US2466420A
(en)
|
1947-11-26 |
1949-04-05 |
Eastman Kodak Co |
Ketene condensation products with aldehydes
|
US3226394A
(en)
|
1964-06-16 |
1965-12-28 |
Shulton Inc |
Pyridylethylated anthranilamides and derivatives thereof
|
CH504416A
(de)
|
1966-12-05 |
1971-03-15 |
Ciba Geigy Ag |
Verfahren zur Herstellung von aromatischen Sulfamoylverbindungen
|
US4551540A
(en)
|
1983-01-17 |
1985-11-05 |
Borg-Warner Chemicals, Inc. |
Substituted 2,5-dimethylpyrroles
|
US5190541A
(en)
|
1990-10-17 |
1993-03-02 |
Boston Scientific Corporation |
Surgical instrument and method
|
EP1306095A3
(en)
|
1992-03-05 |
2003-06-25 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
US5474765A
(en)
|
1992-03-23 |
1995-12-12 |
Ut Sw Medical Ctr At Dallas |
Preparation and use of steroid-polyanionic polymer-based conjugates targeted to vascular endothelial cells
|
US5686472A
(en)
|
1992-10-29 |
1997-11-11 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5593992A
(en)
|
1993-07-16 |
1997-01-14 |
Smithkline Beecham Corporation |
Compounds
|
WO1996011932A1
(en)
|
1994-10-14 |
1996-04-25 |
Smithkline Beecham Plc |
2-(imidazol-4-yl)carbapeneme derivatives, intermediates thereof and use as antibacterials
|
DE29624503U1
(de)
|
1995-04-19 |
2004-09-16 |
Boston Scientific Scimed, Inc. |
Arzneimittel-freisetzender beschichteter Stent
|
US6117432A
(en)
|
1995-04-20 |
2000-09-12 |
Societe D'exploitation De Produits Pour Les Industries Chimiques (S.E.P.P.I.C.) |
Therapeutic composition comprising an antigen or an in vivo generator of a compound comprising an amino acid sequence
|
TW349948B
(en)
|
1995-10-31 |
1999-01-11 |
Janssen Pharmaceutica Nv |
Farnesyl transferase inhibiting 2-quinolone derivatives
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
ES2260156T3
(es)
|
1995-12-08 |
2006-11-01 |
Janssen Pharmaceutica N.V. |
Derivados de (imidazol-5-il)metil-2-quinolinona como inhibidores de la proteina farnesil-transferasa.
|
US5874442A
(en)
|
1995-12-22 |
1999-02-23 |
Schering-Plough Corporation |
Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease
|
US6011029A
(en)
|
1996-02-26 |
2000-01-04 |
Bristol-Myers Squibb Company |
Inhibitors of farnesyl protein transferase
|
US5702390A
(en)
|
1996-03-12 |
1997-12-30 |
Ethicon Endo-Surgery, Inc. |
Bioplar cutting and coagulation instrument
|
EP0923557A4
(en)
|
1996-08-09 |
1999-12-08 |
Merck & Co Inc |
Stereoselective deoxygenation reaction
|
DE69725604T2
(de)
|
1996-12-20 |
2005-03-03 |
Sergazy Mynzhasarovich Adekenov |
VERFAHREN UND GERÄT ZUR HERSTELLUNG VPM LYOPHILISIERTEM 1ß, 10ß-EPOXY-13-DIMETHYLAMINO-GUAIA-3(4)-EN-6,12-OLID-HYDROCHLORID
|
UA59384C2
(uk)
|
1996-12-20 |
2003-09-15 |
Пфайзер, Інк. |
Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
|
TW591030B
(en)
|
1997-03-10 |
2004-06-11 |
Janssen Pharmaceutica Nv |
Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
|
HUP0001122A3
(en)
|
1997-04-25 |
2002-03-28 |
Janssen Pharmaceutica Nv |
Farnesyltransferase inhibiting quinazolinones
|
TW491872B
(en)
|
1997-05-27 |
2002-06-21 |
Ciba Sc Holding Ag |
Block oligomers containing l-hydrocarbyloxy-2,2,6,6-tetramethyl-4- piperidyl groups as stabilizers for lower polyolefin
|
US6100254A
(en)
|
1997-10-10 |
2000-08-08 |
Board Of Regents, The University Of Texas System |
Inhibitors of protein tyrosine kinases
|
DE69902012T2
(de)
|
1998-03-05 |
2002-11-21 |
Formula One Administration Ltd |
Datenübertragungssystem
|
US6303654B1
(en)
|
1998-03-12 |
2001-10-16 |
Wisconsin Alumni Research Foundation |
Acyclic monoterpenoid derivatives
|
WO2000001691A1
(en)
|
1998-07-01 |
2000-01-13 |
Merck & Co., Inc. |
Process for making farnesyl-protein transferase inhibitors
|
CA2336848A1
(en)
|
1998-07-10 |
2000-01-20 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
ID27562A
(id)
