IT1276171B1 - Derivati chinolinici - Google Patents
Derivati chinoliniciInfo
- Publication number
- IT1276171B1 IT1276171B1 ITMI952462A IT1276171B1 IT 1276171 B1 IT1276171 B1 IT 1276171B1 IT MI952462 A ITMI952462 A IT MI952462A IT 1276171 B1 IT1276171 B1 IT 1276171B1
- Authority
- IT
- Italy
- Prior art keywords
- neurokinin
- treating
- useful
- carboxamide derivatives
- receptor antagonists
- Prior art date
Links
- LEWDKQKVAFOMPI-UHFFFAOYSA-N quinoline-4-carboxamide Chemical class C1=CC=C2C(C(=O)N)=CC=NC2=C1 LEWDKQKVAFOMPI-UHFFFAOYSA-N 0.000 title abstract 2
- 101000831616 Homo sapiens Protachykinin-1 Proteins 0.000 title 1
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 102000002003 Neurokinin-3 Receptors Human genes 0.000 title 1
- 108010040716 Neurokinin-3 Receptors Proteins 0.000 title 1
- 102100024304 Protachykinin-1 Human genes 0.000 title 1
- 230000007815 allergy Effects 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 208000023504 respiratory system disease Diseases 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004656 alkyl sulfonylamino group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (29)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002462 IT1276171B1 (it) | 1995-11-24 | 1995-11-24 | Derivati chinolinici |
| ARP960105282A AR004735A1 (es) | 1995-11-24 | 1996-11-21 | Quinoleina 4-amido sustituida, un procedimiento para su preparacion, una composicion farmaceutica que los contiene y el uso de los mismos para lapreparacion de un medicamento. |
| JP09520158A JP2000513325A (ja) | 1995-11-24 | 1996-11-22 | キノリン―４―カルボキシアミド誘導体、その製法およびそのニューロキニン３（ｎｋ―３）およびニューロキニン２（ｎｋ―２）レセプター・アンタゴニストとしての使用 |
| APAP/P/1998/001238A AP9801238A0 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (NK-3)- and neurokinin 2 (NK-2) receptor antagonists. |
| PL96326928A PL326928A1 (en) | 1995-11-24 | 1996-11-22 | Quinolin-4-carboxyamidic derivatives, their production and their application as antagonists ofneurokinin-3 (nk-3) and neurokinin-2 (nk-2) |
| TR1998/00883T TR199800883T2 (xx) | 1995-11-24 | 1996-11-22 | Kuinolin-4-Karboksamid t�revleri, haz�rlanmalar� ve n�rokinin 3 (NK-3)- ve n�rokinin 2 (NK-2) resept�r antagonistleri olarak kullan�mlar�. |
| EP96941025A EP1019377A1 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (nk-3)- and neurokinin 2 (nk-2) receptor antagonists. |
| IL12441896A IL124418A0 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives their preparation and their use as neurokinin 3 (NK-3)- and neurokinin 2 (NK-2) receptor antagonists |
| KR1019980703874A KR19990071598A (ko) | 1995-11-24 | 1996-11-22 | 퀴놀린-4-카르복사미드 유도체, 그의 제조 방법 및 뉴로키닌3 (nk-3) 및 뉴로키닌 2 (nk-2) 수용체 길항제로서의 그 용도 |
| EA199800538A EA001771B1 (ru) | 1995-11-24 | 1996-11-22 | Производные хинолин-4-карбоксамида, их получение и их применение в качестве антагонистов рецептора нейрокинина-3 (-к-3) и нейрокинина-2 (-к-2) |
| HU9901016A HUP9901016A3 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3(nk-3)-and neurokinin 2(nk-2) receptor antagonists |
| SK668-98A SK66898A3 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use |
| AU10318/97A AU1031897A (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (nk-3)- and neurokinin 2 (nk-2) receptor antagonists. |
| MA24399A MA24011A1 (fr) | 1995-11-24 | 1996-11-22 | Procede pour la preparation de nouveaux composes |
