IT1193575B - Procedimento di sintesi di etere fluorometilesafluoroisopropilico - Google Patents

Procedimento di sintesi di etere fluorometilesafluoroisopropilico

Info

Publication number
IT1193575B
IT1193575B IT26992/80A IT2699280A IT1193575B IT 1193575 B IT1193575 B IT 1193575B IT 26992/80 A IT26992/80 A IT 26992/80A IT 2699280 A IT2699280 A IT 2699280A IT 1193575 B IT1193575 B IT 1193575B
Authority
IT
Italy
Prior art keywords
eafluoroisopropyl
aer
fluoromethyl
synthesis process
synthesis
Prior art date
Application number
IT26992/80A
Other languages
English (en)
Other versions
IT8026992A0 (it
Inventor
Clifford L Coon
Robert L Simon
Original Assignee
Baxter Travenol Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Travenol Lab filed Critical Baxter Travenol Lab
Publication of IT8026992A0 publication Critical patent/IT8026992A0/it
Application granted granted Critical
Publication of IT1193575B publication Critical patent/IT1193575B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/34—Separation; Purification; Stabilisation; Use of additives
    • C07C41/40—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation
    • C07C41/42—Separation; Purification; Stabilisation; Use of additives by change of physical state, e.g. by crystallisation by distillation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT26992/80A 1979-12-26 1980-12-29 Procedimento di sintesi di etere fluorometilesafluoroisopropilico IT1193575B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/107,117 US4250334A (en) 1979-12-26 1979-12-26 Method of synthesizing fluoromethylhexafluoroisopropyl ether

Publications (2)

Publication Number Publication Date
IT8026992A0 IT8026992A0 (it) 1980-12-29
IT1193575B true IT1193575B (it) 1988-07-08

Family

ID=22314937

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26992/80A IT1193575B (it) 1979-12-26 1980-12-29 Procedimento di sintesi di etere fluorometilesafluoroisopropilico

Country Status (8)

