IN2015DN01046A - - Google Patents
Download PDFInfo
- Publication number
- IN2015DN01046A IN2015DN01046A IN1046DEN2015A IN2015DN01046A IN 2015DN01046 A IN2015DN01046 A IN 2015DN01046A IN 1046DEN2015 A IN1046DEN2015 A IN 1046DEN2015A IN 2015DN01046 A IN2015DN01046 A IN 2015DN01046A
- Authority
- IN
- India
- Prior art keywords
- breast cancer
- treating
- subject
- subject suffering
- positive
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 abstract 11
- 208000026310 Breast neoplasm Diseases 0.000 abstract 10
- 229940083324 Selective androgen receptor modulator Drugs 0.000 abstract 3
- 239000000849 selective androgen receptor modulator Substances 0.000 abstract 3
- BFYIZQONLCFLEV-DAELLWKTSA-N Aromasine Chemical compound O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC(=C)C2=C1 BFYIZQONLCFLEV-DAELLWKTSA-N 0.000 abstract 2
- 206010055113 Breast cancer metastatic Diseases 0.000 abstract 2
- NKANXQFJJICGDU-QPLCGJKRSA-N Tamoxifen Chemical compound C=1C=CC=CC=1C(/CC)=C(C=1C=CC(OCCN(C)C)=CC=1)/C1=CC=CC=C1 NKANXQFJJICGDU-QPLCGJKRSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229960002087 pertuzumab Drugs 0.000 abstract 2
- 230000004083 survival effect Effects 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 229940122815 Aromatase inhibitor Drugs 0.000 abstract 1
- VWUXBMIQPBEWFH-WCCTWKNTSA-N Fulvestrant Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)CC2=C1 VWUXBMIQPBEWFH-WCCTWKNTSA-N 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 208000003721 Triple Negative Breast Neoplasms Diseases 0.000 abstract 1
- 102000001307 androgen receptors Human genes 0.000 abstract 1
- 108010080146 androgen receptors Proteins 0.000 abstract 1
- 229940087620 aromasin Drugs 0.000 abstract 1
- 239000003886 aromatase inhibitor Substances 0.000 abstract 1
- 229940120638 avastin Drugs 0.000 abstract 1
- 229960000397 bevacizumab Drugs 0.000 abstract 1
- 229960000255 exemestane Drugs 0.000 abstract 1
- 229960002258 fulvestrant Drugs 0.000 abstract 1
- 229940022353 herceptin Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 abstract 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 abstract 1
- 229960001603 tamoxifen Drugs 0.000 abstract 1
- 229960005026 toremifene Drugs 0.000 abstract 1
- XFCLJVABOIYOMF-QPLCGJKRSA-N toremifene Chemical compound C1=CC(OCCN(C)C)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 XFCLJVABOIYOMF-QPLCGJKRSA-N 0.000 abstract 1
- 229960000575 trastuzumab Drugs 0.000 abstract 1
- 229960001612 trastuzumab emtansine Drugs 0.000 abstract 1
- 208000022679 triple-negative breast carcinoma Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/02—Carbamic acids; Salts of carbamic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261671366P | 2012-07-13 | 2012-07-13 | |
US201261726274P | 2012-11-14 | 2012-11-14 | |
PCT/US2013/029667 WO2014011220A2 (en) | 2012-07-13 | 2013-03-07 | A method of treating androgen receptor (ar)-positive breast cancers with selective androgen receptor modulator (sarms) |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2015DN01046A true IN2015DN01046A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-06-26 |
Family
ID=49914508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN1046DEN2015 IN2015DN01046A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2012-07-13 | 2013-03-07 |
Country Status (20)
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9884038B2 (en) | 2004-06-07 | 2018-02-06 | University Of Tennessee Research Foundation | Selective androgen receptor modulator and methods of use thereof |
CA2626337C (en) | 2005-10-19 | 2015-12-29 | Chavah Pty Ltd | Reduction of side effects from aromatase inhibitors used for treating breast cancer |
US9730908B2 (en) | 2006-08-24 | 2017-08-15 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US9844528B2 (en) | 2006-08-24 | 2017-12-19 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US10010521B2 (en) | 2006-08-24 | 2018-07-03 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
IN2015DN01046A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2012-07-13 | 2015-06-26 | Gtx Inc | |
US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
JP5958483B2 (ja) * | 2013-07-31 | 2016-08-02 | 株式会社村田製作所 | 電力増幅モジュール |
CA2964371A1 (en) * | 2014-10-16 | 2016-04-21 | Gtx, Inc. | Methods of treating urological disorders using sarms |
CN113633644A (zh) | 2014-10-22 | 2021-11-12 | 哈瓦赫治疗有限公司 | 降低乳房摄影乳腺密度和/或乳腺癌风险的方法 |
US10471023B2 (en) | 2015-03-12 | 2019-11-12 | British Columbia Cancer Agency Branch | Bisphenol ether derivatives and methods for using the same |
FI3283058T3 (fi) * | 2015-04-16 | 2023-03-01 | Novartis Ag | Ribosiklibitabletti |
US10865184B2 (en) | 2015-04-21 | 2020-12-15 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10654809B2 (en) | 2016-06-10 | 2020-05-19 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US9834507B2 (en) | 2015-04-21 | 2017-12-05 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
CA2983426C (en) | 2015-04-21 | 2023-10-17 | Gtx, Inc. | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
US10035763B2 (en) | 2015-04-21 | 2018-07-31 | Gtx, Inc. | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
BR112017022860A2 (pt) * | 2015-04-21 | 2018-07-17 | Gtx Inc | ligantes de decompostos receptores de andrógeno seletivos (sard) e métodos de utilização dos mesmos |
US10093613B2 (en) | 2015-04-21 | 2018-10-09 | Gtx, Inc. | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10017471B2 (en) | 2015-04-21 | 2018-07-10 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10441570B2 (en) | 2015-04-21 | 2019-10-15 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) Ligands and methods of use thereof |
US10806720B2 (en) | 2015-04-21 | 2020-10-20 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
SG11201803260PA (en) | 2015-10-22 | 2018-05-30 | Havah Therapeutics Pty Ltd | Methods of reducing mammographic breast density and/or breast cancer risk |
MX392461B (es) | 2016-04-01 | 2025-03-11 | Recurium Ip Holdings Llc | Moduladores de receptores estrogénicos |
US20170298033A1 (en) | 2016-04-15 | 2017-10-19 | The University Of British Columbia | Bisphenol derivatives and their use as androgen receptor activity modulators |
AU2017278314B2 (en) * | 2016-06-10 | 2022-06-30 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US11230523B2 (en) | 2016-06-10 | 2022-01-25 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
US10806719B2 (en) | 2016-06-10 | 2020-10-20 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (SARD) ligands and methods of use thereof |
NZ759691A (en) * | 2017-06-29 | 2023-05-26 | G1 Therapeutics Inc | Morphic forms of git38 and methods of manufacture thereof |
EP3793608A4 (en) | 2018-05-14 | 2022-04-20 | Nuvation Bio Inc. | COMPOUNDS TARGETING ANTICANCER NUCLEAR HORMONE RECEPTORS |
WO2019226991A1 (en) | 2018-05-25 | 2019-11-28 | Essa Pharma, Inc. | Androgen receptor modulators and methods for their use |
WO2020051344A1 (en) | 2018-09-05 | 2020-03-12 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
CN109761778A (zh) * | 2018-12-10 | 2019-05-17 | 石家庄市度智医药科技有限公司 | 一种合成光学活性α-羟基丙酰胺衍生物的方法 |
WO2020198712A1 (en) | 2019-03-28 | 2020-10-01 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
US20220202780A1 (en) * | 2019-03-28 | 2022-06-30 | Essa Pharma, Inc. | Pharmaceutical compositions and combinations comprising inhibitors of the androgen receptor and uses thereof |
WO2020205608A1 (en) * | 2019-03-29 | 2020-10-08 | Emory University | Uses of androgen receptor antagonists and jnk pathway inhibitors, and pharmaceutical compositions related thereto |
MX2021013774A (es) | 2019-05-14 | 2021-12-10 | Nuvation Bio Inc | Compuestos anticancerigenos dirigidos a los receptores hormonales nucleares. |
WO2020243373A1 (en) * | 2019-05-29 | 2020-12-03 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
AU2020287392A1 (en) | 2019-06-03 | 2021-12-23 | Havah Therapeutics Pty Ltd | Pharmaceutical formulations and systems for delivery of an androgenic agent and an aromatase inhibitor and methods for use |
CN114269342A (zh) | 2019-08-06 | 2022-04-01 | 里科瑞尔姆Ip控股有限责任公司 | 用于治疗突变的雌激素受体调节剂 |
CA3173036A1 (en) * | 2020-02-25 | 2021-09-02 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) ligands and methods of use thereof |
US20210323931A1 (en) | 2020-04-17 | 2021-10-21 | Essa Pharma, Inc. | Solid forms of an n-terminal domain androgen receptor inhibitor and uses thereof |
IL297216A (en) * | 2020-04-24 | 2022-12-01 | Astrazeneca Ab | Dosage regimen for cancer treatment |
WO2023101710A1 (en) * | 2021-12-02 | 2023-06-08 | Veru Inc. | Methods of treating breast cancers with selective androgen receptor modulators and additional therapeutic agents |
WO2023172891A2 (en) * | 2022-03-07 | 2023-09-14 | Baylor College Of Medicine | Biomarkers for combination therapy for er+ breast cancer |
WO2023244059A1 (en) * | 2022-06-15 | 2023-12-21 | Ildong Pharmaceutical Co., Ltd. | Methods of treating cancer using dual androgen receptor and pde5 inhibitor compounds |
WO2024138077A1 (en) * | 2022-12-21 | 2024-06-27 | Duke University | Coadministration of estrogen with estrogen receptor modulator or degrader or er targeted protac for the treatment of estrogen responsive cancers |
Family Cites Families (163)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3256096A (en) | 1961-08-11 | 1966-06-14 | Organic Nutrients Inc | Anabolic stimulator as a poultry feed supplement |
US3239345A (en) | 1965-02-15 | 1966-03-08 | Estrogenic compounds and animal growth promoters | |
US3949085A (en) | 1970-05-27 | 1976-04-06 | Chinoin Gyogyszer-Es Vegyeszeti Termakek Gyara Rt | Anabolic-weight-gain promoting compositions containing isoflavone derivatives and method using same |
US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
GB1360001A (en) | 1971-06-16 | 1974-07-17 | Scherico Ltd | Pharmaceutical compositions comprising substituted anilides |
US3875229A (en) | 1972-11-24 | 1975-04-01 | Schering Corp | Substituted carboxanilides |
US3865801A (en) | 1973-06-15 | 1975-02-11 | Atomic Energy Commission | Stabilization of urinary erythropoietin using sodium p-aminosalicylate and extracting into phenol |
US3946109A (en) | 1973-08-08 | 1976-03-23 | Ernst Kolb | Animal feed composition containing certain vitamin combinations |
US4036979A (en) | 1974-01-25 | 1977-07-19 | American Cyanamid Company | Compositions containing 4,5,6,7-tetrahydrobenz[b]thien-4-yl-ureas or derivatives and methods of enhancing growth rate |
US4211781A (en) | 1974-09-23 | 1980-07-08 | Pfizer Inc. | Process for the preparation of dustless quinoxaline-1,4-dioxide animal feed supplement premixes |
US3991750A (en) | 1975-04-28 | 1976-11-16 | Syntex Corporation | Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals |
JPS6044294B2 (ja) | 1976-04-15 | 1985-10-02 | 帝国臓器製薬株式会社 | アニリド誘導体 |
US4139638A (en) | 1976-09-23 | 1979-02-13 | Schering Corporation | Methods for the treatment of hirsutism |
EP0002309B1 (en) | 1977-10-12 | 1982-12-01 | Imperial Chemical Industries Plc | Acylanilides, process for their manufacture and pharmaceutical and veterinary compositions containing them |
US4191775A (en) | 1977-12-15 | 1980-03-04 | Imperial Chemical Industries Limited | Amide derivatives |
US4447421A (en) | 1980-05-08 | 1984-05-08 | American Cyanamid Company | Process for the preparation of medicated animal feed supplement |
NZ197008A (en) | 1980-05-22 | 1984-10-19 | Ici Ltd | Acylanilide derivatives and pharmaceutical compositions |
JPS57171904A (en) | 1981-04-15 | 1982-10-22 | Mitsubishi Petrochem Co Ltd | Tri- or tetra-substituted phenoxycarboxylic acid anilide type herbicide |
LU88769I2 (fr) | 1982-07-23 | 1996-11-05 | Zeneca Ltd | Bicalutamide et ses sels et esters pharmaceutiquement acceptables (Casodex (R)) |
KR850004274A (ko) | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
FR2576025B1 (fr) | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
US4670249A (en) | 1985-04-12 | 1987-06-02 | International Minerals & Chemical Corp. | Growth-promoting compositions |
US4837004A (en) | 1985-10-18 | 1989-06-06 | Eastman Kodak Company | Rumen-stable pellets |
US4904473A (en) | 1986-06-23 | 1990-02-27 | International Minerals & Chemical Corp. | Ruminant feed antacid containing potassium, sodium and chlorine |
GB8617652D0 (en) | 1986-07-18 | 1986-08-28 | Ici Plc | Acylanilide derivatives |
GB8617653D0 (en) | 1986-07-18 | 1986-08-28 | Ici Plc | Amide derivatives |
US4849447A (en) | 1987-10-13 | 1989-07-18 | Pitman-Moore, Inc. | Zearalanol derivatives with anabolic activity |
WO1989007111A1 (en) | 1988-01-28 | 1989-08-10 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
WO1989007110A1 (en) | 1988-01-28 | 1989-08-10 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
US4977288A (en) | 1988-01-29 | 1990-12-11 | President And Fellows Of Harvard College | M-aminophenyltrialkylstannane |
US5162504A (en) | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
US5179080A (en) | 1989-08-31 | 1993-01-12 | Clinical Homecare, Corp. | Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease |
KR100263845B1 (ko) | 1989-10-13 | 2000-08-16 | 스튜어트 엘.왓트 | 에리트로포이에틴 동형체와 그의 제조방법 및 그를 포함하는제약학적 조성물 |
US5030657A (en) | 1989-10-23 | 1991-07-09 | University Of Georgia Research Foundation, Inc. | L-carnitine supplemented catfish diet |
US5288496A (en) | 1990-05-15 | 1994-02-22 | Stolle Research & Development Corporation | Growth promoters for animals |
US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
JPH09508125A (ja) | 1994-01-21 | 1997-08-19 | セプラコー,インコーポレイテッド | 光学的純正r−(−)−カソデックスを使用した男性ホルモン依存疾患治療のための方法と組成 |
US5609849A (en) | 1994-03-11 | 1997-03-11 | The Trustees Of The University Of Pennsylvania | Serotonin (5-HT1A) receptor ligands and imaging agents |
EP0683172B1 (en) | 1994-05-19 | 1997-08-13 | Akzo Nobel N.V. | 11,21-Bisphenyl-19-norpregnane derivatives |
US5612359A (en) | 1994-08-26 | 1997-03-18 | Bristol-Myers Squibb Company | Substituted biphenyl isoxazole sulfonamides |
US5656651A (en) | 1995-06-16 | 1997-08-12 | Biophysica Inc. | Androgenic directed compositions |
WO1998005962A1 (en) | 1996-08-02 | 1998-02-12 | Panvera Corporation | A method for quantitating competitive binding of molecules to proteins utilizing fluorescence polarization |
US20050038110A1 (en) | 2000-08-24 | 2005-02-17 | Steiner Mitchell S. | Selective androgen receptor modulators and methods of use thereof |
US7205437B2 (en) | 1996-11-27 | 2007-04-17 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US7759520B2 (en) | 1996-11-27 | 2010-07-20 | University Of Tennessee Research Foundation | Synthesis of selective androgen receptor modulators |
US7518013B2 (en) | 2000-08-24 | 2009-04-14 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US6071957A (en) | 1996-11-27 | 2000-06-06 | The University Of Tennessee Research Corporation | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer |
US6492554B2 (en) | 2000-08-24 | 2002-12-10 | The University Of Tennessee Research Corporation | Selective androgen receptor modulators and methods of use thereof |
US6995284B2 (en) | 2000-08-24 | 2006-02-07 | The University Of Tennessee Research Foundation | Synthesis of selective androgen receptor modulators |
US20090264534A1 (en) | 1996-11-27 | 2009-10-22 | Dalton James T | Selective androgen receptor modulators |
AU5729098A (en) | 1996-12-24 | 1998-07-17 | Zymogenetics Inc. | Treatment agents and methods for treating type ii diabetes and symptoms of type ii diabetes |
TW536540B (en) | 1997-01-30 | 2003-06-11 | Bristol Myers Squibb Co | Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe |
US6160011A (en) | 1997-05-30 | 2000-12-12 | The University Of Tennessee Research Corporation | Non-steroidal agonist compounds and their use in male hormone therapy |
AU7723198A (en) | 1997-06-04 | 1998-12-21 | University Of Tennessee Research Corporation, The | Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging |
EP0903146A1 (en) | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
US6022137A (en) | 1998-04-29 | 2000-02-08 | Buckeye Feed Mills, Inc. | Conditioner for processing raw grain composition to produce pelletized feed |
DE69940063D1 (de) | 1998-07-06 | 2009-01-22 | Bristol Myers Squibb Co | Biphenylsulfonamide als zweifach aktive rezeptor antagonisten von angiotensin und endothelin |
ATE242007T1 (de) | 1998-12-23 | 2003-06-15 | Searle Llc | Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen |
HRP20010688B1 (en) | 1999-03-29 | 2008-10-31 | F. Hoffmann - La Roche Ag | Glucokinase activators |
US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
CA2388253A1 (en) | 1999-10-14 | 2001-04-19 | Bristol-Myers Squibb Company | Crystallographic structure of the androgen receptor ligand binding domain |
US7037919B1 (en) | 1999-10-14 | 2006-05-02 | Kaken Pharmaceutical Co. Ltd. | Tetrahydroquinoline derivatives |
EP1222165A2 (en) | 1999-10-19 | 2002-07-17 | Nobex Corporation | Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof |
JP4778178B2 (ja) | 1999-10-27 | 2011-09-21 | バイオコン・リミテッド | 実質的に純粋なビカルタミドの合成における中間体の分割 |
US6353111B1 (en) | 1999-12-15 | 2002-03-05 | Hoffmann-La Roche Inc. | Trans olefinic glucokinase activators |
WO2001049709A1 (en) | 2000-01-03 | 2001-07-12 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Glycogen synthase kinase-3 inhibitors |
