IN2014MN02522A - - Google Patents
Download PDFInfo
- Publication number
- IN2014MN02522A IN2014MN02522A IN2522MUN2014A IN2014MN02522A IN 2014MN02522 A IN2014MN02522 A IN 2014MN02522A IN 2522MUN2014 A IN2522MUN2014 A IN 2522MUN2014A IN 2014MN02522 A IN2014MN02522 A IN 2014MN02522A
- Authority
- IN
- India
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/49—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12174020 | 2012-06-28 | ||
| PCT/EP2013/063488 WO2014001442A1 (en) | 2012-06-28 | 2013-06-27 | Designed ankyrin repeat proteins binding to platelet-derived growth factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02522A true IN2014MN02522A (es) | 2015-07-17 |
Family
ID=48699826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2522MUN2014 IN2014MN02522A (es) | 2012-06-28 | 2014-12-11 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9163070B2 (es) |
| EP (1) | EP2867360B1 (es) |
| JP (1) | JP2015522576A (es) |
| KR (1) | KR20150023957A (es) |
| CN (1) | CN104508129A (es) |
| AU (1) | AU2013283296A1 (es) |
| BR (1) | BR112014032316A2 (es) |
| CA (1) | CA2877584A1 (es) |
| HK (1) | HK1209156A1 (es) |
| IL (1) | IL236428A0 (es) |
| IN (1) | IN2014MN02522A (es) |
| MX (1) | MX2014015825A (es) |
| RU (1) | RU2014150224A (es) |
| SG (1) | SG11201408196RA (es) |
| WO (1) | WO2014001442A1 (es) |
| ZA (1) | ZA201408872B (es) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| JP6173216B2 (ja) | 2010-11-26 | 2017-08-02 | モレキュラー・パートナーズ・アーゲーＭｏｌｅｃｕｌａｒ Ｐａｒｔｎｅｒｓ Ａｇ | 設計アンキリンリピートタンパク質のための改善されたキャッピングモジュール |
| DK2846836T3 (da) | 2012-05-07 | 2019-11-11 | Allergan Inc | Fremgangsmåde til behandling af amd hos patienter, der er refraktære overfor anti-vegf-terapi |
| EP2738180A1 (en) | 2012-11-30 | 2014-06-04 | Molecular Partners AG | Binding proteins comprising at least two binding domains against HER2. |
| JP6486908B2 (ja) | 2013-05-31 | 2019-03-20 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 肝細胞増殖因子に結合する設計アンキリン反復タンパク質 |
| ES2834849T3 (es) | 2014-07-07 | 2021-06-18 | Yeda Res & Dev | Método de diseño computacional de proteínas |
| WO2016023898A2 (en) * | 2014-08-11 | 2016-02-18 | Medimmune Limited | Intracellular antigen binding |
| SG11201703428SA (en) | 2014-11-10 | 2017-05-30 | Hoffmann La Roche | Bispecific antibodies and methods of use in ophthalmology |
| CN107074942A (zh) | 2014-11-10 | 2017-08-18 | 豪夫迈·罗氏有限公司 | 抗‑IL‑1β抗体和使用方法 |
| WO2016075036A1 (en) | 2014-11-10 | 2016-05-19 | F. Hoffmann-La Roche Ag | Anti-pdgf-b antibodies and methods of use |
| KR20170082594A (ko) | 2014-11-10 | 2017-07-14 | 에프. 호프만-라 로슈 아게 | 항-ang2 항체 및 사용 방법 |
| ES2953482T3 (es) | 2015-04-02 | 2023-11-13 | Molecular Partners Ag | Dominios de repetición de anquirina diseñados con especificidad de unión para la albúmina sérica |
| US10283384B2 (en) * | 2015-04-27 | 2019-05-07 | Taiwan Semiconductor Manufacturing Co., Ltd. | Method for etching etch layer and wafer etching apparatus |
| ES2953516T3 (es) | 2016-09-22 | 2023-11-14 | Molecular Partners Ag | Proteínas de unión recombinantes y su uso |
| US10037890B2 (en) * | 2016-10-11 | 2018-07-31 | Lam Research Corporation | Method for selectively etching with reduced aspect ratio dependence |
| WO2018165046A1 (en) | 2017-03-07 | 2018-09-13 | Igc Bio, Inc. | A computational pipeline for antibody modeling and design |
