IT1264812B1 - Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi - Google Patents

Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi

Info

Publication number
IT1264812B1
IT1264812B1 IT93MI001678A ITMI931678A IT1264812B1 IT 1264812 B1 IT1264812 B1 IT 1264812B1 IT 93MI001678 A IT93MI001678 A IT 93MI001678A IT MI931678 A ITMI931678 A IT MI931678A IT 1264812 B1 IT1264812 B1 IT 1264812B1
Authority
IT
Italy
Prior art keywords
formula
therapeutically active
benzothiazinonic
benzossazinonic
derivatives
Prior art date
Application number
IT93MI001678A
Other languages
English (en)
Italian (it)
Inventor
Silvio Levi
Francesca Benedini
Giorgio Bertolini
Gianni Gromo
Jacques Mizrhai
Alberto Sala
Original Assignee
Italfarmaco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco Spa filed Critical Italfarmaco Spa
Publication of ITMI931678A0 publication Critical patent/ITMI931678A0/it
Priority to IT93MI001678A priority Critical patent/IT1264812B1/it
Priority to PCT/EP1994/002354 priority patent/WO1995004048A1/en
Priority to FI960342A priority patent/FI960342A7/fi
Priority to HU9600165A priority patent/HUT74587A/hu
Priority to JP7505529A priority patent/JPH09500878A/ja
Priority to AU74945/94A priority patent/AU7494594A/en
Priority to CN94192889A priority patent/CN1128025A/zh
Priority to EP94924778A priority patent/EP0711286A1/en
Priority to CA002168099A priority patent/CA2168099A1/en
Priority to IL11047394A priority patent/IL110473A0/xx
Priority to ZA945555A priority patent/ZA945555B/xx
Priority to TW083106854A priority patent/TW277061B/zh
Publication of ITMI931678A1 publication Critical patent/ITMI931678A1/it
Priority to NO960308A priority patent/NO960308L/no
Application granted granted Critical
Publication of IT1264812B1 publication Critical patent/IT1264812B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT93MI001678A 1993-07-28 1993-07-28 Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi IT1264812B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT93MI001678A IT1264812B1 (it) 1993-07-28 1993-07-28 Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi
CN94192889A CN1128025A (zh) 1993-07-28 1994-07-18 具有治疗活性的苯并噁嗪酮和苯并噻嗪酮
CA002168099A CA2168099A1 (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones endowed with therapeutic activity
HU9600165A HUT74587A (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones and pharmaceutical compositions containing them
JP7505529A JPH09500878A (ja) 1993-07-28 1994-07-18 治療活性を有するベンゾキサジノン及びベンゾチアジノン
AU74945/94A AU7494594A (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones endowed with therapeutic activity
PCT/EP1994/002354 WO1995004048A1 (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones endowed with therapeutic activity
EP94924778A EP0711286A1 (en) 1993-07-28 1994-07-18 Benzoxazinones and benzothiazinones endowed with therapeutic activity
FI960342A FI960342A7 (fi) 1993-07-28 1994-07-18 Bentsoksatsinonit ja bentsotiatsinonit, joilla on terapeuttista aktiiv isuutta
IL11047394A IL110473A0 (en) 1993-07-28 1994-07-27 Benzoxazinones and benzothiazinones endowed with therapeutic activity
ZA945555A ZA945555B (en) 1993-07-28 1994-07-27 Benzoxazinones and benzothiazinones with therapeutic activity
TW083106854A TW277061B (cs) 1993-07-28 1994-07-27
NO960308A NO960308L (no) 1993-07-28 1996-01-25 Terapeutisk aktive benzoksaziner og benzotioanoner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001678A IT1264812B1 (it) 1993-07-28 1993-07-28 Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi

Publications (3)

Publication Number Publication Date
ITMI931678A0 ITMI931678A0 (it) 1993-07-28
ITMI931678A1 ITMI931678A1 (it) 1995-01-28
IT1264812B1 true IT1264812B1 (it) 1996-10-10

Family

ID=11366700

Family Applications (1)

Application Number Title Priority Date Filing Date
IT93MI001678A IT1264812B1 (it) 1993-07-28 1993-07-28 Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi

Country Status (13)

Country Link
EP (1) EP0711286A1 (cs)
JP (1) JPH09500878A (cs)
CN (1) CN1128025A (cs)
AU (1) AU7494594A (cs)
CA (1) CA2168099A1 (cs)
FI (1) FI960342A7 (cs)
HU (1) HUT74587A (cs)
IL (1) IL110473A0 (cs)
IT (1) IT1264812B1 (cs)
NO (1) NO960308L (cs)
TW (1) TW277061B (cs)
WO (1) WO1995004048A1 (cs)
ZA (1) ZA945555B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
CN102367239B (zh) * 2011-07-20 2015-10-28 沈阳药科大学 2-芳基-2,3-二氢-4h-1,3-苯并噻嗪-4-酮衍生物及其用途
EP2887939B1 (en) * 2012-08-27 2018-04-11 University of Tennessee Research Foundation Lpa2 receptor-specific benzoic acid derivatives
ITMI20122221A1 (it) * 2012-12-21 2014-06-22 C4T S C A R L Nuovi composti del 2,3-diidro-4h-1,3-benzossazin-4-one, metodo per prepararli e forma farmaceutica che li comprende
ES2691541T3 (es) * 2013-12-19 2018-11-27 Gilead Sciences, Inc. Compuestos heterocíclicos condensados como moduladores de canales iónicos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2443M (fr) * 1962-10-30 1964-04-06 Selvi & C Lab Bioterapico Thio-dérivés de benzo-oxazine ayant des propriétés antiphlogistiques, antipyrétiques et analgésiques.
US3459748A (en) * 1967-04-28 1969-08-05 Squibb & Sons Inc Hydroxyalkylene-substituted benzoxazines and benzothiazines
IT1136575B (it) * 1981-04-15 1986-09-03 Coli Farma Lab Esteri del 2-(2-ossietil)-2,3-diidro-h4-1,3-benzossazin-4-one ad attivita' analgesica e procedimento per la loro preparazione
IT1244472B (it) * 1990-12-14 1994-07-15 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare
FR2680172B1 (fr) * 1991-08-05 1993-11-19 Fabre Medicament Pierre Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
IT1254884B (it) * 1992-04-16 1995-10-11 Italfarmaco Spa Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare

Also Published As

Publication number Publication date
AU7494594A (en) 1995-02-28
ZA945555B (en) 1995-03-03
EP0711286A1 (en) 1996-05-15
FI960342A0 (fi) 1996-01-25
CA2168099A1 (en) 1995-02-09
NO960308D0 (no) 1996-01-25
IL110473A0 (en) 1994-10-21
FI960342L (fi) 1996-01-25
HUT74587A (en) 1997-01-28
ITMI931678A1 (it) 1995-01-28
NO960308L (no) 1996-03-13
ITMI931678A0 (it) 1993-07-28
JPH09500878A (ja) 1997-01-28
WO1995004048A1 (en) 1995-02-09
CN1128025A (zh) 1996-07-31
FI960342A7 (fi) 1996-01-25
HU9600165D0 (en) 1996-03-28
TW277061B (cs) 1996-06-01

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970729