JP2000247880A - 脂肪分解促進剤 - Google Patents
脂肪分解促進剤Info
- Publication number
- JP2000247880A JP2000247880A JP11050342A JP5034299A JP2000247880A JP 2000247880 A JP2000247880 A JP 2000247880A JP 11050342 A JP11050342 A JP 11050342A JP 5034299 A JP5034299 A JP 5034299A JP 2000247880 A JP2000247880 A JP 2000247880A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- accelerating agent
- food
- formula
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 150000001875 compounds Chemical class 0.000 claims abstract description 46
- 235000013305 food Nutrition 0.000 claims abstract description 22
- 239000002537 cosmetic Substances 0.000 claims abstract description 11
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims abstract description 3
- 230000004130 lipolysis Effects 0.000 claims description 24
- 239000004480 active ingredient Substances 0.000 claims description 12
- 238000000605 extraction Methods 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 11
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract description 8
- 210000001789 adipocyte Anatomy 0.000 abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 8
- 241000196324 Embryophyta Species 0.000 abstract description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 6
- 241000555678 Citrus unshiu Species 0.000 abstract description 4
- 238000004440 column chromatography Methods 0.000 abstract description 4
- 239000000377 silicon dioxide Substances 0.000 abstract description 4
- 239000002904 solvent Substances 0.000 abstract description 4
- 241001140724 Citrus tachibana Species 0.000 abstract description 2
- 238000000354 decomposition reaction Methods 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 244000183685 Citrus aurantium Species 0.000 abstract 2
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 2
- 240000004542 Capparis mitchellii Species 0.000 abstract 1
- 235000000228 Citrus myrtifolia Nutrition 0.000 abstract 1
- 235000016646 Citrus taiwanica Nutrition 0.000 abstract 1
- 235000004098 Prunus caroliniana Nutrition 0.000 abstract 1
- 241001093501 Rutaceae Species 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 21
- 239000000203 mixture Substances 0.000 description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- 239000006071 cream Substances 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 239000000499 gel Substances 0.000 description 8
- 230000003579 anti-obesity Effects 0.000 description 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 241000700159 Rattus Species 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 235000019441 ethanol Nutrition 0.000 description 5
- 230000002366 lipolytic effect Effects 0.000 description 5
- 239000006210 lotion Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 208000008589 Obesity Diseases 0.000 description 4
- 235000012041 food component Nutrition 0.000 description 4
- 239000005417 food ingredient Substances 0.000 description 4
- 235000021588 free fatty acids Nutrition 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 235000020824 obesity Nutrition 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 150000001298 alcohols Chemical class 0.000 description 3
- 239000007853 buffer solution Substances 0.000 description 3
- 239000000839 emulsion Substances 0.000 description 3
- 201000010063 epididymitis Diseases 0.000 description 3
- 239000003925 fat Substances 0.000 description 3
- 235000019197 fats Nutrition 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 102000029816 Collagenase Human genes 0.000 description 2
- 108060005980 Collagenase Proteins 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- 210000000577 adipose tissue Anatomy 0.000 description 2
- 244000309464 bull Species 0.000 description 2
- 229960002424 collagenase Drugs 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000012156 elution solvent Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- 239000012456 homogeneous solution Substances 0.000 description 2
- 208000032839 leukemia Diseases 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229930014626 natural product Natural products 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 210000004003 subcutaneous fat Anatomy 0.000 description 2
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- DBGIVFWFUFKIQN-UHFFFAOYSA-N (+-)-Fenfluramine Chemical compound CCNC(C)CC1=CC=CC(C(F)(F)F)=C1 DBGIVFWFUFKIQN-UHFFFAOYSA-N 0.000 description 1
- DRCWOKJLSQUJPZ-DZGCQCFKSA-N (4ar,9as)-n-ethyl-1,4,9,9a-tetrahydrofluoren-4a-amine Chemical compound C1C2=CC=CC=C2[C@]2(NCC)[C@H]1CC=CC2 DRCWOKJLSQUJPZ-DZGCQCFKSA-N 0.000 description 1
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 description 1
- 229930182837 (R)-adrenaline Natural products 0.000 description 1
- 238000005160 1H NMR spectroscopy Methods 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 101001008429 Homo sapiens Nucleobindin-2 Proteins 0.000 description 1
- 101000879758 Homo sapiens Sjoegren syndrome nuclear autoantigen 1 Proteins 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- ZPXSCAKFGYXMGA-UHFFFAOYSA-N Mazindol Chemical compound N12CCN=C2C2=CC=CC=C2C1(O)C1=CC=C(Cl)C=C1 ZPXSCAKFGYXMGA-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 102100027441 Nucleobindin-2 Human genes 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 241000218657 Picea Species 0.000 description 1
