ITMI20011401A0 - Formulazioni farmaceutiche per ormoni tiroidei - Google Patents

Formulazioni farmaceutiche per ormoni tiroidei

Info

Publication number
ITMI20011401A0
ITMI20011401A0 IT2001MI001401A ITMI20011401A ITMI20011401A0 IT MI20011401 A0 ITMI20011401 A0 IT MI20011401A0 IT 2001MI001401 A IT2001MI001401 A IT 2001MI001401A IT MI20011401 A ITMI20011401 A IT MI20011401A IT MI20011401 A0 ITMI20011401 A0 IT MI20011401A0
Authority
IT
Italy
Prior art keywords
pharmaceutical formulations
thyroid hormones
thyroid
hormones
formulations
Prior art date
Application number
IT2001MI001401A
Other languages
English (en)
Inventor
Alberto Garavani
Maurizio Marchiorri
Martino Alessandro Di
Original Assignee
Altergon Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11447983&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ITMI20011401(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Altergon Sa filed Critical Altergon Sa
Priority to IT2001MI001401A priority Critical patent/ITMI20011401A1/it
Publication of ITMI20011401A0 publication Critical patent/ITMI20011401A0/it
Priority to CA2392545A priority patent/CA2392545C/en
Priority to EP02014594A priority patent/EP1291021B1/en
Priority to ES02014594T priority patent/ES2254559T3/es
Priority to JP2002193024A priority patent/JP5105685B2/ja
Priority to AT02014594T priority patent/ATE312621T1/de
Priority to DK02014594T priority patent/DK1291021T3/da
Priority to US10/188,467 priority patent/US7723390B2/en
Priority to DE60207951T priority patent/DE60207951T2/de
Publication of ITMI20011401A1 publication Critical patent/ITMI20011401A1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT2001MI001401A 2001-07-02 2001-07-02 Formulazioni farmaceutiche per ormoni tiroidei ITMI20011401A1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT2001MI001401A ITMI20011401A1 (it) 2001-07-02 2001-07-02 Formulazioni farmaceutiche per ormoni tiroidei
CA2392545A CA2392545C (en) 2001-07-02 2002-06-28 Pharmaceutical formulations for thyroid hormones
DE60207951T DE60207951T2 (de) 2001-07-02 2002-07-02 Pharmazeutische Formulierungen von Thyroidhormonen
US10/188,467 US7723390B2 (en) 2001-07-02 2002-07-02 Pharmaceutical formulations for thyroid hormones
ES02014594T ES2254559T3 (es) 2001-07-02 2002-07-02 Formulaciones farmaceuticas de hormonas tiroideas.
EP02014594A EP1291021B1 (en) 2001-07-02 2002-07-02 Pharmaceutical formulations for thyroid hormones
JP2002193024A JP5105685B2 (ja) 2001-07-02 2002-07-02 甲状腺ホルモンの製薬化
AT02014594T ATE312621T1 (de) 2001-07-02 2002-07-02 Pharmazeutische formulierungen von thyroidhormonen
DK02014594T DK1291021T3 (da) 2001-07-02 2002-07-02 Farmaceutiske formuleringer som omfatter thyroideahormoner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001MI001401A ITMI20011401A1 (it) 2001-07-02 2001-07-02 Formulazioni farmaceutiche per ormoni tiroidei

Publications (2)

Publication Number Publication Date
ITMI20011401A0 true ITMI20011401A0 (it) 2001-07-02
ITMI20011401A1 ITMI20011401A1 (it) 2003-01-02

Family

ID=11447983

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2001MI001401A ITMI20011401A1 (it) 2001-07-02 2001-07-02 Formulazioni farmaceutiche per ormoni tiroidei

Country Status (9)

Country Link
US (1) US7723390B2 (it)
EP (1) EP1291021B1 (it)
JP (1) JP5105685B2 (it)
AT (1) ATE312621T1 (it)
CA (1) CA2392545C (it)
DE (1) DE60207951T2 (it)
DK (1) DK1291021T3 (it)
ES (1) ES2254559T3 (it)
IT (1) ITMI20011401A1 (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163918B2 (en) * 2000-08-22 2007-01-16 New River Pharmaceuticals Inc. Iodothyronine compositions
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
ITMI20022394A1 (it) 2002-11-13 2004-05-14 Bracco Spa Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche.
ITMI20110713A1 (it) 2011-04-29 2012-10-30 Bracco Imaging Spa Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina
ITMI20022777A1 (it) 2002-12-27 2004-06-28 Altergon Sa Formulazioni farmaceutiche per ormoni tiroidei e procedimenti per il loro ottenimento.
EP1762232A1 (en) * 2005-09-09 2007-03-14 Warner-Lambert Company LLC Liquid filled delivery system, preferably an HPMC capsule filled with glycerol
GB0606212D0 (en) * 2006-03-28 2006-05-10 Karobio Ab Pharmaceutical compositions
ES2396502T3 (es) * 2006-09-19 2013-02-22 Genzyme Corporation Formulaciones para la administración terapéutica de la hormona estimulante de la tiroides (TSH)
GB0724478D0 (en) * 2007-12-14 2008-01-30 Karobio Ab Pharmaceutical compositions
IT1393524B1 (it) * 2009-01-30 2012-04-27 Altergon Sa Contenitore per uso farmaceutico atto al rilascio quantitativo di una monodose per somministrazione orale di ormoni tiroidei t3 e t4 in soluzione
IT1395454B1 (it) * 2009-03-24 2012-09-21 Altergon Sa Composizioni e forme farmaceutiche per somministrazione orale di ormoni tiroidei in grado di contrastare l'azione di agenti sequestranti nel tratto gastrointestinale
WO2011015953A2 (en) * 2009-08-04 2011-02-10 Haren Treasurer Greater utility with thyroid hormone
MX348467B (es) * 2011-04-08 2017-06-13 Bracco Imaging Spa Proceso para la preparación de un derivado sulfatado de 3,5-diiodo-o-[3-iodofenil]-l-tirosina.
ITMI20112066A1 (it) * 2011-11-14 2013-05-15 Altergon Sa Preparazione farmaceutica orale monodose di ormoni tiroidei t3 e t4
DE102013017917A1 (de) * 2013-10-26 2015-04-30 Michael Raschke L-Thyrogal
US9345772B1 (en) 2015-02-27 2016-05-24 Nilesh Parikh Liquid levothyroxine formulations
EP3682872B1 (en) 2015-03-26 2024-01-03 Patheon Softgels Inc. Liquisoft capsules
WO2016185378A1 (en) * 2015-05-19 2016-11-24 Altergon S.A. Liquid pharmaceutical formulations of tetraiodothyronine
ITUB20156821A1 (it) * 2015-12-09 2017-06-09 Altergon Sa CAPSULE DI GELATINA MOLLE A RILASCIO pH INDIPENDENTE
EP3311844A1 (en) 2016-10-18 2018-04-25 Altergon S.A. High-stability packaged solutions of t4 thyroid hormone
JP6942342B2 (ja) * 2016-11-02 2021-09-29 富士カプセル株式会社 ソフトカプセル皮膜
US9782376B1 (en) 2016-12-01 2017-10-10 Fresenius Kabi Usa Llc Levothyroxine liquid formulations
IT201800003615A1 (it) 2018-03-15 2019-09-15 Altergon Sa Formulazioni altamente stabili di ormone tiroideo in capsule molli
US11241382B2 (en) 2019-03-01 2022-02-08 Altergon Sa Administration regimen of compositions of T4 thyroid hormone with high oral absorption
US20230338320A1 (en) 2019-11-22 2023-10-26 Wockhardt Limited Oral film composition comprising levothyroxine

