IN2014KN01374A - - Google Patents

Info

Publication number
IN2014KN01374A
IN2014KN01374A IN1374KON2014A IN2014KN01374A IN 2014KN01374 A IN2014KN01374 A IN 2014KN01374A IN 1374KON2014 A IN1374KON2014 A IN 1374KON2014A IN 2014KN01374 A IN2014KN01374 A IN 2014KN01374A
Authority
IN
India
Prior art keywords
resistance
cells
identification
generation
cell cultures
Prior art date
Application number
Other languages
English (en)
Inventor
Ulrich Elling
Josef Penninger
Jasmin Taubenschmid
Original Assignee
Imba Inst Für Molekulare Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imba Inst Für Molekulare Biotechnologie Gmbh filed Critical Imba Inst Für Molekulare Biotechnologie Gmbh
Publication of IN2014KN01374A publication Critical patent/IN2014KN01374A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
IN1374KON2014 2011-11-30 2012-11-30 IN2014KN01374A (enExample)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11191408.1A EP2599859A1 (en) 2011-11-30 2011-11-30 Haploid cells
US201161565626P 2011-12-01 2011-12-01
PCT/EP2012/074112 WO2013079670A1 (en) 2011-11-30 2012-11-30 Haploid cells

Publications (1)

Publication Number Publication Date
IN2014KN01374A true IN2014KN01374A (enExample) 2015-10-16

Family

ID=45218335

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1374KON2014 IN2014KN01374A (enExample) 2011-11-30 2012-11-30

Country Status (11)

Country Link
US (1) US20140342369A1 (enExample)
EP (2) EP2599859A1 (enExample)
JP (1) JP2015500637A (enExample)
KR (1) KR20140101390A (enExample)
CN (1) CN104024404A (enExample)
AU (1) AU2012343826A1 (enExample)
CA (1) CA2856810A1 (enExample)
IL (1) IL232879A0 (enExample)
IN (1) IN2014KN01374A (enExample)
SG (1) SG11201402350QA (enExample)
WO (1) WO2013079670A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2681310B2 (en) * 2011-03-02 2020-01-22 Anton Wutz Mammalian haploid embryonic stem cells
WO2015152146A1 (ja) * 2014-03-31 2015-10-08 国立大学法人東京医科歯科大学 1倍体胚性幹細胞の培養方法
CN117431206A (zh) * 2015-07-29 2024-01-23 纽约干细胞基金会有限公司 单倍体人胚胎干细胞系和体细胞系及其制备方法
EP3472342A1 (en) * 2016-06-19 2019-04-24 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Screening for chemotherapy resistance in human haploid cells
EP3491131B1 (en) 2016-07-29 2022-05-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Targeted in situ protein diversification by site directed dna cleavage and repair
EP3388530A1 (en) 2017-04-13 2018-10-17 IMBA-Institut für Molekulare Biotechnologie GmbH Nucleic acid modification and identification method
JP7341891B2 (ja) 2017-04-13 2023-09-11 イーエムベーアー-インスティテュート フュール モレクラレ バイオテクノロジー ゲゼルシャフト ミット ベシュレンクテル ハフツング 核酸を修飾して同定する方法
CN108998410B (zh) * 2017-06-07 2020-11-06 中国科学院动物研究所 蛋白激酶抑制剂在抑制单倍体细胞二倍化中的用途
CN107217042B (zh) * 2017-07-31 2020-03-06 江苏东抗生物医药科技有限公司 一种生产无岩藻糖基化蛋白的基因工程细胞系及其建立方法
US10626319B1 (en) 2019-05-17 2020-04-21 King Fahd University Of Petroleum And Minerals Methods of inhibiting corrosion with a pyrazine corrosion inhibitor
US20230313130A1 (en) * 2020-07-17 2023-10-05 Tohoku University Trophoblast stem cell-like cells capable of differentiating into placenta-constituting cells, and method for producing same
CN118370275B (zh) * 2024-06-21 2024-09-06 中国科学院昆明动物研究所 一种产生母源性半克隆小鼠的方法
CN118389411A (zh) * 2024-06-21 2024-07-26 中国科学院昆明动物研究所 一种小鼠双单倍体胚胎干细胞分离建系的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
EP1092768A1 (en) 1999-10-16 2001-04-18 ARTEMIS Pharmaceuticals GmbH Conditional gene trapping construct for the disruption of genes
JP2003514516A (ja) 1999-10-28 2003-04-22 ユニバーシティ オブ マサチューセッツ 多能性細胞と細胞株の雌性発生的または雄性発生的産生および分化した細胞と組織を産生するためのその使用
CA2388510A1 (en) 1999-11-02 2001-05-10 James M. Robl Use of haploid genomes for genetic diagnosis, modification and multiplication
US7074611B2 (en) 2001-04-27 2006-07-11 Gie-Cerbn, Centre Europeen De Recherche En Biologie Et En Medecine (Gie) Method for the stable inversion of DNA sequence by site-specific recombination and DNA vectors and transgenic cells thereof
WO2004053078A2 (en) 2002-12-09 2004-06-24 Boehringer Ingelheim Pharmaceuticals, Inc. METHODS FOR MODULATING IKKα ACTIVITY
PT1572984E (pt) 2002-12-16 2016-06-03 Technion Res & Dev Foundation Sistema de cultura para células estaminais embrionárias humanas sem células alimentadoras e sem xeno
EP1662005A1 (en) 2004-11-26 2006-05-31 FrankGen Biotechnologie AG Enhancer-containing gene trap vectors for random and targeted gene trapping
DE602005026221D1 (de) 2004-11-26 2011-03-17 Frankgen Biotechnologie Ag Gen-fallen-kassette für eine gerichtete und ungerichtete konditionelle geninaktivierung
WO2008033469A1 (en) 2006-09-15 2008-03-20 Children's Medical Center Corporation Methods for producing embryonic stem cells from parthenogenetic embryos
CN101715485A (zh) * 2007-04-06 2010-05-26 国际干细胞公司 源于人单性生殖胚泡的患者特异性干细胞系
EP2681310B2 (en) 2011-03-02 2020-01-22 Anton Wutz Mammalian haploid embryonic stem cells