US6441197B1 (en) | 2000-01-20 | 2002-08-27 | Daiichi Pure Chemicals Co., Ltd. | Diaminofluorescein derivative |
US6395767B2 (en) | 2000-03-10 | 2002-05-28 | Bristol-Myers Squibb Company | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method |
US7713989B2 (en) | 2000-04-27 | 2010-05-11 | Dow Robert L | Glucocorticoid receptor modulators |
HUP0303172A3 (en) | 2000-06-28 | 2006-05-29 | Bristol Myers Squibb Co | Selective androgen receptor modulators and methods for their identification, desing and use |
US7645898B2 (en) | 2000-08-24 | 2010-01-12 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and method of use thereof |
US6838484B2 (en) | 2000-08-24 | 2005-01-04 | University Of Tennessee Research Foundation | Formulations comprising selective androgen receptor modulators |
US7855229B2 (en) | 2000-08-24 | 2010-12-21 | University Of Tennessee Research Foundation | Treating wasting disorders with selective androgen receptor modulators |
SI1401801T1 (sl) | 2000-08-24 | 2007-04-30 | Univ Tennessee Res Foundation | Selektivni modulatorji androgenskega receptorja in postopki za njihovo uporabo |
US7622503B2 (en) | 2000-08-24 | 2009-11-24 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US6998500B2 (en) | 2000-08-24 | 2006-02-14 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US20070173546A1 (en) | 2000-08-24 | 2007-07-26 | Dalton James T | Selective androgen receptor modulators and method of use thereof |
US20020173495A1 (en) | 2000-08-24 | 2002-11-21 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
US8445534B2 (en) | 2000-08-24 | 2013-05-21 | University Of Tennessee Research Foundation | Treating androgen decline in aging male (ADAM)-associated conditions with SARMs |
US20030232792A1 (en) | 2000-08-24 | 2003-12-18 | Dalton James T. | Selective androgen receptor modulators and methods of use thereof |
US7026500B2 (en) | 2000-08-24 | 2006-04-11 | University Of Tennessee Research Foundation | Halogenated selective androgen receptor modulators and methods of use thereof |
US20040260108A1 (en) | 2001-06-25 | 2004-12-23 | Dalton James T. | Metabolites of selective androgen receptor modulators and methods of use thereof |
US7919647B2 (en) | 2000-08-24 | 2011-04-05 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
US8008348B2 (en) | 2001-12-06 | 2011-08-30 | University Of Tennessee Research Foundation | Treating muscle wasting with selective androgen receptor modulators |
US20030229099A1 (en) | 2000-08-30 | 2003-12-11 | Zhu Hugh Y. | Novel farnesyl protein transferase inhibitors as antitumor agents |
WO2002020463A2 (en) | 2000-09-05 | 2002-03-14 | Tularik Inc. | Fxr modulators |
JPWO2002022585A1 (ja) | 2000-09-14 | 2004-01-22 | 科研製薬株式会社 | テトラヒドロキノリン化合物 |
SE0102300D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
SE0102299D0 (sv) | 2001-06-26 | 2001-06-26 | Astrazeneca Ab | Compounds |
US6645974B2 (en) | 2001-07-31 | 2003-11-11 | Merck & Co., Inc. | Androgen receptor modulators and methods for use thereof |
DE60239207D1 (de) | 2001-08-10 | 2011-03-31 | Takeda Pharmaceutical | Gnrh-agonistische kombinationsmittel |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
US20060004042A1 (en) | 2001-08-23 | 2006-01-05 | Dalton James T | Formulations comprising selective androgen receptor modulators |
SI1666033T1 (sl) | 2001-11-29 | 2009-06-30 | Gtx Inc | Preprečevanje in zdravljenje s pomankanjem androgena inducirane osteoporoze |
JP4605557B2 (ja) | 2001-12-06 | 2011-01-05 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 選択的アンドロゲンレセプタ修飾因子を用いた筋萎縮治療 |
US20070161608A1 (en) | 2001-12-06 | 2007-07-12 | Dalton James T | Selective androgen receptor modulators for treating muscle wasting |
US8853266B2 (en) | 2001-12-06 | 2014-10-07 | University Of Tennessee Research Foundation | Selective androgen receptor modulators for treating diabetes |
AU2003207717B9 (en) | 2002-02-01 | 2009-05-07 | Merck & Co., Inc. | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia |
RS69704A (en) | 2002-02-07 | 2006-12-15 | Gtx Inc. | Treating bening prostate hyperplasia with sarms |
EA013818B1 (ru) | 2002-02-28 | 2010-08-30 | Юниверсити Оф Теннесси Рисерч Фаундейшн | Полизамещённые селективные модуляторы рецептора андрогенов и способы их применения |
US7772433B2 (en) | 2002-02-28 | 2010-08-10 | University Of Tennessee Research Foundation | SARMS and method of use thereof |
