HK1220699A1 - 治療神經退行性蛋白質病的化合物 - Google Patents

治療神經退行性蛋白質病的化合物

Info

Publication number
HK1220699A1
HK1220699A1 HK16108680.0A HK16108680A HK1220699A1 HK 1220699 A1 HK1220699 A1 HK 1220699A1 HK 16108680 A HK16108680 A HK 16108680A HK 1220699 A1 HK1220699 A1 HK 1220699A1
Authority
HK
Hong Kong
Prior art keywords
compunds
treating neurodegenerative
neurodegenerative proteinopathies
proteinopathies
treating
Prior art date
Application number
HK16108680.0A
Other languages
English (en)
Inventor
Todd E Golde
Paramita Chakrabarty
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of HK1220699A1 publication Critical patent/HK1220699A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
HK16108680.0A 2013-03-15 2016-07-20 治療神經退行性蛋白質病的化合物 HK1220699A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361802184P 2013-03-15 2013-03-15
PCT/US2014/029202 WO2014144686A1 (en) 2013-03-15 2014-03-14 Compunds for treating neurodegenerative proteinopathies

Publications (1)

Publication Number Publication Date
HK1220699A1 true HK1220699A1 (zh) 2017-05-12

Family

ID=51537756

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108680.0A HK1220699A1 (zh) 2013-03-15 2016-07-20 治療神經退行性蛋白質病的化合物

Country Status (7)

Country Link
US (2) US10030067B2 (zh)
EP (1) EP2970428A4 (zh)
JP (1) JP2016516053A (zh)
AU (1) AU2014228886B2 (zh)
CA (1) CA2942514A1 (zh)
HK (1) HK1220699A1 (zh)
WO (1) WO2014144686A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10030067B2 (en) 2013-03-15 2018-07-24 University Of Florida Research Foundation, Incorporated Compounds for treating neurodegenerative proteinopathies
KR102176284B1 (ko) * 2015-04-08 2020-11-09 삼성전기주식회사 디지털 촬영시스템 및 그 제어방법
US10230888B2 (en) * 2015-07-31 2019-03-12 Qualcomm Incorporated Sensor-based camera initialization
KR20200134212A (ko) * 2018-01-02 2020-12-01 러쉬 유니버시티 메디컬 센터 신경계 장애 및 기타 장애를 치료하기 위한 조성물 및 방법
CN114901275A (zh) 2019-12-20 2022-08-12 纳米医疗有限公司 可用于治疗癌症的含有Toll样受体(“TLR”)激动剂前药的配制和/或共同配制的脂质体组合物及其方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1288226A1 (en) * 2001-09-03 2003-03-05 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Modification of the expression levels of Toll-like receptor familiy members for influencing neurodegeneration and neuroprotection in the human central nervous system
ATE418346T1 (de) * 2004-04-08 2009-01-15 Sangamo Biosciences Inc Zusammensetzungen zur behandlung von neuropathischen und neurodegenerativen erkrankungen
WO2007001332A2 (en) * 2004-08-04 2007-01-04 University Of Massachusetts Anti-pathogen immunoadhesins
CA2604515A1 (en) 2005-04-18 2006-10-26 The Provost, Fellows And Scholars Of The College Of The Holy And Undivid Ed Trinity Of Queen Elizabeth, Near Dublin Toll-like receptor 14 (tlr14 ) and use thereof
US20070275416A1 (en) * 2006-05-16 2007-11-29 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Affinity marker for purification of proteins
JP5554703B2 (ja) * 2007-06-28 2014-07-23 オプソナ セラピューティクス リミテッド 自己免疫疾患の治療のための組成物および方法
WO2009090493A2 (en) * 2007-12-06 2009-07-23 Korea Advanced Institute Of Science And Technology Tlr4 decoy receptor protein
CA2737549A1 (en) * 2008-09-16 2010-03-25 Luke Anthony John O'neill Compositions and methods for modulating toll-like receptor activity
JP2012504651A (ja) * 2008-10-02 2012-02-23 ヤンセン バイオテツク，インコーポレーテツド Ｔｏｌｌ様受容体の活性を抑制するための方法
WO2012016973A1 (en) * 2010-08-02 2012-02-09 Transmit Gmbh Invention related to contact allergens
BR112014000055A2 (pt) * 2011-07-01 2017-06-13 Bayer Ip Gmbh polipeptídeos de fusão de relaxina e usos dos mesmos
US10030067B2 (en) 2013-03-15 2018-07-24 University Of Florida Research Foundation, Incorporated Compounds for treating neurodegenerative proteinopathies

Also Published As

Publication number Publication date
AU2014228886A1 (en) 2015-10-29
AU2014228886B2 (en) 2018-11-29
US20180355018A1 (en) 2018-12-13
US11345738B2 (en) 2022-05-31
EP2970428A1 (en) 2016-01-20
JP2016516053A (ja) 2016-06-02
US10030067B2 (en) 2018-07-24
EP2970428A4 (en) 2016-08-31
US20160024178A1 (en) 2016-01-28
CA2942514A1 (en) 2014-09-18
WO2014144686A1 (en) 2014-09-18

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