IS8282A - Kortlagning genamengja starfrænna DNA þátta og frumuprótína - Google Patents
Kortlagning genamengja starfrænna DNA þátta og frumuprótínaInfo
- Publication number
- IS8282A IS8282A IS8282A IS8282A IS8282A IS 8282 A IS8282 A IS 8282A IS 8282 A IS8282 A IS 8282A IS 8282 A IS8282 A IS 8282A IS 8282 A IS8282 A IS 8282A
- Authority
- IS
- Iceland
- Prior art keywords
- genome
- mapping
- cellular proteins
- dna elements
- functional dna
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48505203P | 2003-07-03 | 2003-07-03 | |
PCT/US2004/021450 WO2005007814A2 (en) | 2003-07-03 | 2004-07-02 | Genome mapping of functional dna elements and cellular proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
IS8282A true IS8282A (is) | 2006-02-01 |
Family
ID=34079090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS8282A IS8282A (is) | 2003-07-03 | 2006-02-01 | Kortlagning genamengja starfrænna DNA þátta og frumuprótína |
Country Status (12)
Country | Link |
---|---|
US (1) | US7601492B2 (is) |
EP (1) | EP1644534A4 (is) |
JP (1) | JP2007524399A (is) |
KR (1) | KR20060052710A (is) |
CN (1) | CN1816636A (is) |
AU (1) | AU2004257191B2 (is) |
CA (1) | CA2530810A1 (is) |
IL (1) | IL172544A0 (is) |
IS (1) | IS8282A (is) |
MX (1) | MXPA05014215A (is) |
NZ (1) | NZ545000A (is) |
WO (1) | WO2005007814A2 (is) |
Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006005043A2 (en) * | 2004-06-30 | 2006-01-12 | Cemines, Inc. | Compositions and methods for detecting protein interactions with target dna sequences |
JP2007222160A (ja) * | 2006-01-26 | 2007-09-06 | National Institute Of Advanced Industrial & Technology | 生体由来試料中の蛋白質の解析方法 |
US8071296B2 (en) | 2006-03-13 | 2011-12-06 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
CA2661640A1 (en) * | 2006-08-24 | 2008-02-28 | University Of Massachusetts Medical School | Mapping of genomic interactions |
WO2008069906A2 (en) * | 2006-11-14 | 2008-06-12 | The Regents Of The University Of California | Digital expression of gene analysis |
DK2191016T3 (en) * | 2007-08-20 | 2015-06-08 | Gen Hospital Corp | INSULATION OF PROTEIN FACTORS BINDING DIRECT OR INDIRECT WITH NUCLEIC ACIDS |
US8263367B2 (en) * | 2008-01-25 | 2012-09-11 | Agency For Science, Technology And Research | Nucleic acid interaction analysis |
CN101372704B (zh) * | 2008-07-17 | 2012-07-25 | 武汉大学 | 使用量子点改进聚合酶链式反应的方法 |
WO2010082743A2 (ko) * | 2009-01-14 | 2010-07-22 | 경희대학교 산학협력단 | 가교결합과 가속 질량 분석법의 조합에 의한 단백질-리간드 상호작용의 확인 및 정량화 방법 |
JP5698471B2 (ja) * | 2009-06-30 | 2015-04-08 | シスメックス株式会社 | マイクロアレイを用いた核酸の検出方法およびマイクロアレイデータ解析用プログラム |
US9499814B2 (en) | 2010-01-22 | 2016-11-22 | The Regents Of The University Of California | Methods for identifying drug effects on a cell by determining changes in the cell's spliced message profile |
US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
PL2556171T3 (pl) | 2010-04-05 | 2016-04-29 | Prognosys Biosciences Inc | Oznaczenia biologiczne kodowane przestrzennie |
US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
WO2013188789A2 (en) * | 2012-06-14 | 2013-12-19 | Whitehead Institute For Biomedical Research | Genome-wide method of assessing interactions between chemical entities and their target molecules |
MX2015007550A (es) | 2012-12-12 | 2017-02-02 | Broad Inst Inc | Suministro, modificación y optimización de sistemas, métodos y composiciones para la manipulación de secuencias y aplicaciones terapéuticas. |
EP2931892B1 (en) | 2012-12-12 | 2018-09-12 | The Broad Institute, Inc. | Methods, models, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof |
US20140186843A1 (en) * | 2012-12-12 | 2014-07-03 | Massachusetts Institute Of Technology | Methods, systems, and apparatus for identifying target sequences for cas enzymes or crispr-cas systems for target sequences and conveying results thereof |
AU2014281026B2 (en) | 2013-06-17 | 2020-05-28 | Massachusetts Institute Of Technology | Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation |
RU2716420C2 (ru) | 2013-06-17 | 2020-03-11 | Те Брод Инститьют Инк. | Доставка и применение систем crispr-cas, векторов и композиций для целенаправленного воздействия и терапии в печени |
WO2014204727A1 (en) | 2013-06-17 | 2014-12-24 | The Broad Institute Inc. | Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof |
EP3011034B1 (en) | 2013-06-17 | 2019-08-07 | The Broad Institute, Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using viral components |
CN105492611A (zh) | 2013-06-17 | 2016-04-13 | 布罗德研究所有限公司 | 用于序列操纵的优化的crispr-cas双切口酶系统、方法以及组合物 |
US9868979B2 (en) | 2013-06-25 | 2018-01-16 | Prognosys Biosciences, Inc. | Spatially encoded biological assays using a microfluidic device |
WO2015089364A1 (en) | 2013-12-12 | 2015-06-18 | The Broad Institute Inc. | Crystal structure of a crispr-cas system, and uses thereof |
MX2016007328A (es) | 2013-12-12 | 2017-07-19 | Broad Inst Inc | Suministro, uso y aplicaciones terapeuticas de sistemas y composiciones crispr-cas para edicion del genoma. |
WO2015089486A2 (en) | 2013-12-12 | 2015-06-18 | The Broad Institute Inc. | Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems |
AU2014362248A1 (en) | 2013-12-12 | 2016-06-16 | Massachusetts Institute Of Technology | Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders |
CN107208091A (zh) * | 2014-11-11 | 2017-09-26 | 雅培分子公司 | 杂交探针和方法 |
EP3985115A1 (en) | 2014-12-12 | 2022-04-20 | The Broad Institute, Inc. | Protected guide rnas (pgrnas) |
ES2955916T3 (es) | 2015-04-10 | 2023-12-11 | Spatial Transcriptomics Ab | Análisis múltiplex de especímenes biológicos de ácidos nucleicos espacialmente distinguidos |
KR20160144153A (ko) | 2015-06-08 | 2016-12-16 | 연세대학교 산학협력단 | 생체 내 표적 dna와 전사인자 간의 결합체 추출을 통한 전사인자 검출방법 |
WO2016205759A1 (en) | 2015-06-18 | 2016-12-22 | The Broad Institute Inc. | Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation |
RU2752834C2 (ru) | 2015-06-18 | 2021-08-09 | Те Брод Инститьют, Инк. | Мутации фермента crispr, уменьшающие нецелевые эффекты |
US10984891B2 (en) * | 2016-08-05 | 2021-04-20 | The Regents Of The University Of California | Methods for global RNA-chromatin interactome discovery |
CN117402951A (zh) * | 2016-09-02 | 2024-01-16 | 路德维格癌症研究有限公司 | 染色质相互作用的全基因组鉴定 |
KR101930253B1 (ko) | 2017-01-13 | 2018-12-18 | 주식회사 클리노믹스 | 공통서열을 포함한 참조표준 게놈지도 구축 장치 및 방법 |
EP3629945A4 (en) | 2017-05-25 | 2021-03-03 | Terumo Corporation | ADHESIVE LOCKING SYSTEMS |
EP3794130A4 (en) | 2018-05-16 | 2022-07-27 | Synthego Corporation | METHODS AND SYSTEMS FOR DESIGN AND USE OF GUIDE RNA |
CN108976434B (zh) * | 2018-08-03 | 2021-02-12 | 贵州大学 | 一种基于八元瓜环的超分子框架材料的制备方法和应用 |
US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
EP3894592A2 (en) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Generating spatial arrays with gradients |
US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
EP3976820A1 (en) | 2019-05-30 | 2022-04-06 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
EP4025711A2 (en) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
EP3891300B1 (en) | 2019-12-23 | 2023-03-29 | 10X Genomics, Inc. | Methods for spatial analysis using rna-templated ligation |
