IT7868372A0 - Derivati della 1,2,3,4,6,7-esaidro 11b alfa h-benzo [a] chinolizina eprocedimento per la sua preparazione - Google Patents
Derivati della 1,2,3,4,6,7-esaidro 11b alfa h-benzo [a] chinolizina eprocedimento per la sua preparazioneInfo
- Publication number
- IT7868372A0 IT7868372A0 IT7868372A IT6837278A IT7868372A0 IT 7868372 A0 IT7868372 A0 IT 7868372A0 IT 7868372 A IT7868372 A IT 7868372A IT 6837278 A IT6837278 A IT 6837278A IT 7868372 A0 IT7868372 A0 IT 7868372A0
- Authority
- IT
- Italy
- Prior art keywords
- quinolizine
- alfa
- hexahydro
- benzo
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
- C07D455/06—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU77CI1751A HU175890B (en) | 1977-06-15 | 1977-06-15 | Process for producing new 1,2,3,4,6,7-hexahydro-11-b-alpha-benzo-square bracket-a-square brecket closed-quinolyzine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7868372A0 true IT7868372A0 (it) | 1978-06-13 |
| IT1203186B IT1203186B (it) | 1989-02-15 |
Family
ID=10994657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT68372/78A IT1203186B (it) | 1977-06-15 | 1978-06-13 | Derivati della 1,2,3,4,6,7-esaidro 11b alfa h-benzo (a) chinolizina e procedimento per la sua preparazione |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4193998A (it) |
| JP (1) | JPS545999A (it) |
| AT (1) | AT363939B (it) |
| DE (1) | DE2824905A1 (it) |
| ES (1) | ES470787A1 (it) |
| FI (1) | FI65245C (it) |
| FR (1) | FR2394546A1 (it) |
| GB (1) | GB2000135B (it) |
| HU (1) | HU175890B (it) |
| IT (1) | IT1203186B (it) |
| NL (1) | NL7800024A (it) |
| SU (1) | SU719499A3 (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4992446A (en) * | 1989-09-05 | 1991-02-12 | G. D. Searle & Co. | Tricyclic quinolizine amides |
| AU2575797A (en) * | 1996-04-19 | 1997-11-12 | Nippon Shinyaku Co. Ltd. | Benzoquinolizine derivatives and medicinal compositions |
| US7897768B2 (en) * | 2007-06-08 | 2011-03-01 | General Electric Company | Method for making tetrabenazine compounds |
| EP2214721A2 (en) * | 2007-10-25 | 2010-08-11 | General Electric Company | Fluorinated dihydrotetrabenazine ether imaging agents and probes |
| US7897770B2 (en) * | 2007-10-25 | 2011-03-01 | General Electric Company | Fluorinated dihydrotetrabenazine ether imaging agents and probes |
| US7897769B2 (en) * | 2007-10-25 | 2011-03-01 | General Electric Company | Intermediates for fluorinated dihydrotetrabenazine ether imaging agents and probes |
| US7910738B2 (en) * | 2007-11-29 | 2011-03-22 | General Electric Company | Intermediates for alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes |
| US8053578B2 (en) * | 2007-11-29 | 2011-11-08 | General Electric Company | Alpha-fluoroalkyl dihydrotetrabenazine imaging agents and probes |
| US7902364B2 (en) * | 2007-11-29 | 2011-03-08 | General Electric Company | Alpha-fluoroalkyl tetrabenazine and dihydrotetrabenazine imaging agents and probes |
| US8013161B1 (en) * | 2007-12-07 | 2011-09-06 | General Electric Company | Fluoroalkyl tetrabenazine carbinol compounds as imaging agents and probes |
| US7919622B2 (en) * | 2007-12-07 | 2011-04-05 | Kande Kankanamalage Dayarathna Amarasinghe | Intermediates for fluorinated tetrabenazine carbinol compounds imaging agents and probes |
| CN104744456A (zh) * | 2010-06-01 | 2015-07-01 | 奥斯拜客斯制药有限公司 | Vmat2的苯并喹啉酮抑制剂 |
| US9550780B2 (en) | 2012-09-18 | 2017-01-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| US9346800B2 (en) | 2012-09-18 | 2016-05-24 | Auspex Pharmaceuticals, Inc. | Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 |
| JP6542222B2 (ja) | 2013-12-03 | 2019-07-10 | オースペックス ファーマシューティカルズ インコーポレイテッド | ベンゾキノリン化合物の製造方法 |
| KR20240049625A (ko) | 2015-03-06 | 2024-04-16 | 오스펙스 파마슈티칼스, 인코포레이티드 | 비정상적 불수의 운동 장애의 치료 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3053845A (en) * | 1962-09-11 | Benzofykedocolines | ||
| CH341161A (de) * | 1956-02-08 | 1959-09-30 | Hoffmann La Roche | Verfahren zur Herstellung von substituierten 2-Hydroxy-benzo [ a ] chinolizinen |
| FI49422C (fi) * | 1961-08-29 | 1975-06-10 | Pfizer | Menetelmä terapeuttisesti arvokkaiden 2-asemassa substituoitujen bents opyridokoliinien (bentso/a/kinolitsiinien) sekä näiden happoadditiosuo lojen valmistamiseksi. |
| US3634431A (en) * | 1969-12-22 | 1972-01-11 | Miles Lab | Acylated and alkylated derivatives of 2-aminohexahydrobenzo(a)quinolizines |
| YU264675A (en) * | 1974-10-23 | 1982-05-31 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaining benzo (a)-quinolizidine derivatives |
| US4133812A (en) * | 1975-11-21 | 1979-01-09 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for producing benzo (a) quinolizine derivatives |
-
1977
- 1977-06-15 HU HU77CI1751A patent/HU175890B/hu unknown
-
1978
- 1978-01-02 NL NL7800024A patent/NL7800024A/xx not_active Application Discontinuation
- 1978-06-07 DE DE19782824905 patent/DE2824905A1/de not_active Ceased
- 1978-06-09 AT AT0419478A patent/AT363939B/de not_active IP Right Cessation
- 1978-06-13 FR FR7817628A patent/FR2394546A1/fr active Granted
- 1978-06-13 IT IT68372/78A patent/IT1203186B/it active
- 1978-06-14 SU SU782626939A patent/SU719499A3/ru active
- 1978-06-14 GB GB7826848A patent/GB2000135B/en not_active Expired
- 1978-06-14 ES ES470787A patent/ES470787A1/es not_active Expired
- 1978-06-14 FI FI781898A patent/FI65245C/fi not_active IP Right Cessation
- 1978-06-14 US US05/915,379 patent/US4193998A/en not_active Expired - Lifetime
- 1978-06-14 JP JP7100578A patent/JPS545999A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2394546A1 (fr) | 1979-01-12 |
| DE2824905A1 (de) | 1979-01-04 |
| FI65245B (fi) | 1983-12-30 |
| GB2000135B (en) | 1982-01-20 |
| NL7800024A (nl) | 1978-12-19 |
| IT1203186B (it) | 1989-02-15 |
| FR2394546B1 (it) | 1982-07-16 |
| FI65245C (fi) | 1984-04-10 |
| GB2000135A (en) | 1979-01-04 |
| US4193998A (en) | 1980-03-18 |
| SU719499A3 (ru) | 1980-02-29 |
| HU175890B (en) | 1980-11-28 |
| ES470787A1 (es) | 1979-02-01 |
| JPS545999A (en) | 1979-01-17 |
| AT363939B (de) | 1981-09-10 |
| FI781898A (fi) | 1978-12-16 |
| ATA419478A (de) | 1981-02-15 |
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