| EP3623382A1 (en) | 2018-09-14 | 2020-03-18 | Universität Zürich | Ligands to gm-csf or gm-csf-receptor for use in leukemia in a patient having undergone allo-hct |
| US11655293B2 (en) | 2018-02-22 | 2023-05-23 | Universitat Zurich | Ligands to GM-CSF or GM-CSF-receptor for use in leukemia in a patient having undergone allo-HCT |
| WO2019180243A1 (en) | 2018-03-22 | 2019-09-26 | Charité-Universitätsmedizin Berlin | Crispr associated protein reactive t cell immunity |
| EP3807401A1 (en) | 2018-06-15 | 2021-04-21 | Universität Bern | LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES |
| JP2022504472A (ja) | 2018-10-08 | 2022-01-13 | ウニベルシテート チューリッヒ | Ｈｅｒ２結合四量体ポリペプチド |
| WO2020104627A1 (en) | 2018-11-21 | 2020-05-28 | Universität Zürich | Photochemically induced conjugation of radiometals to small molecules, peptides and nanoparticles in a simultaneous one-pot reaction |
| EP3677911A3 (en) | 2019-01-03 | 2020-07-29 | Universität Basel | Use of non-agonist ligands for suppression of metastasis |
| WO2020144378A1 (en) | 2019-01-11 | 2020-07-16 | Universitätsspital Basel | Sglt-2 inhibitors or il-1r antagonists for reduction of hypoglycaemia after bariatric surgery |
| EP3953712A1 (en) | 2019-04-10 | 2022-02-16 | Universität Zürich | A method for determining the likelihood of a patient being responsive to cancer immunotherapy |
| UY38739A (es) | 2019-06-04 | 2020-12-31 | Molecular Partners Ag | Proteínas multiespecíficas |
| EP3980045A1 (en) * | 2019-06-04 | 2022-04-13 | Molecular Partners AG | Recombinant fap binding proteins and their use |
| WO2021044050A1 (en) | 2019-09-05 | 2021-03-11 | Genome Biologics Ug | Inhibition of mthfd1l for use in hypertrophic heart disease and heart failure |
| CN115003689A (zh) | 2019-12-11 | 2022-09-02 | 分子合作伙伴股份公司 | 具有改变的表面残基的经设计的锚蛋白重复结构域 |
| WO2021122813A1 (en) | 2019-12-16 | 2021-06-24 | Universität Basel | Angiogenesis promoting agents for prevention of metastatic cancer |
| WO2021176008A1 (en) | 2020-03-04 | 2021-09-10 | Cornell University | Agents targeting baf155 or brg1 for use in treatment of advanced prostate cancer |
| WO2021204781A1 (en) | 2020-04-06 | 2021-10-14 | Universität Zürich | Artc1 ligands for cancer treatment |
| JP2023525518A (ja) | 2020-05-06 | 2023-06-16 | モレキュラー パートナーズ アクチェンゲゼルシャフト | 新規アンキリンリピート結合タンパク質とその用途 |
| AU2021271129A1 (en) | 2020-05-14 | 2022-12-15 | Molecular Partners Ag | Multispecific proteins |
| WO2021239844A1 (en) | 2020-05-27 | 2021-12-02 | Universitätsspital Basel | Sglt-2 inhibitors or il-1r antagonists for reduction of hypoglycaemia in prediabetes |
| WO2021239999A1 (en) | 2020-05-28 | 2021-12-02 | Universität Zürich | Il-12 pd-l1 ligand fusion protein |
| WO2022038193A1 (en) | 2020-08-18 | 2022-02-24 | Universität Zürich | A cd25-biased anti-il-2 antibody |
| US20240108746A1 (en) | 2020-12-16 | 2024-04-04 | Molecular Partners Ag | Novel slow-release prodrugs |
| WO2022171831A1 (en) | 2021-02-11 | 2022-08-18 | Universität Zürich | Use of markers found on lymph node metastatic samples for the prognosis of breast cancer |
| EP4304729A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Novel darpin based cd123 engagers |