US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
US11821035B1 (en) | 2020-01-29 | 2023-11-21 | 10X Genomics, Inc. | Compositions and methods of making gene expression libraries |
US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
ES2965354T3 (es) | 2020-04-22 | 2024-04-12 | 10X Genomics Inc | Métodos para análisis espacial que usan eliminación de ARN elegido como diana |
AU2021275906A1 (en) | 2020-05-22 | 2022-12-22 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
WO2021236929A1 (en) | 2020-05-22 | 2021-11-25 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
EP4158054A1 (en) | 2020-06-02 | 2023-04-05 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
WO2021247543A2 (en) | 2020-06-02 | 2021-12-09 | 10X Genomics, Inc. | Nucleic acid library methods |
EP4162074B1 (en) | 2020-06-08 | 2024-04-24 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
EP4165207A1 (en) | 2020-06-10 | 2023-04-19 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
CN116034166A (zh) | 2020-06-25 | 2023-04-28 | 10X基因组学有限公司 | Dna甲基化的空间分析 |
US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
EP4301870A1 (en) | 2021-03-18 | 2024-01-10 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3539089A (en) | 1988-04-08 | 1989-11-03 | Salk Institute For Biological Studies, The | Ligase-based amplification method |
JP2003508066A (ja) * | 1999-09-01 | 2003-03-04 | ホワイトヘッド インスチチュート フォアー バイオメディカル リサーチ | タンパク質−dna相互作用の染色体全体の解析 |
US7470507B2 (en) * | 1999-09-01 | 2008-12-30 | Whitehead Institute For Biomedical Research | Genome-wide location and function of DNA binding proteins |
US6812005B2 (en) * | 2000-02-07 | 2004-11-02 | The Regents Of The University Of California | Nucleic acid detection methods using universal priming |
WO2001062952A1 (en) * | 2000-02-24 | 2001-08-30 | Dna Sciences, Inc. | Methods for determining single nucleotide variations |
US20040209299A1 (en) * | 2003-03-07 | 2004-10-21 | Rubicon Genomics, Inc. | In vitro DNA immortalization and whole genome amplification using libraries generated from randomly fragmented DNA |
-
2004
- 2004-07-02 NZ NZ545000A patent/NZ545000A/en unknown
- 2004-07-02 US US10/561,764 patent/US7601492B2/en not_active Expired - Fee Related
- 2004-07-02 EP EP04777521A patent/EP1644534A4/en not_active Withdrawn
- 2004-07-02 JP JP2006517848A patent/JP2007524399A/ja not_active Withdrawn
- 2004-07-02 KR KR1020057024511A patent/KR20060052710A/ko not_active Application Discontinuation
- 2004-07-02 CN CNA2004800190481A patent/CN1816636A/zh active Pending
- 2004-07-02 CA CA002530810A patent/CA2530810A1/en not_active Abandoned
- 2004-07-02 AU AU2004257191A patent/AU2004257191B2/en not_active Expired - Fee Related
- 2004-07-02 MX MXPA05014215A patent/MXPA05014215A/es unknown
- 2004-07-02 WO PCT/US2004/021450 patent/WO2005007814A2/en active Application Filing
-
2005
- 2005-12-13 IL IL172544A patent/IL172544A0/en unknown
-
2006
- 2006-02-01 IS IS8282A patent/IS8282A/is unknown
Also Published As
Publication number | Publication date |
---|---|
WO2005007814A3 (en) | 2005-06-23 |
EP1644534A2 (en) | 2006-04-12 |
NZ545000A (en) | 2008-08-29 |
AU2004257191A1 (en) | 2005-01-27 |
MXPA05014215A (es) | 2006-03-13 |
CN1816636A (zh) | 2006-08-09 |
US20070059703A1 (en) | 2007-03-15 |
IL172544A0 (en) | 2006-04-10 |
WO2005007814A2 (en) | 2005-01-27 |
JP2007524399A (ja) | 2007-08-30 |
AU2004257191B2 (en) | 2009-05-07 |
CA2530810A1 (en) | 2005-01-27 |
US7601492B2 (en) | 2009-10-13 |
KR20060052710A (ko) | 2006-05-19 |
EP1644534A4 (en) | 2006-08-09 |
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