IT1235053B - Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti. - Google Patents

Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti.

Info

Publication number
IT1235053B
IT1235053B IT8920063A IT2006389A IT1235053B IT 1235053 B IT1235053 B IT 1235053B IT 8920063 A IT8920063 A IT 8920063A IT 2006389 A IT2006389 A IT 2006389A IT 1235053 B IT1235053 B IT 1235053B
Authority
IT
Italy
Prior art keywords
preparation
bromocriptine
methods
pharmaceutical compositions
high stability
Prior art date
Application number
IT8920063A
Other languages
English (en)
Other versions
IT8920063A0 (it
Inventor
Luigi Moro
Achille Fiori
Alberto Natali
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of IT8920063A0 publication Critical patent/IT8920063A0/it
Priority to IT8920063A priority Critical patent/IT1235053B/it
Priority to US07/502,520 priority patent/US5066495A/en
Priority to DE199090106403T priority patent/DE391374T1/de
Priority to ES90106403T priority patent/ES2029776T3/es
Priority to DE69014691T priority patent/DE69014691T2/de
Priority to EP90106403A priority patent/EP0391374B1/en
Priority to AT90106403T priority patent/ATE114968T1/de
Priority to DK90106403.0T priority patent/DK0391374T3/da
Priority to DD33947390A priority patent/DD293961B5/de
Priority to GR90300172T priority patent/GR900300172T1/el
Application granted granted Critical
Publication of IT1235053B publication Critical patent/IT1235053B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8920063A 1989-04-07 1989-04-07 Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti. IT1235053B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT8920063A IT1235053B (it) 1989-04-07 1989-04-07 Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti.
US07/502,520 US5066495A (en) 1989-04-07 1990-03-30 Processes for the preparation of pharmaceutical compositions containing bromocriptine having high stability and related products
DE69014691T DE69014691T2 (de) 1989-04-07 1990-04-04 Verfahren zur Herstellung von Bromocriptin enthaltenden Arzneimittelzubereitungen mit hoher Stabilität und in Beziehung zueinander stehende Produkte.
ES90106403T ES2029776T3 (es) 1989-04-07 1990-04-04 Procedimiento para la preparacion de composiciones farmaceuticas que contienen bromocriptina con gran estabilidad y productos relacionados.
DE199090106403T DE391374T1 (de) 1989-04-07 1990-04-04 Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilitaet und in beziehung zueinander stehende produkte.
EP90106403A EP0391374B1 (en) 1989-04-07 1990-04-04 Processes for the preparation of pharmaceutical compositions containing bromocriptine having high stability and related products
AT90106403T ATE114968T1 (de) 1989-04-07 1990-04-04 Verfahren zur herstellung von bromocriptin enthaltenden arzneimittelzubereitungen mit hoher stabilität und in beziehung zueinander stehende produkte.
DK90106403.0T DK0391374T3 (da) 1989-04-07 1990-04-04 Fremgangsmåde til fremstilling af farmaceutiske præparater med høj stabilitet indeholdende bromocriptin, samt hertil svarende produkter
DD33947390A DD293961B5 (de) 1989-04-07 1990-04-05 Verfahren zur Herstellung von Tabletten und Kapseln
GR90300172T GR900300172T1 (en) 1989-04-07 1991-09-27 Processes for the preparation of pharmaceutical compositions containing bromocriptine having high stability and related products

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920063A IT1235053B (it) 1989-04-07 1989-04-07 Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti.

Publications (2)

Publication Number Publication Date
IT8920063A0 IT8920063A0 (it) 1989-04-07
IT1235053B true IT1235053B (it) 1992-06-17

Family

ID=11163518

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920063A IT1235053B (it) 1989-04-07 1989-04-07 Metodi per la preparazione di composizioni farmaceutiche a base di bromocriptina dotate di elevata stabilita' e prodotti derivanti.