Also Published As

Publication number Publication date
AU2012343826A1 (en) 2014-06-12
EP2785832A1 (en) 2014-10-08
SG11201402350QA (en) 2014-06-27
US20140342369A1 (en) 2014-11-20
CN104024404A (zh) 2014-09-03
IL232879A0 (en) 2014-07-31
WO2013079670A1 (en) 2013-06-06
KR20140101390A (ko) 2014-08-19
CA2856810A1 (en) 2013-06-06
JP2015500637A (ja) 2015-01-08
EP2599859A1 (en) 2013-06-05

Similar Documents

Publication Publication Date Title
MY183741A (en) Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
NZ627373A (en) Genes involved in noscapine production
MX362523B (es) Direccion transmitida por nucleasa con vectores de direccion grandes.
PH12012501746A1 (en) Polynucleotide molecules for gene regulation in plants
ZA201606933B (en) Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
IL252045B (en) Isolated nucleic acid, expression vector and cell culture comprising the nucleic acid
MX421064B (es) Composiciones de nanoparticulas lipidicas y metodos para administracion de arnm
SG10201809901SA (en) Generating Pluripotent Cells De Novo
NZ628549A (en) Novel class of glyphosate resistance genes
PH12015501470A1 (en) Compositions and methods for the control of nematodes and soil borne diseases
NZ811395A (en) Mutated protoporphyrinogen ix oxidase (ppx) genes
PL2975115T3 (pl) Materiał pochodzenia roślinnego do hodowli komórek
MX347810B (es) Métodos para mejorar el rendimiento y la tolerancia al estrés en una planta.
PH12015500213A1 (en) Production of fmdv-resistant livestock by allele substitution
MX2013007689A (es) Moleculas de acido nucleico que confieren resistencia a pestes de coleopteran.
MX2014014650A (es) Minivectores superenrollados como una herramienta para la reparacion, alteración y reemplazo de ácido desoxirribonucleico.
WO2012142116A3 (en) Identification and use of krp mutants in wheat
MX2020010524A (es) Composiciones y metodos para inhibir la expresion del gen de alfa-1 antitripsina.
SG195304A1 (en) Genetic manipulation and expression systems for pucciniomycotina and ustilaginomycotina subphyla
EP3042180A4 (en) Cell culturing and tracking with oled arrays
IN2015KN00073A (enExample)
MX2016004597A (es) Interferencia de la represion del factor de transcripcion hd-zip de expresion genica para la produccion de plantas con rasgos mejorados.
MY171760A (en) Microorganisms and methods for the production of caprolactone
MY191390A (en) Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair
MX349339B (es) Gen y variaciones asociadas con el fenotipo bm1, marcadores moleculares, y su uso.