IT9067995A0 - Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione - Google Patents
Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazioneInfo
- Publication number
- IT9067995A0 IT9067995A0 IT67995A IT6799590A IT9067995A0 IT 9067995 A0 IT9067995 A0 IT 9067995A0 IT 67995 A IT67995 A IT 67995A IT 6799590 A IT6799590 A IT 6799590A IT 9067995 A0 IT9067995 A0 IT 9067995A0
- Authority
- IT
- Italy
- Prior art keywords
- antigastrinic
- glutammic
- polycyclic
- bicyclic
- aspartic
- Prior art date
Links
- -1 2-AMINO ADIPIC ACIDS Chemical class 0.000 title 1
- 229920000881 Modified starch Polymers 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/54—Spiro-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/93—Spiro compounds
- C07C2603/94—Spiro compounds containing "free" spiro atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT67995A IT1241029B (it) | 1990-12-11 | 1990-12-11 | Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione |
| DK92900268.1T DK0561863T3 (da) | 1990-12-11 | 1991-12-06 | Amidiske derivater af glutamin-, asparagin- og 2-aminoadipinsyrer med antigastrin-virkning |
| US08/074,818 US5500430A (en) | 1990-12-11 | 1991-12-06 | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids, a process for preparing same, and anti-gastrin composition containing the derivatives |
| PCT/EP1991/002342 WO1992010479A1 (en) | 1990-12-11 | 1991-12-06 | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids with antigastrin activity |
| JP4500365A JPH06503557A (ja) | 1990-12-11 | 1991-12-06 | 抗ガストリン活性を有するグルタミン酸、アスパラギン酸及び２−アミノアジピン酸のアミド誘導体 |
| AU90456/91A AU654312B2 (en) | 1990-12-11 | 1991-12-06 | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids with antigastrin activity |
| EP92900268A EP0561863B1 (en) | 1990-12-11 | 1991-12-06 | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids with antigastrin activity |
| CA002097069A CA2097069A1 (en) | 1990-12-11 | 1991-12-06 | Amidic derivatives of glutamic, aspartic and 2-amino adipic acids with antigastrin activity |
| AT92900268T ATE113583T1 (de) | 1990-12-11 | 1991-12-06 | Amidoderivate von glutamin-, asparagin- und 2- aminoadipinsäuren mit antigastrin-wirkung. |
| ES92900268T ES2064159T3 (es) | 1990-12-11 | 1991-12-06 | Derivados amidicos de los acidos glutamico, aspartico y 2-amino adipico con actividad antigastrina. |
| DE69104996T DE69104996T2 (de) | 1990-12-11 | 1991-12-06 | Amidoderivate von glutamin-, asparagin- und 2-aminoadipinsäuren mit antigastrin-wirkung. |
| IE429191A IE74250B1 (en) | 1990-12-11 | 1991-12-10 | Amidic derivatives of glutamic aspartic and 2-amino adipic acids with antigastrin activity |
| PT99745A PT99745A (pt) | 1990-12-11 | 1991-12-10 | Processo para a preparacao de derivados amidicos biciclicos e policiclicos do acido glutamico do acido aspartico e do acido 2-amino-adipico com actividade antigastrina |
| ZA919762A ZA919762B (en) | 1990-12-11 | 1991-12-11 | Bicyclic and polycyclic amidic derivatives of glutamic,aspartic and 2-amino adipic acids with antigastrin activity and a method for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT67995A IT1241029B (it) | 1990-12-11 | 1990-12-11 | Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9067995A0 true IT9067995A0 (it) | 1990-12-11 |
| IT9067995A1 IT9067995A1 (it) | 1992-06-12 |
| IT1241029B IT1241029B (it) | 1993-12-27 |
Family
ID=11307048
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT67995A IT1241029B (it) | 1990-12-11 | 1990-12-11 | Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5500430A (it) |
| EP (1) | EP0561863B1 (it) |
| JP (1) | JPH06503557A (it) |
| AT (1) | ATE113583T1 (it) |
| AU (1) | AU654312B2 (it) |
| CA (1) | CA2097069A1 (it) |
| DE (1) | DE69104996T2 (it) |
| DK (1) | DK0561863T3 (it) |
| ES (1) | ES2064159T3 (it) |
| IE (1) | IE74250B1 (it) |
