ITUB20152860A1 - Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool - Google Patents
Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool Download PDFInfo
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- ITUB20152860A1 ITUB20152860A1 ITUB2015A002860A ITUB20152860A ITUB20152860A1 IT UB20152860 A1 ITUB20152860 A1 IT UB20152860A1 IT UB2015A002860 A ITUB2015A002860 A IT UB2015A002860A IT UB20152860 A ITUB20152860 A IT UB20152860A IT UB20152860 A1 ITUB20152860 A1 IT UB20152860A1
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- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 235000013874 shellac Nutrition 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
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- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2015A002860A ITUB20152860A1 (it) | 2015-08-04 | 2015-08-04 | Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool |
| ES16791313T ES2776628T3 (es) | 2015-08-04 | 2016-08-03 | Amida seleccionada del ácido ?-hidroxibutírico y usos de la misma en el tratamiento del uso inapropiado del alcohol |
| BR112018002245-4A BR112018002245B1 (pt) | 2015-08-04 | 2016-08-03 | Composto amida selecionado do ácido ?-hidroxybutírico, processo para a preparação do referido composto, uso do referido composto e composição farmacêutica compreendendo o referido composto |
| CN201680045364.9A CN108026029B (zh) | 2015-08-04 | 2016-08-03 | 经选择的γ-羟基丁酸的酰胺及其在治疗酒精误用中的用途 |
| CA2994599A CA2994599C (en) | 2015-08-04 | 2016-08-03 | Selected amide of y -hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| EA201890419A EA033769B9 (ru) | 2015-08-04 | 2016-08-03 | Отселектированный амид -гидроксимасляной кислоты и его применения при лечении злоупотребления алкоголем |
| US15/750,047 US10336687B2 (en) | 2015-08-04 | 2016-08-03 | Selected amide of Y-hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| SM20200337T SMT202000337T1 (it) | 2015-08-04 | 2016-08-03 | Selezionata ammide dell'acido y-idrossibutirrico e suoi usi nel trattamento dell'abuso di alcool |
| UAA201801726A UA121994C2 (uk) | 2015-08-04 | 2016-08-03 | СЕЛЕКТИВНИЙ АМІД <font face="Symbol">g</font>-ГІДРОКСИМАСЛЯНОЇ КИСЛОТИ ТА ЙОГО ВИКОРИСТАННЯ ПРИ ЛІКУВАННІ ЗЛОВЖИВАННЯ АЛКОГОЛЕМ |
| JP2018502356A JP6832336B2 (ja) | 2015-08-04 | 2016-08-03 | アルコール乱用の治療におけるγ−ヒドロキシ酪酸の選択されたアミドおよびその使用 |
| PCT/EP2016/068517 WO2017021438A1 (en) | 2015-08-04 | 2016-08-03 | SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE |
| KR1020187006231A KR102817897B1 (ko) | 2015-08-04 | 2016-08-03 | γ-히드록시부티르산의 선택 아미드 및 알코올 오남용의 치료에서의 이의 용도 |
| DK16791313.6T DK3331853T3 (da) | 2015-08-04 | 2016-08-03 | Udvalgt amid af -hydroxybutansyre og anvendelser deraf i behandlingen af alkoholmisbrug |
| PT167913136T PT3331853T (pt) | 2015-08-04 | 2016-08-03 | Amida selecionada de ácido γ-hidroxibutírico e suas utilizações no tratamento de abuso de álcool |
| MX2018001239A MX2018001239A (es) | 2015-08-04 | 2016-08-03 | Amida seleccionada de acido gamma-hidroxibutirico y usos de la misma en el tratamiento de abuso de alcohol. |
| EP16791313.6A EP3331853B1 (en) | 2015-08-04 | 2016-08-03 | Selected amide of -hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| GEAP201614717A GEP20207107B (en) | 2015-08-04 | 2016-08-03 | Selected amide of γ-hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| AU2016302869A AU2016302869B2 (en) | 2015-08-04 | 2016-08-03 | Selected amide of gamma-hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| PL16791313T PL3331853T3 (pl) | 2015-08-04 | 2016-08-03 | Wybrany amid kwasu γ-hydroksymasłowego i jego zastosowania w leczeniu niewłaściwego użycia alkoholu |
| MYPI2018700405A MY185942A (en) | 2015-08-04 | 2016-08-03 | Selected amide of y-hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| CL2018000282A CL2018000282A1 (es) | 2015-08-04 | 2018-01-31 | Amida seleccionada de ácido gamma-hidroxibutírico y usos de la misma en el tratamiento de abuso de alcohol |
| IL257314A IL257314B (en) | 2015-08-04 | 2018-02-01 | A selected amide of gamma-hydroxybutyric acid and its uses in the treatment of alcohol abuse |
| PH12018550008A PH12018550008A1 (en) | 2015-08-04 | 2018-02-02 | Selected amide of y-hydroxybutyric acid and uses thereof in the treatment of alcohol misuse |
