IT1217567B - Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici - Google Patents

Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici

Info

Publication number
IT1217567B
IT1217567B IT20542/88A IT2054288A IT1217567B IT 1217567 B IT1217567 B IT 1217567B IT 20542/88 A IT20542/88 A IT 20542/88A IT 2054288 A IT2054288 A IT 2054288A IT 1217567 B IT1217567 B IT 1217567B
Authority
IT
Italy
Prior art keywords
synthesis
preparation
peptidal
derivatives
useful intermediates
Prior art date
Application number
IT20542/88A
Other languages
English (en)
Other versions
IT8820542A0 (it
Inventor
Franco Pellacini
Dario Chiarino
Angelo Carenzi
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Priority to IT20542/88A priority Critical patent/IT1217567B/it
Publication of IT8820542A0 publication Critical patent/IT8820542A0/it
Priority to ES89107141T priority patent/ES2052801T3/es
Priority to DE8989107141T priority patent/DE68902771T2/de
Priority to EP89107141A priority patent/EP0341462B1/en
Priority to AT89107141T priority patent/ATE80380T1/de
Priority to US07/350,462 priority patent/US5157143A/en
Priority to JP1118483A priority patent/JP2860559B2/ja
Application granted granted Critical
Publication of IT1217567B publication Critical patent/IT1217567B/it
Priority to GR920402796T priority patent/GR3006432T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/32—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT20542/88A 1988-05-11 1988-05-11 Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici IT1217567B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT20542/88A IT1217567B (it) 1988-05-11 1988-05-11 Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici
ES89107141T ES2052801T3 (es) 1988-05-11 1989-04-20 Procedimiento diastereoselectivo para la preparacion de intermediarios utiles para la sintesis de derivados peptidicos.
DE8989107141T DE68902771T2 (de) 1988-05-11 1989-04-20 Diastereoselektives verfahren zur herstellung von zwischenprodukten verwendbar zur peptidderivatensynthese.
EP89107141A EP0341462B1 (en) 1988-05-11 1989-04-20 Diastereoselective process for the preparation of intermediates useful for the synthesis of peptide derivatives
AT89107141T ATE80380T1 (de) 1988-05-11 1989-04-20 Diastereoselektives verfahren zur herstellung von zwischenprodukten verwendbar zur peptidderivatensynthese.
US07/350,462 US5157143A (en) 1988-05-11 1989-05-11 Diastereoselective process for the preparation of intermediates useful for the synthesis of peptide derivatives
JP1118483A JP2860559B2 (ja) 1988-05-11 1989-05-11 ペプチド誘導体合成に有用な立体特異性中間体の製法
GR920402796T GR3006432T3 (it) 1988-05-11 1992-12-02

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20542/88A IT1217567B (it) 1988-05-11 1988-05-11 Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici

Publications (2)

Publication Number Publication Date
IT8820542A0 IT8820542A0 (it) 1988-05-11
IT1217567B true IT1217567B (it) 1990-03-30

Family

ID=11168517

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20542/88A IT1217567B (it) 1988-05-11 1988-05-11 Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici

Country Status (8)

Country Link
US (1) US5157143A (it)
EP (1) EP0341462B1 (it)
JP (1) JP2860559B2 (it)
AT (1) ATE80380T1 (it)
DE (1) DE68902771T2 (it)
ES (1) ES2052801T3 (it)
GR (1) GR3006432T3 (it)
IT (1) IT1217567B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648511A (en) * 1990-11-19 1997-07-15 G.D. Searle & Co. Method for making intermediates useful in the synthesis of retroviral protease inhibitors
US6743929B1 (en) * 1992-08-25 2004-06-01 G. D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
ATE284863T1 (de) * 1996-02-08 2005-01-15 Nippon Kayaku Kk Verfahren zur erzeugung optisch aktiver cyanohydrine
JP2001048850A (ja) * 1999-05-28 2001-02-20 Kanegafuchi Chem Ind Co Ltd ノルスタチン誘導体の製造法
JP2002047256A (ja) * 2000-07-26 2002-02-12 Kanegafuchi Chem Ind Co Ltd α−アミノ−α´，α´，α´−トリハロケトン誘導体、α−アミノ−α´，α´，α´−トリハロアルコ−ル誘導体、及び、α−ヒドロキシ−β−アミノカルボン酸誘導体の製造法
WO2007029587A1 (ja) 2005-09-05 2007-03-15 Dainippon Sumitomo Pharma Co., Ltd. βセクレターゼ阻害剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2090595B (en) * 1978-11-25 1983-05-11 Nippon Kayaku Kk Threo-3-amino-2-hydroxybutanoylacetice acid derivatives
JPS6033439B2 (ja) * 1980-03-07 1985-08-02 財団法人相模中央化学研究所 ジペプチドの製造方法

Also Published As

Publication number Publication date
EP0341462B1 (en) 1992-09-09
EP0341462A1 (en) 1989-11-15
US5157143A (en) 1992-10-20
ES2052801T3 (es) 1994-07-16
JP2860559B2 (ja) 1999-02-24
GR3006432T3 (it) 1993-06-21
DE68902771D1 (de) 1992-10-15
JPH0228144A (ja) 1990-01-30
IT8820542A0 (it) 1988-05-11
ATE80380T1 (de) 1992-09-15
DE68902771T2 (de) 1993-01-07

Similar Documents

Publication Publication Date Title
AU694417B2 (en) Cyclic ureas and analogues useful as retroviral protease inhibitiors
AU643489B2 (en) Antibacterial agents - II
IT1217567B (it) Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici
NO173444C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive 4-(4'- fluorfenyl-)-tienopyridin-derivater
DE3887362D1 (de) Thymopentin-Retro-Inverso-Analoga und deren Fragmente, Verfahren zu deren Herstellung und so erhaltene Zwischenprodukte.
HUT70052A (en) Process for producing pharmaceutical compositions containing pirimidone derivatives in the treatment of certain airway or skin diseases
HUT55349A (en) Process for producing benzanilide derivatives and pharmaceutical compositions comprising same
FI893682A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 1,2,5-ditiatsosiinijohdannaisten valmistamiseksi
PT89492A (pt) Processo de preparacao de novos derivados de tioformamida terapeuticamente activos
NO159927C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aromatiske aminoacetylener.
EP0802179A4 (en) DERIVATE SUBSTITUTED AMIDINONAPHTHYLESTER
DE69114911D1 (de) Verfahren zur Herstellung von optisch-aktivem Zyklobutanon, ein Zwischenprodukt in der Synthese von optisch-aktiven Zyklobutanonnukleosiden.
DK0492350T3 (da) Fremgangsmåde til fremstilling af (S)-vinyl- og (S)-allenyl-GABA
AU7453487A (en) Cis and trans stilbenes
AU3375893A (en) Intermediates of n-hydroxy-dibenz(b,e)oxepin-alkylamines and -alkanoic acid amides, related heterocyclic analogues, a process for their preparation and their use as medicaments
AU657423B2 (en) Novel piperidine derivatives and process for preparation thereof
LU88449I2 (fr) Fleroxacine et ses dérivés pharmaceutiquement acceptables.
EP0412061A3 (en) 2-(n-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same