ATE156484T1 - Verfahren für die racemattrennung von zwischenprodukten, die bei der herstellung von 1,5-benzothiazepinen verwendbar sind - Google Patents
Verfahren für die racemattrennung von zwischenprodukten, die bei der herstellung von 1,5-benzothiazepinen verwendbar sindInfo
- Publication number
- ATE156484T1 ATE156484T1 AT90107048T AT90107048T ATE156484T1 AT E156484 T1 ATE156484 T1 AT E156484T1 AT 90107048 T AT90107048 T AT 90107048T AT 90107048 T AT90107048 T AT 90107048T AT E156484 T1 ATE156484 T1 AT E156484T1
- Authority
- AT
- Austria
- Prior art keywords
- racemat
- benzothiazepines
- separation
- production
- intermediate products
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8920134A IT1230057B (it) | 1989-04-13 | 1989-04-13 | Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE156484T1 true ATE156484T1 (de) | 1997-08-15 |
Family
ID=11164095
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95103953T ATE185343T1 (de) | 1989-04-13 | 1990-04-12 | Verfahren zur herstellung von 1,5- benzothiazepinen durch ringschluss von aminoestern |
AT90107048T ATE156484T1 (de) | 1989-04-13 | 1990-04-12 | Verfahren für die racemattrennung von zwischenprodukten, die bei der herstellung von 1,5-benzothiazepinen verwendbar sind |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95103953T ATE185343T1 (de) | 1989-04-13 | 1990-04-12 | Verfahren zur herstellung von 1,5- benzothiazepinen durch ringschluss von aminoestern |
Country Status (9)
Country | Link |
---|---|
US (1) | US5144025A (de) |
EP (2) | EP0669327B1 (de) |
JP (1) | JP2979237B2 (de) |
AT (2) | ATE185343T1 (de) |
DE (2) | DE69031187T2 (de) |
DK (2) | DK0392543T3 (de) |
ES (2) | ES2106724T3 (de) |
GR (2) | GR3025188T3 (de) |
IT (1) | IT1230057B (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1234387B (it) * | 1989-07-12 | 1992-05-18 | Zambon Spa | Processo di purificazione di intermedi utili nella preparazione del diltiazem |
US4963671A (en) * | 1989-11-20 | 1990-10-16 | E. R. Squibb & Sons, Inc. | Process for resolving chiral intermediates used in making calcium channel blockers |
JPH085869B2 (ja) * | 1990-03-08 | 1996-01-24 | 田辺製薬株式会社 | 1,5−ベンゾチアゼピン誘導体の製法 |
EP0778272B1 (de) * | 1995-12-05 | 1998-12-23 | Tanabe Seiyaku Co., Ltd. | Optisch aktive Benzothiazepinderivate und Verfahren zu ihrer Herstellung |
IT1295376B1 (it) * | 1997-10-22 | 1999-05-12 | Zambon Spa | Processo per il riciclo di un sottoprodotto della sintesi del diltiazem |
DE20114343U1 (de) | 2000-09-30 | 2001-11-29 | Carl Zeiss, 89518 Heidenheim | Stativ |
US20030119908A1 (en) * | 2001-12-21 | 2003-06-26 | Zambon Group S.P.A. | Stable gabapentin compositions |
CN101532094B (zh) * | 2008-03-11 | 2010-07-28 | 江西稀有稀土金属钨业集团有限公司 | 从钙和镁杂质含量高的酸性原料体系中全程萃取分离得到镍和钴的工艺 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1236467A (en) * | 1967-10-28 | 1971-06-23 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
IT1152721B (it) * | 1982-10-15 | 1987-01-07 | Luso Farmaco Inst | Risoluzione ottica dell'acido dl-alfa-2-idrossi-3-(4-metossifenil)-3-(2-amminofeniltio)propionico |
US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
US4594342A (en) * | 1984-04-10 | 1986-06-10 | Tanabe Seiyaku Co., Ltd. | 1,5-benzothiazepine derivative |
GB2167063A (en) * | 1984-11-17 | 1986-05-21 | Tanabe Seiyaku Co | 6 or 9-chloro-1, 5-benzothiazepine derivatives |
EP0322779A3 (de) * | 1987-12-29 | 1991-05-08 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzolaktam-Verbindungen und deren pharmazeutische Verwendungen |
ZA893392B (en) * | 1988-05-24 | 1990-01-31 | Hoffmann La Roche | Process for the manufacture of optically active naphthothiazepinones |
FR2641535B1 (fr) * | 1989-01-11 | 1991-03-15 | Synthelabo | Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4 |
ES2069003T3 (es) * | 1989-04-28 | 1995-05-01 | Tanabe Seiyaku Co | Procedimiento para preparar derivados de 1,5-benzotiazepina. |
US4963671A (en) * | 1989-11-20 | 1990-10-16 | E. R. Squibb & Sons, Inc. | Process for resolving chiral intermediates used in making calcium channel blockers |
JPH085869B2 (ja) * | 1990-03-08 | 1996-01-24 | 田辺製薬株式会社 | 1,5−ベンゾチアゼピン誘導体の製法 |
-
1989
- 1989-04-13 IT IT8920134A patent/IT1230057B/it active
-
1990
- 1990-04-05 US US07/504,860 patent/US5144025A/en not_active Expired - Lifetime
- 1990-04-12 EP EP95103953A patent/EP0669327B1/de not_active Expired - Lifetime
- 1990-04-12 EP EP90107048A patent/EP0392543B1/de not_active Expired - Lifetime
- 1990-04-12 DK DK90107048.2T patent/DK0392543T3/da active
- 1990-04-12 DE DE69031187T patent/DE69031187T2/de not_active Expired - Fee Related
- 1990-04-12 DK DK95103953T patent/DK0669327T3/da active
- 1990-04-12 AT AT95103953T patent/ATE185343T1/de not_active IP Right Cessation
- 1990-04-12 AT AT90107048T patent/ATE156484T1/de not_active IP Right Cessation
- 1990-04-12 ES ES90107048T patent/ES2106724T3/es not_active Expired - Lifetime
- 1990-04-12 DE DE69033315T patent/DE69033315T2/de not_active Expired - Fee Related
- 1990-04-12 ES ES95103953T patent/ES2138100T3/es not_active Expired - Lifetime
- 1990-04-13 JP JP2099140A patent/JP2979237B2/ja not_active Expired - Lifetime
-
1997
- 1997-10-29 GR GR970402823T patent/GR3025188T3/el unknown
-
1999
- 1999-12-02 GR GR990403114T patent/GR3032027T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2138100T3 (es) | 2000-01-01 |
JP2979237B2 (ja) | 1999-11-15 |
GR3025188T3 (en) | 1998-02-27 |
GR3032027T3 (en) | 2000-03-31 |
EP0669327B1 (de) | 1999-10-06 |
EP0669327A1 (de) | 1995-08-30 |
IT1230057B (it) | 1991-09-27 |
DE69031187D1 (de) | 1997-09-11 |
DK0392543T3 (da) | 1997-09-15 |
JPH03115273A (ja) | 1991-05-16 |
DE69033315D1 (de) | 1999-11-11 |
ATE185343T1 (de) | 1999-10-15 |
DK0669327T3 (da) | 2000-04-10 |
ES2106724T3 (es) | 1997-11-16 |
US5144025A (en) | 1992-09-01 |
EP0392543B1 (de) | 1997-08-06 |
DE69031187T2 (de) | 1998-01-22 |
IT8920134A0 (it) | 1989-04-13 |
DE69033315T2 (de) | 2000-04-13 |
EP0392543A1 (de) | 1990-10-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |