JPH1121219A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To improve the astringency of a composition for an oral cavity containing a compound having the astringency such as sodium pyrophosphate, potassium pyrophosphate, sodium polyphosphate, sodium bicarbonate, phytic acid or its salt, allantoin, chlorohydroxyaluminum or lactic acid, tartaric acid, succinic acid, citric acid, tannic acid or a salt thereof, etc. SOLUTION: This composition for an oral cavity is obtained by formulating one or more waxes selected from lanolin and its derivative, spermaceti, carnauba wax, candelilla wax and beeswax in the composition for the oral cavity containing a compound having the astringency.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to sodium pyrophosphate, potassium pyrophosphate, sodium polyphosphate, sodium bicarbonate, phytic acid or a salt thereof, allantoin, chlorohydroxyaluminum, or lactic acid, tartaric acid, succinic acid, citric acid, tannic acid Or one or more waxes selected from lanolin and its derivatives, spermaceti, carnauba wax, candelilla wax and beeswax in an oral composition containing an astringent compound such as a salt thereof. Accordingly, the present invention relates to an oral composition having improved astringency and improved feeling upon use.

[0002]

2. Description of the Related Art
It is known to compound compounds such as sodium pyrophosphate, potassium pyrophosphate, sodium polyphosphate, sodium bicarbonate, and aluminum lactate in oral compositions such as dentifrice,
An oral composition containing these compounds has astringency and impairs the feeling of use.

[0003] In particular, condensed phosphates such as pyrophosphates and polyphosphates have an effect of inhibiting the formation of tartar, and the amount is sufficient (usually about 0.1 to 10% by weight) to sufficiently exhibit the effect. When the oral composition containing (1) is used, the oral mucous membrane is stimulated and converges, thereby deteriorating the feeling of use.

[0004] Therefore, it is desired to improve the astringency of an oral composition containing such an astringent compound.

[0005]

Means for Solving the Problems and Embodiments of the Invention The present inventors have conducted intensive studies to meet the above-mentioned demand, and as a result, have found that an oral composition containing a compound having astringency is
By blending one or more waxes selected from lanolin and its derivatives, spermaceti, carnauba wax, candelilla wax and beeswax, astringency is improved, the feeling of use is improved, and the above object is achieved. It has been found that the present invention has been accomplished.

As for the improvement of astringency, improvement by a compound having an astringent property, such as an amino acid or a protein, has been proposed (JP-A-61-23768).
In addition, it has been proposed to mix wax or shellac in an oral composition for the purpose of imparting gloss to teeth (Japanese Patent Application Laid-Open No. 8-310929). Suppressing the astringency of the composition is a new finding by the present inventors.

Hereinafter, the present invention will be described in more detail.
The oral composition according to the present invention, as described above, contains a compound having an astringent property.Examples of the compound having an astringent property include sodium pyrophosphate, potassium pyrophosphate, sodium polyphosphate, sodium bicarbonate, Examples include phytic acid or a salt thereof, allantoin, chlorohydroxyaluminum, lactic acid, tartaric acid, succinic acid, citric acid, tannic acid, and salts thereof. In the present invention, one kind of these compounds may be contained, or two or more kinds thereof may be contained. In addition, these compounds
It is appropriately blended and used in various amounts depending on the purpose of each blending.
% (% By weight, the same applies hereinafter), particularly 0.01 to 5%.

In this case, the present invention provides a compound having the astringent property, in particular, represented by the following general formula (1) or (2): M _{n + 2} P _n O _{3n + 1} (1) (MPO ₃ ) _m (2) (Where M represents Na or K, m is 3 or more, and n is 2)
The above is an integer. ) Represented by a linear or cyclic condensed phosphate or phytate, lactic acid, aluminum lactate,
It is effective when baking soda is used.

The present invention relates to an oral composition containing such an astringent compound, wherein one or more waxes selected from lanolin and its derivatives, spermaceti, carnauba wax, candelilla wax and beeswax are added to the composition. By blending, the astringency can be improved and the feeling of use can be improved.

In this case, all of the above-mentioned waxes can be used, but lanolin and its derivatives are preferred.

[0011] The amount of the waxes is 0.1% of the whole composition.
The content is preferably 1 to 10%, particularly preferably 0.3 to 5%.
If the compounding amount is less than 0.1%, no effect is observed,
On the other hand, if it exceeds 10%, the taste of wax itself may have an adverse effect on taste.

The composition for the oral cavity according to the present invention can be prepared into a toothpaste, a lubricating toothpaste, a liquid toothpaste, a mouthwash, a mouth freshener, etc. In this case, other components are usually used. Appropriate components can be blended, and abrasives, binders, thickeners, surfactants, sweeteners, flavors, preservatives, various active ingredients, and the like can be blended.

For example, abrasives include dibasic calcium phosphate dihydrate and anhydride, monobasic calcium phosphate,
Tertiary calcium phosphate, calcium carbonate, calcium pyrophosphate, aluminum hydroxide, alumina, silicic acid, aluminum silicate, insoluble sodium metaphosphate, tertiary magnesium phosphate, magnesium carbonate, calcium sulfate, bentonite, zirconium silicate, polymethacrylic acid One or two of methyl, other synthetic resin, etc.
More than one species may be included.

Examples of the binder include carrageenan, sodium carboxymethylcellulose, cellulose derivatives such as methylcellulose and hydroxyethylcellulose, gums such as xanthan gum, tragacanth gum, karaya gum and gum arabic, polyvinyl alcohol, sodium polyacrylate, carboxyvinyl polymer, and the like. One or more kinds of synthetic binders such as polyvinylpyrrolidone, inorganic binders such as silica gel, aluminum silica gel, veegum, and laponite may be blended.

As the thickener, sorbitol, glycerin, ethylene glycol, propylene glycol,
One or more of 1,3-butylene glycol, polyethylene glycol, polypropylene glycol, xylitol, maltitol, lactitol and the like can be blended.

Further, fragrance components such as menthol, anethole, carvone, eugenol, limonene, n-decyl alcohol, citronellol, α-terpineol,
Citronellyl acetate, cineol, linalool, ethyl linalool, crocodile, thymol, spearmint oil, peppermint oil, lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, pimento oil, cinnamon oil, perilla oil, winter green oil, Flavors such as clove oil and eucalyptus oil may be used alone or in combination, and sweetness such as saccharin sodium, stevioside, neohesperidyl dihydrochalcone, glycyrrhizin, perillartin, thaumatin, asparatyl phenylalanine methyl ester, p-methoxycinnamic aldehyde, etc. And the like.

The active ingredient may be an enzyme such as dextranase, mutanase, lysozyme, amylase, protease, lytic enzyme or superoxide dismutase, or an alkali metal monofluorophosphate such as sodium monofluorophosphate or potassium monofluorophosphate. And sodium fluoride, fluorides such as stannous fluoride, tranexamic acid, epsilon aminocaproic acid,
Dihydrocholestanol, glycyrrhizic acids, glycyrrhetinic acid, bisabolol, isopropylmethylphenol, glycerophosphate, chlorophyll, sodium chloride, water-soluble inorganic phosphate compound, triclosan, cetylpyridinium chloride, benzalkonium chloride,
One or more active ingredients such as benzethonium chloride may be blended.

As the surfactant, anionic surfactants, nonionic surfactants and amphoteric surfactants are used.

Examples of the anionic surfactant include sodium alkyl sulfate such as sodium lauryl sulfate and sodium myristyl sulfate; sodium N-acyl sarcosinate such as sodium N-lauroyl sarcosinate; sodium N-myristoyl sarcosinate; and dodecylbenzene sulfone. Sodium acid, hydrogenated coconut fatty acid sodium monoglyceride monosulfate, sodium lauryl sulfoacetate, N-acylglutamate such as sodium N-palmitoylglutamate, sodium N-methyl-N-acyltaurine, sodium N-methyl-N-acylalanine, Sodium α-olefin sulfonate and the like are used.

Examples of the nonionic surfactant include sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester and lactose fatty acid ester, sugar alcohol fatty acid esters such as maltitol fatty acid ester and lactitol fatty acid ester, and polyoxyethylene sorbitan. Monolaurate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene hydrogenated castor oil, lauric acid mono- or diethanolamide, fatty acids such as myristic mono- or diethanolamide Diethanolamide, sorbitan fatty acid ester, polyoxyethylene higher alcohol ether, polyoxyethylene polyoxypropylene copolymer, polyoxyethylene Like polyoxypropylene fatty acid ester is used.

Examples of the zwitterionic surfactant include N-alkyldiaminoethylglycine such as N-lauryldiaminoethylglycine and N-myristyldiaminoethylglycine, N-alkyl-N-carboxymethylammonium betaine, and 2-alkyl-1-amine. Hydroxyethylimidazoline betaine sodium is used.

[0022]

According to the present invention, there is provided an oral composition containing an astringent compound, comprising one or more selected from lanolin and its derivatives, spermaceti, carnauba wax, candelilla wax and beeswax. By improving the astringency by blending the waxes, the feeling of use is improved and the commercial value is high.

[0023]

EXAMPLES The present invention will be described below in detail with reference to Examples and Comparative Examples, but the present invention is not limited to the following Examples. In addition, all% in each example are weight%.

Examples 1 to 9 and Comparative Examples 1 to 6 Tables 1 and 2
Was prepared, and its astringency was sensory evaluated by a specialized panel of 10 persons. The results are shown in Tables 1 and 2. The evaluation criteria are as follows. <Evaluation Criteria> ◎: No astringency No. of 10 panelists who did not converge: 10 No. of persons who converged: 0 ○: No astringency Panel out of 10 panelists answered no astringency Number of respondents: 8 to 9 Number of respondents with convergent property: 1 to 2 △: Somewhat convergent Some of the 10 panelists who answered that there was no astringent property: 6 to 7 persons who answered that they had convergent property: 3 to 4 ×: Convergence Number of panelists who did not converge out of 10 panelists: 0 to 5 persons Number of panelists who converged: 5 to 10 panelists

[0025]

[Table 1]

[0026]

[Table 2]

From the results in Tables 1 and 2, when the above-mentioned waxes are not blended (Comparative Examples 1 to 6), the waxes are astringent (Examples 1 to 9). Astringency was significantly improved.

Example 10 Toothpaste (Astringency evaluation: ○) Purified lanolin 1% Sodium pyrophosphate 2 Potassium pyrophosphate 3 Silicic anhydride 10 Propylene glycol 3 Glycerin (85%) 25 CMC 1.2 Lauroyl sarcosinate Sodium 0.3 Sodium lauryl sulfate 1 Tranexamic acid 0.05 Sodium fluoride 0.21 Saccharin sodium 0.1 Fragrance 1.2 Purified water Balance 100%

[Example 11] Toothpaste (astringency evaluation: A) Carnauba wax 0.5% Sodium tripolyphosphate 2 Silicic anhydride 20 Propylene glycol 2 Sorbitol (70%) 30 Xanthan gum 0.8 Carrageenan 0.4 Sodium lauryl sulfate 1.5 Epsilon aminocaproic acid 0.05 Sodium fluoride 0.21 Saccharin sodium 0.2 Fragrance 1 Purified water Balance 100%

Example 12 Toothpaste (Astringency evaluation: ②) Beeswax 3% Aluminum lactate 1.2 Silicic anhydride 15 Propylene glycol 3 Glycerin (85%) 23 Xanthan gum 1.2 Sodium lauryl sulfate 1.2 Glycyrrhizic acid Dipotassium 0.05 Sodium fluoride 0.21 Saccharin sodium 0.1 Fragrance 1.3 Purified water Balance 100%

Example 13 Liquid Dentifrice (Evaluation of Astringency: A) Squalane 1.5% Allantoin 0.5 Silicic anhydride 10 Propylene glycol 5 Glycerin (85%) 15 Sorbitol (70%) 50 CMC 1 Lauroyl sarcosine Sodium citrate 0.4 Sodium lauryl sulfate 0.5 Sodium fluoride 0.21 Triclosan 0.05 Saccharin sodium 0.3 Perfume 0.6 Purified water Balance 100%

Example 14 Liquid Toothpaste (Astringency Evaluation: O) Purified Lanolin 7% Potassium Pyrophosphate 5 Tartaric Acid 0.5 Silicic Anhydride 10 Propylene Glycol 10 Glycerin (85%) 58 Xanthan Gum 0.6 Carrageenan 0.5 Sodium lauroyl sarcosinate 0.1 Sodium lauryl sulfate 1.2 Sodium fluoride 0.21 Sodium saccharin 0.4 Fragrance 1 Purified water Balance 100%

Example 15 Toothpaste (Astringency evaluation: ○) Purified lanolin 1.5% Sodium pyrophosphate 3 Allantoin 0.4 Silicic anhydride 15 Propylene glycol 2 Glycerin (85%) 20 CMC 1.2 Carrageenan 0 .2 Sodium lauryl sulfate 1.5 Tranexamic acid 0.05 Sodium monofluorophosphate 0.76 Sodium saccharin 0.2 Fragrance 1.2 Purified water Balance 100%

Example 16 Toothpaste (astringency evaluation: ：) Carnauba wax 0.8% potassium pyrophosphate 0.5 sodium tripolyphosphate 1 dibasic calcium phosphate 45 propylene glycol 3 sorbitol (70%) 30 CMC 1.5 lauroyl Sodium sarcosinate 0.2 Sodium lauryl sulfate 1 Epsilon aminocaproic acid 0.05 Triclosan 0.05 Sodium saccharin 0.3 Perfume 1 Purified water Balance 100%

Example 17 Toothpaste (astringency evaluation: ◎) Beeswax 1.5% sodium tripolyphosphate 0.5 phytic acid 0.8 dibasic calcium phosphate 40 propylene glycol 4 glycerin (85%) 35 xanthan gum 0.9 Carrageenan 0.3 Sodium lauryl sulfate 1.8 Dipotassium glycyrrhizinate 0.05 Sodium monofluorophosphate 0.76 Sodium saccharin 0.5 Perfume 0.6 Purified water Balance 100%

Example 18 Toothpaste (Astringency evaluation: ○) Purified lanolin 2% Aluminum lactate 1.2 Dibasic calcium phosphate 35 Propylene glycol 3 Sorbitol (70%) 40 CMC 0.6 Carrageenan 0.8 Sodium lauryl sulfate 2 Tranexamic acid 0.05 Epsilon aminocaproic acid 0.05 Saccharin sodium 0.15 Fragrance 0.8 Purified water Balance 100%

[Example 19] Toothpaste (astringency evaluation: A) Purified lanolin 8% sodium pyrophosphate 1 tartaric acid 0.8 dibasic calcium phosphate 45 propylene glycol 5 glycerin (85%) 25 xanthan gum 0.6 lauroyl sarcosine acid Sodium 0.4 Sodium lauryl sulfate 0.5 Sodium monofluorophosphate 0.76 Sodium saccharin 0.25 Fragrance 1.5 Purified water Balance 100%

Example 20 Toothpaste (Astringency evaluation: ◎) Purified lanolin 5% sodium pyrophosphate 0.5 sodium tripolyphosphate 0.8 aluminum hydroxide 45 propylene glycol 2.5 glycerin (85%) 25 CMC 1 0.2 Carrageenan 0.3 Sodium lauroyl sarcosinate 0.1 Sodium lauryl sulfate 1.2 Tranexamic acid 0.05 Triclosan 0.05 Sodium saccharin 0.2 Perfume 1 Purified water Balance 100%

