IT1228242B - Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengono - Google Patents
Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengonoInfo
- Publication number
- IT1228242B IT1228242B IT8622320A IT2232086A IT1228242B IT 1228242 B IT1228242 B IT 1228242B IT 8622320 A IT8622320 A IT 8622320A IT 2232086 A IT2232086 A IT 2232086A IT 1228242 B IT1228242 B IT 1228242B
- Authority
- IT
- Italy
- Prior art keywords
- pharmaceutical compositions
- hydroxyethylpyrrolidine
- contain
- salt
- diclofenac
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8622320A IT1228242B (it) | 1986-11-13 | 1986-11-13 | Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengono |
DE8787116513T DE3769943D1 (de) | 1986-11-13 | 1987-11-09 | Salz von diclofenac mit einer cyclisch organischen base und pharmazeutische zusammensetzungen, die es enthalten. |
EP87116513A EP0271709B1 (en) | 1986-11-13 | 1987-11-09 | Salt of diclofenac with a cyclic organic base and pharmaceutical compositions which contain it |
ZA878405A ZA878405B (en) | 1986-11-13 | 1987-11-09 | Salt of diclofenac with a cyclic organic base and pharmaceutical compositions which contain it |
ES198787116513T ES2029254T3 (es) | 1986-11-13 | 1987-11-09 | Procedimiento para la preparacion de una sal de diclofenac con una base organica ciclica. |
AT87116513T ATE63304T1 (de) | 1986-11-13 | 1987-11-09 | Salz von diclofenac mit einer cyclisch organischen base und pharmazeutische zusammensetzungen, die es enthalten. |
US07/117,823 US4948805A (en) | 1986-11-13 | 1987-11-09 | Salt of diclofenac with a pyrrolidine compound and pharmaceutical compositions which contain it |
IE873006A IE873006L (en) | 1986-11-13 | 1987-11-09 | Salt of diclofenac with a cyclic organic base and¹pharmaceutical compositions which contain it |
PT86121A PT86121B (pt) | 1986-11-13 | 1987-11-12 | Processo para a preparacao de sal de acido 2-{(2,6-diclorofenil)-amino}-benzeno-acetico com uma base organica ciclica e de composicoes farmaceuticas contendo o mesmo |
NO874733A NO874733L (no) | 1986-11-13 | 1987-11-12 | Salt av diclofenac med en cyklisk organisk base, og farmasoeytiske preparater inneholdende dette. |
AU81175/87A AU8117587A (en) | 1986-11-13 | 1987-11-12 | Salt of diclofenac with cyclic organic base and pharmaceutical compositions which contain it |
CA000551717A CA1303050C (en) | 1986-11-13 | 1987-11-12 | Salt of diclofenac with a cyclic organic base and pharmaceutical compositions which contain it |
DK592987A DK592987A (da) | 1986-11-13 | 1987-11-12 | Salte af 2-oe(2,6-dichlorphenyl)-aminoaa-benzeneddikesyre med cycliske organiske baser samt farmaceutiske midler indeholdende saadanne salte |
KR1019870012712A KR960003327B1 (ko) | 1986-11-13 | 1987-11-12 | 디클로페낙과 환상 유기염기와의 염 및 이를 함유한 약학적 조성물 |
FI875023A FI875023A (fi) | 1986-11-13 | 1987-11-13 | Salt av diklofenak och en cyklisk organisk bas och farmaceutiska kompositioner innehaollande detsamma. |
JP62285664A JPS63152372A (ja) | 1986-11-13 | 1987-11-13 | ジクロフェナックと環状有機塩基との塩,およびそれを含有する薬剤組成物 |
GR91401092T GR3002386T3 (en) | 1986-11-13 | 1991-07-25 | Salt of diclofenac with a cyclic organic base and pharmaceutical compositions which contain it |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8622320A IT1228242B (it) | 1986-11-13 | 1986-11-13 | Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengono |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8622320A0 IT8622320A0 (it) | 1986-11-13 |
IT1228242B true IT1228242B (it) | 1991-06-05 |
Family
ID=11194630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8622320A IT1228242B (it) | 1986-11-13 | 1986-11-13 | Sale del diclofenac con idrossietilpirrolidina e composizioni farmaceutiche che lo contengono |
Country Status (17)
Country | Link |
---|---|
US (1) | US4948805A (it) |
EP (1) | EP0271709B1 (it) |
JP (1) | JPS63152372A (it) |
KR (1) | KR960003327B1 (it) |
AT (1) | ATE63304T1 (it) |
AU (1) | AU8117587A (it) |
CA (1) | CA1303050C (it) |
DE (1) | DE3769943D1 (it) |
DK (1) | DK592987A (it) |
ES (1) | ES2029254T3 (it) |
FI (1) | FI875023A (it) |
GR (1) | GR3002386T3 (it) |
IE (1) | IE873006L (it) |
IT (1) | IT1228242B (it) |
NO (1) | NO874733L (it) |
PT (1) | PT86121B (it) |
