IT1058296B - Preparato cosemtico a base di agenti per la cura della bocca e dei denti che contengono un acido amminoalcaredifosfonico oppure i suoi sali idrosolubili - Google Patents
Preparato cosemtico a base di agenti per la cura della bocca e dei denti che contengono un acido amminoalcaredifosfonico oppure i suoi sali idrosolubiliInfo
- Publication number
- IT1058296B IT1058296B IT19644/75A IT1964475A IT1058296B IT 1058296 B IT1058296 B IT 1058296B IT 19644/75 A IT19644/75 A IT 19644/75A IT 1964475 A IT1964475 A IT 1964475A IT 1058296 B IT1058296 B IT 1058296B
- Authority
- IT
- Italy
- Prior art keywords
- alkared
- care
- mouth
- amino
- agents
- Prior art date
Links
- -1 AMINO Chemical class 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 239000002537 cosmetic Substances 0.000 title 1
- XQRLCLUYWUNEEH-UHFFFAOYSA-N diphosphonic acid Chemical compound OP(=O)OP(O)=O XQRLCLUYWUNEEH-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2405254A DE2405254C2 (de) | 1974-02-04 | 1974-02-04 | Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IT1058296B true IT1058296B (it) | 1982-04-10 |
Family
ID=5906567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT19644/75A IT1058296B (it) | 1974-02-04 | 1975-01-28 | Preparato cosemtico a base di agenti per la cura della bocca e dei denti che contengono un acido amminoalcaredifosfonico oppure i suoi sali idrosolubili |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3962432A (it) |
| JP (1) | JPS50107148A (it) |
| AT (1) | AT332557B (it) |
| BE (1) | BE822930A (it) |
| CA (1) | CA1033666A (it) |
| CH (1) | CH610201A5 (it) |
| DE (1) | DE2405254C2 (it) |
| FR (1) | FR2259615B1 (it) |
| GB (1) | GB1435885A (it) |
| IT (1) | IT1058296B (it) |
| NL (1) | NL176999B (it) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2534391C2 (de) * | 1975-08-01 | 1983-01-13 | Henkel KGaA, 4000 Düsseldorf | 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren |
| DE2553963A1 (de) * | 1975-12-01 | 1977-06-08 | Henkel & Cie Gmbh | Pharmazeutische praeparate zur behandlung von stoerungen des calciumstoffwechsels |
| DE2745083C2 (de) | 1977-10-07 | 1985-05-02 | Henkel KGaA, 4000 Düsseldorf | Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung |
| FR2489334A1 (fr) * | 1980-09-04 | 1982-03-05 | Vysoka Skola Chem Tech | Acide 6-amino-1-hydroxyhexilidene-diphosphonique, ses sels, et procede pour l'obtention de ces produits |
| IT1194748B (it) * | 1981-02-12 | 1988-09-28 | Gentili Ist Spa | Composizioni farmaceutiche per il trattamento di osteopatie |
| DE3313049A1 (de) * | 1982-04-15 | 1983-11-17 | Istituto Gentili S.p.A., 56100 Pisa | Pharmakologisch wirksame biphosphonate, verfahren fuer ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen |
| IT1201087B (it) * | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| US4446052A (en) * | 1982-05-17 | 1984-05-01 | The Procter & Gamble Company | Aqueous gel containing tricalcium di(1-hydroxy-3-aminopropane-1,1-diphosphonate |
| DE3225469A1 (de) * | 1982-07-05 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate |
| GB2162746B (en) * | 1983-12-21 | 1987-07-29 | Inst Org Fiz Khim Arbuzova | Antiacidotic medicinal agent |
| IT1195993B (it) * | 1984-01-12 | 1988-11-03 | Gentili Ist Spa | Forme farmaceutiche a base di difosfonati |
| FR2558837B1 (fr) * | 1984-01-26 | 1986-06-27 | Sanofi Sa | Derives de l'acide methylenediphosphonique, procede d'obtention et medicaments antirhumatismaux les contenant |
| DE3425812A1 (de) * | 1984-07-13 | 1986-01-16 | Deutsches Krebsforschungszentrum, 6900 Heidelberg | Neue 1-hydroxy-1,1-diphosphonsaeureverbindungen, verfahren zu ihrer herstellung und pharmakologische zubereitungen, insbesondere zur behandlung von knochentumoren |
| US4639338A (en) * | 1984-08-06 | 1987-01-27 | Ciba-Geigy Corporation | Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate |
| DE3434667A1 (de) * | 1984-09-21 | 1986-04-03 | Henkel KGaA, 4000 Düsseldorf | 4-dimethylamino-1-hydroxybutan-1,1-diphosphonsaeure, deren wasserloesliche salze, verfahren zu ihrer herstellung sowie ihre verwendung |
| US4575456A (en) * | 1984-11-30 | 1986-03-11 | Colgate-Palmolive Company | Gel dentifrice of desirable consistency |
| IT1187828B (it) * | 1985-05-24 | 1987-12-23 | Gentili Ist Spa | Composizione farmaceutica a base di difosfonati per il trattamento dell aretrosi |
| DE3540150A1 (de) * | 1985-11-13 | 1987-05-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DE3623397A1 (de) * | 1986-07-11 | 1988-01-14 | Boehringer Mannheim Gmbh | Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| DE3724654A1 (de) * | 1987-07-25 | 1989-02-02 | Henkel Kgaa | Hydroxyacetonitrildiphosphonsaeure, verfahren zu ihrer herstellung und ihre verwendung |
| FR2629716B1 (fr) * | 1988-04-07 | 1991-07-19 | Sanofi Sa | Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique |
| MX21453A (es) * | 1989-07-07 | 1994-01-31 | Ciba Geigy Ag | Preparaciones farmaceuticas que se administran en forma topica. |
| US5139786A (en) * | 1989-07-07 | 1992-08-18 | Ciba-Geigy Corporation | Topical formulations |
| MX21452A (es) * | 1989-07-07 | 1994-01-31 | Ciba Geigy Ag | Preparaciones farmaceuticas que se administran en forma topica. |
| US5227506A (en) * | 1989-09-06 | 1993-07-13 | Merck & Co., Inc. | Acyloxymethyl esters of bisphosphonic acids as bone resorption inhibitors |
| US5356887A (en) * | 1990-01-31 | 1994-10-18 | Merck & Co., Inc. | Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids |
| US5270365A (en) * | 1991-12-17 | 1993-12-14 | Merck & Co., Inc. | Prevention and treatment of periodontal disease with alendronate |
| EP0550385A1 (de) * | 1991-12-19 | 1993-07-07 | Ciba-Geigy Ag | Peroral zu verabreichende pharmazeutische Zusammensetzungen, die Methandiphosphonsäure-Derivate und 18-Krone-6 Ether enthalten |
| TW237386B (it) | 1992-04-15 | 1995-01-01 | Ciba Geigy | |
| US6406714B1 (en) | 1992-12-02 | 2002-06-18 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids |
| TW390813B (en) * | 1994-04-29 | 2000-05-21 | Merck & Co Inc | Wet granulation formulation for bisphosphonic acids |
| US20010007863A1 (en) * | 1998-06-18 | 2001-07-12 | Merck & Co., Inc. | Wet granulation formulation for bisphosphonic acids |
| GB9408775D0 (en) * | 1994-05-04 | 1994-06-22 | Ciba Geigy Ag | Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration |
| EP0753523A1 (en) | 1995-07-10 | 1997-01-15 | Gador S.A. | Amino-substituted bisphosphonic acids |
| EP0854724B1 (en) * | 1995-09-29 | 2005-03-16 | Novartis AG | Method of treating the navicular disease in horses |
| US6160165A (en) | 1998-12-10 | 2000-12-12 | Aesgen, Inc. | Method for preparation of disodium pamidronate |
| US6794536B1 (en) | 1998-12-10 | 2004-09-21 | Aesqen, Inc. | Method for preparation of disodium pamidronate |
| DE69907258T2 (de) | 1998-12-10 | 2003-11-06 | Aesgen, Inc. | Verfahren zur herstellung von dinatriumpamidronat |
| AR021347A1 (es) | 1999-10-20 | 2002-07-17 | Cipla Ltd | Una composicion farmaceutica que contiene acido(s) bisfosfoncio o sal(es) del mismo y un proceso de preparacion de la misma |
| US6677320B2 (en) | 2000-01-20 | 2004-01-13 | Hoffmann-La Roches Inc. | Parenteral bisphosphonate composition with improved local tolerance |