| ZA2018/01402A ZA201801402B (en) | 2015-08-04 | 2018-02-28 | SELECTED AMIDE OF γ -HYDROXYBUTYRIC ACID AND USES THEREOF IN THE TREATMENT OF ALCOHOL MISUSE |
| CONC2018/0002428A CO2018002428A2 (es) | 2015-08-04 | 2018-03-02 | Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITUB2015A002860A ITUB20152860A1 (it) | 2015-08-04 | 2015-08-04 | Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITUB20152860A1 true ITUB20152860A1 (it) | 2017-02-04 |
Family
ID=54542363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITUB2015A002860A ITUB20152860A1 (it) | 2015-08-04 | 2015-08-04 | Selezionata amide dell?acido ?-idrossibutirrico e suoi usi nel trattamento dell?abuso da alcool |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US10336687B2 (OSRAM) |
| EP (1) | EP3331853B1 (OSRAM) |
| JP (1) | JP6832336B2 (OSRAM) |
| KR (1) | KR102817897B1 (OSRAM) |
| CN (1) | CN108026029B (OSRAM) |
| AU (1) | AU2016302869B2 (OSRAM) |
| CA (1) | CA2994599C (OSRAM) |
| CL (1) | CL2018000282A1 (OSRAM) |
| CO (1) | CO2018002428A2 (OSRAM) |
| DK (1) | DK3331853T3 (OSRAM) |
| EA (1) | EA033769B9 (OSRAM) |
| ES (1) | ES2776628T3 (OSRAM) |
| GE (1) | GEP20207107B (OSRAM) |
| IL (1) | IL257314B (OSRAM) |
| IT (1) | ITUB20152860A1 (OSRAM) |
| MX (1) | MX2018001239A (OSRAM) |
| MY (1) | MY185942A (OSRAM) |
| PH (1) | PH12018550008A1 (OSRAM) |
| PL (1) | PL3331853T3 (OSRAM) |
| PT (1) | PT3331853T (OSRAM) |
| SM (1) | SMT202000337T1 (OSRAM) |
| UA (1) | UA121994C2 (OSRAM) |
| WO (1) | WO2017021438A1 (OSRAM) |
| ZA (1) | ZA201801402B (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3066711A1 (en) | 2017-07-31 | 2019-02-07 | Novartis Ag | Use of mavoglurant in the reduction of cocaine use or in preventing relapse into cocaine use |
| US12201612B2 (en) | 2017-07-31 | 2025-01-21 | Novartis Ag | Use of mavoglurant in the reduction of alcohol use or in preventing relapse into alcohol use |
| CN113185403A (zh) * | 2021-07-02 | 2021-07-30 | 山东国邦药业有限公司 | 一种甲醚制备环丙胺中间体环丙甲酸甲酯的方法 |
| WO2023126076A1 (en) * | 2022-01-03 | 2023-07-06 | Laboratorio Farmaceutico C.T. S.R.L. | Medical use of an amide of y-hydroxybutyric acid in the treatment of fragile x syndrome |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998006690A1 (en) * | 1996-08-09 | 1998-02-19 | Laboratorio Farmaceutico C.T. S.R.L. | USE OF η-HYDROXYBUTYRIC ACID AMIDES IN THE TREATMENT OF DRUG ADDICTION AND IN PARTICULAR OF ALCOHOLISM |
-
2015
- 2015-08-04 IT ITUB2015A002860A patent/ITUB20152860A1/it unknown
-
2016
- 2016-08-03 KR KR1020187006231A patent/KR102817897B1/ko active Active
- 2016-08-03 ES ES16791313T patent/ES2776628T3/es active Active
- 2016-08-03 GE GEAP201614717A patent/GEP20207107B/en unknown
- 2016-08-03 US US15/750,047 patent/US10336687B2/en active Active
- 2016-08-03 PT PT167913136T patent/PT3331853T/pt unknown
- 2016-08-03 DK DK16791313.6T patent/DK3331853T3/da active
- 2016-08-03 JP JP2018502356A patent/JP6832336B2/ja not_active Expired - Fee Related
- 2016-08-03 AU AU2016302869A patent/AU2016302869B2/en not_active Ceased
- 2016-08-03 UA UAA201801726A patent/UA121994C2/uk unknown
- 2016-08-03 MY MYPI2018700405A patent/MY185942A/en unknown
- 2016-08-03 CN CN201680045364.9A patent/CN108026029B/zh not_active Expired - Fee Related
- 2016-08-03 MX MX2018001239A patent/MX2018001239A/es active IP Right Grant
- 2016-08-03 WO PCT/EP2016/068517 patent/WO2017021438A1/en not_active Ceased
- 2016-08-03 EA EA201890419A patent/EA033769B9/ru not_active IP Right Cessation
- 2016-08-03 SM SM20200337T patent/SMT202000337T1/it unknown
- 2016-08-03 PL PL16791313T patent/PL3331853T3/pl unknown
- 2016-08-03 EP EP16791313.6A patent/EP3331853B1/en active Active
- 2016-08-03 CA CA2994599A patent/CA2994599C/en active Active
-
2018
- 2018-01-31 CL CL2018000282A patent/CL2018000282A1/es unknown
- 2018-02-01 IL IL257314A patent/IL257314B/en active IP Right Grant
- 2018-02-02 PH PH12018550008A patent/PH12018550008A1/en unknown
- 2018-02-28 ZA ZA2018/01402A patent/ZA201801402B/en unknown
- 2018-03-02 CO CONC2018/0002428A patent/CO2018002428A2/es unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998006690A1 (en) * | 1996-08-09 | 1998-02-19 | Laboratorio Farmaceutico C.T. S.R.L. | USE OF η-HYDROXYBUTYRIC ACID AMIDES IN THE TREATMENT OF DRUG ADDICTION AND IN PARTICULAR OF ALCOHOLISM |
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