ITMI20020871A0 - Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono - Google Patents
Derivati alogenati dell'iperforina loro uso e formulazioni che li contengonoInfo
- Publication number
- ITMI20020871A0 ITMI20020871A0 IT2002MI000871A ITMI20020871A ITMI20020871A0 IT MI20020871 A0 ITMI20020871 A0 IT MI20020871A0 IT 2002MI000871 A IT2002MI000871 A IT 2002MI000871A IT MI20020871 A ITMI20020871 A IT MI20020871A IT MI20020871 A0 ITMI20020871 A0 IT MI20020871A0
- Authority
- IT
- Italy
- Prior art keywords
- hyperforin
- formulations
- contain
- halogenated derivatives
- halogenated
- Prior art date
Links
- KGSZHKRKHXOAMG-HQKKAZOISA-N (1r,5r,6r,7s)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione Chemical class O=C1C(CC=C(C)C)=C(O)[C@@]2(CC=C(C)C)C[C@H](CC=C(C)C)[C@](CCC=C(C)C)(C)[C@]1(C(=O)C(C)C)C2=O KGSZHKRKHXOAMG-HQKKAZOISA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/693—Unsaturated compounds containing a keto groups being part of a ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/512—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being a free hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/457—Saturated compounds containing a keto group being part of a ring containing halogen
- C07C49/467—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic
- C07C49/473—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic a keto group being part of a condensed ring system
- C07C49/477—Saturated compounds containing a keto group being part of a ring containing halogen polycyclic a keto group being part of a condensed ring system having two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
- C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
- C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000871A ITMI20020871A1 (it) | 2002-04-23 | 2002-04-23 | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono |
PL03372166A PL372166A1 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
JP2003587761A JP2005523916A (ja) | 2002-04-23 | 2003-04-15 | ヒペルフォリンのハロゲン化誘導体、それらの使用、およびそれらを含む製剤 |
RU2004131220/04A RU2004131220A (ru) | 2002-04-23 | 2003-04-15 | Галогенпроизводные гиперфорина, использование таковых и составов, их содержащих |
EP03727312A EP1497249A1 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
CNB038089645A CN1269783C (zh) | 2002-04-23 | 2003-04-15 | 贯叶金丝桃素卤代衍生物、其用途和包含它们的制剂 |
CA002483203A CA2483203A1 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
AU2003233979A AU2003233979B2 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
KR10-2004-7016809A KR20040111537A (ko) | 2002-04-23 | 2003-04-15 | 하이퍼포린의 할로겐화된 유도체, 그의 용도 및 그를함유한 제제 |
US10/511,894 US7057078B2 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
PCT/EP2003/003923 WO2003091193A1 (en) | 2002-04-23 | 2003-04-15 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
NO20044518A NO20044518L (no) | 2002-04-23 | 2004-10-21 | Halogenerte hyperfonnderivater, anvendelse derav samt formuleringer som inneholder dem |
HK05107778A HK1075653A1 (en) | 2002-04-23 | 2005-09-05 | Hyperforin halogenated derivatives, the use thereof and formulations containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002MI000871A ITMI20020871A1 (it) | 2002-04-23 | 2002-04-23 | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20020871A0 true ITMI20020871A0 (it) | 2002-04-23 |
ITMI20020871A1 ITMI20020871A1 (it) | 2003-10-23 |
Family
ID=11449766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT2002MI000871A ITMI20020871A1 (it) | 2002-04-23 | 2002-04-23 | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono |
Country Status (13)
Country | Link |
---|---|
US (1) | US7057078B2 (it) |
EP (1) | EP1497249A1 (it) |
JP (1) | JP2005523916A (it) |
KR (1) | KR20040111537A (it) |
CN (1) | CN1269783C (it) |
AU (1) | AU2003233979B2 (it) |
CA (1) | CA2483203A1 (it) |
HK (1) | HK1075653A1 (it) |
IT (1) | ITMI20020871A1 (it) |
NO (1) | NO20044518L (it) |
PL (1) | PL372166A1 (it) |
RU (1) | RU2004131220A (it) |
WO (1) | WO2003091193A1 (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102772461B (zh) * | 2011-05-11 | 2014-05-14 | 成都康弘药业集团股份有限公司 | 药物组合物在制备预防或治疗老年性痴呆的药物中的应用 |
KR20140041610A (ko) * | 2011-06-03 | 2014-04-04 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 하이퍼포린 유사체, 합성 방법 및 그의 용도 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1054682B1 (de) * | 1998-02-13 | 2001-08-29 | Dr. Willmar Schwabe GmbH & Co. | Verwendung von hyperforin und hyperforinhaltigen extrakten zur behandlung und prophylaxe von demenzerkrankungen |
AU743956B2 (en) * | 1998-02-13 | 2002-02-07 | Dr. Willmar Schwabe Gmbh & Co | Stable hyperforin salts, method for producing same and their use in the treatment of Alzheimer's disease |
IT1301679B1 (it) * | 1998-06-10 | 2000-07-07 | Indena Spa | Derivati dell'iperforina, loro uso e formulazioni che licontengono. |
-
2002
- 2002-04-23 IT IT2002MI000871A patent/ITMI20020871A1/it unknown
-
2003
- 2003-04-15 AU AU2003233979A patent/AU2003233979B2/en not_active Expired - Fee Related
- 2003-04-15 JP JP2003587761A patent/JP2005523916A/ja not_active Withdrawn
- 2003-04-15 RU RU2004131220/04A patent/RU2004131220A/ru not_active Application Discontinuation
- 2003-04-15 US US10/511,894 patent/US7057078B2/en not_active Expired - Fee Related
- 2003-04-15 KR KR10-2004-7016809A patent/KR20040111537A/ko not_active Application Discontinuation
- 2003-04-15 CN CNB038089645A patent/CN1269783C/zh not_active Expired - Fee Related
- 2003-04-15 WO PCT/EP2003/003923 patent/WO2003091193A1/en not_active Application Discontinuation
- 2003-04-15 PL PL03372166A patent/PL372166A1/xx unknown
- 2003-04-15 CA CA002483203A patent/CA2483203A1/en not_active Abandoned
- 2003-04-15 EP EP03727312A patent/EP1497249A1/en not_active Withdrawn
-
2004
- 2004-10-21 NO NO20044518A patent/NO20044518L/no not_active Application Discontinuation
-
2005
- 2005-09-05 HK HK05107778A patent/HK1075653A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2003233979B2 (en) | 2008-02-21 |
RU2004131220A (ru) | 2005-04-20 |
US20050222274A1 (en) | 2005-10-06 |
CN1269783C (zh) | 2006-08-16 |
KR20040111537A (ko) | 2004-12-31 |
JP2005523916A (ja) | 2005-08-11 |
ITMI20020871A1 (it) | 2003-10-23 |
PL372166A1 (en) | 2005-07-11 |
AU2003233979A1 (en) | 2003-11-10 |
EP1497249A1 (en) | 2005-01-19 |
HK1075653A1 (en) | 2005-12-23 |
NO20044518L (no) | 2004-11-19 |
WO2003091193A1 (en) | 2003-11-06 |
US7057078B2 (en) | 2006-06-06 |
CN1646461A (zh) | 2005-07-27 |
CA2483203A1 (en) | 2003-11-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1478339T3 (da) | Farmaceutiske formuleringer af antineoplastiske midler, specielt temozolomid, fremgangsmåder til fremstilling og anvendelse heraf | |
DK1329456T3 (da) | Glucopyranosyloxybenzylbenzenderivater og medicinske sammensætninger indeholdende samme | |
ID22565A (id) | Penggunaan nanodispersi dalam formulasi akhir obat | |
DK2455083T3 (da) | Farmaceutisk sammensætning til dermal anvendelse omfattende calcipotriol og betamethason til behandling af psoriasis | |
DK1480615T3 (da) | Superfin formoterolformulering | |
EE04799B1 (et) | Ühendid, mis on kasulikud põletikuvastaste vahenditena, nende ühendite valmistamise meetodid ja neid sisaldavad farmatseutilised kompositsioonid | |
DK1242095T3 (da) | Antimikrobielle sammensætninger og fremgangsmåder til anvendelse deraf | |
AR028570A1 (es) | Composiciones de polipcptidos tnxicas contra insectos anthonomus y mctodos para el uso de las mismas | |
DK1453517T3 (da) | Farmaceutiske formuleringer med platinderivat | |
NO20024099D0 (no) | Lavdose entecavir-formulering og anvendelse | |
NO20041272L (no) | Tetracycline derivatives and methods of use thereof | |
EE05333B1 (et) | Makroliidhendite konjugaadid p?letikuvastaste henditega ja nende kasutamine | |
NO20034778D0 (no) | Farmasöytiske sammensetninger for oral og topisk anvendelse | |
NO20043333L (no) | Farmasoytiske parvastatinformuleringer og fremgangsmater for anvendelse av dem | |
PT1187847E (pt) | Derivados de estreptograminas sua preparacao e as composicoes que os contem | |
ITMI20010957A0 (it) | Derivati dell'aoe-emodina e loro impiego nel trattamento di patologieneoplastiche | |
NO20030156L (no) | Farmasöytiske sammensetninger og fremgangsmåter for anvendelse derav | |
ITMI20020871A0 (it) | Derivati alogenati dell'iperforina loro uso e formulazioni che li contengono | |
ITMI20020872A0 (it) | Derivati dell'iperforina loro uso e formulazioni che li contengono | |
ITMI20000554A0 (it) | Derivati di n-desacetiltiocolchicina e composizioni farmaceutiche cheli contengono | |
ITRM20030394A0 (it) | Uso dell'indometacina e derivati come farmaci antivirali e relative composizioni farmaceutiche. | |
EE200300454A (et) | Bitsüklilised guanidiini derivaadid ja nende terapeutiline kasutamine | |
ITRM20020119A1 (it) | Composizioni contenenti plgf ad uso farmaceutico e cosmetico. | |
ITMI20020951A1 (it) | Derivati multifunzionali del polietilenglicole loro preparazione ed impiego | |
DK1429770T3 (da) | Nye formuleringer og anvendelse deraf |