- 102100037330 Sjoegren syndrome nuclear autoantigen 1 Human genes 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000001800 adrenalinergic effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000002830 appetite depressant Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 238000003287 bathing Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229940098773 bovine serum albumin Drugs 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- -1 colorings Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 229960005139 epinephrine Drugs 0.000 description 1
- 238000009207 exercise therapy Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 229960001582 fenfluramine Drugs 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229960000299 mazindol Drugs 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 238000001050 pharmacotherapy Methods 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000002250 progressing effect Effects 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 210000003207 subcutaneous adipocyte Anatomy 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000003871 white petrolatum Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pyrane Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11050342A JP2000247880A (ja) | 1999-02-26 | 1999-02-26 | 脂肪分解促進剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11050342A JP2000247880A (ja) | 1999-02-26 | 1999-02-26 | 脂肪分解促進剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009184150A Division JP5236593B2 (ja) | 2009-08-07 | 2009-08-07 | 脂肪分解促進剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000247880A true JP2000247880A (ja) | 2000-09-12 |
| JP2000247880A5 JP2000247880A5 (enExample) | 2005-08-04 |
Family
ID=12856258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11050342A Withdrawn JP2000247880A (ja) | 1999-02-26 | 1999-02-26 | 脂肪分解促進剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2000247880A (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006049234A1 (ja) | 2004-11-08 | 2006-05-11 | Arkray, Inc. | ペルオキシソーム増殖剤応答性受容体(ppar)活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物 |
| JP2008247826A (ja) * | 2007-03-30 | 2008-10-16 | Hiroshima Univ | 血糖値調整剤およびまたは血中コレステロール値調整剤 |
| KR100883356B1 (ko) * | 2006-08-16 | 2009-02-11 | 제주대학교 산학협력단 | 비만 개선제 조성물 |
| EP1928480A4 (en) * | 2005-08-23 | 2012-03-28 | Wellgen Inc | METHOD FOR TREATING ADIPOCYTE FAT ACCUMULATION |
-
1999
- 1999-02-26 JP JP11050342A patent/JP2000247880A/ja not_active Withdrawn
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006049234A1 (ja) | 2004-11-08 | 2006-05-11 | Arkray, Inc. | ペルオキシソーム増殖剤応答性受容体(ppar)活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物 |
| EP1829542A4 (en) * | 2004-11-08 | 2009-05-27 | Arkray Inc | PEROXISOM PROLIFERATOR ACTIVATED RECEPTOR (PPAR) ACTIVATOR AND MEDICAMENT, COMPLEMENTARY AGENT, FUNCTIONAL FOOD AND FOOD SUPPLEMENT THEREOF |
| JP2013163685A (ja) * | 2004-11-08 | 2013-08-22 | Arkray Inc | ペルオキシソーム増殖剤応答性受容体(ppar)活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物 |
| JP2013163684A (ja) * | 2004-11-08 | 2013-08-22 | Arkray Inc | ペルオキシソーム増殖剤応答性受容体(ppar)活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物 |
| JP5473191B2 (ja) * | 2004-11-08 | 2014-04-16 | アークレイ株式会社 | ペルオキシソーム増殖剤応答性受容体(ppar)活性化剤、ならびにそれを用いた医薬、サプリメント、機能性食品および食品添加物 |
| US9573919B2 (en) | 2004-11-08 | 2017-02-21 | Arkray, Inc. | Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same |
| EP1928480A4 (en) * | 2005-08-23 | 2012-03-28 | Wellgen Inc | METHOD FOR TREATING ADIPOCYTE FAT ACCUMULATION |
| KR100883356B1 (ko) * | 2006-08-16 | 2009-02-11 | 제주대학교 산학협력단 | 비만 개선제 조성물 |
| JP2008247826A (ja) * | 2007-03-30 | 2008-10-16 | Hiroshima Univ | 血糖値調整剤およびまたは血中コレステロール値調整剤 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0282002B1 (en) | Compositions of oats and nettle extracts to be used as a food additive or pharmaceutical preparation in human health care | |
| US8569247B2 (en) | Hydrolysate of crocin | |
| JP2002179586A (ja) | リパーゼ阻害剤 | |
| JP2002121145A (ja) | キサンチンオキシダーゼ阻害剤 | |
| JP4002654B2 (ja) | 血中脂質改善剤、サイクリックampホスホジエステラーゼ阻害剤、及び肥満の予防・解消剤、並びに飲食品及び皮膚外用剤 | |
| JP5773111B2 (ja) | 皮膚の色素沈着を抑制する組成物およびその利用 | |
| JP4325908B2 (ja) | 脂肪分解促進剤ならびにそれを用いた皮膚外用剤および飲食物 | |
| KR102137136B1 (ko) | 호박 가수분해 추출물, 구약감자 가수분해 추출물, 강황 추출물 및 카카오닙스 추출물을 포함하는 조성물 | |
| JP2000247880A (ja) | 脂肪分解促進剤 | |
| JPH10287582A (ja) | 樹皮抽出物からなるヒスタミン遊離抑制剤 | |
| CA2540849A1 (en) | Plant seed extract composition and process for producing the same | |
| JP2009203209A (ja) | アカシア属樹皮由来物を含有する血糖降下及び/又は抗肥満組成物 | |
| JP4421847B2 (ja) | 脂肪分解促進剤 | |
| JP4105498B2 (ja) | アトピー性疾患の症状の予防・緩和に有効な組成物 | |
| JP5236593B2 (ja) | 脂肪分解促進剤 | |
| KR101273027B1 (ko) | 캄페롤을 유효성분으로 함유하는 피지 분비 억제용 및항비만용 조성물 | |
| JP3068551B2 (ja) | 痩身剤 | |
| JP4530442B2 (ja) | サイクリックampホスホジエステラーゼ阻害剤、皮膚外用剤 | |
| JP2013245171A (ja) | ヘンナの花部抽出物の取得方法 | |
| CN110404029B (zh) | 一种具有降血糖功效的组合物及其制备方法和应用 | |
| WO2018212147A1 (ja) | 肌くすみ抑制剤及び肌バリア機能維持又は改善剤 | |
| JP2001089388A (ja) | 抗腫瘍性組成物およびその製造法 | |
| JP7262760B2 (ja) | シワ予防・改善用の医薬品、医薬部外品、化粧料又は飲食品組成物 | |
| JP2002173434A (ja) | 抗アレルギー性組成物 | |
| JP4406503B2 (ja) | 新規肝障害抑制剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20041227 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20041227 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20080827 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080909 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081107 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20081107 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090507 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090807 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20090918 |