IT1260149B - Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali - Google Patents

Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali

Info

Publication number
IT1260149B
IT1260149B ITPD920073A ITPD920073A IT1260149B IT 1260149 B IT1260149 B IT 1260149B IT PD920073 A ITPD920073 A IT PD920073A IT PD920073 A ITPD920073 A IT PD920073A IT 1260149 B IT1260149 B IT 1260149B
Authority
IT
Italy
Prior art keywords
phospholipids
mixtures
contaminants
purification
preparation
Prior art date
Application number
ITPD920073A
Other languages
English (en)
Inventor
Lanfranco Callegaro
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Priority to ITPD920073A priority Critical patent/IT1260149B/it
Publication of ITPD920073A0 publication Critical patent/ITPD920073A0/it
Priority to PCT/EP1993/000915 priority patent/WO1993021190A1/en
Priority to DE69308834T priority patent/DE69308834D1/de
Priority to EP93911469A priority patent/EP0638083B1/en
Priority to AT93911469T priority patent/ATE150025T1/de
Publication of ITPD920073A1 publication Critical patent/ITPD920073A1/it
Application granted granted Critical
Publication of IT1260149B publication Critical patent/IT1260149B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invenzione descrive il processo per l'ottenimento di miscele di fosfolipidi che elimina selettivamente contaminanti associati a virus non convenzionali potenzialmente pericolosi per la salute dell'uomo, senza alterare le caratteristiche biologiche e farmacologiche
ITPD920073A 1992-04-17 1992-04-17 Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali IT1260149B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITPD920073A IT1260149B (it) 1992-04-17 1992-04-17 Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali
PCT/EP1993/000915 WO1993021190A1 (en) 1992-04-17 1993-04-16 Method for the preparation and purification of phospholipid mixtures free from contamination by unconventional viruses
DE69308834T DE69308834D1 (de) 1992-04-17 1993-04-16 Verfahren zur herstellung und reinigung von phospholipidmischungen frei von kontaminierenden unkonventionellen viren
EP93911469A EP0638083B1 (en) 1992-04-17 1993-04-16 Method for the preparation and purification of phospholipid mixtures free from contamination by unconventional viruses
AT93911469T ATE150025T1 (de) 1992-04-17 1993-04-16 Verfahren zur herstellung und reinigung von phospholipidmischungen frei von kontaminierenden unkonventionellen viren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD920073A IT1260149B (it) 1992-04-17 1992-04-17 Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali

Publications (3)

Publication Number Publication Date
ITPD920073A0 ITPD920073A0 (it) 1992-04-17
ITPD920073A1 ITPD920073A1 (it) 1993-10-17
IT1260149B true IT1260149B (it) 1996-03-28

Family

ID=11389905

Family Applications (1)

Application Number Title Priority Date Filing Date
ITPD920073A IT1260149B (it) 1992-04-17 1992-04-17 Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali

Country Status (5)

Country Link
EP (1) EP0638083B1 (it)
AT (1) ATE150025T1 (it)
DE (1) DE69308834D1 (it)
IT (1) IT1260149B (it)
WO (1) WO1993021190A1 (it)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2714574B1 (fr) * 1993-12-31 1996-03-15 Inst Rech Biolog Sa Nouveaux suppléments alimentaires pour la nutrition des très jeunes enfants.
FR2721516B1 (fr) * 1994-06-27 1996-09-13 Inst Rech Biolog Sa Nouvelles utilisations d'un complexe à base de phospholipides cérébraux en thérapeutique et dans l'alimentation.
FR2736265B1 (fr) * 1995-07-07 1997-09-26 Forgeot Marcel Nouvelles compositions a base de phosphoglycero ethers et leur utilisation dans le traitement des maladies neuro-degeneratives
FR2750887B1 (fr) * 1996-07-09 1998-10-23 Imedex Procede d'elimination des agents transmissibles non conventionnels (atnc) d'une solution proteique
NZ332323A (en) * 1996-03-15 1999-05-28 Pasteur Merieux Serums Vacc Chromatographic method for removing unconventional transmissible agents from a protein solution
FR2746030B1 (fr) * 1996-03-15 1998-04-17 Procede pour eliminer les agents transmissibles non conventionnels (atnc) d'une solution d'albumine
DE10250727B4 (de) * 2002-04-19 2008-07-10 Cargill, Incorporated, Wayzata Matrix mit einer bioaktiven Phospholipid-haltigen Komponente
EP1503742A2 (de) * 2002-04-19 2005-02-09 Bioghurt Biogarde GmbH & Co. KG. Matrix mit einer bioaktiven phospholipid-haltigen komponente
ITPD20050164A1 (it) * 2005-05-30 2006-11-30 Fidia Farmaceutici Processo per la preparazione e l'isolamento di fosfatidi
IT202100032252A1 (it) 2021-12-22 2023-06-22 Fidia Farm Spa Processo di estrazione e purificazione industriale di fosfolipidi
CN114989212A (zh) * 2022-05-27 2022-09-02 广州白云山汉方现代药业有限公司 一种天然鞘磷脂的制备方法
CN115010748B (zh) * 2022-05-27 2023-10-20 扬州大学 硅胶柱层析同时分离纯化磷脂酰胆碱和鞘磷脂的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1212900B (it) * 1983-11-17 1989-11-30 Valle Francesco Della Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna
ES8506323A1 (es) * 1984-01-04 1985-07-01 Bioiberica Procedimiento para la obtencion de un complejo glicoesfingolipidico
IN171530B (it) * 1989-11-17 1992-11-07 Fidia Spa

Also Published As

Publication number Publication date
EP0638083B1 (en) 1997-03-12
ITPD920073A1 (it) 1993-10-17
ITPD920073A0 (it) 1992-04-17
WO1993021190A1 (en) 1993-10-28
ATE150025T1 (de) 1997-03-15
DE69308834D1 (de) 1997-04-17
EP0638083A1 (en) 1995-02-15

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970131