ES2020785A6 - Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona. - Google Patents

Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona.

Info

Publication number
ES2020785A6
ES2020785A6 ES9001949A ES9001949A ES2020785A6 ES 2020785 A6 ES2020785 A6 ES 2020785A6 ES 9001949 A ES9001949 A ES 9001949A ES 9001949 A ES9001949 A ES 9001949A ES 2020785 A6 ES2020785 A6 ES 2020785A6
Authority
ES
Spain
Prior art keywords
triazol
propan
bis
obtaining
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9001949A
Other languages
English (en)
Inventor
Barjoan Pere Dalmases
Rovira Ana Bosch
Ges Jose Maria Caldero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inke SA
Original Assignee
Inke SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inke SA filed Critical Inke SA
Priority to ES9001949A priority Critical patent/ES2020785A6/es
Publication of ES2020785A6 publication Critical patent/ES2020785A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE LA 1,3-BIS(1H-1,2,4-TRIAZOL-1-IL)-PROPAN-2-ONA. CONSISTE EN HACER REACCIONAR UN CETAL DE UNA 1,3-DIHALOACETONA DE FORMULA GENERAL III CON UNA SAL ALCALINA DEL 1H-1,2,4-TRIAZOL EN PRESENCIA DE UN DISOLVENTE ORGANICO Y UN CATALIZADOR ADECUADOS Y A UNA TEMPERATURA DE ENTRE 80GC Y 200GC, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL II, QUE SE AISLA COMO CLORHIDRATO Y SE SOMETE A CONDICIONES DE HIDROLISIS DEL GRUPO CETAL EN MEDIO ACIDO MINERAL CONCENTRADO. EL PRODUCTO OBTENIDO ES LA 1,3-BIS(1H-1,2,4-TRIAZOL-1-IL)-PROPAN-2-ONA, QUE SE APLICA COMO PRODUCTO INTERMEDIO PARA LA SINTESIS DE AGENTES ANTIFUNGICOS TRIAZOLICOS.
ES9001949A 1990-07-19 1990-07-19 Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona. Expired - Fee Related ES2020785A6 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9001949A ES2020785A6 (es) 1990-07-19 1990-07-19 Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9001949A ES2020785A6 (es) 1990-07-19 1990-07-19 Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona.

Publications (1)

Publication Number Publication Date
ES2020785A6 true ES2020785A6 (es) 1991-09-16

Family

ID=8268217

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9001949A Expired - Fee Related ES2020785A6 (es) 1990-07-19 1990-07-19 Procedimiento para la obtencion de la 1,3-bis (1h-1,2,4-triazol-1-il)-propan-2-ona.

Country Status (1)

Country Link
ES (1) ES2020785A6 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101891693A (zh) * 2010-08-05 2010-11-24 浙江金伯士药业有限公司 一种氟康唑的新制备方法
CN104557747A (zh) * 2015-02-05 2015-04-29 济南泺沣医药科技有限公司 一种氟康唑的制备方法

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101891693A (zh) * 2010-08-05 2010-11-24 浙江金伯士药业有限公司 一种氟康唑的新制备方法
CN101891693B (zh) * 2010-08-05 2013-03-13 浙江金伯士药业有限公司 一种氟康唑的制备方法
CN104557747A (zh) * 2015-02-05 2015-04-29 济南泺沣医药科技有限公司 一种氟康唑的制备方法
CN104557747B (zh) * 2015-02-05 2017-01-25 济南泺沣医药科技有限公司 一种氟康唑的制备方法

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Legal Events

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GC1A Exploitation certificate registered application without search report

Effective date: 19971127

GC1A Exploitation certificate registered application without search report

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Effective date: 20110223