| EP4305063A1 (en) | 2021-03-09 | 2024-01-17 | Molecular Partners AG | Protease cleavable prodrugs |
| BR112023018293A2 (pt) | 2021-03-09 | 2023-10-31 | Molecular Partners Ag | Acopladores de célula t multiespecíficos à base de darpin |
| WO2022190010A1 (en) | 2021-03-09 | 2022-09-15 | Molecular Partners Ag | Novel darpin based cd33 engagers |
| CA3227299A1 (en) | 2021-08-05 | 2023-02-09 | Immunos Therapeutics Ag | Pharmaceutical compositions comprising hla fusion proteins |
| IL310617A (en) | 2021-08-05 | 2024-04-01 | Immunos Therapeutics Ag | Combination drugs that include HLA FUSION proteins |
| WO2023021006A1 (en) | 2021-08-16 | 2023-02-23 | Universität Zürich | Il-1 targeting agents for treatment of pitiyriasis rubra pilaris |
| WO2023036849A1 (en) | 2021-09-07 | 2023-03-16 | ETH Zürich | Identifying and predicting future coronavirus variants |
| EP4163380A1 (en) | 2021-10-08 | 2023-04-12 | ETH Zurich | Device and method for manipulation of extracellular vesicles |
| WO2023110983A1 (en) | 2021-12-14 | 2023-06-22 | Molecular Partners Ag | Designed repeat domains with dual binding specificity and their use |
| WO2023110942A1 (en) | 2021-12-14 | 2023-06-22 | Charité-Universitätsmedizin Berlin | Prevention of impaired fracture healing |
| EP4260907A1 (en) | 2022-04-11 | 2023-10-18 | Universität Zürich | Agents for treatment of endometriosis and other benign gynecological neoplasms |
| WO2024002914A1 (en) | 2022-06-27 | 2024-01-04 | Charité-Universitätsmedizin Berlin | Prediction of, and composition to improve, tendon healing |
| WO2024028278A1 (en) | 2022-08-01 | 2024-02-08 | Molecular Partners Ag | Charge modified designed repeat domains and their use |
| WO2024038307A1 (en) | 2022-08-19 | 2024-02-22 | Novartis Ag | Dosing regimens for sars-cov-2 binding molecules |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5094941A (en) * | 1987-12-31 | 1992-03-10 | Zymogenetics, Inc. | Monoclonal antibodies to PDGF |
| ATE151110T1 (de) | 1988-09-02 | 1997-04-15 | Protein Eng Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| US5348867A (en) | 1991-11-15 | 1994-09-20 | George Georgiou | Expression of proteins on bacterial surface |
| CA2196496A1 (en) | 1997-01-31 | 1998-07-31 | Stephen William Watson Michnick | Protein fragment complementation assay for the detection of protein-protein interactions |
| WO1998048008A1 (en) | 1997-04-23 | 1998-10-29 | Plueckthun Andreas | Methods for identifying nucleic acid molecules encoding (poly)peptides that interact with target molecules |
| WO2000032823A1 (en) | 1998-12-02 | 2000-06-08 | Phylos, Inc. | Dna-protein fusions and uses thereof |
| CA2421447C (en) * | 2000-09-08 | 2012-05-08 | Universitat Zurich | Collections of repeat proteins comprising repeat modules |
| JP2005512962A (ja) * | 2001-09-20 | 2005-05-12 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 抗ｐｄｇｆ抗体および設計抗体の産生方法 |
| CN102813923B (zh) * | 2003-08-27 | 2015-04-01 | 奥普索特克公司 | 用于治疗眼新血管疾病的组合治疗 |
| US20080206201A1 (en) * | 2004-11-12 | 2008-08-28 | Rudolf Beier | Recombinant Newcastle Disease Virus |
| WO2006129828A2 (en) * | 2005-05-31 | 2006-12-07 | Canon Kabushiki Kaisha | Target substance capturing molecule |
| AU2006268780B2 (en) | 2005-07-08 | 2011-03-24 | University Of Zurich | Phage display using cotranslational translocation of fusion polypeptides |