Country Link
US (1) US4250334A (it)
EP (1) EP0042412B1 (it)
JP (1) JPH0134209B2 (it)
BE (1) BE886750A (it)
CA (1) CA1191873A (it)
DE (1) DE3067596D1 (it)
IT (1) IT1193575B (it)
WO (1) WO1981001846A1 (it)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4996371A (en) * 1990-01-16 1991-02-26 Boc, Inc. Method for fluorodecarboxylation
GB9126355D0 (en) * 1991-12-11 1992-02-12 Ici Plc Production of hydrofluorocarbons
US5637776A (en) * 1992-12-10 1997-06-10 Imperial Chemical Industries Plc Production of hydrofluorocarbons
US5391579A (en) * 1993-01-28 1995-02-21 University Of Iowa Research Foundation Deuterated sevoflurane as an inhalational anesthetic
US5492111A (en) * 1993-01-28 1996-02-20 University Of Iowa Research Foundation Method of elimination of volatile degradation products of sevoflurane during anesthesia
US5382704A (en) * 1993-06-30 1995-01-17 E. I. Du Pont De Nemours And Company Fluorinated methyl ethers
JP2786106B2 (ja) * 1994-03-28 1998-08-13 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
JP2786108B2 (ja) * 1994-03-31 1998-08-13 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
JP2865554B2 (ja) * 1994-04-08 1999-03-08 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルのガスクロマトグラフ分析
JP3240043B2 (ja) * 1996-01-23 2001-12-17 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
CN1074759C (zh) * 1996-02-21 2001-11-14 森陶硝子株式会社 氟甲基1,1,1,3,3,3－六氟异丙醚的生产方法
JP3304829B2 (ja) * 1996-10-17 2002-07-22 花王株式会社 含フッ素エーテル化合物の製造法
US5705710A (en) * 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5990176A (en) 1997-01-27 1999-11-23 Abbott Laboratories Fluoroether compositions and methods for inhibiting their degradation in the presence of a Lewis acid
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) * 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
JP4087488B2 (ja) * 1998-03-03 2008-05-21 セントラル硝子株式会社 フルオロメチル−１，１，１，３，３，３−ヘキサフルオロイソプロピルエーテルの精製方法
US6100434A (en) * 1999-03-26 2000-08-08 Abbott Laboratories Method for synthesizing sevoflurane and an intermediate thereof
US6469219B1 (en) * 2000-03-16 2002-10-22 Halocarbon Products Corporation Production of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
US6245949B1 (en) 2000-06-01 2001-06-12 Abbott Laboratories Synthetic method for the fluoromethylation of alcohols
US6303831B1 (en) 2000-06-01 2001-10-16 Abbott Laboratories Synthetic method for fluoromethylation of halogenated alcohols
US6271422B1 (en) 2000-06-01 2001-08-07 Abbott Laboratories Method for fluoromethylation of alcohols via halogenative decarboxylation
TW523409B (en) 2000-09-15 2003-03-11 Baxter Int Container for inhalation anesthetic
GB0031310D0 (en) * 2000-12-21 2001-01-31 Ici Plc Process for the purification of fluoromethyl hexafluoroisopropyl ether
GB0031301D0 (en) * 2000-12-21 2001-01-31 Ici Plc Process for the production of fluoromethyl hexafluoroisopropyl ether
JP4861161B2 (ja) * 2003-01-14 2012-01-25 バクスター・インターナショナル・インコーポレイテッド セボフルラン合成の廃棄物の流れから１，１，１，３，３，３−ヘキサフルオロイソプロパノールの回収のためのプロセス
CA2605246C (en) * 2005-04-18 2015-11-17 Minrad Inc. Preparation of sevoflurane with negligible water content
CN101263102B (zh) * 2005-08-04 2011-08-17 碳卤化合物产品公司 氟甲基1,1,1,3,3,3-六氟异丙基醚（七氟烷）的纯化
CN1733675A (zh) * 2005-08-26 2006-02-15 山东新时代药业有限公司 一氟代甲基醚的制备方法
JP5315609B2 (ja) 2006-06-05 2013-10-16 ダイキン工業株式会社 新規カルボン酸化合物、その用途及びその製造方法
JP5114880B2 (ja) * 2006-07-06 2013-01-09 ダイキン工業株式会社 新規α−フルオロメトキシカルボン酸エステル、該α−フルオロメトキシカルボン酸エステルの製造方法及びセボフルランの製造方法
MX2009003356A (es) * 2006-09-29 2009-04-14 Cristalia Prod Quimicos Farm Proceso para la preparacion de clorometil 2,2,2-trifluoro-1-(trifl uorometil) etil eter.
JP5163064B2 (ja) * 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
US7732647B2 (en) 2007-12-27 2010-06-08 Halocarbon Products Corporation Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
US20090275785A1 (en) * 2008-05-01 2009-11-05 Barry Jones Distillation Method For The Purification Of Sevoflurane And The Maintenance Of Certain Equipment That May Be Used In The Distillation Process
CN101314560B (zh) * 2008-07-02 2011-06-15 鲁南制药集团股份有限公司 七氟烷的合成方法
CN101659603B (zh) 2008-08-27 2014-05-07 中化蓝天集团有限公司 一种制备氟甲基-1,1,1,3,3,3-六氟异丙基醚的方法
JP5434236B2 (ja) 2009-04-28 2014-03-05 セントラル硝子株式会社 フルオロメチルヘキサフルオロイソプロピルエーテルの製造方法
US9278048B2 (en) * 2009-05-06 2016-03-08 Baxter International, Inc. Pharmaceutical product and method of use
KR20120050474A (ko) 2009-08-10 2012-05-18 솔베이 플루오르 게엠베하 세보플루란의 제조 방법
US9102604B1 (en) 2010-02-15 2015-08-11 Baxter International Inc. Methods for cleaning distilling columns
US8729313B2 (en) 2011-08-15 2014-05-20 Baxter International Inc. Process for the manufacturing of sevoflurane
CN103934020B (zh) * 2013-01-22 2016-03-30 福建海西联合药业有限公司 八取代的双胍盐作为氟甲基六氟异丙基醚的合成催化剂的应用及催化合成方法
DE202017007559U1 (de) 2016-02-23 2022-09-06 Sagetech Medical Equipment Limited Verbesserungen an der Herstellung und Wiederaufbereitung von flüchtigen Narkosewirkstoffen unter Verwendung von überkritischen Fluiden
JP2018075346A (ja) * 2016-11-02 2018-05-17 セントラル硝子株式会社 セボフルラン貯蔵容器の洗浄方法およびセボフルランの貯蔵方法
CA2952552C (en) * 2016-11-02 2018-05-15 Central Glass Company, Limited Method for washing sevoflurane storage container and method for storing sevoflurane
JP6237862B1 (ja) 2016-11-16 2017-11-29 セントラル硝子株式会社 ヘキサフルオロイソプロパノール及び、フルオロメチル ヘキサフルオロイソプロピルエーテル（セボフルラン）の製造方法
JP6299905B1 (ja) 2017-02-06 2018-03-28 セントラル硝子株式会社 セボフルランの製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2992276A (en) * 1959-05-20 1961-07-11 Du Pont Process for preparing polyfluoro alkyl compounds
US3689571A (en) * 1970-07-31 1972-09-05 Baxter Laboratories Inc Fluorinated ether
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia

Also Published As

Publication number Publication date
WO1981001846A1 (en) 1981-07-09
DE3067596D1 (en) 1984-05-24
JPS56501806A (it) 1981-12-10
EP0042412A1 (en) 1981-12-30
EP0042412B1 (en) 1984-04-18
JPH0134209B2 (it) 1989-07-18
CA1191873A (en) 1985-08-13
IT8026992A0 (it) 1980-12-29
EP0042412A4 (en) 1982-04-29
BE886750A (fr) 1981-04-16
US4250334A (en) 1981-02-10

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