US7344700B2 (en) | 2002-02-28 | 2008-03-18 | University Of Tennessee Research Corporation | Radiolabeled selective androgen receptor modulators and their use in prostate cancer imaging and therapy |
US7803970B2 (en) * | 2002-02-28 | 2010-09-28 | University Of Tennessee Research Foundation | Multi-substitued selective androgen receptor modulators and methods of use thereof |
BR0307981A (pt) | 2002-02-28 | 2006-01-17 | Univ Tennessee Res Foundation | Compostos substituìdos de haloacetamida e azida e seus métodos de uso |
JP5113979B2 (ja) | 2002-02-28 | 2013-01-09 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | 複数置換の選択的アンドロゲンレセプタ修飾因子及びその使用方法 |
BR0308355A (pt) | 2002-03-13 | 2005-01-25 | Merck & Co Inc | Composto ou um sal farmaceuticamente aceitável ou um seu enanciÈmero, métodos para modular uma função mediada pelo receptor de androgênio em um mamìfero em necessidade de tal modulação, para ativar a função do receptor de androgênio em um mamìfero em necessidade de tal ativação, para tratar uma condição em um mamìfero, e para tratar osteoporose em um mamìfero em sua necessidade, composição farmacêutica, métodos para aumentar a densidade mineral óssea em um mamìfero em necessidade disto, para reduzir o risco de fraturas vertebrais ou não vertebrais em um mamìfero em necessidade disto, e para produzir um marcador de modificação óssea em um mamìfero em necessidade disto, processo para produzir uma composição farmacêutica, e, método para tratar ou prevenir uma condição artrìtica em um mamìfero em necessidade disto |
AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
KR20050010059A (ko) | 2002-06-17 | 2005-01-26 | 유니버시티 오브 테네시 리서치 파운데이션 | N-결합된 선택적 안드로겐 수용체 조절자 및 그의 사용방법 |
EP1398029A1 (en) | 2002-09-10 | 2004-03-17 | LION Bioscience AG | NR3B1 nuclear receptor binding 3-substituted pyrazole derivatives |
JP2006506369A (ja) | 2002-10-15 | 2006-02-23 | ユニバーシティ・オブ・テネシー・リサーチ・ファウンデーション | メチレン架橋選択的アンドロゲン受容体調節剤及びその使用方法 |
JP2006505563A (ja) | 2002-10-15 | 2006-02-16 | ジーティーエックス・インコーポレイテッド | 選択的アンドロゲン受容体調節剤による肥満治療 |
US20040197928A1 (en) | 2002-10-15 | 2004-10-07 | Dalton James T. | Method for detecting selective androgen receptor modulators |
US20040265916A1 (en) | 2002-10-15 | 2004-12-30 | Dalton James T. | Method for detecting selective androgen receptor modulators |
EP1562906A4 (en) | 2002-10-15 | 2009-12-02 | Univ Tennessee Res Foundation | HETEROCYCLIC SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHOD FOR THEIR USE |
US20040087810A1 (en) | 2002-10-23 | 2004-05-06 | Dalton James T. | Irreversible selective androgen receptor modulators and methods of use thereof |
US20140011774A1 (en) | 2002-12-05 | 2014-01-09 | University Of Tennessee Research Foundation | Selective androgen receptor modulators |
US8309603B2 (en) | 2004-06-07 | 2012-11-13 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
WO2004060146A2 (en) | 2002-12-30 | 2004-07-22 | Purdue Research Foundation | Method of treatment for central nervous system injury |
ES2420129T3 (es) | 2003-01-13 | 2013-08-22 | University Of Tennessee Research Foundation | Síntesis en gran escala de moduladores selectivos del receptor de andrógenos |
AU2004207492A1 (en) * | 2003-01-22 | 2004-08-12 | Gtx Inc. | A method of treating breast cancer with androgen receptor antagonists |
WO2004064747A2 (en) * | 2003-01-22 | 2004-08-05 | Gtx Inc. | Treating androgen deficiency in female (adif)-associated conditions with sarms |
US20040167103A1 (en) * | 2003-02-24 | 2004-08-26 | Dalton James T. | Haloacetamide and azide substituted compounds and methods of use thereof |
GB0308335D0 (en) | 2003-04-10 | 2003-05-14 | Novartis Ag | Organic compounds |
CN1325506C (zh) | 2003-05-15 | 2007-07-11 | 中国科学院上海药物研究所 | 骨重吸收抑制剂阿伦膦酸及生理可接受的盐和它的制备 |
US20060165744A1 (en) | 2003-05-22 | 2006-07-27 | Neopharm, Inc | Combination liposomal formulations |
FI20030958A0 (fi) | 2003-06-27 | 2003-06-27 | Orion Corp | Uusia yhdisteitä |
AU2004272004B2 (en) | 2003-09-10 | 2009-01-22 | Merck Sharp & Dohme Corp. | 17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators |
AU2004271740B2 (en) | 2003-09-12 | 2010-10-28 | Merck Serono Sa | Benzothiazole derivatives for the treatment of diabetes |
EP2476415A3 (en) | 2003-10-14 | 2012-08-29 | University of Tennessee Research Foundation | Treating bone-related disorders with selective androgen receptor modulators |
