IT1302700B1 - Procedimento per la preparazione di un derivato dell'isobenzofurano - Google Patents
Procedimento per la preparazione di un derivato dell'isobenzofuranoInfo
- Publication number
- IT1302700B1 IT1302700B1 ITMI982242A IT1302700B1 IT 1302700 B1 IT1302700 B1 IT 1302700B1 IT MI982242 A ITMI982242 A IT MI982242A IT 1302700 B1 IT1302700 B1 IT 1302700B1
- Authority
- IT
- Italy
- Prior art keywords
- new
- preparation
- citalopram
- compound
- antidepressant
- Prior art date
Links
- WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 4
- 229960001653 citalopram Drugs 0.000 title abstract 4
- -1 oxazoline compound Chemical class 0.000 title abstract 3
- 230000001430 anti-depressive effect Effects 0.000 title abstract 2
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 229940005513 antidepressants Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000003999 initiator Substances 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 150000002918 oxazolines Chemical class 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 150000003549 thiazolines Chemical class 0.000 abstract 1
- 125000002769 thiazolinyl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Priority Applications (28)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI002242 IT1302700B1 (it) | 1998-10-20 | 1998-10-20 | Procedimento per la preparazione di un derivato dell'isobenzofurano |
| JP2000577159A JP3892667B2 (ja) | 1998-10-20 | 1999-10-19 | シタロプラムの製造方法 |
| AT99950506T ATE230738T1 (de) | 1998-10-20 | 1999-10-19 | Verfahren zur herstellung von citalopram |
| PCT/DK1999/000576 WO2000023431A1 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| EA200100457A EA002977B1 (ru) | 1998-10-20 | 1999-10-19 | Способ получения циталопрама |
| NZ510858A NZ510858A (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| CN99812369A CN1129592C (zh) | 1998-10-20 | 1999-10-19 | 制备西酞普兰的方法 |
| DE69904853T DE69904853T2 (de) | 1998-10-20 | 1999-10-19 | Verfahren zur herstellung von citalopram |
| US09/830,109 US6365747B1 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| CZ20011418A CZ299920B6 (cs) | 1998-10-20 | 1999-10-19 | Zpusob výroby citalopramu |
| HU0104128A HU228576B1 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| SK535-2001A SK285719B6 (sk) | 1998-10-20 | 1999-10-19 | Spôsob prípravy citalopramu a medziprodukty |
| EP99950506A EP1123284B1 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| KR10-2001-7004889A KR100411505B1 (ko) | 1998-10-20 | 1999-10-19 | 시탈로프람의 제조방법 |
| DK99950506T DK1123284T3 (da) | 1998-10-20 | 1999-10-19 | Fremgangsmåde til fremstilling af citalopram |
| CA002291134A CA2291134C (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| IL14234699A IL142346A0 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| AU63260/99A AU746665B2 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| PL347189A PL199423B1 (pl) | 1998-10-20 | 1999-10-19 | Sposób wytwarzania citalopramu |
| SI9930214T SI1123284T1 (en) | 1998-10-20 | 1999-10-19 | Method for the preparation of citalopram |
| ES99950506T ES2189502T3 (es) | 1998-10-20 | 1999-10-19 | Metodo para la prevencion de citalopram. |
| BRPI9915158-8A BR9915158B1 (pt) | 1998-10-20 | 1999-10-19 | método para preparação de citalopram, e, compostos da fórmula geral viii, ix e iv, ou qualquer de seus enantiÈmeros e sais com adição de ácido do mesmo. |
| ARP990105305A AR018693A1 (es) | 1998-10-20 | 1999-10-20 | MÉTODO PARA LA PREPARACIoN DE CITALOPRAM Y COMPUESTOS INTERMEDIARIOS PARA USO EN DICHO MÉTODO. |
| IS5911A IS2256B (is) | 1998-10-20 | 2001-03-30 | Aðferð til framleiðslu á sítalóprami |
| ZA200102822A ZA200102822B (en) | 1998-10-20 | 2001-04-05 | Method for the preparation of citalopram. |
| NO20011936A NO327038B1 (no) | 1998-10-20 | 2001-04-19 | Fremgangsmate for fremstilling av citalopram |
| BG105457A BG64704B1 (bg) | 1998-10-20 | 2001-04-20 | Метод за получаване на циталопрам |
| HK02103712.9A HK1042297B (zh) | 1998-10-20 | 2002-05-16 | 製備西酞普蘭的方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI002242 IT1302700B1 (it) | 1998-10-20 | 1998-10-20 | Procedimento per la preparazione di un derivato dell'isobenzofurano |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI982242A0 ITMI982242A0 (it) | 1998-10-20 |
| ITMI982242A1 ITMI982242A1 (it) | 2000-04-20 |
| IT1302700B1 true IT1302700B1 (it) | 2000-09-29 |
Family
ID=11380895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT98MI002242 IT1302700B1 (it) | 1998-10-20 | 1998-10-20 | Procedimento per la preparazione di un derivato dell'isobenzofurano |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1302700B1 (it) |
| ZA (1) | ZA200102822B (it) |
-
1998
- 1998-10-20 IT IT98MI002242 patent/IT1302700B1/it active IP Right Grant
-
2001
- 2001-04-05 ZA ZA200102822A patent/ZA200102822B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI982242A1 (it) | 2000-04-20 |
| ZA200102822B (en) | 2001-10-08 |
| ITMI982242A0 (it) | 1998-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |