IN2015DN03093A - - Google Patents

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Publication number
IN2015DN03093A
IN2015DN03093A IN3093DEN2015A IN2015DN03093A IN 2015DN03093 A IN2015DN03093 A IN 2015DN03093A IN 3093DEN2015 A IN3093DEN2015 A IN 3093DEN2015A IN 2015DN03093 A IN2015DN03093 A IN 2015DN03093A
Authority
IN
India
Prior art keywords
reactor chambers
strategies
concentrations
contain
certain embodiments
Prior art date
Application number
Other languages
English (en)
Inventor
Shireen; Goh
Rajeev Jagga; Ram
Horst; Blum
Michelangelo; Canzoneri
Original Assignee
Massachusetts Inst Technology
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Sanofi Sa filed Critical Massachusetts Inst Technology
Publication of IN2015DN03093A publication Critical patent/IN2015DN03093A/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06Nozzles; Sprayers; Spargers; Diffusers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/32Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of substances in solution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Treating Waste Gases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN3093DEN2015 2012-10-26 2013-10-25 IN2015DN03093A (enExample)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261719027P 2012-10-26 2012-10-26
US201361869111P 2013-08-23 2013-08-23
EP13306462 2013-10-23
PCT/US2013/066832 WO2014066774A1 (en) 2012-10-26 2013-10-25 Control of carbon dioxide levels and ph in small volume reactors

Publications (1)

Publication Number Publication Date
IN2015DN03093A true IN2015DN03093A (enExample) 2015-10-02

Family

ID=49551567

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3093DEN2015 IN2015DN03093A (enExample) 2012-10-26 2013-10-25

Country Status (10)

Country Link
US (2) US20140127802A1 (enExample)
EP (1) EP2912157A1 (enExample)
CN (2) CN104870629A (enExample)
AU (3) AU2013334168B2 (enExample)
CA (1) CA2888076C (enExample)
HK (1) HK1213006A1 (enExample)
IN (1) IN2015DN03093A (enExample)
MX (2) MX378896B (enExample)
SG (2) SG10201803572UA (enExample)
WO (1) WO2014066774A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009060489A1 (de) * 2009-12-29 2011-06-30 Uhde GmbH, 44141 Vorrichtung und Verfahren zur Regelung der Sauerstoffpermeation durch nicht-poröse Sauerstoffanionen leitende keramische Membranen und deren Verwendung
CN114106988A (zh) * 2012-10-26 2022-03-01 麻省理工学院 化学反应器中的湿度控制
EP3036317A4 (en) 2013-08-23 2017-04-12 Massachusetts Institute of Technology Small volume bioreactors with substantially constant working volumes and associated systems and methods
US10296718B2 (en) 2014-05-30 2019-05-21 Hitachi, Ltd. Medicine production support system and medicine production support method
CN104128152B (zh) * 2014-08-12 2015-09-09 青海合杰工贸集团有限责任公司 一种调配反应观察装置
US20210146353A1 (en) * 2017-03-14 2021-05-20 BioGenium Microsystems Oy A system and a method for irradiating biological material
CN109517738A (zh) * 2018-12-14 2019-03-26 杭州奕安济世生物药业有限公司 一种调控生物反应器中二氧化碳含量的方法
CN114989977A (zh) * 2022-06-16 2022-09-02 中山大学 一种用于多细胞相互作用及药物筛选的肿瘤类器官芯片及其制备方法
JP7430005B1 (ja) * 2022-11-24 2024-02-09 株式会社シェルタージャパン 藻類増殖制御装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3080647B2 (ja) * 1990-10-09 2000-08-28 エーザイ株式会社 細胞培養装置
FR2803852B1 (fr) * 2000-01-17 2004-11-05 Farzin Sarem Dispositif de culture cellulaire et tissulaire a circulation de fluide de culture controlee
WO2003093406A2 (en) * 2002-05-01 2003-11-13 Massachusetts Institute Of Technology Microfermentors for rapid screening and analysis of biochemical processes
WO2005026349A1 (ja) * 2003-09-17 2005-03-24 Mitsubishi Chemical Corporation 非アミノ有機酸の製造方法
US7367550B2 (en) 2003-11-18 2008-05-06 Massachusetts Institute Of Technology Peristaltic mixing and oxygenation system
WO2005065419A2 (en) * 2003-12-29 2005-07-21 Am Biosolutions Method of culturing cells
WO2005121307A2 (en) * 2004-06-07 2005-12-22 Bioprocessor Corp. Gas control in a microreactor
CN1763173A (zh) * 2005-07-21 2006-04-26 高春平 造血干细胞培养装置和方法
US9248421B2 (en) * 2005-10-07 2016-02-02 Massachusetts Institute Of Technology Parallel integrated bioreactor device and method
US8178318B2 (en) * 2008-08-06 2012-05-15 Praxair Technology, Inc. Method for controlling pH, osmolality and dissolved carbon dioxide levels in a mammalian cell culture process to enhance cell viability and biologic product yield
PL2451936T3 (pl) * 2009-07-06 2020-02-28 F. Hoffmann-La Roche Ag Sposób hodowli komórek eukariotycznych

Also Published As

Publication number Publication date
CA2888076A1 (en) 2014-05-01
WO2014066774A1 (en) 2014-05-01
MX378896B (es) 2025-03-11
AU2013334168B2 (en) 2018-10-04
CN104870629A (zh) 2015-08-26
HK1213006A1 (zh) 2016-06-24
CN107267385B (zh) 2021-03-12
AU2018286560B2 (en) 2020-07-23
CN107267385A (zh) 2017-10-20
US20170107473A1 (en) 2017-04-20
AU2013334168A1 (en) 2015-04-30
AU2020250287B2 (en) 2022-07-21
AU2018286560A1 (en) 2019-01-24
CA2888076C (en) 2023-08-08
EP2912157A1 (en) 2015-09-02
US20140127802A1 (en) 2014-05-08
MX2015005284A (es) 2015-11-16
SG11201502917TA (en) 2015-05-28
AU2020250287A1 (en) 2020-11-05
SG10201803572UA (en) 2018-06-28
MX2020014123A (es) 2021-03-25

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