IT9019324A1 - Derivati del bilobalide, loro usi e formulazioni che li contegono - Google Patents

Derivati del bilobalide, loro usi e formulazioni che li contegono

Info

Publication number
IT9019324A1
IT9019324A1 IT019324A IT1932490A IT9019324A1 IT 9019324 A1 IT9019324 A1 IT 9019324A1 IT 019324 A IT019324 A IT 019324A IT 1932490 A IT1932490 A IT 1932490A IT 9019324 A1 IT9019324 A1 IT 9019324A1
Authority
IT
Italy
Prior art keywords
bilobalide
inflammatory
treatment
disorders associated
formulations
Prior art date
Application number
IT019324A
Other languages
English (en)
Other versions
IT9019324A0 (it
IT1238684B (it
Inventor
Gabriele Fontana
Giuseppe Mustich
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of IT9019324A0 publication Critical patent/IT9019324A0/it
Priority to IT19324A priority Critical patent/IT1238684B/it
Priority to US07/651,598 priority patent/US5202313A/en
Priority to EP91101425A priority patent/EP0441279B1/en
Priority to DK91101425.6T priority patent/DK0441279T3/da
Priority to ES91101425T priority patent/ES2066239T3/es
Priority to AT91101425T priority patent/ATE115585T1/de
Priority to DE69105767T priority patent/DE69105767T2/de
Priority to CA002035951A priority patent/CA2035951C/en
Priority to JP3102195A priority patent/JP3036881B2/ja
Priority to KR1019910002192A priority patent/KR0170773B1/ko
Publication of IT9019324A1 publication Critical patent/IT9019324A1/it
Application granted granted Critical
Publication of IT1238684B publication Critical patent/IT1238684B/it
Priority to HK160795A priority patent/HK160795A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT19324A 1990-02-09 1990-02-09 Derivati del bilobalide,loro usi e formulazioni che li contegono IT1238684B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT19324A IT1238684B (it) 1990-02-09 1990-02-09 Derivati del bilobalide,loro usi e formulazioni che li contegono
US07/651,598 US5202313A (en) 1990-02-09 1991-02-06 Bilobalide derivatives, their applications and formulations containing them
DE69105767T DE69105767T2 (de) 1990-02-09 1991-02-07 Bilobalid-Phospholipid-Komplexe, ihre Anwendung und Zusammensetzungen enthaltend diese.
DK91101425.6T DK0441279T3 (da) 1990-02-09 1991-02-07 Bilobalid-phospholipid-komplekser, deres anvendelse og sammensætninger, der indeholder dem
ES91101425T ES2066239T3 (es) 1990-02-09 1991-02-07 Complejos fosfolipidicos de bilobalido, sus aplicaciones y formulados que los contienen.
AT91101425T ATE115585T1 (de) 1990-02-09 1991-02-07 Bilobalid-phospholipid-komplexe, ihre anwendung und zusammensetzungen enthaltend diese.
EP91101425A EP0441279B1 (en) 1990-02-09 1991-02-07 Bilobalide phospholipide complexes, their applications and formulations containing them
CA002035951A CA2035951C (en) 1990-02-09 1991-02-07 Bilobalide derivatives, their applications and formulations containing them
JP3102195A JP3036881B2 (ja) 1990-02-09 1991-02-07 ビロバリデ誘導体、この用途及びこれを含有する薬剤組成物
KR1019910002192A KR0170773B1 (ko) 1990-02-09 1991-02-07 빌로발리드 유도체, 그 용도 및 이를 함유한 제제
HK160795A HK160795A (en) 1990-02-09 1995-10-12 Bilobalide phospholipide complexes their applications and formulations containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19324A IT1238684B (it) 1990-02-09 1990-02-09 Derivati del bilobalide,loro usi e formulazioni che li contegono

Publications (3)

Publication Number Publication Date
IT9019324A0 IT9019324A0 (it) 1990-02-09
IT9019324A1 true IT9019324A1 (it) 1991-08-09
IT1238684B IT1238684B (it) 1993-09-01

Family

ID=11156741

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19324A IT1238684B (it) 1990-02-09 1990-02-09 Derivati del bilobalide,loro usi e formulazioni che li contegono

Country Status (11)

Country Link
US (1) US5202313A (it)
EP (1) EP0441279B1 (it)
JP (1) JP3036881B2 (it)
KR (1) KR0170773B1 (it)
AT (1) ATE115585T1 (it)
CA (1) CA2035951C (it)
DE (1) DE69105767T2 (it)
DK (1) DK0441279T3 (it)
ES (1) ES2066239T3 (it)
HK (1) HK160795A (it)
IT (1) IT1238684B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
DE540767T1 (de) * 1991-11-04 2001-10-25 Ruth-Maria Korth Behandlung und Vorbeugung von von erhöhten Lyso-PAF-Spiegel mediierten mentalen Erkrankungen mit PAF-Antagonisten
DE540766T1 (de) * 1991-11-04 2002-11-28 Ruth-Maria Korth Behandlung von Eosinophil-mediierten Erkrankungen mit PAF-Antagonisten, und Verfahren zur Bestimmung deren Effektivität.
GB9202993D0 (en) * 1992-02-13 1992-03-25 Indena Spa Novel pharmaceutical uses of bilobalide and derivatives thereof and pharmaceutical compositions adapted for such use
GB9205670D0 (en) * 1992-03-16 1992-04-29 Indena Spa New derivatives of physostigmine,their use and pharmaceutical formulations containing them
US5456912A (en) * 1993-12-28 1995-10-10 The Regents Of The University Of California Non-methylene interrupted fatty acids as immunomodulators
US6379714B1 (en) 1995-04-14 2002-04-30 Pharmaprint, Inc. Pharmaceutical grade botanical drugs
WO1999064028A1 (en) * 1998-06-11 1999-12-16 Societe De Conseils De Recherches Et D'applications Scientifiques Sas Protecting neurons from ischemia
US7494643B2 (en) * 2003-07-22 2009-02-24 Rendon Marta I Method and topical composition for the treatment of hyperpigmented skin
ES2323864T3 (es) 2004-01-29 2009-07-27 Indena Spa Uso de complejos de ginkgo para la potenciacion de las funciones cognitivas y alivio de la fatiga mental.
ITMI20060136A1 (it) * 2006-01-27 2007-07-28 Pharmextracta S R L Composizioni a base di derivati della ginkgo biloba per il trattamento di condizioni asmatiche e allergiche
ITMI20071492A1 (it) 2007-07-24 2009-01-25 S I I T Srl Servizio Internazi "composizioni per il trattamento e la prevenzione di condizioni di vertigine e acufeni comprendenti citicolina, estratto di ginkgo biloba e flavoni dimerici di ginkgo biloba"
IT1397386B1 (it) 2010-01-12 2013-01-10 Indena Spa Composizioni a base di estratti di andrographis paniculata combinati con estratti di ginkgo biloba complessati con fosfolipidi e loro uso.
IT1402672B1 (it) 2010-11-08 2013-09-13 Medestea Biotech S P A Composizioni comprendenti principi attivi di origine vegetale associati o meno a promotori e/o protettori di ossido nitrico per il trattamento e la prevenzione dei deficit erettili e dell' impotenza e per il potenziamento della performance sportiva
ITTO20110901A1 (it) 2011-10-10 2013-04-11 Medestea Biotech S P A Composizione sinergica per la prevenzione ed il trattamento di disturbi connessi all'invecchiamento
CN109851634B (zh) * 2018-12-25 2020-12-22 华东师范大学 手性单膦配体Yu-Phos及其全构型的制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3338995A1 (de) * 1983-10-27 1985-05-09 Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe Bilobalid enthaltende arzneimittel
DD213672A1 (de) * 1983-03-04 1984-09-19 Akad Wissenschaften Ddr Verfahren zur herstellung von gibberellin-derivaten mit 13,16-anneliertem oxathiaphospholan-ring
IT1215291B (it) * 1985-07-17 1990-01-31 Inverni Della Beffa Spa Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.
IT1201149B (it) * 1987-01-14 1989-01-27 Indena Spa Complessi di bioflavonoidi con fosfolipidi,loro preparazione,uso e composizioni farmaceutici e cosmetiche
IT1203515B (it) * 1987-02-26 1989-02-15 Indena Spa Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono
JPH0231646A (ja) * 1988-07-21 1990-02-01 Daicel Chem Ind Ltd イチョウ抽出物入りチョコレート
JPH0231648A (ja) * 1988-07-21 1990-02-01 Daicel Chem Ind Ltd イチョウ抽出物入りチューインガム

Also Published As

Publication number Publication date
JPH06145174A (ja) 1994-05-24
IT9019324A0 (it) 1990-02-09
KR910015308A (ko) 1991-09-30
HK160795A (en) 1995-10-20
CA2035951A1 (en) 1991-08-10
JP3036881B2 (ja) 2000-04-24
US5202313A (en) 1993-04-13
ATE115585T1 (de) 1994-12-15
ES2066239T3 (es) 1995-03-01
CA2035951C (en) 2001-07-31
EP0441279B1 (en) 1994-12-14
EP0441279A1 (en) 1991-08-14
DE69105767T2 (de) 1995-04-27
IT1238684B (it) 1993-09-01
DE69105767D1 (de) 1995-01-26
KR0170773B1 (ko) 1999-03-30
DK0441279T3 (da) 1995-05-08

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950228