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB876320A (en) 1956-11-08 1961-08-30 Glaxo Lab Ltd Pharmaceutical compositions containing d-3:5-diiodothyronine
US3157574A (en) 1959-05-01 1964-11-17 Smith Kline French Lab Method of reducing cholesterol levels
US3855406A (en) * 1966-09-02 1974-12-17 Boots Co Ltd Thiaxanthene derivatives useful for treating peptic ulcers
US3808332A (en) * 1969-01-27 1974-04-30 Armour Pharma Pharmaceutical compositions containing the reaction product of a tertiary phosphine with thyroxine
US3851051A (en) * 1970-07-17 1974-11-26 Scherer R Corp Soft gelatin capsule containing high water content fill
DE3629386A1 (de) * 1986-08-29 1988-03-03 Scherer Gmbh R P Gelatinekapseln und verfahren zu ihrer herstellung
US4935243A (en) * 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
DE4026600A1 (de) 1990-08-23 1992-02-27 Henning Berlin Gmbh Mittel zur tsh-suppression und behandlung von struma
US5225204A (en) * 1991-11-05 1993-07-06 Chen Jivn Ren Stable dosage of levothyroxine sodium and process of production
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
GB2290965A (en) * 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
DE69518006T2 (de) * 1994-12-16 2000-12-21 Warner Lambert Co Verfahren zur einkapselung von tabletten in eine kapsel und feststoff-dosierungsformen erhaltbar durch dieses verfahren
DE19541128C2 (de) 1995-10-27 1997-11-27 Henning Berlin Gmbh & Co Stabilisierte schilddrüsenhormonhaltige Arzneimittel
US5635209A (en) * 1995-10-31 1997-06-03 Vintage Pharmaceuticals, Inc. Stabilized composition of levothyroxine sodium medication and method for its production
WO1997017951A1 (en) * 1995-11-14 1997-05-22 Knoll Pharmaceutical Company Stabilized thyroid hormone preparations and methods of making same
US6197787B1 (en) 1997-03-03 2001-03-06 Sanofi-Synthelabo Pharmaceutical formulations containing poorly soluble drug substances
DE19821625C1 (de) * 1998-05-15 2000-01-05 Merck Patent Gmbh Pharmazeutische Zubereitung
US6190696B1 (en) * 1998-06-08 2001-02-20 Pieter J. Groenewoud Stabilized thyroxine medications

Also Published As

Publication number Publication date
EP1291021A2 (en) 2003-03-12
ES2254559T3 (es) 2006-06-16
US20030050344A1 (en) 2003-03-13
ITMI20011401A1 (it) 2003-01-02
JP2003081870A (ja) 2003-03-19
DE60207951D1 (de) 2006-01-19
CA2392545C (en) 2012-12-18
DE60207951T2 (de) 2006-08-03
EP1291021B1 (en) 2005-12-14
ATE312621T1 (de) 2005-12-15
CA2392545A1 (en) 2003-01-02
US7723390B2 (en) 2010-05-25
JP5105685B2 (ja) 2012-12-26
DK1291021T3 (da) 2006-04-10
EP1291021A3 (en) 2003-04-16

Similar Documents

Publication Publication Date Title
ITMI20011401A0 (it) Formulazioni farmaceutiche per ormoni tiroidei
NO20033556L (no) Farmasöytiske formuleringer
PT1501534E (pt) Formulacoes farmaceuticas
NO20033384D0 (no) Farmasöytisk formulering
ITTO20010008A0 (it) Formulazione farmaceutica
ATE307571T1 (de) Pharmazeutische formulierung enthaltend bicalutamid
DK1615646T4 (da) Farmaceutiske formuleringer, der indeholder methylnaltrexon
ATE372765T1 (de) Feste pharmazeutische formulierungen mit telmisartan
NO20030627L (no) Hydrogel-drevet medikament doseringsform
FI20011478A (fi) Farmaseuttinen koostumus
AT7729U3 (de) Pharmazeutische zusammensetzungen enthaltend amlodipinmaleat
DE60312049D1 (de) Stabilisierte pharmazeutische zusammensetzung enthaltend einen amorphen wirkstoff
DK1425019T3 (da) Farmaceutisk sammensætning omfattende et androgen
NO20035627D0 (no) Farmasöytisk formulering
ATE324883T1 (de) Pharmazeutische zusammensetzung enthaltend lumiracoxib
FI20022128A (fi) Farmaseuttinen koostumus
ATE350016T1 (de) Bicalutamid enthaltende pharmazeutische zusammensetzung
DE60328119D1 (de) Pharmazeutische zubereitungen enthaltend modafinil
NO20041485L (no) Farmasoytisk formulering omfattende (R)-bicalutamid
DE10291905D2 (de) Pharmazeutische Zusammensetzung
ATE350029T1 (de) Pharmazeutische zusammensetzung enthaltend gamma- butyrobetain
ITMI20011390A0 (it) Formulazioni farmaceutiche per ormoni tiroidei
DE10107261B4 (de) Pharmazeutische Zusammensetzung
FI20012242A0 (fi) Uudet farmaseuttiset yhdisteet
NO20041236L (no) Farmasoytisk formulering