Country Status (9)

Country Link
US (1) US5066495A (it)
EP (1) EP0391374B1 (it)
AT (1) ATE114968T1 (it)
DD (1) DD293961B5 (it)
DE (2) DE69014691T2 (it)
DK (1) DK0391374T3 (it)
ES (1) ES2029776T3 (it)
GR (1) GR900300172T1 (it)
IT (1) IT1235053B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2030174C (en) * 1990-01-10 1996-12-24 Anthony H. Cincotta Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates
US5292520A (en) * 1990-09-13 1994-03-08 Akzo N.V. Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
US5225204A (en) * 1991-11-05 1993-07-06 Chen Jivn Ren Stable dosage of levothyroxine sodium and process of production
IL112106A0 (en) * 1993-12-22 1995-03-15 Ergo Science Inc Accelerated release composition containing bromocriptine
SI9700186B (sl) * 1997-07-14 2006-10-31 Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin
US6129931A (en) * 1998-09-03 2000-10-10 Isp Investments Inc. Controlled-release, drug-delivery tableted composition including a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone
WO2003053292A1 (en) * 2001-12-20 2003-07-03 Femmepharma, Inc. Vaginal delivery of drugs
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
US9173836B2 (en) 2003-01-02 2015-11-03 FemmeParma Holding Company, Inc. Pharmaceutical preparations for treatments of diseases and disorders of the breast
JP2006515026A (ja) * 2003-01-02 2006-05-18 フェムファーマ ホールディング カンパニー， インコーポレイテッド 乳房の疾患および障害の処置のための薬学的調製物
AU2007216882B2 (en) * 2003-01-02 2010-03-11 Femmepharma Holding Company, Inc. Pharmaceutical preparations for treatment of diseases and disorders of the breast
US20080153789A1 (en) * 2006-12-26 2008-06-26 Femmepharma Holding Company, Inc. Topical administration of danazol
GB0715628D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Solid valsartan composition
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US20110003000A1 (en) * 2009-07-06 2011-01-06 Femmepharma Holding Company, Inc. Transvaginal Delivery of Drugs
US8431155B1 (en) * 2012-04-30 2013-04-30 Veroscience Llc Bromocriptine formulations
CN105640901A (zh) * 2014-11-10 2016-06-08 匈牙利吉瑞大药厂 一种利用新型生产工艺制备甲磺酸溴隐亭片的方法及其应用
PL3445362T3 (pl) 2016-04-20 2022-05-30 Veroscience Llc Kompozycja i sposób leczenia zaburzeń metabolicznych
HRP20241365T1 (hr) 2017-10-18 2024-12-20 Veroscience Llc Poboljšane formulacije bromokriptina
WO2021061818A1 (en) 2019-09-23 2021-04-01 Veroscience Llc Method for inducing tumor regression
CN117323305B (zh) * 2023-11-07 2024-06-07 杭州沐源生物医药科技有限公司 溴隐亭片剂及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL113512C (it) * 1962-01-25
US3836618A (en) * 1971-12-23 1974-09-17 American Home Prod Process for the uniform distribution of a drug on a granulated base
NL7314066A (it) * 1972-10-18 1974-04-22
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
US4479911A (en) * 1982-01-28 1984-10-30 Sandoz, Inc. Process for preparation of microspheres and modification of release rate of core material
NO832446L (no) * 1982-07-06 1984-01-30 Sterwin Ag, Fremgangsmaate ved fremstilling av tabletter.
US4742054A (en) * 1982-11-23 1988-05-03 Naftchi Nosrat E Treatment of mammals suffering from damage to the central nervous system
GB2154874B (en) * 1984-02-29 1987-11-04 Sandoz Ltd Bromoscriptine compositions

Also Published As

Publication number Publication date
EP0391374B1 (en) 1994-12-07
EP0391374A3 (en) 1992-07-01
US5066495A (en) 1991-11-19
IT8920063A0 (it) 1989-04-07
DE69014691T2 (de) 1995-04-20
ES2029776T3 (es) 1995-02-01
GR900300172T1 (en) 1991-09-27
DK0391374T3 (da) 1995-04-24
EP0391374A2 (en) 1990-10-10
ES2029776T1 (es) 1992-10-01
ATE114968T1 (de) 1994-12-15
DD293961B5 (de) 1994-11-10
DE69014691D1 (de) 1995-01-19
DE391374T1 (de) 1991-02-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950427