IN2014MN02126A - - Google Patents
Info
- Publication number
- IN2014MN02126A IN2014MN02126A IN2126MUN2014A IN2014MN02126A IN 2014MN02126 A IN2014MN02126 A IN 2014MN02126A IN 2126MUN2014 A IN2126MUN2014 A IN 2126MUN2014A IN 2014MN02126 A IN2014MN02126 A IN 2014MN02126A
- Authority
- IN
- India
- Prior art keywords
- compounds
- calcium
- crac
- channel
- formula
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 2
- 150000001669 calcium Chemical class 0.000 abstract 2
- 229910052791 calcium Inorganic materials 0.000 abstract 2
- 239000011575 calcium Substances 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2126MUN2014 IN2014MN02126A (enrdf_load_stackoverflow) | 2012-05-02 | 2013-05-01 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN6KO2012 | 2012-05-02 | ||
| PCT/IB2013/053440 WO2013164769A1 (en) | 2012-05-02 | 2013-05-01 | Substituted pyridine compounds as crac modulators |
| IN2126MUN2014 IN2014MN02126A (enrdf_load_stackoverflow) | 2012-05-02 | 2013-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014MN02126A true IN2014MN02126A (enrdf_load_stackoverflow) | 2015-09-11 |
Family
ID=48428565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2126MUN2014 IN2014MN02126A (enrdf_load_stackoverflow) | 2012-05-02 | 2013-05-01 |
Country Status (7)
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US9242969B2 (en) | 2013-03-14 | 2016-01-26 | Novartis Ag | Biaryl amide compounds as kinase inhibitors |
| AU2014282769A1 (en) | 2013-06-21 | 2015-12-17 | Lupin Limited | Substituted heterocyclic compounds as CRAC modulators |
| AU2014300629A1 (en) | 2013-06-24 | 2015-12-24 | Lupin Limited | Chromane and chromene derivatives and their use as CRAC modulators |
| WO2015090579A1 (en) * | 2013-12-18 | 2015-06-25 | Grünenthal GmbH | Pyrazolyl-based carboxamides iv |
| CN105367547B (zh) * | 2014-08-19 | 2019-04-23 | 北京桦冠生物技术有限公司 | 一种噁唑啉酮抗生素的新合成工艺 |
| UY36294A (es) | 2014-09-12 | 2016-04-29 | Novartis Ag | Compuestos y composiciones como inhibidores de quinasa |
| HK1243636A1 (zh) * | 2014-11-18 | 2018-07-20 | Rutgers, The State University Of New Jersey | 用於治疗代谢疾病和癌症的新的线粒体解偶联剂 |
| EP3261641B1 (en) * | 2015-02-27 | 2023-07-12 | Calcimedica, Inc. | Pancreatitis treatment |
| WO2016187182A1 (en) | 2015-05-18 | 2016-11-24 | Beth Israel Deaconess Medical Center, Inc. | Substance p, mast cell degranulation inhibitors, and peripheral neuropathy |
| HUE045546T2 (hu) * | 2015-06-03 | 2020-01-28 | Bristol Myers Squibb Co | 4-hidroxi-3-(heteroaril)piridin-2-on APJ agonisták felhasználásra cardiovascularis megbetegedések kezelésében |
| DK3331525T3 (da) | 2015-08-07 | 2020-12-14 | Calcimedica Inc | Anvendelse af CRAC-kanal-inhibitorer til behandling af slagtilfælde og traumatisk hjerneskade |
| CN109415363B (zh) | 2016-05-18 | 2021-07-20 | 罗格斯，新泽西州立大学 | 用于治疗代谢疾病和癌症的新的线粒体解偶联剂 |
| JP7114575B2 (ja) | 2016-09-19 | 2022-08-08 | ノバルティス アーゲー | Ｒａｆ阻害剤及びｅｒｋ阻害剤を含む治療用組合せ |
| MX393855B (es) | 2017-05-02 | 2025-03-21 | Novartis Ag | Terapia de combinación que comprende un inhibidor de raf y trametinib |
| CA3085460A1 (en) * | 2017-12-22 | 2019-06-27 | Petra Pharma Corporation | Aryl-bipyridine amine derivatives as phosphatidylinositol phosphate kinase inhibitors |
| PE20251292A1 (es) | 2018-03-08 | 2025-05-14 | Incyte Corp | Compuestos diolicos de aminopirazina como inhibidores de pi3k-gamma |
| WO2020010003A1 (en) | 2018-07-02 | 2020-01-09 | Incyte Corporation | AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS |
| US20220040162A1 (en) | 2018-09-14 | 2022-02-10 | Rhizen Pharmaceuticals Ag | Compositions comprising a crac inhibitor and a corticosteroid and methods of use thereof |
| EP4563150A3 (en) | 2019-05-13 | 2025-07-23 | Novartis AG | New crystalline forms of n-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methvlphenyl)-2(trifluoromethyl) isonicotinamide as raf inhibitors for the treatment of cancer |
| CN110407740A (zh) * | 2019-09-04 | 2019-11-05 | 上海毕得医药科技有限公司 | 一种3-溴-2-乙基吡啶的合成方法 |
| WO2023210599A1 (ja) | 2022-04-25 | 2023-11-02 | 日本新薬株式会社 | Ｄｄｒ１キナーゼ阻害剤としての化合物および医薬 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004259347B2 (en) | 2003-07-23 | 2011-02-24 | Synta Pharmaceuticals, Corp. | Method for modulating calcium ion-release-activated calcium ion channels |
| KR20070057965A (ko) | 2004-09-21 | 2007-06-07 | 신타 파마슈티칼스 코프. | 염증 및 면역 관련 용도를 위한 화합물 |
| CA2593550A1 (en) | 2005-01-07 | 2006-08-10 | Synta Pharmaceutical Corp. | Compounds for inflammation and immune-related uses |
| AU2006208043B2 (en) | 2005-01-25 | 2012-09-20 | Synta Pharmaceuticals Corp. | Thiophene compounds for inflammation and immune-related uses |
| WO2006081391A2 (en) | 2005-01-25 | 2006-08-03 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| US8623871B2 (en) | 2006-01-25 | 2014-01-07 | Synta Pharmaceuticals Corp. | Substituted biaryl compounds for inflammation and immune-related uses |
| TWI417096B (zh) | 2006-01-25 | 2013-12-01 | Synta Pharmaceuticals Corp | 用於發炎及免疫相關用途之苯基及吡啶基化合物 |
| US8741960B2 (en) | 2006-01-25 | 2014-06-03 | Synta Pharmaceuticals Corp. | Substituted aromatic compounds for inflammation and immune-related uses |
| PL1984338T3 (pl) | 2006-01-31 | 2013-06-28 | Synta Pharmaceuticals Corp | Związki pirydylofenylowe do zastosowań związanych z zapaleniami i odpornością |
| AU2007286807B2 (en) | 2006-08-21 | 2013-03-21 | Genentech, Inc. | Aza-benzothiophenyl compounds and methods of use |
| JP5431323B2 (ja) | 2007-08-01 | 2014-03-05 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連用途のためのピリジン化合物 |
| RU2492168C2 (ru) | 2007-08-17 | 2013-09-10 | Актелион Фармасьютиклз Лтд | Производные пиридина в качестве модуляторов s1p1/edg1 рецептора |
| JP5411141B2 (ja) | 2007-09-10 | 2014-02-12 | カルシメディカ，インク． | 細胞内カルシウムを調節する化合物 |
| WO2009076454A2 (en) | 2007-12-12 | 2009-06-18 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| AU2009248786B2 (en) | 2008-05-23 | 2013-04-04 | Glaxo Group Limited | Tricyclic nitrogen containing compounds and their use as antibacterials |
| DE102008031299B4 (de) | 2008-07-02 | 2014-10-30 | Acandis Gmbh & Co. Kg | Filter für ein Blutgefäß |
| RU2472791C2 (ru) | 2008-08-27 | 2013-01-20 | КалсиМедика Инк. | Соединения, модулирующие внутриклеточный кальций |
| US8524763B2 (en) | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| JP2012504605A (ja) | 2008-10-01 | 2012-02-23 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連使用のための化合物 |
| UY32856A (es) | 2009-08-26 | 2011-03-31 | Astrazeneca Ab | Derivados heterocíclicos de urea y métodos de uso de los mismos |
| EP2477982A4 (en) | 2009-09-16 | 2013-04-03 | Calcimedica Inc | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM |
| BR112013010643A2 (pt) | 2010-10-30 | 2016-08-09 | Lupin Ltd | compostos heterocíclicos |
| CN103702665B (zh) | 2011-05-03 | 2016-08-17 | 幸讬制药公司 | 用于炎症和免疫相关用途的化合物 |
| AU2012325901A1 (en) | 2011-10-19 | 2014-05-15 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| WO2013059677A1 (en) | 2011-10-19 | 2013-04-25 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
-
2013
- 2013-05-01 IN IN2126MUN2014 patent/IN2014MN02126A/en unknown
- 2013-05-01 WO PCT/IB2013/053440 patent/WO2013164769A1/en not_active Ceased
- 2013-05-01 AU AU2013255437A patent/AU2013255437A1/en not_active Abandoned
- 2013-05-01 EP EP13722111.5A patent/EP2844655A1/en not_active Withdrawn
- 2013-05-01 CA CA2871270A patent/CA2871270A1/en not_active Abandoned
- 2013-05-01 US US14/398,154 patent/US9399638B2/en not_active Expired - Fee Related
-
2014
- 2014-10-22 ZA ZA2014/07685A patent/ZA201407685B/en unknown
-
2016
- 2016-06-20 US US15/186,882 patent/US20160304506A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160304506A1 (en) | 2016-10-20 |
| CA2871270A1 (en) | 2013-11-07 |
| EP2844655A1 (en) | 2015-03-11 |
| ZA201407685B (en) | 2015-11-25 |
| WO2013164769A1 (en) | 2013-11-07 |
| AU2013255437A1 (en) | 2014-11-13 |
| US9399638B2 (en) | 2016-07-26 |
| US20150111900A1 (en) | 2015-04-23 |
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