IT1212900B - Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna - Google Patents

Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna

Info

Publication number
IT1212900B
IT1212900B IT49355/83A IT4935583A IT1212900B IT 1212900 B IT1212900 B IT 1212900B IT 49355/83 A IT49355/83 A IT 49355/83A IT 4935583 A IT4935583 A IT 4935583A IT 1212900 B IT1212900 B IT 1212900B
Authority
IT
Italy
Prior art keywords
phosphatidylserine
nervous system
central nervous
effects
diseases
Prior art date
Application number
IT49355/83A
Other languages
English (en)
Other versions
IT8349355A0 (it
Inventor
Valle Francesco Della
Aurelio Romeo
Original Assignee
Valle Francesco Della
Aurelio Romeo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valle Francesco Della, Aurelio Romeo filed Critical Valle Francesco Della
Publication of IT8349355A0 publication Critical patent/IT8349355A0/it
Priority to IT49355/83A priority Critical patent/IT1212900B/it
Priority to US06/599,341 priority patent/US4595680A/en
Priority to IE278584A priority patent/IE58130B1/en
Priority to NZ210091A priority patent/NZ210091A/xx
Priority to DK524884A priority patent/DK168271B1/da
Priority to IN767/CAL/84A priority patent/IN162717B/en
Priority to IL73420A priority patent/IL73420A/xx
Priority to ZA848776A priority patent/ZA848776B/xx
Priority to ES537575A priority patent/ES8608528A1/es
Priority to LU85639A priority patent/LU85639A1/fr
Priority to FR8417262A priority patent/FR2555050B1/fr
Priority to FI844468A priority patent/FI79946C/fi
Priority to JP59242174A priority patent/JPH0676334B2/ja
Priority to MX203403A priority patent/MX160792A/es
Priority to GR80951A priority patent/GR80951B/el
Priority to CH5471/84A priority patent/CH661734A5/fr
Priority to HU844269A priority patent/HU193302B/hu
Priority to AT84402340T priority patent/ATE35415T1/de
Priority to PT79510A priority patent/PT79510B/pt
Priority to AU35630/84A priority patent/AU572228B2/en
Priority to EP84402340A priority patent/EP0148045B1/en
Priority to DE8484402340T priority patent/DE3472406D1/de
Priority to BE0/214020A priority patent/BE901074A/nl
Priority to NO844585A priority patent/NO164275C/no
Priority to KR1019840007230A priority patent/KR870001330B1/ko
Application granted granted Critical
Publication of IT1212900B publication Critical patent/IT1212900B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Epoxy Resins (AREA)
  • Heat Treatment Of Steel (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT49355/83A 1983-11-17 1983-11-17 Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna IT1212900B (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
IT49355/83A IT1212900B (it) 1983-11-17 1983-11-17 Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna
US06/599,341 US4595680A (en) 1983-11-17 1984-04-12 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
IE278584A IE58130B1 (en) 1983-11-17 1984-10-30 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
NZ210091A NZ210091A (en) 1983-11-17 1984-11-02 Phosphatidylserine compositions and their preparation
DK524884A DK168271B1 (da) 1983-11-17 1984-11-02 Farmaceutiske præparater indeholdende phosphatidylserin og fremgangsmåde til fremstilling deraf
IN767/CAL/84A IN162717B (it) 1983-11-17 1984-11-02
IL73420A IL73420A (en) 1983-11-17 1984-11-05 Phosphatidylserine and phosphatidylethanol amine compositions for treating central nervous system disorders
ZA848776A ZA848776B (en) 1983-11-17 1984-11-09 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
ES537575A ES8608528A1 (es) 1983-11-17 1984-11-12 Procedimiento para la fabricacion de fosfatidilserina para el tratamiento de desordenes del sistema nervioso central
LU85639A LU85639A1 (fr) 1983-11-17 1984-11-13 Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang
FR8417262A FR2555050B1 (fr) 1983-11-17 1984-11-13 Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine, utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang
FI844468A FI79946C (fi) 1983-11-17 1984-11-14 Foerfarande foer framstaellning av fosfolipid-sammansaettning anvaendbara vid behandling av sjukdomar i det centrala nervsystemet.
JP59242174A JPH0676334B2 (ja) 1983-11-17 1984-11-15 ホスファチジルセリン医薬組成物
MX203403A MX160792A (es) 1983-11-17 1984-11-15 Metodo mejorado para la preparacion de una composicion de fosfolipidos
GR80951A GR80951B (en) 1983-11-17 1984-11-15 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
CH5471/84A CH661734A5 (fr) 1983-11-17 1984-11-15 Procede de preparation de compositions de phospholipides utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang.
AU35630/84A AU572228B2 (en) 1983-11-17 1984-11-16 Phosphatidyl serine compositions for cns disorders
AT84402340T ATE35415T1 (de) 1983-11-17 1984-11-16 Pharmazeutische zusammensetzungen und verfahren fuer die herstellung von zusammensetzungen mit gehalt an phosphatidylserine zur behandlung von stoerungen des centralen nervensystems ohne wirkungen auf die blutkoagulation.
PT79510A PT79510B (en) 1983-11-17 1984-11-16 Phosphatidylserine compositions
HU844269A HU193302B (en) 1983-11-17 1984-11-16 Process for producing phospholipide compositions and pharmaceutical compositions containing them as active agents
EP84402340A EP0148045B1 (en) 1983-11-17 1984-11-16 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
DE8484402340T DE3472406D1 (en) 1983-11-17 1984-11-16 Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation
BE0/214020A BE901074A (nl) 1983-11-17 1984-11-16 Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang.
NO844585A NO164275C (no) 1983-11-17 1984-11-16 Fremgangsmaate for fremstilling av et fosfolipid-preparat.
KR1019840007230A KR870001330B1 (ko) 1983-11-17 1984-11-17 포스포리피드 조성물의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49355/83A IT1212900B (it) 1983-11-17 1983-11-17 Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna

Publications (2)

Publication Number Publication Date
IT8349355A0 IT8349355A0 (it) 1983-11-17
IT1212900B true IT1212900B (it) 1989-11-30

Family

ID=11270453

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49355/83A IT1212900B (it) 1983-11-17 1983-11-17 Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna

Country Status (25)

Country Link
US (1) US4595680A (it)
EP (1) EP0148045B1 (it)
JP (1) JPH0676334B2 (it)
KR (1) KR870001330B1 (it)
AT (1) ATE35415T1 (it)
AU (1) AU572228B2 (it)
BE (1) BE901074A (it)
CH (1) CH661734A5 (it)
DE (1) DE3472406D1 (it)
DK (1) DK168271B1 (it)
ES (1) ES8608528A1 (it)
FI (1) FI79946C (it)
FR (1) FR2555050B1 (it)
GR (1) GR80951B (it)
HU (1) HU193302B (it)
IE (1) IE58130B1 (it)
IL (1) IL73420A (it)
IN (1) IN162717B (it)
IT (1) IT1212900B (it)
LU (1) LU85639A1 (it)
MX (1) MX160792A (it)
NO (1) NO164275C (it)
NZ (1) NZ210091A (it)
PT (1) PT79510B (it)
ZA (1) ZA848776B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471776A1 (fr) * 1979-12-21 1981-06-26 Oreal Nouveaux agents cosmetiques a base de polymeres cationiques, compositions cosmetiques les contenant, et leur application
IT1213034B (it) * 1986-02-12 1989-12-07 Istituto Chemioterapico Di Lod Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale.
US5314695A (en) * 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
FR2673512B1 (fr) * 1991-03-05 1993-08-20 Inst Rech Biolog Sa Nouvelles compositions dietetiques a base de lipides complexes phosphores et leur utilisation dans les troubles du sommeil.
IT1247165B (it) * 1991-03-15 1994-12-12 Fidia Spa Uso terapeutico della fosfatidilserina e derivati in patologie degenerative anche associate a disfunsioni immunitarie.
IT1248012B (it) * 1991-06-07 1995-01-05 Mediolanum Farmaceutici Spa Impiego del fosfatidilinositolo per la terapia dei disturbi della depressione.
IT1260149B (it) * 1992-04-17 1996-03-28 Fidia Spa Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali
GB9621293D0 (en) * 1996-10-11 1996-11-27 Scotia Holdings Plc Formulations containing unsaturated fatty acids
CA2393595A1 (en) * 1999-12-10 2001-06-14 Gigi Chiu Lipid carrier compositions with protected surface reactive functions
US7226916B1 (en) 2000-05-08 2007-06-05 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
TWI281407B (en) * 2000-09-18 2007-05-21 Vasogen Ireland Ltd Apoptosis-mimicking synthetic entities and use thereof in medical treatment
CA2319928A1 (en) * 2000-09-18 2002-03-18 Vasogen Ireland Limited Apoptosis-mimicking synthetic entities and use thereof in medical treatments
US6676963B1 (en) * 2000-10-27 2004-01-13 Barnes-Jewish Hospital Ligand-targeted emulsions carrying bioactive agents
EP1414469A2 (de) * 2001-08-09 2004-05-06 Degussa Food Ingredient GmbH Formulierung enthaltend (lyso-) phosphatidylserin zur vorbeugung und behandlung von stresszuständen bei warmblütern
WO2003088949A2 (de) * 2002-04-19 2003-10-30 Bioghurt Biogarde Gmbh & Co. Kg. Matrix mit einer bioaktiven phospholipid-haltigen komponente
US6878532B1 (en) 2003-04-28 2005-04-12 Sioux Biochemical, Inc. Method of producing phosphatidylserine
CN1308334C (zh) * 2004-06-01 2007-04-04 山东师范大学 一种从动物脑提取磷脂酰丝氨酸的方法
IL182372A0 (en) * 2007-04-01 2008-01-20 Enzymotec Ltd Compositions containing phosphatidylserine in treating diabetes-associated conditions
ITMI20121784A1 (it) * 2012-10-22 2014-04-23 Velleja Res Srl Composizioni galattogeniche a base di fosfatidilserina
WO2015069870A1 (en) * 2013-11-07 2015-05-14 The University Of North Carolina At Chapel Hill Particles containing phospholipids or bioactive fatty acid
IT202100032252A1 (it) * 2021-12-22 2023-06-22 Fidia Farm Spa Processo di estrazione e purificazione industriale di fosfolipidi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3156616A (en) * 1958-11-14 1964-11-10 Canada Majesty In Right Of Composition and method for correcting foods and blood conditions having clot promoting characteristics
US3436413A (en) * 1965-12-21 1969-04-01 Canada Packers Ltd Process for the isolation of phosphatidyl serine
FR5060M (it) * 1965-12-22 1967-05-08
US4078052A (en) * 1976-06-30 1978-03-07 The United States Of America As Represented By The Secretary Of Health, Education And Welfare Large unilamellar vesicles (LUV) and method of preparing same
JPS55115824A (en) * 1979-02-28 1980-09-06 Nippon Shoji Kk Remedy for clouding of consciousness and sensomobile disorder

Also Published As

Publication number Publication date
LU85639A1 (fr) 1985-06-04
BE901074A (nl) 1985-05-17
KR870001330B1 (ko) 1987-07-18
IL73420A0 (en) 1985-02-28
FR2555050A1 (fr) 1985-05-24
EP0148045A1 (en) 1985-07-10
DE3472406D1 (en) 1988-08-04
DK524884D0 (da) 1984-11-02
JPH0676334B2 (ja) 1994-09-28
CH661734A5 (fr) 1987-08-14
HUT35957A (en) 1985-08-28
FI844468L (fi) 1985-05-18
NZ210091A (en) 1988-06-30
ZA848776B (en) 1986-06-25
NO164275B (no) 1990-06-11
ES537575A0 (es) 1986-07-16
EP0148045B1 (en) 1988-06-29
IE842785L (en) 1985-05-17
PT79510A (en) 1984-12-01
IN162717B (it) 1988-07-02
AU3563084A (en) 1985-05-30
NO844585L (no) 1985-05-20
ES8608528A1 (es) 1986-07-16
KR850003504A (ko) 1985-06-20
FI79946C (fi) 1990-04-10
IL73420A (en) 1988-06-30
JPS60132921A (ja) 1985-07-16
ATE35415T1 (de) 1988-07-15
IT8349355A0 (it) 1983-11-17
HU193302B (en) 1987-09-28
FI844468A0 (fi) 1984-11-14
NO164275C (no) 1990-09-19
DK168271B1 (da) 1994-03-07
MX160792A (es) 1990-05-17
GR80951B (en) 1984-12-18
IE58130B1 (en) 1993-07-14
FI79946B (fi) 1989-12-29
DK524884A (da) 1985-05-18
PT79510B (en) 1986-09-08
FR2555050B1 (fr) 1986-12-26
US4595680A (en) 1986-06-17
AU572228B2 (en) 1988-05-05

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950925