IT1299195B1 - Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati - Google Patents

Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati

Info

Publication number
IT1299195B1
IT1299195B1 IT98RM000425A ITRM980425A IT1299195B1 IT 1299195 B1 IT1299195 B1 IT 1299195B1 IT 98RM000425 A IT98RM000425 A IT 98RM000425A IT RM980425 A ITRM980425 A IT RM980425A IT 1299195 B1 IT1299195 B1 IT 1299195B1
Authority
IT
Italy
Prior art keywords
composition
state
prevention
treatment
neuroprotective activity
Prior art date
Application number
IT98RM000425A
Other languages
English (en)
Inventor
Per Il Credito Sporti Istituto
Original Assignee
Sigma Tau Healthscience Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Healthscience Spa filed Critical Sigma Tau Healthscience Spa
Publication of ITRM980425A0 publication Critical patent/ITRM980425A0/it
Priority to IT98RM000425A priority Critical patent/IT1299195B1/it
Priority to MA25627A priority patent/MA26651A1/fr
Priority to PL99345279A priority patent/PL194177B1/pl
Priority to AT99926750T priority patent/ATE228369T1/de
Priority to KR1020007014521A priority patent/KR20010053059A/ko
Priority to EP99926750A priority patent/EP1089744B1/en
Priority to PCT/IT1999/000175 priority patent/WO1999066914A2/en
Priority to TR2000/03736T priority patent/TR200003736T2/xx
Priority to CA2334858A priority patent/CA2334858C/en
Priority to JP2000555600A priority patent/JP2002518438A/ja
Priority to US09/719,551 priority patent/US6346282B1/en
Priority to BR9912179-4A priority patent/BR9912179A/pt
Priority to DK99926750T priority patent/DK1089744T3/da
Priority to CN99807870A priority patent/CN1307479A/zh
Priority to EEP200000729A priority patent/EE200000729A/xx
Priority to SK1930-2000A priority patent/SK19302000A3/sk
Priority to HU0102546A priority patent/HUP0102546A3/hu
Priority to IL14015999A priority patent/IL140159A0/xx
Priority to ES99926750T priority patent/ES2188178T3/es
Priority to DE69904173T priority patent/DE69904173T2/de
Priority to PT99926750T priority patent/PT1089744E/pt
Priority to NZ508882A priority patent/NZ508882A/en
Priority to AU43910/99A priority patent/AU756542B2/en
Priority to ARP990103007 priority patent/AR019703A1/es
Priority to TNTNSN99135A priority patent/TNSN99135A1/fr
Publication of ITRM980425A1 publication Critical patent/ITRM980425A1/it
Application granted granted Critical
Publication of IT1299195B1 publication Critical patent/IT1299195B1/it
Priority to IS5765A priority patent/IS5765A/is
Priority to NO20006430A priority patent/NO20006430L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
IT98RM000425A 1998-06-25 1998-06-25 Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati IT1299195B1 (it)

Priority Applications (27)

Application Number Priority Date Filing Date Title
IT98RM000425A IT1299195B1 (it) 1998-06-25 1998-06-25 Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati
MA25627A MA26651A1 (fr) 1998-06-25 1999-06-15 Composition neuroprotectrice pour la prevention et / ou le traitement des troubles nerveux ou de comportement dus aux etats d'anxiete ou de depression
EEP200000729A EE200000729A (et) 1998-06-25 1999-06-17 Neuroosivastane kompositsioon hirmuseisunditest või depressioonist tingitud neurootiliste ning käitumuslike muutuste ennetamiseks ja/või raviks
SK1930-2000A SK19302000A3 (sk) 1998-06-25 1999-06-17 NEUROPROTEKTÖVNA KOMPOZÖCIA NA PREVENCIU A/ALEBO LIE¬ENIE NERVOVíCH A BEHAVIORµLNYCH ZMIEN V DâSLEDKU STRACHU ALEBO DEPRESIE
KR1020007014521A KR20010053059A (ko) 1998-06-25 1999-06-17 불안 상태 또는 우울증으로 인한 신경 및 행동 변화의예방 및/또는 치료를 위한 신경보호 조성물
EP99926750A EP1089744B1 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression, comprising acetyl-l-carnitine and hypericin
PCT/IT1999/000175 WO1999066914A2 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression, comprising acetyl-l-carnitine and hypericin
TR2000/03736T TR200003736T2 (tr) 1998-06-25 1999-06-17 Anksiyete durumlarına ya da depresyona bağlı değişikliklerin önlenmesi
CA2334858A CA2334858C (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression
JP2000555600A JP2002518438A (ja) 1998-06-25 1999-06-17 不安状態または鬱病による神経および行動変化の予防および／または治療のための神経保護組成物
US09/719,551 US6346282B1 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression, comprising acetyl-L-carnitine and hypericin
BR9912179-4A BR9912179A (pt) 1998-06-25 1999-06-17 Composição neuroprotetora para a prevenção e/ou tratamento de alterações nervosas e do comportamento devido a estados de ansiedade ou depressão
DK99926750T DK1089744T3 (da) 1998-06-25 1999-06-17 Neurobeskyttende præparat til forebyggelse og/eller behandling af nervøse og adfærdsmæssige ændringer på grund af angsttilstande eller depression omfattende acetyl-L-carnitin og hypericin
CN99807870A CN1307479A (zh) 1998-06-25 1999-06-17 用于预防和/或治疗因焦虑状态或抑郁所致神经和行为病变的神经保护组合物
PL99345279A PL194177B1 (pl) 1998-06-25 1999-06-17 Kompozycja zawierająca acetylo-L-karnitynę i jej zastosowania
AT99926750T ATE228369T1 (de) 1998-06-25 1999-06-17 Nervenschützende zusammensetzung zur prophylaxe und behandlung von nervös- und verhaltungsänderungen durch angstartigen zuständen oder depressionen, die acetyl-l- carnitin und hypericin enthalt
HU0102546A HUP0102546A3 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression
IL14015999A IL140159A0 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioral alterations due to anxiety states or depression
ES99926750T ES2188178T3 (es) 1998-06-25 1999-06-17 Composicion neuroprotectora para la prevencion y/o tratamiento de alteraciones nerviosas y del comportamiento debido a estados de ansiedad o depresion, que comprende acetil-l-carnitina e hpericina.
DE69904173T DE69904173T2 (de) 1998-06-25 1999-06-17 Nervenschützende zusammensetzung zur prophylaxe und behandlung von nervös- und verhaltungsänderungen durch angstartigen zuständen oder depressionen, die acetyl-l-carnitin und hypericin enthalt
PT99926750T PT1089744E (pt) 1998-06-25 1999-06-17 Composicao neuroprotectora para a prevencao e/ou tratamento de perturbacoes nervosas e de comportamento devidas a estados de ansiedade ou de depressao
NZ508882A NZ508882A (en) 1998-06-25 1999-06-17 Carnitines and hypericin displaying synergism in compositions for treating anxiety and depression
AU43910/99A AU756542B2 (en) 1998-06-25 1999-06-17 Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression
ARP990103007 AR019703A1 (es) 1998-06-25 1999-06-23 Composicion neuroprotectora para la prevencion y/o tratamiento de alteraciones nerviosas y del comportamiento debidas a estados de ansiedad o depresion
TNTNSN99135A TNSN99135A1 (fr) 1998-06-25 1999-06-25 Composition neuroprotectrice pour la prevention et/ou le traitement des troubles nerveux ou de comportement dus aux etats d'anxiete ou de depression
IS5765A IS5765A (is) 1998-06-25 2000-12-08 Taugavarnarsamsetning til að fyrirbyggja og/eða meðhöndla tauga- og atferlisbreytingar vegna kvíða ástands og þunglyndis
NO20006430A NO20006430L (no) 1998-06-25 2000-12-15 Neurobeskyttende sammensetning for forhindring og/eller behandling av nerve- og atferdsforandringer på grunn av angsttilstander eller depresjoner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98RM000425A IT1299195B1 (it) 1998-06-25 1998-06-25 Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati

Publications (3)

Publication Number Publication Date
ITRM980425A0 ITRM980425A0 (it) 1998-06-25
ITRM980425A1 ITRM980425A1 (it) 1999-12-25
IT1299195B1 true IT1299195B1 (it) 2000-02-29

Family

ID=11406010

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98RM000425A IT1299195B1 (it) 1998-06-25 1998-06-25 Composizione ad attivita' neuroprotettiva per la prevenzione ed il trattamento delle alterazioni nervose e comportamentali legate a stati

Country Status (26)

Country Link
US (1) US6346282B1 (it)
EP (1) EP1089744B1 (it)
JP (1) JP2002518438A (it)
KR (1) KR20010053059A (it)
CN (1) CN1307479A (it)
AT (1) ATE228369T1 (it)
AU (1) AU756542B2 (it)
BR (1) BR9912179A (it)
CA (1) CA2334858C (it)
DE (1) DE69904173T2 (it)
DK (1) DK1089744T3 (it)
EE (1) EE200000729A (it)
ES (1) ES2188178T3 (it)
HU (1) HUP0102546A3 (it)
IL (1) IL140159A0 (it)
IS (1) IS5765A (it)
IT (1) IT1299195B1 (it)
MA (1) MA26651A1 (it)
NO (1) NO20006430L (it)
NZ (1) NZ508882A (it)
PL (1) PL194177B1 (it)
PT (1) PT1089744E (it)
SK (1) SK19302000A3 (it)
TN (1) TNSN99135A1 (it)
TR (1) TR200003736T2 (it)
WO (1) WO1999066914A2 (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6348495B1 (en) * 1996-06-06 2002-02-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Method for treating celiac disease
DE10015617A1 (de) * 2000-03-29 2001-10-04 Peter Laetzsch Migränemittel
US7208180B2 (en) * 2000-05-08 2007-04-24 N.V. Nutricia Method and preparation for the preventing and/or treating vascular disorders and secondary disorders associated therewith
US7226916B1 (en) 2000-05-08 2007-06-05 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
IT1317035B1 (it) * 2000-05-30 2003-05-26 Sigma Tau Healthscience Spa Integratore ad attivita' antiossidante comprendente unaalcanoilcarnitina ed una associazione di polifenoli estratti dal
US7700074B2 (en) 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US7407778B2 (en) * 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
DE10213571A1 (de) * 2002-03-26 2003-10-23 Lichtwer Pharma Ag Pflanzenextrakte und deren Anwendung
US7674482B2 (en) * 2002-08-27 2010-03-09 Targeted Medical Pharma Inc. Method and compositions for potentiating pharmaceuticals with amino acid based medical foods
US20040067986A1 (en) * 2002-10-04 2004-04-08 Nathan Sassover Neuro-degenerative inhibitor, neuro-endocrine modulator, and neuro-cerebral metabolism enhancer
DE602004022301D1 (de) * 2003-05-29 2009-09-10 Jay W Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
US20070065486A1 (en) * 2004-05-21 2007-03-22 Migco Limited Migraine remedy
US20060115555A1 (en) * 2004-12-01 2006-06-01 Foulger Sidney W Nutritional supplements containing xanthone extracts
US20060115556A1 (en) * 2004-12-01 2006-06-01 Foulger Sidney W Nutritional supplement drink containing xanthone extracts
EP1854486A3 (de) * 2006-03-14 2010-06-02 Wilfried P. Bieger Verwendung von Neurotransmitter-Derivaten zur Herstellung von Mitteln zur Behandlung von neuroendokrinen gesundheitlichen Störungen
US8461389B2 (en) 2008-04-18 2013-06-11 University College Dublin, National University Of Ireland, Dublin Psycho-pharmaceuticals
BRPI0921679A2 (pt) * 2008-11-11 2016-02-16 Sigma Tau Ind Farmaceuti composto útil para tratar celulite
BRPI0900614A2 (pt) 2009-02-13 2011-06-28 Univ Fed Do Rio Grande Do Sul Ufrgs extrato vegetal neuroativo, composição farmacêutica compreendendo o mesmo e processo para sua produção
JP2013530170A (ja) * 2010-06-16 2013-07-25 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 神経組織における神経発生を増大させるための方法における使用のためのアセチル−カルニチン
EP2600862B1 (en) 2010-08-05 2016-04-20 Case Western Reserve University Inhibitors of erk for developmental disorders of neuronal connectivity
JP2014145857A (ja) 2013-01-28 2014-08-14 Sony Corp 表示装置およびその製造方法、並びに電子機器
WO2016126169A1 (ru) * 2015-02-04 2016-08-11 Общество С Ограниченной Ответственностью "Консорциум-Пик" Способ повышения эффективности терапии антидепрессантом в комплексной антидепрессивной терапии и фармацевтическая комбинация

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism
DE4239959A1 (de) * 1992-11-27 1994-06-01 Schwabe Willmar Gmbh & Co Johanniskraut-Trockenextrakt, Verfahren zu seiner Herstellung und seine Verwendung
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
US5911992A (en) * 1997-06-12 1999-06-15 A. Glenn Braswell Method for controlling weight with hypericum perforatum and garcinia cambogia

Also Published As

Publication number Publication date
SK19302000A3 (sk) 2001-09-11
ITRM980425A0 (it) 1998-06-25
DE69904173T2 (de) 2003-08-28
TR200003736T2 (tr) 2001-06-21
US6346282B1 (en) 2002-02-12
TNSN99135A1 (fr) 2005-11-10
PL194177B1 (pl) 2007-05-31
BR9912179A (pt) 2001-04-10
IS5765A (is) 2000-12-08
PT1089744E (pt) 2003-04-30
JP2002518438A (ja) 2002-06-25
HUP0102546A2 (hu) 2001-10-28
EP1089744A2 (en) 2001-04-11
AU4391099A (en) 2000-01-10
HUP0102546A3 (en) 2003-08-28
CA2334858C (en) 2010-08-24
NO20006430D0 (no) 2000-12-15
DK1089744T3 (da) 2003-03-24
WO1999066914A2 (en) 1999-12-29
ITRM980425A1 (it) 1999-12-25
EP1089744B1 (en) 2002-11-27
ATE228369T1 (de) 2002-12-15
KR20010053059A (ko) 2001-06-25
CA2334858A1 (en) 1999-12-29
NO20006430L (no) 2001-02-21
NZ508882A (en) 2002-06-28
PL345279A1 (en) 2001-12-03
WO1999066914A3 (en) 2000-04-06
MA26651A1 (fr) 2004-12-20
EE200000729A (et) 2002-06-17
ES2188178T3 (es) 2003-06-16
CN1307479A (zh) 2001-08-08
AU756542B2 (en) 2003-01-16
IL140159A0 (en) 2002-02-10
DE69904173D1 (de) 2003-01-09

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