| US6638920B2 (en) * | 2000-07-21 | 2003-10-28 | Merck & Co., Inc. | Compositions and methods of preventing or reducing the risk or incidence of skeletal injuries in horses |
| EP1372669B1 (en) * | 2001-01-23 | 2005-06-15 | Gador S.A. | Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof |
| CZ20032951A3 (cs) * | 2001-05-02 | 2004-02-18 | Sicor Inc. | Injikovatelný pamidronate disodium |
| CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| TWI315982B (en) | 2001-07-19 | 2009-10-21 | Novartis Ag | Combinations comprising epothilones and pharmaceutical uses thereof |
| NZ532994A (en) * | 2001-12-21 | 2008-05-30 | Procter & Gamble | Method for the treatment of bone disorders using a bisphosphonate regimen, risedronate in particular |
| BR0308901A (pt) * | 2002-05-10 | 2005-01-04 | Hoffmann La Roche | ácidos bisfosfÈnicos para tratamento e prevenção de osteoporose |
| US20040138180A1 (en) * | 2002-10-03 | 2004-07-15 | Barr Laboratories, Inc. | Bisphosphonate composition and process for the preparation thereof |
| AU2003250218B2 (en) * | 2002-12-20 | 2006-10-26 | F. Hoffmann-La Roche Ag | High dose Ibandronate formulation |
| US20050119230A1 (en) * | 2003-09-18 | 2005-06-02 | Alexandra Glausch | Pharmaceutical products comprising bisphosphonated |
| US20100144679A1 (en) * | 2007-03-21 | 2010-06-10 | Duke University | Medication kits and formulations for preventing, treating or reducing secondary fractures after previous fracture |
| PL2473172T3 (pl) | 2009-09-01 | 2015-08-31 | Univ Duke | Kompozycje bisfosfonianowe i sposoby do leczenia niewydolności serca |
| JP2013525294A (ja) | 2010-04-16 | 2013-06-20 | ノバルティス アーゲー | インプラント骨結合を改善するための方法および組成物 |
| WO2013074587A1 (en) | 2011-11-16 | 2013-05-23 | Duke University | Bishophonate compositions and methods for treating and/or reducing cardiac dysfunction |
| PL407922A1 (pl) | 2014-04-16 | 2015-10-26 | Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością | Nowe bisfosfoniany i ich zastosowanie |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH9776A (en) * | 1967-12-11 | 1976-03-17 | M Francis | Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue and method of use |
| DE2130794C3 (de) * | 1971-06-22 | 1974-07-11 | Joh. A. Benckiser Gmbh, 6700 Ludwigshafen | Verfahren zur Herstellung von l-Hydroxy-S-amino-propan-ljl-diphosphonsäure |
-
1974
- 1974-02-04 DE DE2405254A patent/DE2405254C2/de not_active Expired
- 1974-11-15 NL NLAANVRAGE7414947,A patent/NL176999B/xx not_active Application Discontinuation
- 1974-12-03 US US05/529,039 patent/US3962432A/en not_active Expired - Lifetime
- 1974-12-04 BE BE151140A patent/BE822930A/xx not_active IP Right Cessation
- 1974-12-05 CA CA215,302A patent/CA1033666A/en not_active Expired
- 1974-12-05 GB GB5255874A patent/GB1435885A/en not_active Expired
- 1974-12-06 FR FR7439995A patent/FR2259615B1/fr not_active Expired
-
1975
- 1975-01-28 IT IT19644/75A patent/IT1058296B/it active
- 1975-02-03 AT AT76175*#A patent/AT332557B/de not_active IP Right Cessation
- 1975-02-03 CH CH124375A patent/CH610201A5/xx not_active IP Right Cessation
- 1975-02-03 JP JP50013494A patent/JPS50107148A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3962432A (en) | 1976-06-08 |
| FR2259615B1 (it) | 1978-07-21 |
| JPS50107148A (it) | 1975-08-23 |
| FR2259615A1 (it) | 1975-08-29 |
| BE822930A (fr) | 1975-06-04 |
| NL7414947A (nl) | 1975-08-06 |
| GB1435885A (en) | 1976-05-19 |
| DE2405254A1 (de) | 1975-08-14 |
| DE2405254C2 (de) | 1982-05-27 |
| CH610201A5 (it) | 1979-04-12 |
| ATA76175A (de) | 1976-01-15 |
| CA1033666A (en) | 1978-06-27 |
| NL176999B (nl) | 1985-02-18 |
| AT332557B (de) | 1976-10-11 |
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