IT1240598B - Derivati amminici ad azione antifungina - Google Patents

Derivati amminici ad azione antifungina

Info

Publication number
IT1240598B
IT1240598B IT19653A IT1965390A IT1240598B IT 1240598 B IT1240598 B IT 1240598B IT 19653 A IT19653 A IT 19653A IT 1965390 A IT1965390 A IT 1965390A IT 1240598 B IT1240598 B IT 1240598B
Authority
IT
Italy
Prior art keywords
alkyl
amine derivatives
halo
ranges
groups
Prior art date
Application number
IT19653A
Other languages
English (en)
Other versions
IT9019653A0 (it
IT9019653A1 (it
Inventor
Giovanni Camaggi
Lucio Filippini
Marilena Gusmeroli
Carlo Garavaglia
Luigi Mirenna
Original Assignee
Mini Ricerca Scient Tecnolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mini Ricerca Scient Tecnolog filed Critical Mini Ricerca Scient Tecnolog
Publication of IT9019653A0 publication Critical patent/IT9019653A0/it
Priority to IT19653A priority Critical patent/IT1240598B/it
Priority to IL9749991A priority patent/IL97499A/en
Priority to AU72794/91A priority patent/AU637204B2/en
Priority to NO910965A priority patent/NO179835C/no
Priority to DE69113659T priority patent/DE69113659T2/de
Priority to AT91103764T priority patent/ATE128963T1/de
Priority to BR919100971A priority patent/BR9100971A/pt
Priority to DK91103764.6T priority patent/DK0446873T3/da
Priority to CA002038076A priority patent/CA2038076A1/en
Priority to SU914894899A priority patent/RU2038353C1/ru
Priority to EP91103764A priority patent/EP0446873B1/en
Priority to ES91103764T priority patent/ES2078369T3/es
Priority to KR1019910004009A priority patent/KR100193159B1/ko
Priority to HU91822A priority patent/HU212751B/hu
Priority to ZA911850A priority patent/ZA911850B/xx
Priority to JP3073837A priority patent/JPH05310652A/ja
Publication of IT9019653A1 publication Critical patent/IT9019653A1/it
Priority to US08/001,919 priority patent/US5385892A/en
Application granted granted Critical
Publication of IT1240598B publication Critical patent/IT1240598B/it
Priority to GR950402936T priority patent/GR3017838T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N39/00—Biocides, pest repellants or attractants, or plant growth regulators containing aryloxy- or arylthio-aliphatic or cycloaliphatic compounds, containing the group or, e.g. phenoxyethylamine, phenylthio-acetonitrile, phenoxyacetone
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Health & Medical Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
IT19653A 1990-03-13 1990-03-13 Derivati amminici ad azione antifungina IT1240598B (it)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IT19653A IT1240598B (it) 1990-03-13 1990-03-13 Derivati amminici ad azione antifungina
IL9749991A IL97499A (en) 1990-03-13 1991-03-11 History of Morpholine Transformed their preparation and use as fungicides
AU72794/91A AU637204B2 (en) 1990-03-13 1991-03-11 Aminic derivatives showing fungicidal activity
CA002038076A CA2038076A1 (en) 1990-03-13 1991-03-12 Aminic derivatives showing fungicidal activity
DE69113659T DE69113659T2 (de) 1990-03-13 1991-03-12 Amine mit fungizider Wirkung.
AT91103764T ATE128963T1 (de) 1990-03-13 1991-03-12 Amine mit fungizider wirkung.
BR919100971A BR9100971A (pt) 1990-03-13 1991-03-12 Compostos,processo para preparacao dos compostos e compostos arila-propila-aminicos
DK91103764.6T DK0446873T3 (da) 1990-03-13 1991-03-12 Aminer med fungicid virkning
NO910965A NO179835C (no) 1990-03-13 1991-03-12 Aminderivater med fungicid aktivitet og anvendelse som fungicider
SU914894899A RU2038353C1 (ru) 1990-03-13 1991-03-12 Производные морфолина
EP91103764A EP0446873B1 (en) 1990-03-13 1991-03-12 Amines showing fungicidal activity
ES91103764T ES2078369T3 (es) 1990-03-13 1991-03-12 Aminas con actividad fungicida.
KR1019910004009A KR100193159B1 (ko) 1990-03-13 1991-03-13 살균 활성을 나타내는 아민 유도체
HU91822A HU212751B (en) 1990-03-13 1991-03-13 Fungicidal composition
ZA911850A ZA911850B (en) 1990-03-13 1991-03-13 Aminic derivatives showing fungicidal activity
JP3073837A JPH05310652A (ja) 1990-03-13 1991-03-13 殺真菌活性を示すアミン誘導体
US08/001,919 US5385892A (en) 1990-03-13 1993-01-04 Ethylamino phenyl ethers having antifungal activity
GR950402936T GR3017838T3 (en) 1990-03-13 1995-10-24 Amines showing fungicidal activity.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19653A IT1240598B (it) 1990-03-13 1990-03-13 Derivati amminici ad azione antifungina

