ES8707248A1 - Un procedimiento para preparar una mezcla de las sales monosodica y disodica de fosfomicina - Google Patents

Un procedimiento para preparar una mezcla de las sales monosodica y disodica de fosfomicina

Info

Publication number
ES8707248A1
ES8707248A1 ES555091A ES555091A ES8707248A1 ES 8707248 A1 ES8707248 A1 ES 8707248A1 ES 555091 A ES555091 A ES 555091A ES 555091 A ES555091 A ES 555091A ES 8707248 A1 ES8707248 A1 ES 8707248A1
Authority
ES
Spain
Prior art keywords
fosfomycin
mono
mixtures
disodium salts
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555091A
Other languages
English (en)
Other versions
ES555091A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia Antibioticos Farma SA
Original Assignee
Pharmacia Antibioticos Farma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Antibioticos Farma SA filed Critical Pharmacia Antibioticos Farma SA
Publication of ES555091A0 publication Critical patent/ES555091A0/es
Publication of ES8707248A1 publication Critical patent/ES8707248A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR SALES MONOSODICA Y DISODICA DE FOSFOMICINA. COMPRENDE: A) HACER REACCIONAR A LA SAL DE FENITILAMINA DE FOSFOMICINA CON METOXIDO SODICO, EN UN MEDIO ALCOHOLICO; Y B) TRATAR A LA MEZCLA DE REACCION DE A) CON ETER DE PETROLEO O ACETONA, PARA PRECIPITAR LAS SALES DE FOSFOMICINA. SE UTILIZAN PARA TRATAR LAS INFECCIONES HUMANAS DE LAS BACTERIAS GRAM-(B) Y GRAM-(C).
ES555091A 1985-09-03 1986-05-19 Un procedimiento para preparar una mezcla de las sales monosodica y disodica de fosfomicina Expired ES8707248A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08521832A GB2179944A (en) 1985-09-03 1985-09-03 Mixtures of mono- and disodium salts of fosfomycin

Publications (2)

Publication Number Publication Date
ES555091A0 ES555091A0 (es) 1987-07-16
ES8707248A1 true ES8707248A1 (es) 1987-07-16

Family

ID=10584632

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555091A Expired ES8707248A1 (es) 1985-09-03 1986-05-19 Un procedimiento para preparar una mezcla de las sales monosodica y disodica de fosfomicina

Country Status (6)

Country Link
EP (1) EP0213704A3 (es)
JP (1) JPS6256498A (es)
AU (1) AU6075686A (es)
ES (1) ES8707248A1 (es)
GB (1) GB2179944A (es)
PT (1) PT83021B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA021876B1 (ru) * 2010-09-20 2015-09-30 ЛИМОНОВ, Виктор Львович Фармацевтическая композиция антимикробного и противовоспалительного действия для парентерального введения, способ ее получения
CA2939604A1 (en) * 2013-11-11 2015-05-14 Forest Laboratories Holdings Limited Compositions and methods of treatment comprising fosfomycin disodium
EP3812007A1 (en) 2019-10-24 2021-04-28 Sandoz Ag New formulations of fosfomycin with reduced sodium content for parenteral use and methods of producing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496080A (en) * 1968-05-15 1970-02-17 Merck & Co Inc Photochemical method for preparing a salt or ester of (cis-1,2-epoxypropyl) phosphonic acid
SE362434B (es) * 1968-05-15 1973-12-10 Merck & Co Inc
IL32155A0 (en) * 1968-05-15 1969-07-30 Merck & Co Inc Synthesis of epoxyphosphonates
US3914231A (en) * 1970-09-04 1975-10-21 Merck & Co Inc ({31 )(Cis-1,2-epoxypropyl)-phosphonic acid and salts thereof

Also Published As

Publication number Publication date
ES555091A0 (es) 1987-07-16
EP0213704A2 (en) 1987-03-11
EP0213704A3 (en) 1987-09-16
PT83021B (en) 1987-12-04
GB2179944A (en) 1987-03-18
GB8521832D0 (en) 1985-10-09
AU6075686A (en) 1987-03-05
PT83021A (en) 1986-08-01
JPS6256498A (ja) 1987-03-12

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