IT1119733B - Impiego di antiestrogeni e antiandrogeni ad azione antigonadotropa per la profilassi e la terapia della iperplasia prostatica - Google Patents
Impiego di antiestrogeni e antiandrogeni ad azione antigonadotropa per la profilassi e la terapia della iperplasia prostaticaInfo
- Publication number
- IT1119733B IT1119733B IT21854/79A IT2185479A IT1119733B IT 1119733 B IT1119733 B IT 1119733B IT 21854/79 A IT21854/79 A IT 21854/79A IT 2185479 A IT2185479 A IT 2185479A IT 1119733 B IT1119733 B IT 1119733B
- Authority
- IT
- Italy
- Prior art keywords
- antiandrogen
- estrogen
- prophylaxis
- therapy
- prostatic hyperplasia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782817157 DE2817157A1 (de) | 1978-04-17 | 1978-04-17 | Verwendung von antioestrogenen und antigonadotrop wirkenden antiandrogenen zur prophylaxe und therapie der prostatahyperplasie |
Publications (2)
Publication Number | Publication Date |
---|---|
IT7921854A0 IT7921854A0 (it) | 1979-04-13 |
IT1119733B true IT1119733B (it) | 1986-03-10 |
Family
ID=6037493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT21854/79A IT1119733B (it) | 1978-04-17 | 1979-04-13 | Impiego di antiestrogeni e antiandrogeni ad azione antigonadotropa per la profilassi e la terapia della iperplasia prostatica |
Country Status (13)
Country | Link |
---|---|
US (1) | US4310523A (it) |
JP (1) | JPS5513261A (it) |
AU (1) | AU528179B2 (it) |
BE (1) | BE875634A (it) |
CA (1) | CA1134271A (it) |
CH (1) | CH641679A5 (it) |
DE (1) | DE2817157A1 (it) |
GB (1) | GB2018591B (it) |
IT (1) | IT1119733B (it) |
LU (1) | LU81153A1 (it) |
NL (1) | NL7901961A (it) |
SE (1) | SE441977B (it) |
ZA (1) | ZA791797B (it) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3121153A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "verwendung von aromatase-hemmern zur prophylaxe und therapie der prostatahyperplasie" |
DE3121152A1 (de) * | 1981-05-22 | 1982-12-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | "verwendung der kombination eines aromatase-hemmers mit einem antiandrogen zur prophylaxe und therapie der prostatahyperplasie" |
DE3339295A1 (de) * | 1982-11-15 | 1984-05-17 | Schering AG, 1000 Berlin und 4709 Bergkamen | 4-hydroxy- und 4-acyloxy-4-androsten-3,17-dione zur verwendung bei der prophylaxe und therapie der prostatahyperplasie und diese enthaltende mittel fuer derartige verwendung |
WO1985002543A1 (en) * | 1983-12-12 | 1985-06-20 | Kaszynski Edwin G | Hair growth modification |
US4885289A (en) * | 1983-12-12 | 1989-12-05 | Breuer Miklos M | Alteration of character of male beard growth |
DE3607651A1 (de) * | 1986-03-06 | 1987-09-10 | Schering Ag | Kombination von aromatasehemmer und testosteron-5(alpha)-reduktase-hemmer |
US4895715A (en) * | 1988-04-14 | 1990-01-23 | Schering Corporation | Method of treating gynecomastia |
US5116615A (en) * | 1989-01-27 | 1992-05-26 | Immunolytics, Inc. | Method for treating benign prostatic hypertrophy |
ES2072424T3 (es) | 1989-01-27 | 1995-07-16 | Immunolytics Inc | Formula y metodo para el tratamiento de hipertrofias prostaticas benignas. |
US5595985A (en) * | 1989-03-10 | 1997-01-21 | Endorecherche Inc. | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia |
WO1991000731A1 (en) * | 1989-07-07 | 1991-01-24 | Endorecherche Inc. | Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia |
US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6743419B1 (en) | 1992-12-22 | 2004-06-01 | The Gillette Company | Method of reducing hair growth employing sulfhydryl active compounds |
US5411991A (en) * | 1992-12-22 | 1995-05-02 | Shander; Douglas | Method of reducing hair growth employing sulfhydryl active compounds |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
EP0729363B1 (en) * | 1994-06-27 | 2003-02-19 | Neutron Therapies Inc. | Boron-containing hormone analogs and methods of their use in imaging or killing cells having hormone receptors |
US20030083733A1 (en) * | 1997-10-10 | 2003-05-01 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US20020091433A1 (en) * | 1995-04-19 | 2002-07-11 | Ni Ding | Drug release coated stent |
US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
JPH11507050A (ja) * | 1995-06-07 | 1999-06-22 | メルク エンド カンパニー インコーポレーテッド | 前立腺病の処置および予防 |
US5726202A (en) * | 1996-01-11 | 1998-03-10 | Novo Nordisk A/S | Benign prostatic hypertrophy |
AU6959898A (en) * | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