ZA (1) | ZA878405B (it) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1229489B (it) * | 1988-12-09 | 1991-09-03 | Altergon Sa | Composizioni farmaceutiche lipidiche per uso topico atte a veicolare un principio attivo antiinfiammatorio idrosolubile |
CA2095127C (en) * | 1990-11-19 | 1998-06-30 | Albemarle Corporation | Process for improving flow characteristics of crystalline ibuprofen |
IT1255007B (it) * | 1991-07-01 | 1995-10-11 | Altergon Sa | Sale solubile dell'ibuprofen c0n n-(2-idrossietil) pirrolidina e composizioni farmaceutiche che li contengono. |
JP3526887B2 (ja) * | 1993-04-23 | 2004-05-17 | 帝國製薬株式会社 | 消炎鎮痛外用貼付剤 |
US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
DE4403943A1 (de) * | 1994-02-08 | 1995-08-10 | Hexal Pharma Gmbh | Orale Azrneimittelzubereitung mit Diclofenac-Natrium |
PL318014A1 (en) * | 1994-06-29 | 1997-05-12 | Ciba Geigy Ag | Novel 2-[(2,6-dichlorophenyl)amino]phenyloaacetoxyacetic salts with cations of organic bases |
US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
ITMI20030269A1 (it) * | 2003-02-14 | 2004-08-15 | Advance Holdings Ltd | Sale di cetilpiridino di un agente antiinfiammatorio |
US7943668B2 (en) * | 2008-03-03 | 2011-05-17 | Altergon S.A. | Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus obtained |
WO2010069397A1 (en) * | 2008-12-19 | 2010-06-24 | Cosma S.P.A. | Process for the preparation of diclofenac epolamine |
TWI482645B (zh) | 2010-01-07 | 2015-05-01 | Teikoku Seiyaku Kk | 含有待克菲那(diclofenac)羥乙基吡咯啶之外用油性敷貼劑 |
ITMI20121205A1 (it) | 2012-07-11 | 2014-01-12 | Glycores 2000 Srl | Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione |
WO2021048748A1 (en) | 2019-09-09 | 2021-03-18 | Ftf Pharma Private Limited | Pharmaceutical formulations comprising diclofenac |
IT202100016751A1 (it) | 2021-06-25 | 2022-12-25 | Altergon Sa | Formulazione topica di diclofenac ad elevato tasso di assorbimento |
WO2023180792A1 (en) | 2022-03-25 | 2023-09-28 | Glycores 2000 Srl | Topical pharmaceutical composition with anti-inflammatory and analgesic activity and uses thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
LU83138A1 (de) * | 1981-02-16 | 1981-09-11 | T Eckert | Topische pharmazeutische praeparate,enthaltend salze von alkancarbonsaeuren sowie neue carbonsaeuresalze und verfahren zu ihrer herstellung |
-
1986
- 1986-11-13 IT IT8622320A patent/IT1228242B/it active
-
1987
- 1987-11-09 ES ES198787116513T patent/ES2029254T3/es not_active Expired - Lifetime
- 1987-11-09 EP EP87116513A patent/EP0271709B1/en not_active Expired - Lifetime
- 1987-11-09 ZA ZA878405A patent/ZA878405B/xx unknown
- 1987-11-09 AT AT87116513T patent/ATE63304T1/de not_active IP Right Cessation
- 1987-11-09 IE IE873006A patent/IE873006L/xx unknown
- 1987-11-09 US US07/117,823 patent/US4948805A/en not_active Expired - Lifetime
- 1987-11-09 DE DE8787116513T patent/DE3769943D1/de not_active Expired - Fee Related
- 1987-11-12 AU AU81175/87A patent/AU8117587A/en not_active Abandoned
- 1987-11-12 CA CA000551717A patent/CA1303050C/en not_active Expired - Fee Related
- 1987-11-12 PT PT86121A patent/PT86121B/pt not_active IP Right Cessation
- 1987-11-12 KR KR1019870012712A patent/KR960003327B1/ko not_active IP Right Cessation
- 1987-11-12 NO NO874733A patent/NO874733L/no unknown
- 1987-11-12 DK DK592987A patent/DK592987A/da not_active Application Discontinuation
- 1987-11-13 FI FI875023A patent/FI875023A/fi not_active Application Discontinuation
- 1987-11-13 JP JP62285664A patent/JPS63152372A/ja active Granted
-
1991
- 1991-07-25 GR GR91401092T patent/GR3002386T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA878405B (en) | 1988-05-05 |
CA1303050C (en) | 1992-06-09 |
KR880006218A (ko) | 1988-07-22 |
US4948805A (en) | 1990-08-14 |
NO874733L (no) | 1988-05-16 |
EP0271709B1 (en) | 1991-05-08 |
DK592987D0 (da) | 1987-11-12 |
NO874733D0 (no) | 1987-11-12 |
PT86121B (pt) | 1990-08-31 |
JPS63152372A (ja) | 1988-06-24 |
FI875023A0 (fi) | 1987-11-13 |
ATE63304T1 (de) | 1991-05-15 |
AU8117587A (en) | 1988-05-19 |
GR3002386T3 (en) | 1992-12-30 |
FI875023A (fi) | 1988-05-14 |
PT86121A (en) | 1987-12-01 |
DE3769943D1 (de) | 1991-06-13 |
ES2029254T3 (es) | 1992-08-01 |
EP0271709A1 (en) | 1988-06-22 |
KR960003327B1 (ko) | 1996-03-08 |
DK592987A (da) | 1988-05-14 |
IT8622320A0 (it) | 1986-11-13 |
JPH0344062B2 (it) | 1991-07-04 |
IE873006L (en) | 1988-05-13 |
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