ATE117302T1 - 2-(2-vinylpyrrolidinylthio)carbapenem-derivate. - Google Patents

2-(2-vinylpyrrolidinylthio)carbapenem-derivate.

Info

Publication number
ATE117302T1
ATE117302T1 AT90114980T AT90114980T ATE117302T1 AT E117302 T1 ATE117302 T1 AT E117302T1 AT 90114980 T AT90114980 T AT 90114980T AT 90114980 T AT90114980 T AT 90114980T AT E117302 T1 ATE117302 T1 AT E117302T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
vinylpyrrolidinylthio
lower alkyl
carbapenem derivatives
Prior art date
Application number
AT90114980T
Other languages
English (en)
Inventor
Susumu Banyu Pharmace Nakagawa
-Chome Kamimutsuna
Fumio Banyu Pharmaceuti Nakano
Norikazu Banyu Pharmaceu Otake
Ryosuke Banyu Pharmac Ushijima
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Application granted granted Critical
Publication of ATE117302T1 publication Critical patent/ATE117302T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT90114980T 1989-08-04 1990-08-03 2-(2-vinylpyrrolidinylthio)carbapenem-derivate. ATE117302T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20256889 1989-08-04

Publications (1)

Publication Number Publication Date
ATE117302T1 true ATE117302T1 (de) 1995-02-15

Family

ID=16459655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90114980T ATE117302T1 (de) 1989-08-04 1990-08-03 2-(2-vinylpyrrolidinylthio)carbapenem-derivate.

Country Status (8)

Country Link
US (1) US5095013A (de)
EP (1) EP0411664B1 (de)
JP (1) JP2707811B2 (de)
KR (1) KR910004622A (de)
AT (1) ATE117302T1 (de)
AU (1) AU631671B2 (de)
CA (1) CA2022681C (de)
DE (1) DE69016121D1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3048196B2 (ja) * 1991-06-20 2000-06-05 第一製薬株式会社 カルバペネム誘導体
AU646577B2 (en) * 1991-07-09 1994-02-24 Banyu Pharmaceutical Co., Ltd. 2-(2-substituted pyrrolidinylthio)carbapenem derivatives
KR950014111A (ko) * 1993-11-23 1995-06-15 유충식 새로운 카바페넴 유도체 및 그 제조방법
JP3983662B2 (ja) 2000-07-19 2007-09-26 エフ．ホフマン−ラ ロシュ アーゲー ピリミジン誘導体
WO2011080736A1 (en) 2009-12-29 2011-07-07 Mapi Pharma Hk Limited Intermediate compounds and processes for the preparation of tapentadol and related compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0182213B1 (de) * 1984-11-08 1990-09-26 Sumitomo Pharmaceuticals Company, Limited Carbapenemverbindungen und deren Herstellung
EP0243686B1 (de) * 1986-03-27 1992-07-15 Sumitomo Pharmaceuticals Company, Limited Beta-Lactam-Verbindungen und deren Herstellung
EP0272455B1 (de) * 1986-11-24 1993-02-10 Fujisawa Pharmaceutical Co., Ltd. 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäure-Derivate
US4925838A (en) * 1988-03-18 1990-05-15 Fujisawa Pharmaceutical Company, Ltd. 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds
CA2036941A1 (en) * 1990-02-23 1991-08-24 Isao Kawamoto Carbapenem derivatives having antibiotic activity, their preparation and their use
TW198034B (de) * 1990-03-27 1993-01-11 Manyu Seiyaku Kk

Also Published As

Publication number Publication date
DE69016121D1 (de) 1995-03-02
EP0411664B1 (de) 1995-01-18
US5095013A (en) 1992-03-10
AU631671B2 (en) 1992-12-03
EP0411664A3 (en) 1991-07-24
AU6012290A (en) 1991-02-07
KR910004622A (ko) 1991-03-29
CA2022681C (en) 1996-06-18
CA2022681A1 (en) 1991-02-05
EP0411664A2 (de) 1991-02-06
JPH04154782A (ja) 1992-05-27
JP2707811B2 (ja) 1998-02-04

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties