IT1314243B1 - Metodo per la preparazione di citalopram. - Google Patents
Metodo per la preparazione di citalopram.Info
- Publication number
- IT1314243B1 IT1314243B1 ITMI992505A IT1314243B1 IT 1314243 B1 IT1314243 B1 IT 1314243B1 IT MI992505 A ITMI992505 A IT MI992505A IT 1314243 B1 IT1314243 B1 IT 1314243B1
- Authority
- IT
- Italy
- Prior art keywords
- propyl magnesium
- dimethylamino
- preparation
- citalopram
- magnesium halide
- Prior art date
Links
- -1 3-(N,N-dimethylamino)propyl magnesium halide Chemical class 0.000 title abstract 4
- WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 3
- 229960001653 citalopram Drugs 0.000 title abstract 3
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 206010012289 Dementia Diseases 0.000 title 1
- 208000026106 cerebrovascular disease Diseases 0.000 title 1
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical class C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- ROSDSFDQCJNGOL-UHFFFAOYSA-N protonated dimethyl amine Natural products CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 3
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 230000001777 nootropic effect Effects 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200150056A ES2169709A1 (es) | 1999-10-25 | 1999-10-25 | Metodo para la preparacion de citalopram |
| CH01179/01A CH692421A5 (de) | 1999-10-25 | 1999-10-25 | Verfahren zur Herstellung von Citalopram. |
| PCT/DK1999/000581 WO2000012044A2 (en) | 1999-10-25 | 1999-10-25 | Method for the preparation of citalopram |
| CH02004/01A CH692298A5 (de) | 1999-10-25 | 1999-10-25 | Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI992505A0 ITMI992505A0 (it) | 1999-12-01 |
| ITMI992505A1 ITMI992505A1 (it) | 2001-06-01 |
| IT1314243B1 true IT1314243B1 (it) | 2002-12-06 |
Family
ID=27178688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT99MI002505 IT1314243B1 (it) | 1999-10-25 | 1999-12-01 | Metodo per la preparazione di citalopram. |
Country Status (2)
| Country | Link |
|---|---|
| CZ (1) | CZ292992B6 (cs) |
| IT (1) | IT1314243B1 (cs) |
-
1999
- 1999-10-25 CZ CZ20012246A patent/CZ292992B6/cs not_active IP Right Cessation
- 1999-12-01 IT IT99MI002505 patent/IT1314243B1/it active
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI992505A1 (it) | 2001-06-01 |
| CZ20012246A3 (cs) | 2001-09-12 |
| ITMI992505A0 (it) | 1999-12-01 |
| CZ292992B6 (cs) | 2004-01-14 |
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