| IT (1) | IT1241029B (it) |
| PT (1) | PT99745A (it) |
| WO (1) | WO1992010479A1 (it) |
| ZA (1) | ZA919762B (it) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE912285A1 (en) * | 1990-07-12 | 1992-01-15 | Black James Foundation | Amino acid derivatives |
| IT1264765B1 (it) * | 1993-03-10 | 1996-10-04 | Rotta Research Lab | Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la |
| IT1261255B (it) * | 1993-09-09 | 1996-05-09 | Rotta Research Lab | Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico. |
| IT1276462B1 (it) * | 1995-07-03 | 1997-10-31 | Rotta Research Lab | Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico |
| WO1997044341A1 (en) * | 1996-05-17 | 1997-11-27 | Rotta Research Laboratorium S.P.A. | Cyclic polyamides of glutamic acid and aspartic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use |
| WO1997045415A1 (en) * | 1996-05-28 | 1997-12-04 | Rotta Research Laboratorium S.P.A. | Polyamide derivatives or ornithine, lysine and analogous substances with cck-b and gastrin-antagonistic activity |
| IT1286141B1 (it) * | 1996-07-02 | 1998-07-07 | Rotta Research Lab | Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico. |
| US6365128B1 (en) * | 1998-12-18 | 2002-04-02 | Medical Defence Technologies, Llc | Monitoring gastrointestinal function to guide care of high risk patients |
| EP2720605B1 (en) | 2011-06-14 | 2020-03-11 | Gravitas Medical Inc. | Apparatus for guiding medical care based on detected gastric function |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ212436A (en) * | 1984-06-25 | 1989-04-26 | Rotta Research Lab | D,l-glutamic and d,l-aspartic acid derivatives and pharmaceutical compositions |
| FR2643371B1 (fr) * | 1989-02-17 | 1993-11-05 | Roussel Uclaf | Nouveaux derives de l'acide 2-amino pentanedioique, leur procede de preparation et leur application comme medicaments |
| IT1238664B (it) * | 1989-11-02 | 1993-09-01 | Rotta Research Lab | Derivati degli acidi glutammico ed aspartico ad attivita' antigastrinica e procedimento per la loro preparazione |
-
1990
- 1990-12-11 IT IT67995A patent/IT1241029B/it active IP Right Grant
-
1991
- 1991-12-06 US US08/074,818 patent/US5500430A/en not_active Expired - Fee Related
- 1991-12-06 DK DK92900268.1T patent/DK0561863T3/da active
- 1991-12-06 CA CA002097069A patent/CA2097069A1/en not_active Abandoned
- 1991-12-06 JP JP4500365A patent/JPH06503557A/ja active Pending
- 1991-12-06 ES ES92900268T patent/ES2064159T3/es not_active Expired - Lifetime
- 1991-12-06 AT AT92900268T patent/ATE113583T1/de active
- 1991-12-06 DE DE69104996T patent/DE69104996T2/de not_active Expired - Fee Related
- 1991-12-06 AU AU90456/91A patent/AU654312B2/en not_active Ceased
- 1991-12-06 EP EP92900268A patent/EP0561863B1/en not_active Expired - Lifetime
- 1991-12-06 WO PCT/EP1991/002342 patent/WO1992010479A1/en active IP Right Grant
- 1991-12-10 PT PT99745A patent/PT99745A/pt not_active Application Discontinuation
- 1991-12-10 IE IE429191A patent/IE74250B1/en not_active IP Right Cessation
- 1991-12-11 ZA ZA919762A patent/ZA919762B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE113583T1 (de) | 1994-11-15 |
| US5500430A (en) | 1996-03-19 |
| EP0561863A1 (en) | 1993-09-29 |
| DK0561863T3 (da) | 1994-11-28 |
| DE69104996T2 (de) | 1995-04-20 |
| AU9045691A (en) | 1992-07-08 |
| DE69104996D1 (de) | 1994-12-08 |
| PT99745A (pt) | 1992-12-31 |
| CA2097069A1 (en) | 1992-06-12 |
| JPH06503557A (ja) | 1994-04-21 |
| AU654312B2 (en) | 1994-11-03 |
| ZA919762B (en) | 1992-09-30 |
| IT1241029B (it) | 1993-12-27 |
| WO1992010479A1 (en) | 1992-06-25 |
| IT9067995A1 (it) | 1992-06-12 |
| EP0561863B1 (en) | 1994-11-02 |
| ES2064159T3 (es) | 1995-01-16 |
| IE74250B1 (en) | 1997-07-16 |
| IE914291A1 (en) | 1992-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971231 |