IN2014MU00675A - - Google Patents
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- Publication number
- IN2014MU00675A IN2014MU00675A IN675MU2014A IN2014MU00675A IN 2014MU00675 A IN2014MU00675 A IN 2014MU00675A IN 675MU2014 A IN675MU2014 A IN 675MU2014A IN 2014MU00675 A IN2014MU00675 A IN 2014MU00675A
- Authority
- IN
- India
- Prior art keywords
- preparation
- relates
- present
- dabigatran etexilate
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN675MU2014 IN2014MU00675A (sl) | 2014-02-26 | 2015-02-23 | |
| PCT/IN2015/000100 WO2015128875A2 (en) | 2014-02-26 | 2015-02-23 | A process for preparation of dabigatran etexilate mesylate and intermediates thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN675MU2014 IN2014MU00675A (sl) | 2014-02-26 | 2015-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MU00675A true IN2014MU00675A (sl) | 2015-10-23 |
Family
ID=53267425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN675MU2014 IN2014MU00675A (sl) | 2014-02-26 | 2015-02-23 |
Country Status (2)
| Country | Link |
|---|---|
| IN (1) | IN2014MU00675A (sl) |
| WO (1) | WO2015128875A2 (sl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105732433A (zh) * | 2016-04-13 | 2016-07-06 | 山东新华制药股份有限公司 | 达比加群酯中间体缩合物的精制方法 |
| CN110878083A (zh) * | 2018-09-05 | 2020-03-13 | 连云港恒运药业有限公司 | 一种达比加群酯中间体的纯化方法 |
| CN111690699A (zh) * | 2020-05-19 | 2020-09-22 | 浙江工业大学 | 一种酶促在线合成3-（吡啶-2-氨基）丙羟肟酸的方法 |
| CN114113346B (zh) * | 2020-08-25 | 2024-01-12 | 石药集团恩必普药业有限公司 | 一种达比加群酯原料药或制剂中对甲苯磺酸乙酯、对甲苯磺酸异丙酯的检测方法 |
| CN114716411B (zh) * | 2022-04-29 | 2024-03-15 | 天方药业有限公司 | 一种从生产母液中回收制备甲磺酸达比加群酯的方法 |
| CN115417855A (zh) * | 2022-09-22 | 2022-12-02 | 安徽美诺华药物化学有限公司 | 一种达比加群酯甲磺酸盐的合成工艺 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE121699A1 (es) | 1997-02-18 | 1999-12-08 | Boehringer Ingelheim Pharma | Heterociclos biciclicos disustituidos como inhibidores de la trombina |
| US20050107409A1 (en) * | 2003-03-10 | 2005-05-19 | Boehringer Ingelheim International Gmbh | Aromatic bicyclic compounds, preparation thereof and their use as pharmaceutical compositions |
| DE10339862A1 (de) * | 2003-08-29 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel |
| EP1609784A1 (de) | 2004-06-25 | 2005-12-28 | Boehringer Ingelheim Pharma GmbH & Co.KG | Verfahren zur Herstellung von 4-(Benzimidazolylmethylamino)-Benzamidinen |
| DE102005025728A1 (de) | 2005-06-04 | 2006-12-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Polymorphe von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-Propionsäure-ethylester |
| ITTO20050486A1 (it) | 2005-07-14 | 2005-10-13 | Dumitru Bucuresteanu | Compressore ad aria funzionante a elica continua in un tubo girevole |
| DE102006054005A1 (de) | 2006-11-16 | 2008-05-21 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Polymorphe von 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester |
| CZ305085B6 (cs) * | 2008-03-14 | 2015-04-29 | Zentiva, K.S. | Způsob přípravy dabigatranu |
| CZ2008669A3 (cs) | 2008-10-24 | 2010-05-05 | Zentiva, A. S. | Zpusob prípravy dabigatranu a jeho meziprodukty |
| HUP1100244A2 (hu) | 2011-05-11 | 2012-11-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Gyógyszeripari intermedierek és eljárás elõállításukra |
| EP2522662A1 (en) * | 2011-05-11 | 2012-11-14 | Medichem, S.A. | Dabigatran etexilate and related substances, processes and compositions, and use of the substances as reference standards and markers |
-
2015
- 2015-02-23 IN IN675MU2014 patent/IN2014MU00675A/en unknown
- 2015-02-23 WO PCT/IN2015/000100 patent/WO2015128875A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015128875A3 (en) | 2015-11-12 |
| WO2015128875A2 (en) | 2015-09-03 |
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