|
1998-08-27 |
2001-04-12 |
Pfizer Prod Inc |
Turunan-turunan kinolin-2-ona tersubstitusi alkunil yang berguna sebagai zat anti kanker
|
CA2341739C
(en)
|
1998-08-27 |
2005-07-12 |
Pfizer Products Inc. |
Quinolin-2-one derivatives useful as anticancer agents
|
GB9824579D0
(en)
|
1998-11-10 |
1999-01-06 |
Novartis Ag |
Organic compounds
|
SI1140935T1
(en)
|
1998-12-23 |
2003-10-31 |
Janssen Pharmaceutica N.V. |
1,2-annelated quinoline derivatives
|
DE1140938T1
(de)
|
1999-01-11 |
2003-01-09 |
Princeton University, Princeton |
Kinase-inhibitoren mit hoher affinität zur ziel detektion und ihre verwendung
|
PT1169038E
(pt)
|
1999-04-15 |
2012-10-26 |
Bristol Myers Squibb Co |
Inibidores cíclicos da proteína tirosina cinase
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
US6524583B1
(en)
|
1999-04-28 |
2003-02-25 |
Board Of Regents, The University Of Texas System |
Antibody methods for selectively inhibiting VEGF
|
US6346625B1
(en)
|
1999-06-23 |
2002-02-12 |
Astrazeneca Ab |
Protein kinase inhibitors
|
DE19962924A1
(de)
|
1999-12-24 |
2001-07-05 |
Bayer Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
ES2335265T3
(es)
|
1999-12-28 |
2010-03-24 |
Pharmacopeia, Inc. |
Inhibidores de citoquina, especialmente de tnf-alfa.
|
FR2803592A1
(fr)
|
2000-01-06 |
2001-07-13 |
Aventis Cropscience Sa |
Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant.
|
US6558385B1
(en)
|
2000-09-22 |
2003-05-06 |
Tissuelink Medical, Inc. |
Fluid-assisted medical device
|
US6692491B1
(en)
|
2000-03-24 |
2004-02-17 |
Scimed Life Systems, Inc. |
Surgical methods and apparatus for positioning a diagnostic or therapeutic element around one or more pulmonary veins or other body structures
|
US6776796B2
(en)
|
2000-05-12 |
2004-08-17 |
Cordis Corportation |
Antiinflammatory drug and delivery device
|
DE60113286T2
(de)
|
2000-10-17 |
2006-06-22 |
Merck & Co., Inc. |
Oral aktive salze mit tyrosinkinaseaktivität
|
US6958243B2
(en)
*
|
2000-12-14 |
2005-10-25 |
Biotage Ab |
Organic reactions with CO generating materials
|
US7105682B2
(en)
|
2001-01-12 |
2006-09-12 |
Amgen Inc. |
Substituted amine derivatives and methods of use
|
TWI238824B
(en)
|
2001-05-14 |
2005-09-01 |
Novartis Ag |
4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
|
WO2003024969A1
(en)
|
2001-09-14 |
2003-03-27 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
WO2003024931A1
(en)
|
2001-09-14 |
2003-03-27 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
TWI259081B
(en)
|
2001-10-26 |
2006-08-01 |
Sugen Inc |
Treatment of acute myeloid leukemia with indolinone compounds
|
US7973031B2
(en)
|
2001-10-30 |
2011-07-05 |
Novartis Ag |
Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity
|
KR100965519B1
(ko)
|
2001-12-27 |
2010-06-23 |
세라밴스 인코포레이티드 |
단백질 키나제 억제제로서 유용한 인돌리논 유도체
|
EP1513821B1
(en)
|
2002-05-23 |
2007-10-31 |
Cytopia PTY Ltd |
Protein kinase inhibitors
|
TW200406374A
(en)
|
2002-05-29 |
2004-05-01 |
Novartis Ag |
Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
JP4741948B2
(ja)
|
2002-08-14 |
2011-08-10 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
プロテインキナーゼインヒビターおよびそれらの使用
|
JP4613130B2
(ja)
|
2002-08-23 |
2011-01-12 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
ベンゾイミダゾールキノリノンおよびそれらの使用
|
AU2003258491A1
(en)
|
2002-09-05 |
2004-03-29 |
Neurosearch A/S |
Amide derivatives and their use as chloride channel blockers
|
US7208493B2
(en)
|
2002-10-03 |
2007-04-24 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
AU2003280599A1
(en)
|
2002-10-29 |
2004-05-25 |
Kirin Beer Kabushiki Kaisha |
QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF Flt3 AND MEDICINAL COMPOSITIONS CONTAINING THE SAME
|
WO2004043389A2
(en)
|
2002-11-13 |
2004-05-27 |
Chiron Corporation |
Methods of treating cancer and related methods