US20050137172A1 (en) * | 2003-10-15 | 2005-06-23 | Dalton James T. | Haloacetamide and azide substituted compounds and methods of use thereof |
TW200523235A (en) | 2003-10-15 | 2005-07-16 | Gtx Inc | Anti-cancer compounds and methods of use thereof |
GB0325402D0 (en) | 2003-10-31 | 2003-12-03 | Astrazeneca Ab | Compounds |
CA2522874A1 (en) | 2003-12-16 | 2005-07-07 | Gtx, Inc. | Prodrugs of selective androgen receptor modulators and methods of use thereof |
TW200530181A (en) | 2004-01-13 | 2005-09-16 | Bristol Myers Squibb Co | Heterocyclic compounds useful as growth hormone secretagogues |
ATE439357T1 (de) | 2004-05-03 | 2009-08-15 | Hoffmann La Roche | Indolylderivate als liver-x-rezeptormodulatoren |
US20110237664A1 (en) * | 2004-06-07 | 2011-09-29 | Dalton James T | Selective androgen receptor modulators for treating diabetes |
US20130034562A1 (en) | 2004-06-07 | 2013-02-07 | Dalton James T | Selective androgen receptor modulators for treating diabetes |
WO2005120483A2 (en) | 2004-06-07 | 2005-12-22 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
BRPI0513367A (pt) | 2004-07-14 | 2008-05-06 | Janssen Pharmaceutica Nv | arilidenos para o tratamento de doenças mediadas pelo receptor alfa relacionado a estrogênio |
US7825229B2 (en) | 2005-03-25 | 2010-11-02 | Rosetta Genomics Ltd. | Lung cancer-related nucleic acids |
AU2006285026B2 (en) | 2005-08-31 | 2012-08-09 | University Of Tennessee Research Foundation | Treating renal disease, burns, wounds and spinal cord injury with selective androgen receptor modulators |
JP2009513704A (ja) | 2005-11-01 | 2009-04-02 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | グルコキナーゼのアロステリックモジュレーターとしての置換ジヒドロイソインドロン |
US7531671B2 (en) | 2005-11-01 | 2009-05-12 | Janssen Pharmaceutica N.V. | Dihydroisoindolones as allosteric modulators of glucokinase |
US8158828B2 (en) | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
US20070135407A1 (en) | 2005-11-28 | 2007-06-14 | Steiner Mitchell S | Serm reduction of lipid profiles |
EP1962835A2 (en) | 2005-12-21 | 2008-09-03 | Schering Corporation | Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and/or h3 receptor antagonist/inverse agonist |
EP1801140A1 (en) | 2005-12-22 | 2007-06-27 | Mnemoscience GmbH | Macro-diacrylate |
US8168216B2 (en) * | 2006-03-22 | 2012-05-01 | Medigene Ag | Treatment of triple receptor negative breast cancer |
ES2780193T3 (es) | 2006-07-12 | 2020-08-24 | Univ Tennessee Res Found | Compuesto para tratar el cáncer de mama y afecciones dependientes de la progestina |
MX2009001962A (es) | 2006-08-24 | 2009-04-30 | Univ Tennessee Res Foundation | Acilanilidas substituidas y metodos de uso de las mismas. |
CA2676066C (en) | 2007-01-22 | 2016-06-28 | Gtx, Inc. | Nuclear receptor binding agents |
US9623021B2 (en) | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
MX336760B (es) | 2007-09-11 | 2016-01-29 | Univ Tennessee Res Foundation | Formas solidas de moduladores selectivos de receptor de androgenos. |
US7968603B2 (en) | 2007-09-11 | 2011-06-28 | University Of Tennessee Research Foundation | Solid forms of selective androgen receptor modulators |
US8003689B2 (en) | 2008-06-20 | 2011-08-23 | Gtx, Inc. | Metabolites of selective androgen receptor modulators and methods of use thereof |
ES2546410T3 (es) * | 2009-08-06 | 2015-09-23 | John Wayne Cancer Institute | Diagnosis de cáncer de mama, y otros tipos de cáncer, de tipo basal primario y metastásico |
BR112012009262A2 (pt) * | 2009-10-23 | 2019-09-24 | Health Research Inc | ''método para inibir a proliferação de células de câncer positivo para ar em um indivíduo diagnosticado com,ou qual se suspeita que tenha cânce positivo para ar e método para identificar se um indivíduo é um candidato para tratamento com uma composiçâo |
EP2523556A4 (en) | 2010-01-11 | 2013-08-28 | Gtx Inc | METHOD FOR TREATING MIBROMED DYNAMIC FUNCTION |
UY33740A (es) * | 2010-11-18 | 2012-05-31 | Takeda Pharmaceutical | Método para tratar el cáncer de mama y cáncer de ovarios |
US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
IN2015DN01046A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2012-07-13 | 2015-06-26 | Gtx Inc |
-
2013
- 2013-03-07 IN IN1046DEN2015 patent/IN2015DN01046A/en unknown
- 2013-03-07 JP JP2015521597A patent/JP6226978B2/ja active Active
