IT1249211B - Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo - Google Patents
Processo per la preparazione di triazolil isopropanoli in particolare fluconazoloInfo
- Publication number
- IT1249211B IT1249211B IT02058690A IT2058690A IT1249211B IT 1249211 B IT1249211 B IT 1249211B IT 02058690 A IT02058690 A IT 02058690A IT 2058690 A IT2058690 A IT 2058690A IT 1249211 B IT1249211 B IT 1249211B
- Authority
- IT
- Italy
- Prior art keywords
- isopropanols
- triazolyl
- preparation
- fluconazole
- particular fluconazole
- Prior art date
Links
- RFHAOTPXVQNOHP-UHFFFAOYSA-N fluconazole Chemical compound C1=NC=NN1CC(C=1C(=CC(F)=CC=1)F)(O)CN1C=NC=N1 RFHAOTPXVQNOHP-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004884 fluconazole Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 triazolyl isopropanols Chemical class 0.000 title 1
- FMCUPJKTGNBGEC-UHFFFAOYSA-N 1,2,4-triazol-4-amine Chemical compound NN1C=NN=C1 FMCUPJKTGNBGEC-UHFFFAOYSA-N 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000009615 deamination Effects 0.000 abstract 1
- 238000006481 deamination reaction Methods 0.000 abstract 1
- 150000003944 halohydrins Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02058690A IT1249211B (it) | 1990-06-08 | 1990-06-08 | Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo |
ES9002961A ES2026416A6 (es) | 1990-06-08 | 1990-11-21 | Procedimiento para la preparacion de triazolil-isopropanol. |
AT113291A AT400145B (de) | 1990-06-08 | 1991-06-05 | Verfahren zur herstellung von triazolyl-isopropanolen |
YU101291A YU48331B (sh) | 1990-06-08 | 1991-06-06 | Postupak za dobijanje triazolil-izopropanola |
CA 2051281 CA2051281C (en) | 1990-06-08 | 1991-09-13 | Process for the preparation of triazolyl isopropanols |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02058690A IT1249211B (it) | 1990-06-08 | 1990-06-08 | Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9020586A0 IT9020586A0 (OSRAM) | 1990-06-07 |
IT9020586A1 IT9020586A1 (it) | 1991-12-08 |
IT1249211B true IT1249211B (it) | 1995-02-20 |
Family
ID=11169192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02058690A IT1249211B (it) | 1990-06-08 | 1990-06-08 | Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo |
Country Status (5)
Country | Link |
---|---|
AT (1) | AT400145B (OSRAM) |
CA (1) | CA2051281C (OSRAM) |
ES (1) | ES2026416A6 (OSRAM) |
IT (1) | IT1249211B (OSRAM) |
YU (1) | YU48331B (OSRAM) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2049663B1 (es) * | 1992-10-13 | 1994-12-16 | Genesis Para La Investigacion | Procedimiento de obtencion de fluconazol. |
IL105200A (en) * | 1993-03-29 | 1997-03-18 | Teva Pharma | Regiospecific processes for the preparation of 1, 3-bis (1, 2, 4-triazol-1-yl)-propan- 2-ol derivatives |
HU212424B (en) * | 1993-09-23 | 1996-06-28 | Richter Gedeon Vegyeszet | New propan-2-ol derivatives substituted with triazole or imidazole and process for producing them |
SI9600165A (en) * | 1996-05-21 | 1997-12-31 | Krka Tovarna Zdravil D D Novo | Process for preparation of biological active derivative of 1,2,4- triazole and intermediates useful in this process |
WO2002076955A1 (en) * | 2001-03-23 | 2002-10-03 | Richter Gedeon Vegyeszéti Gyár Rt. | Process for preparing fluconazole and its crystal modifications |
IL165248A0 (en) * | 2002-06-24 | 2005-12-18 | Basf Ag | Method for the production of 1,2,4-triazolylmethyl-oxiranes |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR79307B (OSRAM) * | 1982-06-09 | 1984-10-22 | Pfizer | |
ES8604940A1 (es) * | 1985-11-19 | 1986-03-01 | Inke Sa | Procedimiento para la obtencion del 2-(2,4-difluorofenil)- 1,3-bis(1h-1,2,4-triazol-1-il)-propan-2-ol. |
ES8604938A1 (es) * | 1985-11-19 | 1986-03-01 | Inke Sa | Procedimiento para la obtencion del 2-(2,4-difluorofenil)- 1,3-bis(1h-1,2,4-triazol-1-il)-propan-2-ol |
ES8604939A1 (es) * | 1985-11-19 | 1986-03-01 | Inke Sa | Procedimiento para la obtencion del 2-(2,4-difluorofenil)- 1,3-bis(1h-1,2,4-triazol-1-il)-propan-2-ol |
ES8605753A1 (es) * | 1985-12-06 | 1986-04-16 | Lazlo Int Sa | Procedimiento de sintesis de un alcohol terciario |
-
1990
- 1990-06-08 IT IT02058690A patent/IT1249211B/it active IP Right Grant
- 1990-11-21 ES ES9002961A patent/ES2026416A6/es not_active Expired - Lifetime
-
1991
- 1991-06-05 AT AT113291A patent/AT400145B/de not_active IP Right Cessation
- 1991-06-06 YU YU101291A patent/YU48331B/sh unknown
- 1991-09-13 CA CA 2051281 patent/CA2051281C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IT9020586A0 (OSRAM) | 1990-06-07 |
IT9020586A1 (it) | 1991-12-08 |
AT400145B (de) | 1995-10-25 |
YU48331B (sh) | 1998-05-15 |
CA2051281C (en) | 1998-07-07 |
ATA113291A (de) | 1995-02-15 |
ES2026416A6 (es) | 1992-04-16 |
CA2051281A1 (en) | 1993-03-14 |
YU101291A (sh) | 1993-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970626 |