|
AR042052A1
(es)
|
2002-11-15 |
2005-06-08 |
Vertex Pharma |
Diaminotriazoles utiles como inhibidores de proteinquinasas
|
DE60326646D1
(de)
|
2002-12-18 |
2009-04-23 |
Vertex Pharma |
Benzisoxazolderivate, die sich als inhibitoren von proteinkinasen eigen
|
KR20050119201A
(ko)
|
2003-04-09 |
2005-12-20 |
니뽄 다바코 산교 가부시키가이샤 |
5원 헤테로방향족 고리 화합물 및 이의 의약적 용도
|
US7427683B2
(en)
*
|
2003-04-25 |
2008-09-23 |
Ortho-Mcneil Pharmaceutical, Inc. |
c-fms kinase inhibitors
|
US7790724B2
(en)
|
2003-04-25 |
2010-09-07 |
Janssen Pharmaceutica N.V. |
c-fms kinase inhibitors
|
WO2004096795A2
(en)
|
2003-04-25 |
2004-11-11 |
3-Dimensional Pharmaceuticals, Inc. |
C-fms kinase inhibitors
|
US20050113566A1
(en)
|
2003-04-25 |
2005-05-26 |
Player Mark R. |
Inhibitors of C-FMS kinase
|
WO2005012220A2
(en)
|
2003-07-28 |
2005-02-10 |
Smithkline Beecham Corporation |
Cycloalkylidene compounds as modulators of estrogen receptor
|
ATE465731T1
(de)
|
2003-10-23 |
2010-05-15 |
Ab Science |
2-aminoaryloxazol-verbindungen als tyrosinkinase- hemmer
|
GB0326601D0
(en)
|
2003-11-14 |
2003-12-17 |
Novartis Ag |
Organic compounds
|
CA2554925A1
(en)
|
2004-01-30 |
2005-08-11 |
Ab Science |
2-(3-substituted-aryl)amino-4-aryl-thiazoles as tyrosine kinase inhibitors
|
US7662837B2
(en)
|
2004-10-22 |
2010-02-16 |
Janssen Pharmaceutica N.V. |
Inhibitors of c-fms kinase
|
PT1807077T
(pt)
|
2004-10-22 |
2017-01-06 |
Janssen Pharmaceutica Nv |
Inibidores de quinase c-fms
|
US7645755B2
(en)
|
2004-10-22 |
2010-01-12 |
Janssen Pharmaceutical N.V. |
Inhibitors of c-fms kinase
|
DE602005015742D1
(de)
|
2004-10-22 |
2009-09-10 |
Janssen Pharmaceutica Nv |
Aromatische amide als hemmer der c-fms-kinase
|
US20060281771A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using aminoquinoline and aminoquinazoline kinase modulators
|
US20060281755A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators
|
US20060281788A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor
|
US20060281700A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using aminopyrimidines kinase modulators
|
US20060281769A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using thienopyrimidine and thienopyridine kinase modulators
|
CN101340909B
(zh)
|
2005-10-18 |
2012-01-11 |
詹森药业有限公司 |
抑制flt3激酶的方法
|
US8697716B2
(en)
|
2006-04-20 |
2014-04-15 |
Janssen Pharmaceutica Nv |
Method of inhibiting C-KIT kinase
|
US7414050B2
(en)
|
2006-04-20 |
2008-08-19 |
Janssen Pharmaceutica, N.V. |
Inhibitors of c-fms kinase
|
JP5331680B2
(ja)
|
2006-04-20 |
2013-10-30 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
c−fmsキナーゼの阻害剤
|
US8674100B2
(en)
|
2006-04-20 |
2014-03-18 |
Janssen Pharmaceutica, N.V. |
Inhibitors of C-FMS kinase
|
WO2008082490A2
(en)
*
|
2006-12-20 |
2008-07-10 |
Schering Corporation |
Novel jnk inhibitors
|
WO2008138184A1
(fr)
*
|
2007-05-14 |
2008-11-20 |
Shanghai Hengrui Pharmaceutical Co.Ltd. |
Dérivés de pyrrolo-azacycles, leur procédé de fabrication et leur utilisation en tant qu'inhibiteurs de protéine kinases
|
JO3240B1
(ar)
|
2007-10-17 |
2018-03-08 |
Janssen Pharmaceutica Nv |
c-fms مثبطات كيناز
|
EP2215482A2
(en)
|
2007-10-31 |
2010-08-11 |
Janssen Pharmaceutica N.V. |
Biomarker for assessing response to fms treatment
|
CN102361859A
(zh)
*
|
2008-12-30 |
2012-02-22 |
米伦纽姆医药公司 |
用作Raf激酶抑制剂的杂芳基化合物
|
JP2011026305A
(ja)
*
|
2009-06-24 |
2011-02-10 |
Daiichi Sankyo Co Ltd |
イミダゾールカルボニル化合物を含有する医薬組成物
|
MY184074A
(en)
*
|
2009-09-28 |
2021-03-17 |
Hoffmann La Roche |
Benzoxazepin p13k inhibitors compounds and methods of use
|
EP2525659B1
(en)
*
|
2010-01-19 |
2019-02-27 |
Merck Sharp & Dohme Corp. |
PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS
|
JP6359537B2
(ja)
*
|
2012-08-07 |
2018-07-18 |
ヤンセン ファーマシューティカ エヌ.ベー. |
複素環エステル誘導体の調製プロセス
|