Publications (3)

Publication Number Publication Date
IT9019653A0 IT9019653A0 (it) 1990-03-13
IT9019653A1 IT9019653A1 (it) 1991-09-13
IT1240598B true IT1240598B (it) 1993-12-17

Family

ID=11160100

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19653A IT1240598B (it) 1990-03-13 1990-03-13 Derivati amminici ad azione antifungina

Country Status (18)

Country Link
US (1) US5385892A (it)
EP (1) EP0446873B1 (it)
JP (1) JPH05310652A (it)
KR (1) KR100193159B1 (it)
AT (1) ATE128963T1 (it)
AU (1) AU637204B2 (it)
BR (1) BR9100971A (it)
CA (1) CA2038076A1 (it)
DE (1) DE69113659T2 (it)
DK (1) DK0446873T3 (it)
ES (1) ES2078369T3 (it)
GR (1) GR3017838T3 (it)
HU (1) HU212751B (it)
IL (1) IL97499A (it)
IT (1) IT1240598B (it)
NO (1) NO179835C (it)
RU (1) RU2038353C1 (it)
ZA (1) ZA911850B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050043379A1 (en) * 2003-07-28 2005-02-24 Axe Frank U. LTA4H Modulators
CL2008000468A1 (es) * 2007-02-14 2008-08-22 Janssen Pharmaceutica Nv Uso de compuestos derivados de heterociclos, inhibidores de leucotrina a4 hidrolasa (lta4h), utiles para tratar o prevenir la dermatitis, acne, infarto al miocardio, dolor, picazon, gingivitis, cancer, artritis, entre otras.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE167035C (it) *
DE1670635A1 (de) * 1967-09-06 1970-08-06 Eisai Co Ltd o-(ss-Morpholinoaethoxy) diphenylaether
US3988475A (en) * 1974-02-05 1976-10-26 Istituto Luso Farmaco D'italia S.R.L. Phenoxyalkylamines
CA1086733A (en) * 1976-12-06 1980-09-30 Ryoji Kikumoto Pharmaceutically active 2-substituted-1-(omega- aminoalkoxy) benzenes
GB2078217B (en) * 1980-06-14 1984-01-11 Beecham Group Ltd Phenolic ethers their preparation and use
US4393061A (en) * 1982-06-21 1983-07-12 Stiefel Laboratories, Inc. Anesthetic-antipruritic morpholine compounds, compositions and use
DE3410070A1 (de) * 1984-03-20 1985-10-03 Hoechst Ag, 6230 Frankfurt 1-(2-aryl-1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung, sie enthaltende zubereitungen und ihre verwendung
DK368687A (da) * 1986-11-21 1988-05-22 Cheminova As Aminoalkylerede hydroxyforbindelser og deres anvendelse som fungicider

Also Published As

Publication number Publication date
IL97499A (en) 1994-11-11
EP0446873B1 (en) 1995-10-11
HUT56482A (en) 1991-09-30
HU212751B (en) 1996-10-28
DE69113659T2 (de) 1996-04-04
IT9019653A0 (it) 1990-03-13
NO910965L (no) 1991-09-16
EP0446873A1 (en) 1991-09-18
IL97499A0 (en) 1992-06-21
RU2038353C1 (ru) 1995-06-27
CA2038076A1 (en) 1991-09-14
AU7279491A (en) 1991-09-19
BR9100971A (pt) 1991-11-05
NO179835C (no) 1996-12-27
AU637204B2 (en) 1993-05-20
JPH05310652A (ja) 1993-11-22
US5385892A (en) 1995-01-31
KR100193159B1 (ko) 1999-06-15
GR3017838T3 (en) 1996-01-31
DE69113659D1 (de) 1995-11-16
DK0446873T3 (da) 1996-02-19
ZA911850B (en) 1991-12-24
ES2078369T3 (es) 1995-12-16
NO910965D0 (no) 1991-03-12
ATE128963T1 (de) 1995-10-15
IT9019653A1 (it) 1991-09-13
NO179835B (no) 1996-09-16
KR910016729A (ko) 1991-11-05

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970313