorbite 25 Sodium carboxymethylcellulose 1.2 Aluminum hydroxide 18 Sodium lauryl sulfate 1.3 Saccharin sodium 0.15 Purified water Balance 100%

Comparative Example 5 Toothpaste Sodium Pyrophosphate 5% Fragrance 1 Polyethylene Glycol 2.5 70% Sorbit 20 Carrageenan 1.0 Xanthan Gum 0.2 Calcium Carbonate 25 Sodium Lauryl Sulfate 1.3 Sodium Saccharin 0.2 Purified Water Residue 100% in total

Comparative Example 6 Toothpaste Sodium Bicarbonate 3% Sodium Tripolyphosphate 6 Fragrance 1 Propylene Glycol 2.5 70% Sorbite 25 Sodium Carboxymethyl Cellulose 1.2 Calcium Hydrogen Phosphate 18 Sodium Lauryl Sulfate 1.3 Sodium Saccharin 0.0 15 purified water balance 100%

[Comparative Example 7] Toothpaste 5% sodium bicarbonate 5% sodium hexametaphosphate 5 Fragrance 1 Propylene glycol 2.5 85% Glycerin 25 Carrageenan 1.2 Silicic anhydride 18 Sodium lauryl sulfate 1.3 Saccharin sodium 0.15 Purified water 100% remaining

Comparative Example 8 Toothpaste Potassium hydrogen carbonate 0.5% Sodium trimetaphosphate 0.5 Perfume 0.8 Propylene glycol 3 85% Glycerin 25 Carboxymethylcellulose sodium 1.5 Calcium carbonate 20 Sodium lauryl sulfate 1.3 Saccharin sodium 0.1 purified water balance 100%

The tongue coating removal effect and the feeling of use of the compositions obtained in the above Examples and Comparative Examples were evaluated by the following methods. Table 1 shows the results. <Evaluation method of tongue moss removal effect> Fuzo preliminarily anaerobically cultured on cut hamster teak pouch (1 cm square)
Attach Nucleatum bacteria. Next, after washing the adhered bacteria (tongue coating) twice with water, 3 ml of a sample liquid obtained by diluting and dispersing the composition of the above-described formulation three times with purified water was added, and the mixture was added at 37 ° C. for 30 minutes. Operate with shaking. Next, the sample solution is discarded, and after washing three times with water, the amount of the remaining bacteria is measured. A similar experiment was performed using a sample to which no sample was added as a control, and the tongue coating removal rate was determined from the following equation based on the amount of attached bacteria (XO) at that time and the amount of attached bacteria (XS) using the sample solution. . Tongue coating removal rate (%) = [(XO-XS) / XO] × 100 <feel of use> ○: no salty ×: salty

[0040]

[Table 1]

[Experimental Example] Each toothpaste shown in Table 2 was prepared and filled in a laminate tube. The moldability and spinnability of the dentifrice discharged from the container immediately after production were evaluated by the following methods. After storing these at 40 ° C. and 0 ° C. for 3 months, ease of pushing out the dentifrice from the container, appearance, and liquid separation were evaluated based on the following evaluation criteria. Table 2 shows the results. Evaluation standard for spinnability The dentifrice was squeezed out from a laminate tube onto paper, and the degree of stringing (the degree of elongation of kneading) when the tube mouth was lifted right above was evaluated. ：: Little stringing (elongation less than 5 mm) △: Slight stringing (elongation 5 to 15 mm) ×: Stringing (elongation 15 mm or more) Extrusion ease evaluation criteria △: Smooth dentifrice △: Slightly hard but dentifrice can be dispensed. ×: Hard and difficult to disperse dentifrice (evaluation of color tone and uniformity) 〇: Uniform state without discoloration and no layer separation due to settling of abrasive, etc. △: Slight Unsatisfactory discoloration or layer separation has occurred. X: Remarkable discoloration or abrasion agent has separated and sedimented, resulting in layer separation. Liquid separation evaluation criteria. ○: No liquid seepage. Δ: Slight liquid seepage. ×: Comprehensive evaluation with many liquid seepages ◎: Samples with all items marked with ○ (particularly excellent samples) ○: Samples with 1 to 3 items out of all items, and samples with ○ in the rest △: All 4 to 6 of the items are marked with “△” and the rest are samples of ○: ×: 1 of all items Samples marked with x for items, or samples marked with △ for more than 7 items without x

