IT7927856A0 - Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par. quadra aperta par. quadra 1,4 chiusa par.quadra tiazine otiazepine. - Google Patents

Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par. quadra aperta par. quadra 1,4 chiusa par.quadra tiazine otiazepine.

Info

Publication number
IT7927856A0
IT7927856A0 IT7927856A IT2785679A IT7927856A0 IT 7927856 A0 IT7927856 A0 IT 7927856A0 IT 7927856 A IT7927856 A IT 7927856A IT 2785679 A IT2785679 A IT 2785679A IT 7927856 A0 IT7927856 A0 IT 7927856A0
Authority
IT
Italy
Prior art keywords
par
quadra
closed
open square
othiazepines
Prior art date
Application number
IT7927856A
Other languages
English (en)
Other versions
IT1127282B (it
Inventor
Miguel A Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT7927856A0 publication Critical patent/IT7927856A0/it
Application granted granted Critical
Publication of IT1127282B publication Critical patent/IT1127282B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
IT27856/79A 1978-12-07 1979-12-04 Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par.quadra aperta par.quadra 1,4 chiusa par.quadra tiazine otiazepine IT1127282B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/967,335 US4225495A (en) 1978-12-07 1978-12-07 Pyrrolo or pyrido [2,1-c][1,4] thiazines or thiazepines

Publications (2)

Publication Number Publication Date
IT7927856A0 true IT7927856A0 (it) 1979-12-04
IT1127282B IT1127282B (it) 1986-05-21

Family

ID=25512648

Family Applications (1)

Application Number Title Priority Date Filing Date
IT27856/79A IT1127282B (it) 1978-12-07 1979-12-04 Pirrolo oppure pirido aperta par.quadra 2,1-c chiusa par.quadra aperta par.quadra 1,4 chiusa par.quadra tiazine otiazepine

Country Status (18)

Country Link
US (1) US4225495A (it)
JP (1) JPS5581886A (it)
AU (1) AU532228B2 (it)
BE (1) BE880480A (it)
CA (1) CA1126728A (it)
CH (1) CH643268A5 (it)
DE (1) DE2949179A1 (it)
DK (1) DK520279A (it)
FR (2) FR2443468A1 (it)
GB (1) GB2036743B (it)
HU (2) HU182755B (it)
IE (1) IE49123B1 (it)
IT (1) IT1127282B (it)
LU (1) LU81956A1 (it)
NL (1) NL7908618A (it)
NO (1) NO793983L (it)
SE (2) SE446737B (it)
ZA (1) ZA796288B (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692458A (en) * 1980-03-05 1987-09-08 University Of Miami Anti-hypertensive agents
US4385180A (en) * 1980-07-01 1983-05-24 American Home Products Corporation 10,10a-Dihydro-1H-thiozino[4,3-a,]-indole-1,4(3H)-diones
US4352753A (en) * 1980-08-11 1982-10-05 American Home Products Corporation 3-[[(2,3-Dihydro-1H-indol-2-yl)carbonyl]thio]propanoic (and acetic) acids as intermediates
US4415496A (en) * 1981-03-23 1983-11-15 Merck & Co., Inc. Bicyclic lactams
US4661479A (en) * 1982-02-19 1987-04-28 Merck And Co., Inc. Bicyclic lactams as antihypertensives
US4617301A (en) * 1983-06-22 1986-10-14 Merck & Co., Inc. Sulfoxide and sulfone derivatives of bicyclic lactams as antihypertensives
US5508272A (en) * 1993-06-15 1996-04-16 Bristol-Myers Squibb Company Compounds containing a fused bicycle ring and processes therefor
US5616775A (en) * 1994-05-05 1997-04-01 Bristol-Myers Squibb Co. Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5587375A (en) * 1995-02-17 1996-12-24 Bristol-Myers Squibb Company Azepinone compounds useful in the inhibition of ACE and NEP
US5877313A (en) * 1995-05-17 1999-03-02 Bristol-Myers Squibb Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP
US5635504A (en) * 1995-06-07 1997-06-03 Bristol-Myers Squibb Co. Diazepine containing dual action inhibitors
US5650408A (en) * 1995-06-07 1997-07-22 Karanewsky; Donald S. Thiazolo benzazepine containing dual action inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891000A (en) * 1953-09-23 1959-06-16 Exxon Research Engineering Co Process for feeding heavy oils into conversion systems
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4154935A (en) * 1978-02-21 1979-05-15 E. R. Squibb & Sons, Inc. Halogen substituted mercaptoacylamino acids
JPS5576888A (en) * 1978-12-04 1980-06-10 Yoshitomi Pharmaceut Ind Ltd Bicyclic hetero compound and its preparation

Also Published As

Publication number Publication date
FR2443468A1 (fr) 1980-07-04
AU532228B2 (en) 1983-09-22
FR2445318A1 (fr) 1980-07-25
US4225495A (en) 1980-09-30
HU182755B (en) 1984-03-28
FR2445318B1 (it) 1983-04-22
SE452458B (sv) 1987-11-30
DK520279A (da) 1980-06-08
IT1127282B (it) 1986-05-21
JPS5581886A (en) 1980-06-20
GB2036743B (en) 1982-11-24
IE49123B1 (en) 1985-08-07
SE8405123L (sv) 1984-10-12
AU5314479A (en) 1980-06-12
LU81956A1 (fr) 1980-04-22
HU179342B (en) 1982-10-28
IE792329L (en) 1980-06-07
GB2036743A (en) 1980-07-02
SE7910072L (sv) 1980-06-08
DE2949179A1 (de) 1980-06-26
CA1126728A (en) 1982-06-29
CH643268A5 (de) 1984-05-30
FR2443468B1 (it) 1983-04-22
SE446737B (sv) 1986-10-06
NO793983L (no) 1980-06-10
NL7908618A (nl) 1980-06-10
BE880480A (fr) 1980-06-06
ZA796288B (en) 1980-11-26
SE8405123D0 (sv) 1984-10-12

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961227