IT8920134A0 - Processo di risoluzione di intermedi utili per la preparazione di 1,5 benzotiazepine. - Google Patents

Processo di risoluzione di intermedi utili per la preparazione di 1,5 benzotiazepine.

Info

Publication number
IT8920134A0
IT8920134A0 IT8920134A IT2013489A IT8920134A0 IT 8920134 A0 IT8920134 A0 IT 8920134A0 IT 8920134 A IT8920134 A IT 8920134A IT 2013489 A IT2013489 A IT 2013489A IT 8920134 A0 IT8920134 A0 IT 8920134A0
Authority
IT
Italy
Prior art keywords
benzothiazepines
preparation
resolution process
intermediate useful
useful
Prior art date
Application number
IT8920134A
Other languages
English (en)
Other versions
IT1230057B (it
Inventor
Dario Tentorio
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of IT8920134A0 publication Critical patent/IT8920134A0/it
Priority to IT8920134A priority Critical patent/IT1230057B/it
Priority to US07/504,860 priority patent/US5144025A/en
Priority to EP95103953A priority patent/EP0669327B1/en
Priority to ES90107048T priority patent/ES2106724T3/es
Priority to DK90107048.2T priority patent/DK0392543T3/da
Priority to ES95103953T priority patent/ES2138100T3/es
Priority to DK95103953T priority patent/DK0669327T3/da
Priority to DE69031187T priority patent/DE69031187T2/de
Priority to AT90107048T priority patent/ATE156484T1/de
Priority to DE69033315T priority patent/DE69033315T2/de
Priority to AT95103953T priority patent/ATE185343T1/de
Priority to EP90107048A priority patent/EP0392543B1/en
Priority to JP2099140A priority patent/JP2979237B2/ja
Application granted granted Critical
Publication of IT1230057B publication Critical patent/IT1230057B/it
Priority to GR970402823T priority patent/GR3025188T3/el
Priority to GR990403114T priority patent/GR3032027T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IT8920134A 1989-04-13 1989-04-13 Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine IT1230057B (it)

Priority Applications (15)

Application Number Priority Date Filing Date Title
IT8920134A IT1230057B (it) 1989-04-13 1989-04-13 Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
US07/504,860 US5144025A (en) 1989-04-13 1990-04-05 Process for the resolution of intermediates useful in the preparation of 1,5-benzothiazepines
DK95103953T DK0669327T3 (da) 1989-04-13 1990-04-12 Fremgangsmåde til fremstilling af 1,5-benzothiazepiner ved ringslutning af aminoestere
DE69033315T DE69033315T2 (de) 1989-04-13 1990-04-12 Verfahren zur Herstellung von 1,5-Benzothiazepinen durch Ringschluss von Aminoestern
DK90107048.2T DK0392543T3 (da) 1989-04-13 1990-04-12 Fremgangsmåde til opløsning af mellemprodukter, der er anvendelige ved fremstilling af 1,5-benzothiazepiner
ES95103953T ES2138100T3 (es) 1989-04-13 1990-04-12 Procedimiento para la preparacion de 1,5-benzotiazepinas por ciclizacion de esteres aminicos.
EP95103953A EP0669327B1 (en) 1989-04-13 1990-04-12 Process for the preparation of 1,5-benzothiazepines by ring closure of amino esters
DE69031187T DE69031187T2 (de) 1989-04-13 1990-04-12 Verfahren für die Racemattrennung von Zwischenprodukten, die bei der Herstellung von 1,5-Benzothiazepinen verwendbar sind
AT90107048T ATE156484T1 (de) 1989-04-13 1990-04-12 Verfahren für die racemattrennung von zwischenprodukten, die bei der herstellung von 1,5-benzothiazepinen verwendbar sind
ES90107048T ES2106724T3 (es) 1989-04-13 1990-04-12 Procedimiento para la resolucion de intermedios utiles en la preparacion de 1,5-benzotiazepinas.
AT95103953T ATE185343T1 (de) 1989-04-13 1990-04-12 Verfahren zur herstellung von 1,5- benzothiazepinen durch ringschluss von aminoestern
EP90107048A EP0392543B1 (en) 1989-04-13 1990-04-12 Process for the resolution of intermediates useful in the preparation of 1,5-benzothiazepines
JP2099140A JP2979237B2 (ja) 1989-04-13 1990-04-13 １，５―ベンゾチアゼピン類合成中間体の分割方法
GR970402823T GR3025188T3 (en) 1989-04-13 1997-10-29 Process for the resolution of intermediates useful in the preparation of 1,5-benzothiazepines
GR990403114T GR3032027T3 (en) 1989-04-13 1999-12-02 Process for the preparation of 1,5-benzothiazepines by ring closure of amino esters.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920134A IT1230057B (it) 1989-04-13 1989-04-13 Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine

Publications (2)

Publication Number Publication Date
IT8920134A0 true IT8920134A0 (it) 1989-04-13
IT1230057B IT1230057B (it) 1991-09-27

Family

ID=11164095

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920134A IT1230057B (it) 1989-04-13 1989-04-13 Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine

Country Status (9)

Country Link
US (1) US5144025A (it)
EP (2) EP0669327B1 (it)
JP (1) JP2979237B2 (it)
AT (2) ATE185343T1 (it)
DE (2) DE69033315T2 (it)
DK (2) DK0392543T3 (it)
ES (2) ES2106724T3 (it)
GR (2) GR3025188T3 (it)
IT (1) IT1230057B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1234387B (it) * 1989-07-12 1992-05-18 Zambon Spa Processo di purificazione di intermedi utili nella preparazione del diltiazem
US4963671A (en) * 1989-11-20 1990-10-16 E. R. Squibb & Sons, Inc. Process for resolving chiral intermediates used in making calcium channel blockers
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法
EP0778272B1 (en) * 1995-12-05 1998-12-23 Tanabe Seiyaku Co., Ltd. Optically active benzothiazepine compounds and process for preparing the same
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
DE10142564A1 (de) 2000-09-30 2002-04-11 Zeiss Carl Stativ
US20030119908A1 (en) * 2001-12-21 2003-06-26 Zambon Group S.P.A. Stable gabapentin compositions
CN101532094B (zh) * 2008-03-11 2010-07-28 江西稀有稀土金属钨业集团有限公司 从钙和镁杂质含量高的酸性原料体系中全程萃取分离得到镍和钴的工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
SE449611B (sv) * 1982-07-09 1987-05-11 Tanabe Seiyaku Co Sett att framstella 1,5-bensotiazepinderivat
IT1152721B (it) * 1982-10-15 1987-01-07 Luso Farmaco Inst Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4594342A (en) * 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
GB2167063A (en) * 1984-11-17 1986-05-21 Tanabe Seiyaku Co 6 or 9-chloro-1, 5-benzothiazepine derivatives
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
ZA893392B (en) * 1988-05-24 1990-01-31 Hoffmann La Roche Process for the manufacture of optically active naphthothiazepinones
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
ATE116643T1 (de) * 1989-04-28 1995-01-15 Tanabe Seiyaku Co Verfahren zur herstellung von 1,5- benzothiazepinderivaten.
US4963671A (en) * 1989-11-20 1990-10-16 E. R. Squibb & Sons, Inc. Process for resolving chiral intermediates used in making calcium channel blockers
JPH085869B2 (ja) * 1990-03-08 1996-01-24 田辺製薬株式会社 １，５−ベンゾチアゼピン誘導体の製法

Also Published As

Publication number Publication date
GR3025188T3 (en) 1998-02-27
ES2138100T3 (es) 2000-01-01
GR3032027T3 (en) 2000-03-31
EP0669327B1 (en) 1999-10-06
DE69031187D1 (de) 1997-09-11
IT1230057B (it) 1991-09-27
DE69033315D1 (de) 1999-11-11
ATE185343T1 (de) 1999-10-15
US5144025A (en) 1992-09-01
JPH03115273A (ja) 1991-05-16
EP0392543B1 (en) 1997-08-06
DK0392543T3 (da) 1997-09-15
JP2979237B2 (ja) 1999-11-15
DK0669327T3 (da) 2000-04-10
ATE156484T1 (de) 1997-08-15
EP0392543A1 (en) 1990-10-17
DE69031187T2 (de) 1998-01-22
ES2106724T3 (es) 1997-11-16
DE69033315T2 (de) 2000-04-13
EP0669327A1 (en) 1995-08-30

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970311