WO2017037743A3 - Dabigatran etexilate 1,4-butanedisulfonate salt and its crystal form - Google Patents
Dabigatran etexilate 1,4-butanedisulfonate salt and its crystal form Download PDFInfo
- Publication number
- WO2017037743A3 WO2017037743A3 PCT/IN2016/050290 IN2016050290W WO2017037743A3 WO 2017037743 A3 WO2017037743 A3 WO 2017037743A3 IN 2016050290 W IN2016050290 W IN 2016050290W WO 2017037743 A3 WO2017037743 A3 WO 2017037743A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- crystal form
- dabigatran etexilate
- salt
- butanedisulfonate
- butanedisulfonate salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
The present invention provides a 1:1 salt of dabigatran etexilate with 1,4-butanedisulfonic acid, its crystal form and process for its preparation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN3391MU2015 | 2015-09-03 | ||
IN3391/MUM/2015 | 2015-09-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2017037743A2 WO2017037743A2 (en) | 2017-03-09 |
WO2017037743A3 true WO2017037743A3 (en) | 2018-09-27 |
Family
ID=58186977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2016/050290 WO2017037743A2 (en) | 2015-09-03 | 2016-09-02 | Dabigatran etexilate 1,4-butanedisulfonate salt and its crystal form |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2017037743A2 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2305665A1 (en) * | 2005-06-04 | 2011-04-06 | Boehringer Ingelheim International GmbH | Polymorphs of 3-[(2-{[4-(hexyloxy carbonyl amino-imino-methyl)-phenyl amino]methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propion acid-ethyl ester |
CN103864756A (en) * | 2012-12-11 | 2014-06-18 | 四川海思科制药有限公司 | Butanedisulfonic acid dabigatran etexilate and preparation method and application thereof |
WO2015124764A1 (en) * | 2014-02-24 | 2015-08-27 | Erregierre S.P.A. | Synthesis process of dabigatran etexilate mesylate, intermediates of the process and novel polymorph of dabigatran etexilate |
-
2016
- 2016-09-02 WO PCT/IN2016/050290 patent/WO2017037743A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2305665A1 (en) * | 2005-06-04 | 2011-04-06 | Boehringer Ingelheim International GmbH | Polymorphs of 3-[(2-{[4-(hexyloxy carbonyl amino-imino-methyl)-phenyl amino]methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propion acid-ethyl ester |
CN103864756A (en) * | 2012-12-11 | 2014-06-18 | 四川海思科制药有限公司 | Butanedisulfonic acid dabigatran etexilate and preparation method and application thereof |
WO2015124764A1 (en) * | 2014-02-24 | 2015-08-27 | Erregierre S.P.A. | Synthesis process of dabigatran etexilate mesylate, intermediates of the process and novel polymorph of dabigatran etexilate |
Also Published As
Publication number | Publication date |
---|---|
WO2017037743A2 (en) | 2017-03-09 |
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