EP1321146A3 (en) * | 1998-03-11 | 2004-06-02 | Endorecherche Inc. | Inhibitors of type 5 and 3 17beta-hydroxysteroid dehydrogenase and methods for their use |
BR9908592A (pt) * | 1998-03-11 | 2001-04-24 | Endorech Inc | Processo para inibir a atividade de 17ß-hidroxiesteróide desidrogenase tipo 5, composição farmacêutica, inibidor de 17ß-hidroxiesteróide desidrogenase tipo 5, processo para inibir 17ß-hidroxiesteróide desidrogenase tipo 3, inibidor de 17ß-hidroxiesteróide desidrogenase tipo 3, processos para tratar, ou reduzir o risco de desenvolver, câncer da próstata, hiperplasia prostática benigna, acne, seborréia, hirsutismo ou alopécia androgênica, sìndrome de ovário policìstico, câncer de mama, endometriose ou leiomioma, para inibir as secreções hormonais testiculares, para tratar puberdade precoce, e, kit |
DE19825591A1 (de) * | 1998-06-09 | 1999-12-23 | Jenapharm Gmbh | Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata |
US20030083231A1 (en) * | 1998-11-24 | 2003-05-01 | Ahlem Clarence N. | Blood cell deficiency treatment method |
CA2372720C (en) | 1999-05-04 | 2007-09-11 | John Antony Kanis | Androgen glycosides and androgenic activity thereof |
EP2322182A1 (en) | 1999-09-30 | 2011-05-18 | Harbor BioSciences, Inc. | Androstenol derivatives as androgen receptor modulator |
US6960474B2 (en) * | 2000-06-28 | 2005-11-01 | Bristol-Myers Squibb Company | Method for the treatment of a condition remediable by administration of a selective androgen receptor modulator |
EP1324754A1 (en) * | 2000-07-05 | 2003-07-09 | AstraZeneca AB | Pharmaceutical combination of an anti-androgen and tamoxifen for providing an anti-androgenic effect and aromatase inhibition |
US6613083B2 (en) * | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
US7332525B2 (en) | 2003-01-17 | 2008-02-19 | Castle Erik P | Method of treatment of prostate cancer and composition for treatment thereof |
ES2665917T3 (es) | 2006-11-21 | 2018-04-30 | Jina Pharmaceuticals Inc. | Endoxifeno para su uso en el tratamiento del cáncer |
US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
CA2739887A1 (en) * | 2008-10-10 | 2010-04-15 | Teva Women's Health, Inc. | Methods for treating vasomotor symptoms in castrated prostatic cancer patients with low dose cyproterone acetate |
US20160361380A1 (en) | 2015-06-12 | 2016-12-15 | Nymox Corporation | Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations |
US10183058B2 (en) | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
US10172910B2 (en) | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3076823A (en) * | 1961-07-03 | 1963-02-05 | Syntex Corp | Process for the production of 6-chloro-3-keto-deta steroid compounds |
US3423507A (en) * | 1966-02-25 | 1969-01-21 | Schering Corp | Method of treating benign prostratic hypertrophy |
US4055641A (en) * | 1976-05-10 | 1977-10-25 | Richardson-Merrell Inc. | Method of treating benign prostatic hypertrophy |
-
1978
- 1978-04-17 DE DE19782817157 patent/DE2817157A1/de not_active Withdrawn
-
1979
- 1979-03-12 NL NL7901961A patent/NL7901961A/xx not_active Application Discontinuation
- 1979-04-02 AU AU45604/79A patent/AU528179B2/en not_active Ceased
- 1979-04-09 GB GB7912416A patent/GB2018591B/en not_active Expired
- 1979-04-11 CH CH346479A patent/CH641679A5/de not_active IP Right Cessation
- 1979-04-11 SE SE7903240A patent/SE441977B/sv not_active IP Right Cessation
- 1979-04-13 LU LU81153A patent/LU81153A1/de unknown
- 1979-04-13 IT IT21854/79A patent/IT1119733B/it active
- 1979-04-17 CA CA325,574A patent/CA1134271A/en not_active Expired
- 1979-04-17 BE BE0/194651A patent/BE875634A/xx not_active IP Right Cessation
- 1979-04-17 JP JP4610479A patent/JPS5513261A/ja active Granted
- 1979-04-17 ZA ZA791797A patent/ZA791797B/xx unknown
-
1980
- 1980-10-10 US US06/195,812 patent/US4310523A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
GB2018591A (en) | 1979-10-24 |
IT7921854A0 (it) | 1979-04-13 |
CH641679A5 (de) | 1984-03-15 |
BE875634A (fr) | 1979-10-17 |
SE441977B (sv) | 1985-11-25 |
US4310523A (en) | 1982-01-12 |
NL7901961A (nl) | 1979-10-19 |
ZA791797B (en) | 1980-11-26 |
JPS645007B2 (it) | 1989-01-27 |
SE7903240L (sv) | 1979-10-18 |
DE2817157A1 (de) | 1979-10-25 |
LU81153A1 (de) | 1979-06-19 |
GB2018591B (en) | 1982-09-08 |
AU4560479A (en) | 1979-10-25 |
CA1134271A (en) | 1982-10-26 |
JPS5513261A (en) | 1980-01-30 |
AU528179B2 (en) | 1983-04-21 |
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