[Example 21] Toothpaste (astringency evaluation: ○) Beeswax 0.5% Potassium pyrophosphate 1.5 Allantoin 1.2 Aluminum hydroxide 40 Propylene glycol 3 Sorbitol (70%) 30 Xanthan gum 0.6 Carrageenan 0.5 Sodium lauryl sulfate 1.5 Sodium monofluorophosphate 0.76 Sodium saccharin 0.3 Perfume 1.2 Purified water Balance 100%

[Example 22] Toothpaste (astringency evaluation: A) Carnauba wax 1.5% Tartaric acid 5 Aluminum hydroxide 35 Propylene glycol 5 Sorbitol (70%) 40 CMC 1.5 Sodium lauryl sulfate 2 Tranexamic acid 0.05 Saccharin sodium 0.25 Fragrance 1.5 Purified water Balance 100%

Example 23 Toothpaste (astringency evaluation: ○) Purified lanolin 2% potassium pyrophosphate 5 phytic acid 0.5 calcium carbonate 40 propylene glycol 3 glycerin (85%) 20 CMC 1 carrageenan 0.6 lauroyl monkey Sodium cosinate 0.2 Sodium lauryl sulfate 1.5 Saccharin sodium 0.4 Fragrance 1.3 Purified water Balance 100%

Example 24 Toothpaste (Astringency evaluation: ○) Carnauba wax 1.2% Sodium pyrophosphate 2 Sodium tripolyphosphate 1 Allantoin 0.2 Silicic anhydride 5 Calcium carbonate 35 Propylene glycol 4 Sorbitol (70%) 30 Xanthan gum 1 Carrageenan 0.2 Sodium lauryl sulfate 1.5 Saccharin sodium 0.15 Fragrance 0.8 Purified water Balance 100%

Example 25 Toothpaste (Judgment of astringency: A) Purified lanolin 0.5% Sodium pyrophosphate 3 butylparaben 0.02 Calcium carbonate 70 Sorbitol (70%) 2 Glycerin (85%) 8 Saccharin sodium 0 0.08 Sodium lauryl sulfate 2 Purified water Balance 100%

Example 26 Mouthwash (evaluation of astringency: ○) Beeswax 1% Sodium pyrophosphate 5 Ethanol 10 Glycerin (85%) 8 Saccharin sodium 0.1 Polyoxyethylene hydrogenated castor oil 1 Sodium benzoate 0.3 Perfume 0.5 Purified water Balance 100%

Example 27 Mouthwash (evaluation of astringency: A) Purified lanolin 2% Aluminum lactate 0.5 Ethanol 5 Sorbitol (70%) 10 Saccharin sodium 0.1 Pluronic F127 2 Sodium benzoate 0.3 Citric acid Sodium 0.5 Perfume 0.4 Purified water Balance 100%

[Example 28] Mouthwash (evaluation of astringency: A) Carnauba wax 1% Allantoin 0.5 Ethanol 8 Glycerin (85%) 12 Saccharin sodium 0.1 Polyoxyethylene hydrogenated castor oil 1.2 Sodium benzoate 0 0.3 Perfume 0.5 Purified water Balance 100%

Example 29 Mouth Freshener (Evaluation of Astringency: A) Purified Lanolin 0.8% Sodium Pyrophosphate 2 Ethanol 30 Glycerin (85%) 15 Saccharin Sodium 0.3 Polyoxyethylene Hydrogenated Castor Oil 3 Perfume 1 Purification Water balance 100%

Claims (1)

[Claims] 1. An oral composition containing a compound having an astringent property, wherein one or more waxes selected from lanolin and derivatives thereof, whale wax, carnauba wax, candelilla wax and beeswax are blended. An oral composition characterized by the following.