| EP1996220B2 (en) | 2006-03-06 | 2023-08-16 | Amunix Operating Inc. | Unstructured recombinant polymers and uses thereof |
| SI2173890T1 (sl) | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
| AU2008328726B2 (en) * | 2007-11-30 | 2014-06-12 | Glaxo Group Limited | Antigen-binding constructs |
| WO2009100990A1 (en) * | 2008-02-13 | 2009-08-20 | Dsm Ip Assets B.V. | Process for the production of a peptide |
| WO2009115919A2 (en) * | 2008-03-19 | 2009-09-24 | Institut Pasteur | Reagentless fluorescent biosensors comprising a designed ankyrin repeat protein module, rational design methods to create reagentless fluorescent biosensors and methods of their use |
| US8901076B2 (en) | 2008-11-03 | 2014-12-02 | Molecular Partner AG | Binding proteins inhibiting the VEGF-A receptor interaction |
| TW201120210A (en) * | 2009-11-05 | 2011-06-16 | Hoffmann La Roche | Glycosylated repeat-motif-molecule conjugates |
| AR081361A1 (es) | 2010-04-30 | 2012-08-29 | Molecular Partners Ag | Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a |
| JP6173216B2 (ja) * | 2010-11-26 | 2017-08-02 | モレキュラー・パートナーズ・アーゲーＭｏｌｅｃｕｌａｒ Ｐａｒｔｎｅｒｓ Ａｇ | 設計アンキリンリピートタンパク質のための改善されたキャッピングモジュール |
| EP2702069A4 (en) * | 2011-04-29 | 2015-04-29 | Janssen Biotech Inc | IL4 / IL13 BINDING REPEAT PROTEINS AND USES THEREOF |
-
2013
- 2013-06-27 RU RU2014150224A patent/RU2014150224A/ru not_active Application Discontinuation
- 2013-06-27 BR BR112014032316A patent/BR112014032316A2/pt not_active IP Right Cessation
- 2013-06-27 KR KR20157002327A patent/KR20150023957A/ko not_active Application Discontinuation
- 2013-06-27 SG SG11201408196RA patent/SG11201408196RA/en unknown
- 2013-06-27 WO PCT/EP2013/063488 patent/WO2014001442A1/en active Application Filing
- 2013-06-27 EP EP13731809.3A patent/EP2867360B1/en active Active
- 2013-06-27 JP JP2015519089A patent/JP2015522576A/ja active Pending
- 2013-06-27 US US13/928,973 patent/US9163070B2/en active Active
- 2013-06-27 AU AU2013283296A patent/AU2013283296A1/en not_active Abandoned
- 2013-06-27 CN CN201380034192.1A patent/CN104508129A/zh active Pending
- 2013-06-27 MX MX2014015825A patent/MX2014015825A/es unknown
- 2013-06-27 CA CA2877584A patent/CA2877584A1/en not_active Abandoned
-
2014
- 2014-12-03 ZA ZA2014/08872A patent/ZA201408872B/en unknown
- 2014-12-11 IN IN2522MUN2014 patent/IN2014MN02522A/en unknown
- 2014-12-24 IL IL236428A patent/IL236428A0/en unknown
-
2015
- 2015-09-08 US US14/847,403 patent/US20150368302A1/en not_active Abandoned
- 2015-10-07 HK HK15109777.3A patent/HK1209156A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1209156A1 (en) | 2016-03-24 |
| US20150368302A1 (en) | 2015-12-24 |
| JP2015522576A (ja) | 2015-08-06 |
| CN104508129A (zh) | 2015-04-08 |
| AU2013283296A1 (en) | 2015-02-05 |
| EP2867360A1 (en) | 2015-05-06 |
| MX2014015825A (es) | 2015-08-10 |
| CA2877584A1 (en) | 2014-01-03 |
| IL236428A0 (en) | 2015-02-26 |
| US20140005125A1 (en) | 2014-01-02 |
| KR20150023957A (ko) | 2015-03-05 |
| EP2867360B1 (en) | 2019-05-08 |
| SG11201408196RA (en) | 2015-03-30 |
| WO2014001442A1 (en) | 2014-01-03 |
| BR112014032316A2 (pt) | 2017-06-27 |
| ZA201408872B (en) | 2016-05-25 |
| US9163070B2 (en) | 2015-10-20 |
| RU2014150224A (ru) | 2016-08-20 |