IT1139175B - Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata - Google Patents

Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata

Info

Publication number
IT1139175B
IT1139175B IT23988/81A IT2398881A IT1139175B IT 1139175 B IT1139175 B IT 1139175B IT 23988/81 A IT23988/81 A IT 23988/81A IT 2398881 A IT2398881 A IT 2398881A IT 1139175 B IT1139175 B IT 1139175B
Authority
IT
Italy
Prior art keywords
antiandrogen
prophylaxis
therapy
combination
prophylaxy
Prior art date
Application number
IT23988/81A
Other languages
English (en)
Italian (it)
Other versions
IT8123988A0 (it
Inventor
Hans Udo Schweikert
Ulf Tunn
Theodor Senge
Friedmund Neumann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IT8123988A0 publication Critical patent/IT8123988A0/it
Application granted granted Critical
Publication of IT1139175B publication Critical patent/IT1139175B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT23988/81A 1981-05-22 1981-09-16 Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata IT1139175B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813121152 DE3121152A1 (de) 1981-05-22 1981-05-22 "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie"

Publications (2)

Publication Number Publication Date
IT8123988A0 IT8123988A0 (it) 1981-09-16
IT1139175B true IT1139175B (it) 1986-09-24

Family

ID=6133382

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23988/81A IT1139175B (it) 1981-05-22 1981-09-16 Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata

Country Status (15)

Country Link
US (1) US4598072A (cg-RX-API-DMAC7.html)
JP (1) JPS57193412A (cg-RX-API-DMAC7.html)
AU (1) AU563785B2 (cg-RX-API-DMAC7.html)
BE (1) BE890522A (cg-RX-API-DMAC7.html)
CA (1) CA1186998A (cg-RX-API-DMAC7.html)
CH (1) CH648211A5 (cg-RX-API-DMAC7.html)
DE (1) DE3121152A1 (cg-RX-API-DMAC7.html)
DK (1) DK354881A (cg-RX-API-DMAC7.html)
FR (1) FR2506158B1 (cg-RX-API-DMAC7.html)
GB (1) GB2102287B (cg-RX-API-DMAC7.html)
IT (1) IT1139175B (cg-RX-API-DMAC7.html)
LU (1) LU83545A1 (cg-RX-API-DMAC7.html)
NL (1) NL8103875A (cg-RX-API-DMAC7.html)
SE (1) SE463074B (cg-RX-API-DMAC7.html)
ZA (1) ZA823501B (cg-RX-API-DMAC7.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607651A1 (de) * 1986-03-06 1987-09-10 Schering Ag Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5595985A (en) 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
ES2133270T3 (es) * 1989-07-07 1999-09-16 Endorecherche Inc Terapia de combinacion para la profilaxis y/o el tratamiento de hiperplasia prostatica benigna.
JP3350048B2 (ja) * 1989-07-07 2002-11-25 アンドルシェルシュ・インコーポレイテッド アンドロゲン関連疾患の治療方法
DE4001060A1 (de) * 1990-01-16 1991-07-18 Kanoldt Arzneimittel Gmbh Verwendung einer ungesaettigten fettsaeure oder ihrer derivate in der human- und veterinaermedizin und zur herstellung einer arzneimittelzubereitung
TW239145B (cg-RX-API-DMAC7.html) * 1992-05-21 1995-01-21 Endorech Inc
GB2278054A (en) * 1993-05-18 1994-11-23 Zeneca Ltd Compounds for the treatment of urinary incontinence
EP1094798A2 (en) * 1998-03-11 2001-05-02 Endorecherche Inc. INHIBITORS OF TYPE 5 AND TYPE 3 17beta-HYDROXYSTEROID DEHYDROGENASE AND METHODS FOR THEIR USE
DE19825591A1 (de) * 1998-06-09 1999-12-23 Jenapharm Gmbh Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata
GB9930839D0 (en) * 1999-12-30 2000-02-16 Pharmacia & Upjohn Spa Process for treating gynecomastia
GB0012293D0 (en) * 2000-05-23 2000-07-12 Astrazeneca Ab Pharmaceutical combination
US7001911B2 (en) * 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
JP2004509072A (ja) * 2000-06-28 2004-03-25 ブリストル−マイヤーズ　スクイブ　カンパニー 選択的アンドロゲン受容体モジュレーター並びにその同定、設計及び使用方法
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU6800101A (en) * 2000-07-05 2002-01-14 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and anastrozole for providing an antiandrogenic effect and aromatase inhibition
GB0016426D0 (en) * 2000-07-05 2000-08-23 Astrazeneca Ab Pharmaceutical combination
WO2002002113A1 (en) * 2000-07-05 2002-01-10 Astrazeneca Ab Pharmaceutical combination of an anti-androgen and letrozole for providing an anit-androgenic effect and aromatase inhibition
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6607755B2 (en) 2001-06-21 2003-08-19 Michael Donald Farley Anti-aromatase pharmaceutical composition for controlling testosterone/estrone ratios
SE0103839D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Pharmaceutical formulation & product
EP1467979B1 (en) * 2001-12-19 2008-08-13 Bristol-Myers Squibb Company Fused heterocyclic compounds and analogs thereof modulators of nuclear hormone receptor function
WO2004058234A2 (en) 2002-12-27 2004-07-15 Schering Aktiengesellschaft Pharmaceutical combinations of phthalazine vegf inhibitors and benzamide hdac inhibitors
ES2628507T3 (es) * 2007-11-13 2017-08-03 Athenion Ag Esteroides C-19 para el tratamiento de la celulitis
WO2010081817A1 (en) * 2009-01-14 2010-07-22 Boehringer Ingelheim International Gmbh Method for treating colorectal cancer
CN106421792A (zh) 2012-02-06 2017-02-22 创新医学概念有限责任公司 包含抗病毒成分和cox‑2抑制剂成分组合的药物组合物及用于药物组合疗法的药盒
EP2762135A1 (en) * 2013-02-04 2014-08-06 Sanofi Methods for reducing the risk of an adverse teriflunomide and rosuvastatin interaction in multiple sclerosis patients
KR20240157117A (ko) * 2014-04-08 2024-10-31 더 메서디스트 하스피틀 iNOS-억제 조성물들 및 이들의 유방암 치료제로서의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3423507A (en) * 1966-02-25 1969-01-21 Schering Corp Method of treating benign prostratic hypertrophy
US3449494A (en) * 1966-09-29 1969-06-10 Squibb & Sons Inc Anti-inflammatory compositions containing a corticoidal steroid and a testololactone
US4055641A (en) * 1976-05-10 1977-10-25 Richardson-Merrell Inc. Method of treating benign prostatic hypertrophy
DE2817157A1 (de) * 1978-04-17 1979-10-25 Schering Ag Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
EP0100566B1 (en) * 1982-07-14 1986-02-19 Akzo N.V. Novel 19-thio-androstane derivatives

Also Published As

Publication number Publication date
CH648211A5 (de) 1985-03-15
IT8123988A0 (it) 1981-09-16
US4598072A (en) 1986-07-01
LU83545A1 (de) 1981-12-01
SE8104624L (sv) 1982-11-23
ZA823501B (en) 1983-03-30
FR2506158A1 (fr) 1982-11-26
DE3121152C2 (cg-RX-API-DMAC7.html) 1991-02-07
SE463074B (sv) 1990-10-08
AU563785B2 (en) 1987-07-23
CA1186998A (en) 1985-05-14
BE890522A (fr) 1982-03-29
AU8407582A (en) 1982-11-25
GB2102287A (en) 1983-02-02
DE3121152A1 (de) 1982-12-09
NL8103875A (nl) 1982-12-16
JPS57193412A (en) 1982-11-27
FR2506158B1 (fr) 1986-05-09
JPH0150207B2 (cg-RX-API-DMAC7.html) 1989-10-27
DK354881A (da) 1982-11-23
GB2102287B (en) 1985-02-27

Similar Documents

Publication Publication Date Title
IT1139175B (it) Impiego della combinazione di un inibitore della aromatasi con un antiandrogeno per la profilassi e la terapia dell iperplasia della prostata
IT1119733B (it) Impiego di antiestrogeni e antiandrogeni ad azione antigonadotropa per la profilassi e la terapia della iperplasia prostatica
IT8026551A0 (it) Trattamenti e procedimento per inibire la corrosione di metalli.
IT1168028B (it) Impiego di inibitori dell'aromatasi per la profilassi e la terapia della iperplasia della prostata
IT1191235B (it) Procedimento per la preparazione di 3 idrossi ml 236b derivati particolarmente per il trattamento dell iperlipemia e la profilassi dell arteriosclerosi
IT1156538B (it) Composizioni oleose comprendenti un principio attivo dermatologico destinate al trattamento del cuoio capelluto o della pelle
NO177430C (no) Vannavstötningsmiddel og anvendelse av vannavstötningsmidlet som tilsats til gips
DE3576328D1 (de) Behandlung feuerfester gegenstaende.
ATE34077T1 (de) Hautbehandlungsmittel.
UY24036A1 (es) Mejoras en (o relativas a) agentes anti- protozoarios
IT1141070B (it) Impiego dell'alfa-chetoglutarato di piridossina nella profilassi della iperlattacidemia
ATE69953T1 (de) Verwendung von polysulfatierten heparinen.
GR3004521T3 (cg-RX-API-DMAC7.html)
IT8320435A0 (it) Composizione per il trattamento dell'acne.
NO921223D0 (no) Kombinasjonspreparat med antitrombotisk virkning
IT1140088B (it) Bioprotesi valvolare cardiaca e suo procedimento di ottenimento
FI892396A7 (fi) Korroosionkestävän teräksen lämpökäsittely
FI823817A7 (fi) Nitroimidatsoliyhdisteitä ja näppyjen hoidossa käyttökelpoisia seoksia.
IT8421358A0 (it) Derivato della ranitidina utile nel trattamento dell'ulcera.
IT8168240A0 (it) Agente per il miglioramento della circolazione sanguigna periferica
FR2592397A1 (fr) Inhibiteur de corrosion des bains de decapage des surfaces metalliques.
IT8422850A0 (it) Metodi per il trattamento della disritmia ventricolare e per la prevenzione della fibrillazione ventricolare.
IT7968657A0 (it) Composizione per la prevenzione ed il trattamento della coccidiosi nel pollame
SG79394G (en) New use of 1.4-dihydropyridine derivatives.
IT8168143A0 (it) Composto per il trattamento e la prevenzione della diarrea in animali