[0042]

[Table 2]

[0043]

EFFECT OF THE INVENTION The dentifrice composition of the present invention has a high tongue coating removing effect and is excellent in use feeling.

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[Procedure amendment]

[Submission date] September 28, 2000 (2009.2)
8)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] 0008

[Correction method] Change

[Correction contents]

In this case, sodium acrylate and xanthan gum are used in combination with the dentifrice composition containing the hydrogencarbonate and the condensed phosphate as a binder, and sodium alginate is further added as a low-temperature stabilizer. It has been found that, by blending 0.1 to 1%, the stability, especially when stored for a long time at a low temperature, is improved, and a good appearance can be maintained.

[Procedure amendment 2]

[Document name to be amended] Statement

[Correction target item name] 0041

[Correction method] Change

[Correction contents]

[Experimental Example] Each toothpaste shown in Table 2 was prepared and filled in a laminate tube. These 4
After storage at 0 ° C. and 0 ° C. for 3 months, spinnability, ease of pushing out the dentifrice from the container, appearance, and liquid separation were evaluated based on the following evaluation criteria. Table 2 shows the results. Evaluation standard for spinnability The dentifrice was squeezed out from a laminate tube onto paper, and the degree of stringing (the degree of elongation of kneading) when the tube mouth was lifted right above was evaluated. ：: Little stringing (elongation less than 5 mm) △: Slight stringing (elongation 5 to 15 mm) ×: Stringing (elongation 15 mm or more) Extrusion ease evaluation criteria △: Smooth dentifrice △: Slightly hard but dentifrice can be dispensed. ×: Hard and difficult to disperse dentifrice (evaluation of color tone and uniformity) 〇: Uniform state without discoloration and no layer separation due to settling of abrasive, etc. △: Slight Unsatisfactory discoloration or layer separation has occurred. X: Remarkable discoloration or abrasion agent has separated and sedimented, resulting in layer separation. Liquid separation evaluation criteria. ○: No liquid seepage. Δ: Slight liquid seepage. ×: Comprehensive evaluation with many liquid seepages ◎: Samples with all items marked with ○ (particularly excellent samples) ○: Samples with 1 to 3 items out of all items, and samples with ○ in the rest △: All 4 to 6 of the items are marked with “△” and the rest are samples of ○: ×: 1 of all items Samples marked with x for items, or samples marked with △ for more than 7 items without x

 ──────────────────────────────────────────────────の Continuing on the front page (72) Takashi Yamamoto Inventor 1-chome, 3-7, Honjo, Sumida-ku, Tokyo F-term in Lion Corporation (reference) 4C083 AB172 AB281 AB282 AB311 AB312 AC122 AC132 AC782 AC862 AD091 AD092 AD272 AD301 AD351 AD352 CC41 DD22 DD23 EE01 EE03 EE06 EE07 EE34

Claims (3)

[Claims] Claims: 1. A composition comprising a bicarbonate and a condensed phosphate,
The bicarbonate compounding amount is 1% by mass or less, and the mixing ratio between the bicarbonate salt and the condensed phosphate is 1/10 to 1 as a mass ratio.
/ 2, a dentifrice composition for removing tongue coating. 2. The dentifrice composition according to claim 1, further comprising sodium polyacrylate, xanthan gum, and 0.1 to 1% by mass of sodium alginate as a low-temperature stabilizer. 3. The dentifrice composition according to claim 1, which is a toothpaste composition.