- 2013-03-07 PT PT138172317T patent/PT2872482T/pt unknown
- 2013-03-07 MX MX2015000572A patent/MX375256B/es active IP Right Grant
- 2013-03-07 DK DK13817231.7T patent/DK2872482T3/da active
- 2013-03-07 HR HRP20201463TT patent/HRP20201463T1/hr unknown
- 2013-03-07 ES ES13817231T patent/ES2818915T3/es active Active
- 2013-03-07 CN CN201711417639.XA patent/CN108143728A/zh active Pending
- 2013-03-07 EP EP13817231.7A patent/EP2872482B1/en active Active
- 2013-03-07 KR KR1020207016499A patent/KR102238970B1/ko active Active
- 2013-03-07 RU RU2015104780A patent/RU2648959C2/ru active
- 2013-03-07 KR KR1020157003951A patent/KR102122941B1/ko active Active
- 2013-03-07 US US13/789,005 patent/US9604916B2/en active Active
- 2013-03-07 WO PCT/US2013/029667 patent/WO2014011220A2/en active Application Filing
- 2013-03-07 CN CN201911188725.7A patent/CN110840870A/zh active Pending
- 2013-03-07 RU RU2017141776A patent/RU2717835C2/ru active
- 2013-03-07 CA CA2879049A patent/CA2879049C/en active Active
- 2013-03-07 EP EP20179413.8A patent/EP3733170A1/en active Pending
- 2013-03-07 PL PL13817231T patent/PL2872482T3/pl unknown
- 2013-03-07 AU AU2013203600A patent/AU2013203600C1/en active Active
- 2013-03-07 LT LTEP13817231.7T patent/LT2872482T/lt unknown
- 2013-03-07 HU HUE13817231A patent/HUE052574T2/hu unknown
- 2013-03-07 CN CN201380040703.0A patent/CN104754939A/zh active Pending
-
2015
- 2015-01-12 IL IL236681A patent/IL236681B/en active IP Right Grant
- 2015-01-13 MX MX2020009725A patent/MX2020009725A/es unknown
-
2016
- 2016-06-03 AU AU2016203696A patent/AU2016203696B2/en active Active
-
2017
- 2017-03-13 JP JP2017046924A patent/JP6386120B2/ja active Active
-
2018
- 2018-02-28 AU AU2018201450A patent/AU2018201450B2/en active Active
- 2018-08-08 JP JP2018149623A patent/JP6759290B2/ja active Active
-
2020
- 2020-09-09 CY CY20201100853T patent/CY1123542T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IN2015DN01046A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
IL279330A (en) | Combined treatment including antibodies against Claudin 18.2 for the treatment of cancer | |
IL276434A (en) | Combined treatment involving antibodies against claudin 18.2 for the treatment of cancer | |
MX2018006477A (es) | Anticuerpos y metodos de uso de estos. | |
PH12019500261B1 (en) | Methods for treating osteogenesis imperfecta | |
NZ707086A (en) | Anti-cd40 antibodies and methods of use | |
MX2016001901A (es) | Biomarcadores para tratamiento de trastornos neoplasicos usando terapias dirigidas con andrógeno. | |
MX2017004526A (es) | Terapia combinada de anticuerpos biespecificos especificos para fap y dr5 y agentes quimioterapeuticos. | |
IL239981A0 (en) | Combined therapy involving antibodies against claudin 18.2 for the treatment of cancer | |
TW201613887A (en) | Antiproliferative compounds and methods of use thereof | |
MY191608A (en) | Treatment of cancer using anti-cd19 chimeric antigen receptor | |
MX2020009223A (es) | Anticuerpos anti-fgfr2iiib afucosilados. | |
MX2013009732A (es) | Terapias de combinacion comprendiendo agentes anti-erbb3. | |
MX2014004074A (es) | Metodo de tratamiento de condiciones del higado utilizando antagonistas de notch2. | |
MX368508B (es) | Benralizumab para usarse en la reducción de la tasa de exacerbación de asma. | |
MX2019001977A (es) | Metodos y composiciones para tratar esclerosis multiple y trastornos relacionados. | |
MX2017011237A (es) | Alteracion del metabolismo de esteroides para el tratamiento de enfermedades dependientes de esteroides. | |
AR086390A1 (es) | Metodo para el tratamiento de malignidades solidas que incluyen malignidades solidas avanzadas o metastasicas | |
RS63738B1 (sr) | Kombinovana terapija koja uključuje antitela protiv klaudina 18.2 za lečenje kancera | |
MX2017013666A (es) | Terapia de combinacion de agente anti-fuctactico y agente de inmunoterapia y composiciones para el tratamiento de cancer. | |
MA40363A (fr) | Agents de liaison de rspo1 et leurs utilisations | |
IN2014CN02671A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
UA85798U (ru) | Способ лечения йодозависимых заболеваний щитовидной железы | |
TN2013000114A1 (en) | Methods and compositions for treating lung cancer | |
UA70225U (ru) | Применение композиции, содержащей мирамистин, в качестве лекарственного средства для лечения заболеваний горла |