| UY24375A UY24375A1 (es) | 1995-11-24 | 1996-11-22 | Procedimiento para la preparacion de derivados de quinolin-4 -carboxamida |
| CZ981580A CZ158098A3 (cs) | 1995-11-24 | 1996-11-22 | Chinolin-4-karboxamidové deriváty, způsob jejich přípravy, farmaceutický prostředek a použití jako antagonistů receptorů neurokininu 3(NK-3) a 2(NK-2) |
| ZA9609811A ZA969811B (en) | 1995-11-24 | 1996-11-22 | Novel quinoline derivatives. |
| PCT/EP1996/005207 WO1997019926A1 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (nk-3)- and neurokinin 2 (nk-2) receptor antagonists. |
| CN96199747A CN1207729A (zh) | 1995-11-24 | 1996-11-22 | 喹啉－4－酰胺衍生物,它们的制备以及它们作为神经激肽3(nk－3)和神经激肽2(nk－2)受体拮抗剂的应用 |
| CA002238328A CA2238328A1 (en) | 1995-11-24 | 1996-11-22 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 (nk-3)- and neurokinin 2 (nk-2) receptor antagonists. |
| BR9611757A BR9611757A (pt) | 1995-11-24 | 1996-11-22 | Derivados quinolino-4-carboxamida sua preparação e seu uso como antagonitas de receptor neuroquinina 3 (nk-3)-e neuroquinina 2 (nk-2) |
| DZ960173A DZ2128A1 (fr) | 1995-11-24 | 1996-11-23 | Composés nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
| TW085114501A TW409123B (en) | 1995-11-24 | 1996-11-23 | Quinoline derivatives and pharmaceutical composition containing the same |
| UY24555A UY24555A1 (es) | 1995-11-24 | 1997-05-16 | Nuevos compuestos |
| OA9800062A OA11011A (en) | 1995-11-24 | 1998-05-22 | Quinoline-4-carboxamide derivatives their preparation and their use as neurokin 3 (nk-3)-and neurokin 2 (nk-2)receptor antagonists |
| NO19982333A NO311213B1 (no) | 1995-11-24 | 1998-05-22 | Kinolinkarboksamid-derivater, deres fremstilling og deres anvendelse som Neurokinin 3 (NK-3)- og Neurokinin 2 (NK-2)reseptorantagonister, samt farmasöytiske preparater inneholdendedem |
| MX9804108A MX9804108A (es) | 1995-11-24 | 1998-05-22 | Derivados de quinolina-4-carboxamida, su preparacion y uso como antagonistas receptores de neuroquinina 3 (nk-3)- y neuroquinina 2 (kn-2). |
| BG102557A BG102557A (bg) | 1995-11-24 | 1998-06-18 | Производни на хинолин-4-карбоксамиди, метод за получаването им и използването им като антагонисти на неврокинин 3 / nк-/ и неврокинин 2 / nк-/ рецепторите |
| US09/994,402 US20020068827A1 (en) | 1995-11-24 | 2001-11-26 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 ( NK-3 ) - and neurokinin 2 ( NK-3 ) receptor antagonists |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI002462 IT1276171B1 (it) | 1995-11-24 | 1995-11-24 | Derivati chinolinici |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI952462A0 ITMI952462A0 (it) | 1995-11-24 |
| ITMI952462A1 ITMI952462A1 (it) | 1997-05-24 |
| IT1276171B1 true IT1276171B1 (it) | 1997-10-27 |
Family
ID=11372597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95MI002462 IT1276171B1 (it) | 1995-11-24 | 1995-11-24 | Derivati chinolinici |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1276171B1 (it) |
| ZA (1) | ZA969811B (it) |
-
1995
- 1995-11-24 IT IT95MI002462 patent/IT1276171B1/it active IP Right Grant
-
1996
- 1996-11-22 ZA ZA9609811A patent/ZA969811B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA969811B (en) | 1998-05-22 |
| ITMI952462A0 (it) | 1995-11-24 |
| ITMI952462A1 (it) | 1997-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |