DE69519577T2 - Prednisolonmetasulfobenzoat-zusammensetzung zur behandlung von entzündungserkrankung des darmes - Google Patents

Prednisolonmetasulfobenzoat-zusammensetzung zur behandlung von entzündungserkrankung des darmes

Info

Publication number
DE69519577T2
DE69519577T2 DE69519577T DE69519577T DE69519577T2 DE 69519577 T2 DE69519577 T2 DE 69519577T2 DE 69519577 T DE69519577 T DE 69519577T DE 69519577 T DE69519577 T DE 69519577T DE 69519577 T2 DE69519577 T2 DE 69519577T2
Authority
DE
Germany
Prior art keywords
prednisolon
sulfobenzoate
colon
composition
metal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69519577T
Other languages
English (en)
Other versions
DE69519577D1 (de
Inventor
Christopher James Speirs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENTEROTECH Ltd
Original Assignee
ENTEROTECH Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ENTEROTECH Ltd filed Critical ENTEROTECH Ltd
Application granted granted Critical
Publication of DE69519577D1 publication Critical patent/DE69519577D1/de
Publication of DE69519577T2 publication Critical patent/DE69519577T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69519577T 1994-08-12 1995-08-11 Prednisolonmetasulfobenzoat-zusammensetzung zur behandlung von entzündungserkrankung des darmes Expired - Lifetime DE69519577T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9416310A GB2292079B (en) 1994-08-12 1994-08-12 Coated prednisolone preparation for the treatment of inflamatory bowel disease
PCT/GB1995/001900 WO1996004918A1 (en) 1994-08-12 1995-08-11 Prednisolone metasulphobenzoate preparation for the treatment of inflammatory bowel disease

Publications (2)

Publication Number Publication Date
DE69519577D1 DE69519577D1 (de) 2001-01-11
DE69519577T2 true DE69519577T2 (de) 2001-08-09

Family

ID=10759780

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519577T Expired - Lifetime DE69519577T2 (de) 1994-08-12 1995-08-11 Prednisolonmetasulfobenzoat-zusammensetzung zur behandlung von entzündungserkrankung des darmes

Country Status (7)

Country Link
US (1) US5834021A (de)
EP (1) EP0772443B1 (de)
CA (1) CA2229283C (de)
DE (1) DE69519577T2 (de)
DK (1) DK0772443T3 (de)
GB (1) GB2292079B (de)
WO (1) WO1996004918A1 (de)

Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
US20040018236A1 (en) * 1995-05-08 2004-01-29 Robert Gurny Nanoparticles for oral administration of pharmaceutical agents of low solubility
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
ES2326500T3 (es) * 1997-11-13 2009-10-13 Mowycal Lending, Llc Pequeños peptidos y metodos para el tratamiento del asma y la inflamacion.
DE19855203A1 (de) * 1998-11-30 2000-05-31 Kurt Heinz Bauer Coprozessiertes Polysaccharidprodukt
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US20010046496A1 (en) * 2000-04-14 2001-11-29 Brettman Lee R. Method of administering an antibody
IT1318625B1 (it) 2000-07-14 2003-08-27 Roberto Valducci Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
NZ532310A (en) 2001-10-05 2007-02-23 Combinatorx Inc Combinations comprising a tetra-substituted pyrimidopyrimidine and a corticosteroid for the treatment of immunoinflammatory disorders
EP1519717B1 (de) * 2002-07-05 2010-09-29 Temrel Limited Zusammensetzung zur kontrollierten wirkstoffabgabe
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
GB0329851D0 (en) * 2003-12-23 2004-01-28 Temrel Inc Process for producing particles for pharmaceutical compositions
JP2007515464A (ja) * 2003-12-23 2007-06-14 テムレル・リミテッド 医薬組成物用ペレットの製造方法
US20080089892A1 (en) 2004-01-12 2008-04-17 Eli Lilly And Co. Fc Region Variants
US20070122404A1 (en) * 2005-11-17 2007-05-31 O'keefe Theresa L Humanized immunoglobulin reactive with alpha4beta7 integrin
US20090162434A1 (en) * 2007-12-21 2009-06-25 Disphar International Bv Mesalazine tablet
WO2010042933A2 (en) 2008-10-10 2010-04-15 Northwestern University Inhibition and treatment of prostate cancer metastasis
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
MX367097B (es) 2011-05-02 2019-08-05 Millennium Pharm Inc FORMULACION PARA ANTICUERPO ANTI-A4ß7.
GB201202433D0 (en) 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release
EP3215149A4 (de) 2014-11-06 2018-06-27 Northwestern University Hemmung der motilität von krebszellen

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1228029C2 (de) * 1964-05-09 1973-05-17 Merck Ag E Verfahren zur Herstellung von Tabletten durch Pressen von Pulvergemischen ohne vorhergehende Granulation
FR5083M (de) * 1965-12-08 1967-05-16
FR8106M (de) * 1968-11-26 1970-07-27
US4115563A (en) * 1977-03-14 1978-09-19 Sterling Drug Inc. Pharmaceutical steroid formulation
US4285987A (en) * 1978-10-23 1981-08-25 Alza Corporation Process for manufacturing device with dispersion zone
KR880701098A (ko) * 1986-04-01 1988-07-25 로버어트 에이 아미테이지 메틸프레드니솔론/소디움 카르복시메틸 전분 정제 조성물
US5004613A (en) * 1987-07-27 1991-04-02 Mcneil-Ppc, Inc. Oral sustained release pharmaceutical formulation and process
US5049394A (en) * 1987-09-11 1991-09-17 E. R. Squibb & Sons, Inc. Pharmaceutical composition containing high drug load and method for preparing same
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5178866A (en) * 1990-03-23 1993-01-12 Alza Corporation Dosage form for delivering drug to the intestine
EP0533799B1 (de) * 1990-06-20 1995-10-18 Advanced Polymer Systems, Inc. Zusammensetzungen und verfahren für die kontrollierte freisetzung von löslichen wirkstoffen
GB2253346A (en) * 1991-02-22 1992-09-09 John Rhodes Delayed release oral dosage forms for treatment of intestinal disorders

Also Published As

Publication number Publication date
EP0772443B1 (de) 2000-12-06
DK0772443T3 (da) 2001-02-19
WO1996004918A1 (en) 1996-02-22
GB2292079B (en) 1998-07-15
DE69519577D1 (de) 2001-01-11
US5834021A (en) 1998-11-10
EP0772443A1 (de) 1997-05-14
GB9416310D0 (en) 1994-10-05
CA2229283C (en) 2005-11-08
GB2292079A (en) 1996-02-14
CA2229283A1 (en) 1996-02-22

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Legal Events

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