IT1167289B - Procedimento per preparare l-carnitina e intermedi chimici impiegati in tale procedimento - Google Patents

Procedimento per preparare l-carnitina e intermedi chimici impiegati in tale procedimento

Info

Publication number
IT1167289B
IT1167289B IT8324018A IT2401883A IT1167289B IT 1167289 B IT1167289 B IT 1167289B IT 8324018 A IT8324018 A IT 8324018A IT 2401883 A IT2401883 A IT 2401883A IT 1167289 B IT1167289 B IT 1167289B
Authority
IT
Italy
Prior art keywords
procedure
carnitine
preparing
intermediates used
chemical intermediates
Prior art date
Application number
IT8324018A
Other languages
English (en)
Italian (it)
Other versions
IT8324018A0 (it
Inventor
Charles H Sih
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/447,171 external-priority patent/US4642290A/en
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IT8324018A0 publication Critical patent/IT8324018A0/it
Application granted granted Critical
Publication of IT1167289B publication Critical patent/IT1167289B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8324018A 1982-12-06 1983-12-05 Procedimento per preparare l-carnitina e intermedi chimici impiegati in tale procedimento IT1167289B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/447,171 US4642290A (en) 1982-12-06 1982-12-06 Process for preparing a compound for use in the production of L-carnitine
US54495783A 1983-10-24 1983-10-24

Publications (2)

Publication Number Publication Date
IT8324018A0 IT8324018A0 (it) 1983-12-05
IT1167289B true IT1167289B (it) 1987-05-13

Family

ID=27034888

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8324018A IT1167289B (it) 1982-12-06 1983-12-05 Procedimento per preparare l-carnitina e intermedi chimici impiegati in tale procedimento

Country Status (23)

Country Link
JP (1) JPH0767674A ( )
KR (1) KR840008165A ( )
AT (1) AT393136B ( )
AU (1) AU566906B2 ( )
CA (1) CA1225956A ( )
CH (1) CH661498A5 ( )
DE (1) DE3344085C2 ( )
DK (1) DK163917C ( )
ES (1) ES8601305A1 ( )
FI (1) FI81115C ( )
FR (1) FR2537130B1 ( )
GB (1) GB2132614B ( )
GR (1) GR78767B ( )
IE (1) IE56322B1 ( )
IL (1) IL70352A ( )
IT (1) IT1167289B ( )
LU (1) LU85115A1 ( )
NL (1) NL8304190A ( )
NO (1) NO159291C ( )
PH (1) PH20456A ( )
PT (1) PT77780B ( )
SE (1) SE455501B ( )
TR (1) TR23136A ( )

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0144832A3 (de) * 1983-12-06 1987-01-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung optisch aktiver, alpha-substituierter 3-Hydroxypropionsäurederivate
IT1181908B (it) * 1984-07-12 1987-09-30 Debi Derivati Biologici Procedimento per la preparazione di l-carnitina
IT1181812B (it) * 1984-07-27 1987-09-30 Sigma Tau Ind Farmaceuti Procedimento per la preparazione dell'acido gamma-dimetilammino l-beta-idrossibutirrico
IT1190358B (it) * 1985-05-24 1988-02-16 Sclavo Spa Procedimento per la preparazione di l-carnitina
JPS62126997A (ja) * 1985-11-28 1987-06-09 Nippon Synthetic Chem Ind Co Ltd:The 光学活性のγ−ハロ−βヒドロキシ酪酸エステルの製造法
IT1189070B (it) * 1986-03-14 1988-01-28 Donegani Guido Ist Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici
JPH0678277B2 (ja) * 1988-02-19 1994-10-05 高砂香料工業株式会社 光学活性アルコールおよびその誘導体の製造方法
JP2939646B2 (ja) * 1990-07-17 1999-08-25 チッソ株式会社 ４―置換―２―ヒドロキシブタン酸エステルおよび製造法
US5215919A (en) * 1991-02-25 1993-06-01 Takeda Chemical Industries, Ltd. Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase
US5324662A (en) 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
JP3155107B2 (ja) * 1993-01-12 2001-04-09 ダイセル化学工業株式会社 光学活性４−ハロ−３−ヒドロキシ酪酸エステルの製造方法
JP2000189170A (ja) * 1998-05-08 2000-07-11 Daicel Chem Ind Ltd 光学活性４―ハロ―３―ヒドロキシ酪酸エステルの製造方法
JP3803551B2 (ja) 1998-08-05 2006-08-02 株式会社カネカ 光学活性２−［６−（ヒドロキシメチル）−１，３−ジオキサン−４−イル］酢酸誘導体の製造法
ATE501264T1 (de) * 2002-08-09 2011-03-15 Codexis Inc Enzymatische verfahren zur herstellung 4- substituierter 3-hydroxybuttersäure-derivate
DE10315760A1 (de) * 2003-04-07 2004-10-21 Basf Ag L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931410A (en) * 1974-02-28 1976-01-06 The Upjohn Company Composition and method of use
CH589604A5 ( ) * 1974-04-26 1977-07-15 Lonza Ag
JPS5139634A (en) * 1974-09-27 1976-04-02 Ono Pharmaceutical Co Ganma amino beeta hidorokishibutansananirido no seizoho
JPS6017776B2 (ja) * 1979-11-07 1985-05-07 電気化学工業株式会社 γ−クロロ−β−ヒドロキシ酪酸アルキルエステルの製法
JPS5950661B2 (ja) * 1980-07-28 1984-12-10 電気化学工業株式会社 γ−アミノ−β−ヒドロキシ酪酸の製造法
JPS5950663B2 (ja) * 1981-04-28 1984-12-10 電気化学工業株式会社 γ−アミノ−β−ヒドロキシ酪酸の製造法

Also Published As

Publication number Publication date
IL70352A0 (en) 1984-02-29
KR840008165A (ko) 1984-12-13
FR2537130B1 (fr) 1988-10-14
NO159291B (no) 1988-09-05
DE3344085C2 (de) 1993-10-14
FI81115B (fi) 1990-05-31
LU85115A1 (fr) 1984-04-02
SE8306714L (sv) 1984-06-07
PH20456A (en) 1987-01-14
ES527807A0 (es) 1985-11-01
TR23136A (tr) 1989-04-11
ATA423783A (de) 1991-01-15
NL8304190A (nl) 1984-07-02
DE3344085A1 (de) 1984-06-07
CH661498A5 (it) 1987-07-31
DK559283A (da) 1984-06-07
FI834419A (fi) 1984-06-07
NO159291C (no) 1988-12-14
IE832732L (en) 1984-06-06
GB2132614B (en) 1986-03-26
FI81115C (fi) 1990-09-10
DK163917B (da) 1992-04-21
GR78767B ( ) 1984-10-02
IT8324018A0 (it) 1983-12-05
GB2132614A (en) 1984-07-11
AU566906B2 (en) 1987-11-05
ES8601305A1 (es) 1985-11-01
IL70352A (en) 1987-10-20
PT77780A (en) 1984-01-01
DK163917C (da) 1992-09-14
SE455501B (sv) 1988-07-18
DK559283D0 (da) 1983-12-05
NO834461L (no) 1984-06-07
IE56322B1 (en) 1991-06-19
FR2537130A1 (fr) 1984-06-08
JPH0767674A (ja) 1995-03-14
GB8332359D0 (en) 1984-01-11
CA1225956A (en) 1987-08-25
FI834419A0 (fi) 1983-12-02
PT77780B (en) 1986-04-17
AU2175883A (en) 1984-06-14
SE8306714D0 (sv) 1983-12-05
AT393136B (de) 1991-08-26

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931119