JP2000053523A5 - - Google Patents
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- Publication number
- JP2000053523A5 JP2000053523A5 JP1998236495A JP23649598A JP2000053523A5 JP 2000053523 A5 JP2000053523 A5 JP 2000053523A5 JP 1998236495 A JP1998236495 A JP 1998236495A JP 23649598 A JP23649598 A JP 23649598A JP 2000053523 A5 JP2000053523 A5 JP 2000053523A5
- Authority
- JP
- Japan
- Prior art keywords
- melanin production
- control
- cells
- inhibitory effect
- production inhibitory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000008099 melanin synthesis Effects 0.000 description 12
- 230000002401 inhibitory effect Effects 0.000 description 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 6
- 239000003112 inhibitor Substances 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 241001632410 Eleutherococcus senticosus Species 0.000 description 2
- 230000003013 cytotoxicity Effects 0.000 description 2
- 231100000135 cytotoxicity Toxicity 0.000 description 2
- 201000001441 melanoma Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- UGVIZCBJCSXBCJ-JWFUOXDNSA-N (1ar,7r,7ar,7bs)-1,1,7,7a-tetramethyl-1a,4,5,6,7,7b-hexahydrocyclopropa[a]naphthalen-2-one Chemical compound O=C1[C@H]2C(C)(C)[C@H]2[C@@]2(C)[C@H](C)CCCC2=C1 UGVIZCBJCSXBCJ-JWFUOXDNSA-N 0.000 description 1
- 241000046585 Aristolochia clematitis Species 0.000 description 1
- 239000012980 RPMI-1640 medium Substances 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- UGVIZCBJCSXBCJ-UHFFFAOYSA-N aristolone Natural products O=C1C2C(C)(C)C2C2(C)C(C)CCCC2=C1 UGVIZCBJCSXBCJ-UHFFFAOYSA-N 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 238000010898 silica gel chromatography Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23649598A JP3869949B2 (ja) | 1998-08-07 | 1998-08-07 | 美白に好適な皮膚外用剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23649598A JP3869949B2 (ja) | 1998-08-07 | 1998-08-07 | 美白に好適な皮膚外用剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000053523A JP2000053523A (ja) | 2000-02-22 |
| JP2000053523A5 true JP2000053523A5 (https=) | 2005-10-20 |
| JP3869949B2 JP3869949B2 (ja) | 2007-01-17 |
Family
ID=17001586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP23649598A Expired - Fee Related JP3869949B2 (ja) | 1998-08-07 | 1998-08-07 | 美白に好適な皮膚外用剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3869949B2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002363057A (ja) * | 2001-06-08 | 2002-12-18 | Ichimaru Pharcos Co Ltd | メラニン生成抑制剤又は化粧料組成物 |
| KR101558526B1 (ko) * | 2015-03-25 | 2015-10-12 | 이노스킨 주식회사 | 붉은싸리버섯 추출물을 유효성분으로 함유하는 항노화용 조성물 |
-
1998
- 1998-08-07 JP JP23649598A patent/JP3869949B2/ja not_active Expired - Fee Related
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