IT8349355A0 - Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna - Google Patents
Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguignaInfo
- Publication number
- IT8349355A0 IT8349355A0 IT8349355A IT4935583A IT8349355A0 IT 8349355 A0 IT8349355 A0 IT 8349355A0 IT 8349355 A IT8349355 A IT 8349355A IT 4935583 A IT4935583 A IT 4935583A IT 8349355 A0 IT8349355 A0 IT 8349355A0
- Authority
- IT
- Italy
- Prior art keywords
- phosphatidylserine
- effects
- nervous system
- central nervous
- therapeutic use
- Prior art date
Links
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 title 1
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 title 1
- 230000023555 blood coagulation Effects 0.000 title 1
- 208000015114 central nervous system disease Diseases 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J7/00—Phosphatide compositions for foodstuffs, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heat Treatment Of Steel (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Epoxy Resins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT49355/83A IT1212900B (it) | 1983-11-17 | 1983-11-17 | Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna |
US06/599,341 US4595680A (en) | 1983-11-17 | 1984-04-12 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
IE278584A IE58130B1 (en) | 1983-11-17 | 1984-10-30 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
DK524884A DK168271B1 (da) | 1983-11-17 | 1984-11-02 | Farmaceutiske præparater indeholdende phosphatidylserin og fremgangsmåde til fremstilling deraf |
NZ210091A NZ210091A (en) | 1983-11-17 | 1984-11-02 | Phosphatidylserine compositions and their preparation |
IN767/CAL/84A IN162717B (it) | 1983-11-17 | 1984-11-02 | |
IL73420A IL73420A (en) | 1983-11-17 | 1984-11-05 | Phosphatidylserine and phosphatidylethanol amine compositions for treating central nervous system disorders |
ZA848776A ZA848776B (en) | 1983-11-17 | 1984-11-09 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
ES537575A ES8608528A1 (es) | 1983-11-17 | 1984-11-12 | Procedimiento para la fabricacion de fosfatidilserina para el tratamiento de desordenes del sistema nervioso central |
LU85639A LU85639A1 (fr) | 1983-11-17 | 1984-11-13 | Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang |
FR8417262A FR2555050B1 (fr) | 1983-11-17 | 1984-11-13 | Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine, utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang |
FI844468A FI79946C (fi) | 1983-11-17 | 1984-11-14 | Foerfarande foer framstaellning av fosfolipid-sammansaettning anvaendbara vid behandling av sjukdomar i det centrala nervsystemet. |
GR80951A GR80951B (en) | 1983-11-17 | 1984-11-15 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
CH5471/84A CH661734A5 (fr) | 1983-11-17 | 1984-11-15 | Procede de preparation de compositions de phospholipides utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang. |
JP59242174A JPH0676334B2 (ja) | 1983-11-17 | 1984-11-15 | ホスファチジルセリン医薬組成物 |
MX203403A MX160792A (es) | 1983-11-17 | 1984-11-15 | Metodo mejorado para la preparacion de una composicion de fosfolipidos |
DE8484402340T DE3472406D1 (en) | 1983-11-17 | 1984-11-16 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
AU35630/84A AU572228B2 (en) | 1983-11-17 | 1984-11-16 | Phosphatidyl serine compositions for cns disorders |
HU844269A HU193302B (en) | 1983-11-17 | 1984-11-16 | Process for producing phospholipide compositions and pharmaceutical compositions containing them as active agents |
AT84402340T ATE35415T1 (de) | 1983-11-17 | 1984-11-16 | Pharmazeutische zusammensetzungen und verfahren fuer die herstellung von zusammensetzungen mit gehalt an phosphatidylserine zur behandlung von stoerungen des centralen nervensystems ohne wirkungen auf die blutkoagulation. |
PT79510A PT79510B (en) | 1983-11-17 | 1984-11-16 | Phosphatidylserine compositions |
NO844585A NO164275C (no) | 1983-11-17 | 1984-11-16 | Fremgangsmaate for fremstilling av et fosfolipid-preparat. |
EP84402340A EP0148045B1 (en) | 1983-11-17 | 1984-11-16 | Pharmaceutical compositions and method for preparing phosphatidylserine compositions useful in treating central nervous system disorders without effects on blood coagulation |
BE0/214020A BE901074A (nl) | 1983-11-17 | 1984-11-16 | Compositions pharmaceutiques et procede de preparation de compositions de phosphatidylserine utilisables au traitement de desordres du systeme nerveux central sans exercer d'effets sur la coagulation du sang. |
KR1019840007230A KR870001330B1 (ko) | 1983-11-17 | 1984-11-17 | 포스포리피드 조성물의 제조방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT49355/83A IT1212900B (it) | 1983-11-17 | 1983-11-17 | Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8349355A0 true IT8349355A0 (it) | 1983-11-17 |
IT1212900B IT1212900B (it) | 1989-11-30 |
Family
ID=11270453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT49355/83A IT1212900B (it) | 1983-11-17 | 1983-11-17 | Uso terapeutico della fosfatidilserina in malattie del sistema nervoso centrale senza effetti sulla coagulazione sanguigna |
Country Status (25)
Country | Link |
---|---|
US (1) | US4595680A (it) |
EP (1) | EP0148045B1 (it) |
JP (1) | JPH0676334B2 (it) |
KR (1) | KR870001330B1 (it) |
AT (1) | ATE35415T1 (it) |
AU (1) | AU572228B2 (it) |
BE (1) | BE901074A (it) |
CH (1) | CH661734A5 (it) |
DE (1) | DE3472406D1 (it) |
DK (1) | DK168271B1 (it) |
ES (1) | ES8608528A1 (it) |
FI (1) | FI79946C (it) |
FR (1) | FR2555050B1 (it) |
GR (1) | GR80951B (it) |
HU (1) | HU193302B (it) |
IE (1) | IE58130B1 (it) |
IL (1) | IL73420A (it) |
IN (1) | IN162717B (it) |
IT (1) | IT1212900B (it) |
LU (1) | LU85639A1 (it) |
MX (1) | MX160792A (it) |
NO (1) | NO164275C (it) |
NZ (1) | NZ210091A (it) |
PT (1) | PT79510B (it) |
ZA (1) | ZA848776B (it) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2471776A1 (fr) * | 1979-12-21 | 1981-06-26 | Oreal | Nouveaux agents cosmetiques a base de polymeres cationiques, compositions cosmetiques les contenant, et leur application |
IT1213034B (it) * | 1986-02-12 | 1989-12-07 | Istituto Chemioterapico Di Lod | Composizioni farmaceutiche per la terapia di cerebropatie su base organica e funzionale. |
US5314695A (en) * | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
FR2673512B1 (fr) * | 1991-03-05 | 1993-08-20 | Inst Rech Biolog Sa | Nouvelles compositions dietetiques a base de lipides complexes phosphores et leur utilisation dans les troubles du sommeil. |
IT1247165B (it) * | 1991-03-15 | 1994-12-12 | Fidia Spa | Uso terapeutico della fosfatidilserina e derivati in patologie degenerative anche associate a disfunsioni immunitarie. |
IT1248012B (it) * | 1991-06-07 | 1995-01-05 | Mediolanum Farmaceutici Spa | Impiego del fosfatidilinositolo per la terapia dei disturbi della depressione. |
IT1260149B (it) * | 1992-04-17 | 1996-03-28 | Fidia Spa | Metodo per la preparazione e purificazione di miscele di fosfolipidi prive di contaminanti da virus non convenzionali |
GB9621293D0 (en) * | 1996-10-11 | 1996-11-27 | Scotia Holdings Plc | Formulations containing unsaturated fatty acids |
AU2136501A (en) * | 1999-12-10 | 2001-06-18 | Celator Technologies Inc. | Lipid carrier compositions with protected surface reactive functions |
US7226916B1 (en) * | 2000-05-08 | 2007-06-05 | N.V. Nutricia | Preparation for the prevention and/or treatment of vascular disorders |
CA2319928A1 (en) * | 2000-09-18 | 2002-03-18 | Vasogen Ireland Limited | Apoptosis-mimicking synthetic entities and use thereof in medical treatments |
TWI281407B (en) * | 2000-09-18 | 2007-05-21 | Vasogen Ireland Ltd | Apoptosis-mimicking synthetic entities and use thereof in medical treatment |
US6676963B1 (en) * | 2000-10-27 | 2004-01-13 | Barnes-Jewish Hospital | Ligand-targeted emulsions carrying bioactive agents |
CN1625406A (zh) * | 2001-08-09 | 2005-06-08 | 底古萨食品配料有限公司 | 用于预防和治疗温血动物的应激状态的含有溶血磷脂酰丝氨酸的制剂 |
JP4599604B2 (ja) * | 2002-04-19 | 2010-12-15 | カーギル テクスチュアライジング ソリューションズ ドイチュラント ゲゼルシャフト ミット ベシュレクテル ハフツング ウント コンパニー コマンディートゲゼルシャフト | 生体活性のリン脂質含有成分を含有するマトリックス |
US6878532B1 (en) | 2003-04-28 | 2005-04-12 | Sioux Biochemical, Inc. | Method of producing phosphatidylserine |
CN1308334C (zh) * | 2004-06-01 | 2007-04-04 | 山东师范大学 | 一种从动物脑提取磷脂酰丝氨酸的方法 |
IL182372A0 (en) * | 2007-04-01 | 2008-01-20 | Enzymotec Ltd | Compositions containing phosphatidylserine in treating diabetes-associated conditions |
ITMI20121784A1 (it) * | 2012-10-22 | 2014-04-23 | Velleja Res Srl | Composizioni galattogeniche a base di fosfatidilserina |
US20160317560A1 (en) * | 2013-11-07 | 2016-11-03 | The University Of North Carolina At Chapel Hill | Particles containing phospholipids or bioactive fatty acids and uses thereof |
IT202100032252A1 (it) * | 2021-12-22 | 2023-06-22 | Fidia Farm Spa | Processo di estrazione e purificazione industriale di fosfolipidi |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3156616A (en) * | 1958-11-14 | 1964-11-10 | Canada Majesty In Right Of | Composition and method for correcting foods and blood conditions having clot promoting characteristics |
US3436413A (en) * | 1965-12-21 | 1969-04-01 | Canada Packers Ltd | Process for the isolation of phosphatidyl serine |
FR5060M (it) * | 1965-12-22 | 1967-05-08 | ||
US4078052A (en) * | 1976-06-30 | 1978-03-07 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Large unilamellar vesicles (LUV) and method of preparing same |
JPS55115824A (en) * | 1979-02-28 | 1980-09-06 | Nippon Shoji Kk | Remedy for clouding of consciousness and sensomobile disorder |
-
1983
- 1983-11-17 IT IT49355/83A patent/IT1212900B/it active
-
1984
- 1984-04-12 US US06/599,341 patent/US4595680A/en not_active Expired - Fee Related
- 1984-10-30 IE IE278584A patent/IE58130B1/en not_active IP Right Cessation
- 1984-11-02 IN IN767/CAL/84A patent/IN162717B/en unknown
- 1984-11-02 DK DK524884A patent/DK168271B1/da not_active IP Right Cessation
- 1984-11-02 NZ NZ210091A patent/NZ210091A/xx unknown
- 1984-11-05 IL IL73420A patent/IL73420A/xx not_active IP Right Cessation
- 1984-11-09 ZA ZA848776A patent/ZA848776B/xx unknown
- 1984-11-12 ES ES537575A patent/ES8608528A1/es not_active Expired
- 1984-11-13 FR FR8417262A patent/FR2555050B1/fr not_active Expired
- 1984-11-13 LU LU85639A patent/LU85639A1/fr unknown
- 1984-11-14 FI FI844468A patent/FI79946C/fi not_active IP Right Cessation
- 1984-11-15 CH CH5471/84A patent/CH661734A5/fr not_active IP Right Cessation
- 1984-11-15 MX MX203403A patent/MX160792A/es unknown
- 1984-11-15 JP JP59242174A patent/JPH0676334B2/ja not_active Expired - Lifetime
- 1984-11-15 GR GR80951A patent/GR80951B/el unknown
- 1984-11-16 PT PT79510A patent/PT79510B/pt not_active IP Right Cessation
- 1984-11-16 EP EP84402340A patent/EP0148045B1/en not_active Expired
- 1984-11-16 BE BE0/214020A patent/BE901074A/nl not_active IP Right Cessation
- 1984-11-16 HU HU844269A patent/HU193302B/hu not_active IP Right Cessation
- 1984-11-16 DE DE8484402340T patent/DE3472406D1/de not_active Expired
- 1984-11-16 AT AT84402340T patent/ATE35415T1/de not_active IP Right Cessation
- 1984-11-16 NO NO844585A patent/NO164275C/no unknown
- 1984-11-16 AU AU35630/84A patent/AU572228B2/en not_active Ceased
- 1984-11-17 KR KR1019840007230A patent/KR870001330B1/ko not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19950925 |